Research Topics
Species | John M JohnsonSummaryAffiliation: University of Texas Health Science Center Country: USA Publications
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Publications
Age of onset as a discriminator between alcoholic subtypes in a treatment-seeking outpatient populationB A Johnson
Department of Psychiatry, University of Texas, San Antonio 78284 7792, USA
Am J Addict 9:17-27. 2000..Yet, this clinical characterization would be clinically important if specific age of onset levels were found to be differentially sensitive to pharmacological and/or psychological treatments...
Exercise in a hot environment: the skin circulationJ M Johnson
Department of Physiology, University of Texas Health Science Center, San Antonio, Texas 78229, USA
Scand J Med Sci Sports 20:29-39. 2010..Internal temperature rises to levels that limit exercise through central thermal effects, rather than loss of blood pressure or a reduction in blood flow to active muscle...
Local thermal control of the human cutaneous circulationJohn M Johnson
Dept of Physiology, Univ of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio TX 78231, USA
J Appl Physiol 109:1229-38. 2010..The mechanism for that transient vasodilation is not known, but it is inhibited by intact sympathetic vasoconstrictor nerve function and by intact sensory nerve function...- Thermoregulatory and thermal control in the human cutaneous circulationJohn M Johnson
Department of Physiology, University of Texas Health Science Center, San Antonio, TX 78229, USA
Front Biosci (Schol Ed) 2:825-53. 2010.... - How does skin blood flow get so high?John M Johnson
J Physiol 577:768. 2006 - Sympathetic, sensory, and nonneuronal contributions to the cutaneous vasoconstrictor response to local coolingJohn M Johnson
Dept of Physiology MSC 7756, University of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio, TX 78229 3900, USA
Am J Physiol Heart Circ Physiol 288:H1573-9. 2005..Later, a vasoconstriction develops with or without functional sensory or sympathetic nerves... - How do veins talk to arteries?John M Johnson
Department of Physiology, University of Texas, Health Science Center at San Antonio, 7703 Floyd Curl Drive MSC 7756, San Antonio, TX 78229 3900, USA
J Physiol 538:341. 2002 - Neuropeptide Y antagonism reduces reflex cutaneous vasoconstriction in humansDan P Stephens
Department of Physiology, The University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
Am J Physiol Heart Circ Physiol 287:H1404-9. 2004..05) but not at sites treated with Yoh + Pro + BIBP-3226 (P > 0.05). These results indicate that NPY participates in sympathetically mediated cutaneous vasoconstriction in humans during whole body cooling... - The involvement of norepinephrine, neuropeptide Y, and nitric oxide in the cutaneous vasodilator response to local heating in humansGary J Hodges
Department of Physiology, The University of Texas Health Science Center, San Antonio, TX 78229 3900, USA
J Appl Physiol 105:233-40. 2008..Since VCN and NOS blockade in combination do not have an inhibition greater than either alone, these data suggest that VCN promote heat-induced vasodilation via a nitric oxide-dependent mechanism... - The role of baseline in the cutaneous vasoconstrictor responses during combined local and whole body cooling in humansGary J Hodges
Department of Physiology, The University of Texas Health Science Center, San Antonio, TX, USA
Am J Physiol Heart Circ Physiol 293:H3187-92. 2007..05); the responses at those latter sites were not different (P > 0.05), suggesting that the baseline change in CVC with LC is important in the attenuation of reflex vasoconstrictor responses to WBC... - Relative roles of local and reflex components in cutaneous vasoconstriction during skin cooling in humansGuy E Alvarez
Department of Physiology-MSC 7756, The University of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio, TX 78229-3900, USA
J Appl Physiol 100:2083-8. 2006..6+/-2 vs. 42.4+/-8%; P<0.05). Hence, LC contributes importantly to the reduction in SkBF with body cooling, but also suppresses the reflex response, resulting in a nonadditive effect of these two components... - Exogenous melatonin administration modifies cutaneous vasoconstrictor response to whole body skin cooling in humansKen Aoki
Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
J Pineal Res 44:141-8. 2008..These findings suggest that by affecting the vasoconstrictor system, melatonin has a causal role in the nocturnal changes in body temperature and its control... - The involvement of heating rate and vasoconstrictor nerves in the cutaneous vasodilator response to skin warmingGary J Hodges
Department of Physiology, The University of Texas Health Science Center, San Antonio, Texas, USA
Am J Physiol Heart Circ Physiol 296:H51-6. 2009..05), suggesting the absence of tonic activity in those conditions and therefore that the adrenergic components of the responses in part 1 are via the stimulation of the transmitter release by LH... - Evidence for a role for vasoactive intestinal peptide in active vasodilatation in the cutaneous vasculature of humansLee Ann T Bennett
Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
J Physiol 552:223-32. 2003..5 degrees C). VIP(10-28), alone or in combination with atropine, attenuated the increase in CVC during heat stress, suggesting an important role for VIP in AVD... - The involvement of nitric oxide in the cutaneous vasoconstrictor response to local cooling in humansGary J Hodges
Department of Physiology-MSC 7756, 7703 Floyd Curl Drive, San Antonio, TX 78229-3900, USA
