Research Topics
Species | P T JohnsonSummaryAffiliation: University of California Country: USA Publications
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Publications
Distribution, size and number of axons in the optic pathway of ground squirrelsP T Johnson
Neuroscience Research Institute, University of California, Santa Barbara 93106 5060, USA
Exp Brain Res 118:93-104. 1998....
Synaptic pathology, altered gene expression, and degeneration in photoreceptors impacted by drusenPatrick T Johnson
Center for the Study of Macular Degeneration, Neuroscience Research Institute, University of California, Santa Barbara, California 93106 5060, USA
Invest Ophthalmol Vis Sci 46:4788-95. 2005..Drusen are risk factors for age-related macular degeneration and have been shown to negatively impact cells of the RPE and retina. In this study, the effects of drusen on the synaptic machinery of retinal photoreceptors are investigated...
Drusen-associated degeneration in the retinaPatrick T Johnson
Neuroscience Research Institute, University of California, Santa Barbara, California 93106, USA
Invest Ophthalmol Vis Sci 44:4481-8. 2003..The purpose of this study was to investigate the impact of drusen on overlying cells of the retina...
Development of cholinergic amacrine cell stratification in the ferret retina and the effects of early excitotoxic ablationB E Reese
Neuroscience Research Institute, University of California at Santa Barbara, 93106 5060, USA
Vis Neurosci 18:559-70. 2001..While these cholinergic amacrine cells are present well before other cell types have differentiated, apparently neither they, nor the ganglion cells, play a role in determining the depth of stratification for other retinal cell types...
Chronotopic fiber reordering and the distribution of cell adhesion and extracellular matrix molecules in the optic pathway of fetal ferretsB E Reese
Neuroscience Research Institute, University of California at Santa Barbara 93106, USA
J Comp Neurol 380:355-72. 1997..The CSPGs may do so by interfering with adhesion molecules on optic axons that normally promote elongation...
Disruption of transient photoreceptor targeting within the inner plexiform layer following early ablation of cholinergic amacrine cells in the ferretP T Johnson
Neuroscience Research Institute, University of California at Santa Barbara, 93106-5060, USA
Vis Neurosci 18:741-51. 2001..These results strongly suggest that the targeting of the photoreceptor terminals to discrete strata within the IPL is dependent upon the cholinergic amacrine cell processes...
Developmental patterns of protein expression in photoreceptors implicate distinct environmental versus cell-intrinsic mechanismsP T Johnson
Neuroscience Research Institute, and Department of Molecular, Cellular and Developmental Biology, University of California at Santa Barbara, 93106-5060, USA
Vis Neurosci 18:157-68. 2001....
Maturational gradients in the retina of the ferretB E Reese
Neuroscience Research Institute, University of California at Santa Barbara 93106 5060
J Comp Neurol 375:252-73. 1996..These results make clear that the order of retinal maturation and the formation of the area centralis are not linked, at least not in the ferret...
Individuals homozygous for the age-related macular degeneration risk-conferring variant of complement factor H have elevated levels of CRP in the choroidP T Johnson
Center for the Study of Macular Degeneration, Neuroscience Research Institute, University of California, Santa Barbara, CA 93106 5060, USA
Proc Natl Acad Sci U S A 103:17456-61. 2006....
Extrinsic modulation of retinal ganglion cell projections: analysis of the albino mutation in pigmentation mosaic miceD S Rice
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, Tennessee, 38105, USA
Dev Biol 216:41-56. 1999..These studies demonstrate that the albino mutation acts indirectly upon retinal ganglion cells, which in turn respond by making axonal guidance errors at the optic chiasm...
