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Genomes and GenesSpecies | Bankole A JohnsonSummaryAffiliation: University of Virginia Country: USA Publications
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Publications
A synopsis of the pharmacological rationale, properties and therapeutic effects of depot preparations of naltrexone for treating alcohol dependenceBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, PO Box 800623, Charlottesville, VA 22908 0623, USA
Expert Opin Pharmacother 7:1065-73. 2006..Naltrel helped reduce relapse and promote abstinence in two samples of alcohol-dependent individuals. Additional efficacy studies are warranted...
Topiramate for treating alcohol dependence: a randomized controlled trialBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908, USA
JAMA 298:1641-51. 2007....
Kinetic and cardiovascular comparison of immediate-release isradipine and sustained-release isradipine among non-treatment-seeking, cocaine-dependent individualsBankole A Johnson
South Texas Addiction Research and Technology Center, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
Prog Neuropsychopharmacol Biol Psychiatry 29:15-20. 2005..The more favorable cardiovascular profile of SR isradipine would, however, make it more appropriate as an investigational medication for the treatment of stimulant dependence and related neurovascular disorders...
Safety and efficacy of GABAergic medications for treating alcoholismBankole A Johnson
Department of Psychiatric Medicine, The University of Virginia, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 29:248-54. 2005..Johnson; (5) Evaluating the Risk of Benzodiazepine Prescription to Alcohol-Dependent Individuals, by Domenic A. Ciraulo; and (6) Safety and Efficacy of GABAergic Agents in Treating Alcoholics: Discussion, by Robert M. Swift...
Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findingsBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Biochem Pharmacol 75:34-56. 2008..As neuroscientific research progresses, other promising medications, as well as medication combinations, for treating alcohol dependence continue to be explored...
Acute intravenous low- and high-dose cocaine reduces quantitative global and regional cerebral blood flow in recently abstinent subjects with cocaine use disorderBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
J Cereb Blood Flow Metab 25:928-36. 2005..Increasingly larger doses of cocaine may be associated with greater risk for ischemic stroke...
A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of methamphetamine dependenceBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Int J Neuropsychopharmacol 11:1-14. 2008..These findings should be viewed in light of the possibility that a less intensive cognitive behavioural therapy regimen might have yielded more positive results in this initial phase II trial exploring for the efficacy of ondansetron...
Effects of isradipine, a dihydropyridine-class calcium-channel antagonist, on d-methamphetamine's subjective and reinforcing effectsBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
Int J Neuropsychopharmacol 8:203-13. 2005..Depending upon conditioning status, isradipine can reduce some methamphetamine-induced positive subjective and reinforcing effects associated with its abuse liability in methamphetamine addicts...
Effects of isradipine on cocaine-induced changes in cognitive performance in recently abstinent cocaine-dependent individualsBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
Int J Neuropsychopharmacol 8:549-56. 2005..Hence, cocaine-taking by cocaine-dependent individuals produces little improvement in cognitive performance and attention in either the presence or absence of isradipine...
Use of oral topiramate to promote smoking abstinence among alcohol-dependent smokers: a randomized controlled trialBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
Arch Intern Med 165:1600-5. 2005..Herein, we extend that proof-of-concept study by determining whether cigarette-smoking, alcohol-dependent individuals from the earlier study also experienced improved smoking outcomes...
Challenges and opportunities for medications development in alcoholism: an international perspective on collaborations between academia and industryBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
Alcohol Clin Exp Res 29:1528-40. 2005..Swift, MD, PhD; (4) A European Perspective on Medications Development, by Otto M. Lesch, MD, PhD, and (5) A Scandinavian Perspective on Evidence-Based Addiction Treatment, by Mats Berglund, MD...
Recent advances in the development of treatments for alcohol and cocaine dependence: focus on topiramate and other modulators of GABA or glutamate functionBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908, USA
CNS Drugs 19:873-96. 2005....