J Physiol 574:849-57. 2006..These data suggest that the vasoconstriction with slow LC is due to a combination of increased noradrenaline release and decreased activity of both NOS per se and of process(es) downstream of NOS... - Modification of cutaneous vasodilator response to heat stress by daytime exogenous melatonin administrationKen Aoki
Department of Physiology, University of Texas Health Science Center, San Antonio, Texas, USA
Am J Physiol Regul Integr Comp Physiol 291:R619-24. 2006..Because control of SR and HR are also modified, a central action of melatonin is suggested... - Cutaneous vasoconstrictor response to whole body skin cooling is altered by time of dayKen Aoki
Department of Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
J Appl Physiol 94:930-4. 2003..Furthermore, the slope of the relationship between CVC and T(sk) is steeper in the PM compared with that in the AM... - Role of sensory nerves in the cutaneous vasoconstrictor response to local cooling in humansGary J Hodges
Department of Physiology MSC 7756, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
Am J Physiol Heart Circ Physiol 293:H784-9. 2007.... - Antagonism of soluble guanylyl cyclase attenuates cutaneous vasodilation during whole body heat stress and local warming in humansDean L Kellogg
Geriatric Research, Education, and Clinical Center, Department of Veterans Affairs, South Texas Veterans Health Care System, Audie L Murphy Memorial Veterans Hospital Division, San Antonio, Texas, USA
J Appl Physiol 110:1406-13. 2011..05 ODQ vs. DMSO or Ringer). sGC participates in neurogenic active vasodilation during heat stress and in the local response to direct skin warming... - Rate dependency and role of nitric oxide in the vascular response to direct cooling in human skinFumio Yamazaki
Department of Physiology, The University of Texas Health Science Center at San Antonio, Texas, USA
J Appl Physiol 100:42-50. 2006.... - VIP/PACAP receptor mediation of cutaneous active vasodilation during heat stress in humansDean L Kellogg
Division of Geriatrics and Gerontology, Department of Medicine, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA
J Appl Physiol 109:95-100. 2010..46 +/- 3%max, PACAP6-38 treated, P < 0.05). We conclude that VPAC2 and/or PAC1 receptor activation is involved in cutaneous active vasodilation in humans... - Adrenergic control of the human cutaneous circulationGary J Hodges
Department of Physiology, The University of Texas Health Science Center, San Antonio, TX 78229, USA
Appl Physiol Nutr Metab 34:829-39. 2009.... - Sympathetic nonnoradrenergic cutaneous vasoconstriction in women is associated with reproductive hormone statusDan P Stephens
Department of Physiology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, San Antonio, TX 78229-3900, USA
Am J Physiol Heart Circ Physiol 282:H264-72. 2002..After cooling, the effects of NE at YOPR sites were completely blocked. These data indicate that a nonnoradrenergic mechanism of reflex cutaneous vasoconstriction is present in women and is associated with reproductive hormone status... - Central command and the cutaneous vascular response to isometric exercise in heated humansManabu Shibasaki
Institute for Exercise and Environmental Medicine, Presbyterian Hospital of Dallas, 7232 Greenville Ave. Suite 435, Dallas, TX 75231, USA
J Physiol 565:667-73. 2005..These findings suggest that central command, as well as muscle metabo-sensitive afferent stimulation, contributes to forearm cutaneous vascular responses in heat stressed humans... - Body temperature regulation during hemodialysis in long-term patients: is it time to change dialysate temperature prescription?Pablo E Pergola
Division of Nephrology, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
Am J Kidney Dis 44:155-65. 2004..0 degrees C in all patients unless contraindicated... - Influence of hyperoxia on skin vasomotor control in normothermic and heat-stressed humansFumio Yamazaki
Department of Clinical Pathophysiology, School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan
J Appl Physiol 103:2026-33. 2007..We found no significant role for adrenergic mechanisms in hyperoxic vasoconstriction. Decreased production of vasodilator prostaglandins may play a role in hyperoxia-induced cutaneous vasoconstriction in heat-stressed humans... - Mechanisms of vasoconstriction with direct skin cooling in humansJohn M Johnson
Am J Physiol Heart Circ Physiol 292:H1690-1. 2007 - The cardiovascular challenge of exercising in the heatJose Gonzalez-Alonso
Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, Middlesex, UK
J Physiol 586:45-53. 2008..This review focuses on how the cardiovascular system is regulated when exercising in the heat and how restrictions in locomotor skeletal muscle and/or skin perfusion might limit athletic performance in hot environments... - Human medullary responses to cooling and rewarming the skin: a functional MRI studyRobin M McAllen
Howard Florey Institute of Experimental Physiology and Medicine, Department of Anatomy, University of Melbourne, Melbourne, Victoria 3010, Australia
Proc Natl Acad Sci U S A 103:809-13. 2006....
Research Grants
- Vasomotor Mechanisms in the Human Cutaneous CirculationJohn Johnson; Fiscal Year: 2007..Lastly, we will test for a functional role for sympathetic transmitters other than norepinephrine and NPY I the vasoconstrictor control of the cutaneous circulation, with particular emphasis on a potential role for ATP. ..
- MENSTRUAL PHASE AND NEURAL CONTROL OF SKIN BLOOD FLOWJohn Johnson; Fiscal Year: 2002..The role of prostaglandin synthesis in the upward shift of the thermoregulatory control of the active vasodilator system will also be evaluated. ..