Mahlon D Johnson

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. Carson Walter E, Winans B, Whiteman M, Liu Y, Jarvela S, Haapasalo H, et al. Characterization of TEM1/endosialin in human and murine brain tumors. BMC Cancer. 2009;9:417 pubmed publisher
    ..The cellular localization of TEM1/endosialin and its expression profile in primary and metastatic brain tumors support efforts to therapeutically target this protein, potentially via antibody mediated drug delivery strategies. ..
  2. Johnson M. Transforming Growth Factor Beta Family in the Pathogenesis of Meningiomas. World Neurosurg. 2017;104:113-119 pubmed publisher
    ..The TGF-β family may represent new targets for chemotherapy and could include inhibitors of kinases activated by TGF-β. ..
  3. request reprint
    Johnson M, Pace J, Burroughs J. Fourth ventricle rosette-forming glioneuronal tumor. Case report. J Neurosurg. 2006;105:129-31 pubmed
    ..Recognition of, and long-term follow up for, this recently described pathological entity may clarify the nature of this lesion and strategies for its optimal management. ..
  4. Johnson M, O Connell M, Vito F, Pilcher W. Bone morphogenetic protein 4 and its receptors are expressed in the leptomeninges and meningiomas and signal via the Smad pathway. J Neuropathol Exp Neurol. 2009;68:1177-83 pubmed publisher
    ..These findings suggest that BMP-4 and BMPRs may play autocrine/paracrine roles and interact with other transforming growth factor-beta superfamily members in regulating meningioma growth and differentiation. ..
  5. Johnson M, Vito F, Xu H, Xu H. MUC16 expression and risk of adenocarcinoma metastases to peritoneum, pleura, leptomeninges, and brain. Appl Immunohistochem Mol Morphol. 2010;18:250-3 pubmed publisher
    ..Our findings suggest that adenocarcinomas with MUC16 expression may have an increased risk for metastases to pleura/peritoneum but not the leptomeninges or brain. ..
  6. Johnson M, O CONNELL M. Na-K-2Cl cotransporter and aquaporin 1 in arachnoid granulations, meningiomas, and meningiomas invading dura. Hum Pathol. 2013;44:1118-24 pubmed publisher
    ..This was extensive in all subtypes of meningiomas studied. These findings suggest that NKCC1 and AQP1 participate in meningioma biology and invasion. NKCC1 might be targeted by FDA-approved NKCC1 inhibitors. ..

Detail Information

Publications6

  1. Carson Walter E, Winans B, Whiteman M, Liu Y, Jarvela S, Haapasalo H, et al. Characterization of TEM1/endosialin in human and murine brain tumors. BMC Cancer. 2009;9:417 pubmed publisher
    ..The cellular localization of TEM1/endosialin and its expression profile in primary and metastatic brain tumors support efforts to therapeutically target this protein, potentially via antibody mediated drug delivery strategies. ..
  2. Johnson M. Transforming Growth Factor Beta Family in the Pathogenesis of Meningiomas. World Neurosurg. 2017;104:113-119 pubmed publisher
    ..The TGF-β family may represent new targets for chemotherapy and could include inhibitors of kinases activated by TGF-β. ..
  3. request reprint
    Johnson M, Pace J, Burroughs J. Fourth ventricle rosette-forming glioneuronal tumor. Case report. J Neurosurg. 2006;105:129-31 pubmed
    ..Recognition of, and long-term follow up for, this recently described pathological entity may clarify the nature of this lesion and strategies for its optimal management. ..
  4. Johnson M, O Connell M, Vito F, Pilcher W. Bone morphogenetic protein 4 and its receptors are expressed in the leptomeninges and meningiomas and signal via the Smad pathway. J Neuropathol Exp Neurol. 2009;68:1177-83 pubmed publisher
    ..These findings suggest that BMP-4 and BMPRs may play autocrine/paracrine roles and interact with other transforming growth factor-beta superfamily members in regulating meningioma growth and differentiation. ..
  5. Johnson M, Vito F, Xu H, Xu H. MUC16 expression and risk of adenocarcinoma metastases to peritoneum, pleura, leptomeninges, and brain. Appl Immunohistochem Mol Morphol. 2010;18:250-3 pubmed publisher
    ..Our findings suggest that adenocarcinomas with MUC16 expression may have an increased risk for metastases to pleura/peritoneum but not the leptomeninges or brain. ..
  6. Johnson M, O CONNELL M. Na-K-2Cl cotransporter and aquaporin 1 in arachnoid granulations, meningiomas, and meningiomas invading dura. Hum Pathol. 2013;44:1118-24 pubmed publisher
    ..This was extensive in all subtypes of meningiomas studied. These findings suggest that NKCC1 and AQP1 participate in meningioma biology and invasion. NKCC1 might be targeted by FDA-approved NKCC1 inhibitors. ..