Kinetic and cardiovascular effects of acute topiramate dosing among non-treatment-seeking, methamphetamine-dependent individualsBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Prog Neuropsychopharmacol Biol Psychiatry 31:455-61. 2007..Larger laboratory studies with chronic dosing regimens are needed to establish whether or not there is a kinetic interaction between topiramate and methamphetamine...
Effects of acute topiramate dosing on methamphetamine-induced subjective moodBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
Int J Neuropsychopharmacol 10:85-98. 2007..Thus, testing chronically administered or higher doses, or both, of topiramate would be necessary to determine conclusively whether or not it can attenuate the positive subjective and reinforcing effects of methamphetamine...
Understanding and treating alcohol dependenceBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 30:567-84. 2006..Johnson, DSc, MD, PhD; and (5) Differential Effects of Pharmacological Agents on Craving, by Nassima Ait-Daoud, MD...
A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of cocaine dependenceBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Drug Alcohol Depend 84:256-63. 2006..04). These results suggest the possibility of a non-linear dose-response function, with evidence supporting efficacy for the 4.0 mg group...
Can serotonin transporter genotype predict serotonergic function, chronicity, and severity of drinking?Bankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Prog Neuropsychopharmacol Biol Psychiatry 32:209-16. 2008..Thus, 5-HTT expression varies with current and lifetime drinking in L-carriers alone...
Effects of topiramate on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition in recently abstinent methamphetamine-dependent individualsBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Prog Neuropsychopharmacol Biol Psychiatry 31:123-30. 2007..Topiramate's complicated cognitive effects among methamphetamine addicts need more comprehensive examination...
Medication treatment of different types of alcoholismBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, 22908 0623, USA
Am J Psychiatry 167:630-9. 2010..Brief behavioral interventions that encourage the patient to set goals for a reduction in heavy drinking or abstinence also are part of optimal therapy...
Topiramate in the new generation of drugs: efficacy in the treatment of alcoholic patientsBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Curr Pharm Des 16:2103-12. 2010..Preclinical information that topiramate may have differential effects based on genetic vulnerability opens up the possibility of future methods to optimize treatment...
Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinkingBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Am J Psychiatry 168:265-75. 2011....
Pills for speedballing or cocaine dependenceBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908, USA
Lancet 367:1714-6. 2006
Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the detailsBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, PO Box 800623, Charlottesville, VA 22908 0623, USA
Alcohol Clin Exp Res 35:572-80. 2011..Attention must be paid to the devil in the details...
Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trialBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
Arch Intern Med 168:1188-99. 2008..We sought to determine whether topiramate's antidrinking effects are bolstered by improvements in physical and psychosocial well-being...
Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognitionBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
Psychopharmacology (Berl) 178:296-302. 2005..Yet, isradipine's effects on cognitive performance in methamphetamine-dependent individuals are not known...
Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studiesBankole A Johnson
Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
Am J Hypertens 18:813-22. 2005..We therefore examined, in two separate experiments of similar design conducted contemporaneously, the hemodynamic effects of cocaine or methamphetamine in the presence and absence of isradipine...
Drinking histories in alcohol-use-disordered youth: preliminary findings on relationships to platelet serotonin transporter expression with genotypes of the serotonin transporterMichael A Dawes
Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
J Stud Alcohol Drugs 70:899-907. 2009..Specifically, we wanted to examine the relationships between the following: platelet 5-HTT and 5-HTT genotype; platelet 5-HTT parameters and age at onset, as well as duration of drinking; and 5-HTT genotype and impulse control...
Oral topiramate for treatment of alcohol dependence: a randomised controlled trialBankole A Johnson
Department of Psychiatry, University of Texas Health Science Center at San Antonio, TX 78229 3900, USA
Lancet 361:1677-85. 2003..We aimed to see whether topiramate was more effective than placebo as a treatment for alcohol dependence...
Platelet serotonin uptake and paroxetine binding among allelic genotypes of the serotonin transporter in alcoholicsMartin A Javors
South Texas Addiction Research and Technology START Center, and Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
Prog Neuropsychopharmacol Biol Psychiatry 29:7-13. 2005..Our findings in currently drinking alcoholics support the hypothesis that those with the LL genotype of the 5'-HTTLPR region of the 5-HTT gene have reduced 5-HTT function...
Effects of repeated-dose isradipine on the abuse liability of cocaineJohn D Roache
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, 78229, USA
Exp Clin Psychopharmacol 13:319-26. 2005..Isradipine enhanced, rather than antagonized, subjective effects, indicating that isradipine does not antagonize cocaine's abuse liability in dependent research volunteers...
Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trialBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 78229 3900, USA
Arch Gen Psychiatry 61:905-12. 2004..Topiramate, a fructopyranose derivative, was superior to placebo at improving the drinking outcomes of alcohol-dependent individuals...
Treating smoking dependence in depressed alcoholicsNassima Ait-Daoud
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia, USA
Alcohol Res Health 29:213-20. 2006..Additional treatment strategies targeting dually dependent individuals with comorbid psychiatric disorders, including special populations such as women and adolescents, await further investigation...
Effects of isradipine on cocaine-induced subjective moodBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
J Clin Psychopharmacol 24:180-91. 2004..Also, isradipine-mediated inhibition of mesolimbic DA release may be an ineffective treatment of cocaine dependence...
Can serotonin transporter genotype predict craving in alcoholism?Nassima Ait-Daoud
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 33:1329-35. 2009....
Comorbid alcohol and nicotine dependence: from the biomolecular basis to clinical consequencesNassima Ait-Daoud
Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
Alcohol Clin Exp Res 29:1541-9. 2005..Lesch, MD, PhD; and (5) Pharmacotherapy for Promotion of Abstinence from Nicotine Among Alcohol-Dependent Individuals, by Bankole A. Johnson, DSc, MD, PhD...
Prediction of serotonergic treatment efficacy using age of onset and Type A/B typologies of alcoholismJohn D Roache
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mailstop 7792, San Antonio, Texas 78229, USA
Alcohol Clin Exp Res 32:1502-12. 2008..Randomized participants underwent 11 weeks of treatment with ondansetron (1, 4, or 16 microg/kg twice daily; n = 67, 77, and 71, respectively) or identical placebo (n = 56), plus weekly standardized group cognitive behavioral therapy...
Characterization of a functional polymorphism in the 3' UTR of SLC6A4 and its association with drinking intensityChamindi Seneviratne
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, 1670 Discovery Drive, Charlottesville, VA 22911, USA
Alcohol Clin Exp Res 33:332-9. 2009....
Severity of drinking as a predictor of efficacy of the combination of ondansetron and topiramate in rat models of ethanol consumption and relapseWendy J Lynch
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, 1670 Discovery Drive, Charlottesville, VA 22911, USA
Psychopharmacology (Berl) 217:3-12. 2011..Alcohol dependence is the third leading cause of preventable death in the USA. While single-agent pharmacotherapies have variable efficacy, medication combinations may produce additive effects by modulating multiple neural pathways...
Reductions in and relations between "craving" and drinking in a prospective, open-label trial of ondansetron in adolescents with alcohol dependenceMichael A Dawes
START Center, Division of Alcohol and Drug Addiction, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, The South Texas Addiction Research and Technology Center, San Antonio, TX 78229 3900, USA
Addict Behav 30:1630-7. 2005..These preliminary results suggest that the A-OCDS can be useful as an outcome measure in clinical studies of adolescents with alcohol dependence...
Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjectsBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229 3900, USA
J Clin Psychopharmacol 23:281-93. 2003..More side effects were noted with the combination of medications than with either medication alone. Naltrexone administration significantly increased plasma acamprosate levels...
Development of novel pharmacotherapies for the treatment of alcohol dependence: focus on antiepilepticsBankole A Johnson
Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
Alcohol Clin Exp Res 28:295-301. 2004..DiClemente; (5) Synopsis of promising medications to treat alcoholism, by Robert M. Swift; and (6) New knowledge on the development of antiepileptic medications for the treatment of alcoholism, by Robert J. Malcolm, Jr...
An overview of medications for the treatment of alcohol withdrawal and alcohol dependence with an emphasis on the use of older and newer anticonvulsantsNassima Ait-Daoud
Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
Addict Behav 31:1628-49. 2006..Furthermore, as a class of medication, there appears to be a growing interest in investigating the utility of novel anticonvulsants such as topiramate for the treatment of alcohol dependence...
Impact of motivational changes on drinking outcomes in pharmacobehavioral treatment for alcohol dependenceJennifer K Penberthy
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 35:1694-704. 2011....
Uses of topiramate in the treatment of alcohol dependenceBankole A Johnson
Division of Alcohol and Drug Addiction, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
Expert Rev Neurother 4:751-8. 2004..This drug profile highlights the scientific concepts and clinical evidence in the development of topiramate for treating alcohol dependence...
Ondansetron reduces the craving of biologically predisposed alcoholicsBankole A Johnson
Department of Psychiatry, University of Texas, Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229 3900, USA
Psychopharmacology (Berl) 160:408-13. 2002..Proximate motivational drives such as craving could have determined drinking behavior. We therefore investigated whether ondansetron treatment would reduce alcohol craving significantly among EOA...
A prospective, open-label trial of ondansetron in adolescents with alcohol dependenceMichael A Dawes
START Center, Division of Alcohol and Drug Addiction, Department of Psychiatry, The University of Texas Health Science Center at San Antonio UTHSCSA, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
Addict Behav 30:1077-85. 2005..Findings of decreased drinking underscore the need for future double-blind, placebo-controlled studies in this adolescent population...
An overview of the development of medications including novel anticonvulsants for the treatment of alcohol dependenceBankole A Johnson
Department of Psychiatry, Division of Alcohol and Drug Addiction, The University of Texas Health Science Center at San Antonio, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
Expert Opin Pharmacother 5:1943-55. 2004..Both ondansetron and sertraline appear to have some efficacy in treating different subgroups of alcoholic...
Ondansetron reduces mood disturbance among biologically predisposed, alcohol-dependent individualsBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 78229 3900, USA
Alcohol Clin Exp Res 27:1773-9. 2003....
Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependenceChamindi Seneviratne
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia 22911, USA
Neuropsychopharmacology 34:2442-9. 2009..Additional studies are needed to replicate these results in other samples and to elucidate the mechanism(s) by which these polymorphisms affect NK1R function in the brain...
Topiramate reduces the harm of excessive drinking: implications for public health and primary careJennie Z Ma
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
Addiction 101:1561-8. 2006..Topiramate's potential to decrease the public health consequences of hazardous drinking needs to be established in future long-term studies...
Evaluating readiness and treatment seeking effects in a pharmacotherapy trial for alcohol dependenceJ Kim Penberthy
Center for Addiction Research and Education, Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, Charlottesville, Virginia 22908 0623, USA
Alcohol Clin Exp Res 31:1538-44. 2007..Our goal was to evaluate drinking behavior before initiating a randomized, double-blind pharmacotherapy clinical trial for alcohol dependence...
Preliminary Evidence for cue-induced Alcohol Craving Modulated by Serotonin Transporter Gene Polymorphism rs1042173Nassima Ait-Daoud
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Charlottesville, VA, USA
Front Psychiatry 3:6. 2012....
A multi-level two-part random effects model, with application to an alcohol-dependence studyLei Liu
Division of Biostatistics and Epidemiology, Department of Public Health Sciences, University of Virginia, Charlottesville, VA 22908 0717, USA
Stat Med 27:3528-39. 2008..The model is applied to the analysis of repeated measures of the daily drinking record in a randomized controlled trial of topiramate for alcohol-dependence treatment...
Relative bioavailability of an extemporaneous ondansetron 4-mg capsule formulation versus solutionY W Francis Lam
Department of Pharmacology, University of Texas Health Science Center, San Antonio, Texas 78229-3900, USA
Pharmacotherapy 24:477-81. 2004..The commercially available solution would be a useful alternative formulation for administration of low-dose ondansetron in research and clinical settings...
Role of the serotonergic system in the neurobiology of alcoholism: implications for treatmentBankole A Johnson
University of Virginia Health System, Charlottesville, Virginia 22908 0623, USA
CNS Drugs 18:1105-18. 2004..Such an understanding could enable us to make comfortable predictions as to which alcoholic subtype might respond best to a particular serotonergic agent, which could then be provided...
A pilot evaluation of the safety and tolerability of repeat dose administration of long-acting injectable naltrexone (Vivitrex) in patients with alcohol dependenceBankole A Johnson
University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
Alcohol Clin Exp Res 28:1356-61. 2004..A long-acting injectable naltrexone formulation (Vivitrex) was designed to facilitate patient adherence by providing an extended duration of therapeutic naltrexone over 1 month, thereby eliminating the need for daily dosing...
Effect of topiramate treatment on ethanol consumption in ratsFlorence J Breslin
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, 1670 Discovery Drive, Charlottesville, VA 22911, USA
Psychopharmacology (Berl) 207:529-34. 2010..Results from clinical studies have shown that topiramate effectively reduces alcohol consumption in a population of heavy-drinking alcohol-dependent humans...
Topiramate's effects on cocaine-induced subjective mood, craving and preference for money over drug takingBankole A Johnson
Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, USA
Addict Biol 18:405-16. 2013..Low-dose cocaine might appear to have some enhancement of its stimulant properties in the presence of topiramate's prominent sedative effects...
Pharmacotherapeutic trials in adolescent alcohol use disorders: opportunities and challengesMichael A Dawes
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
Alcohol Alcohol 39:166-77. 2004....
The role of anxiety in predicting drinking behaviourTracy B Sloan
University of Texas Health Science Center, START Center, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229, USA
Alcohol Alcohol 38:360-3. 2003..Those who experienced decreases in anxiety during the treatment reported fewer drinks per day at their last visit compared with those who reported increases in anxiety...
Fine-grain analysis of the treatment effect of topiramate on methamphetamine addiction with latent variable analysisJennie Z Ma
Department of Public Health Sciences, University of Virginia, P O Box 800717, Charlottesville, VA 22908, USA Electronic address
Drug Alcohol Depend 130:45-51. 2013....
Topiramate-induced neuromodulation of cortico-mesolimbic dopamine function: a new vista for the treatment of comorbid alcohol and nicotine dependence?Bankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, South Texas Addiction Research and Technology START Center, San Antonio, TX 78229 3900, USA
Addict Behav 29:1465-79. 2004..Further studies are ongoing to establish and extend topiramate's efficacy in the treatment of each and both disorders...
Progress in the development of topiramate for treating alcohol dependence: from a hypothesis to a proof-of-concept studyBankole A Johnson
Department of Psychiatry, Division of Alcohol and Drug Addiction, The University of Texas Health Science Center at San Antonio, South Texas Addiction Research and Technology START Center, San Antonio, Texas, USA
Alcohol Clin Exp Res 28:1137-44. 2004..This commentary highlights the scientific concepts and clinical evidence for the development of topiramate in the treatment of alcohol dependence...
Current status of carbohydrate deficient transferrin, total serum sialic acid, sialic acid index of apolipoprotein J and serum beta-hexosaminidase as markers for alcohol consumptionMartin A Javors
Department of Psychiatry, The University of Texas HSC, San Antonio, Texas 78229, USA
Addiction 98:45-50. 2003....
The role of serotonergic agents as treatments for alcoholismBankole A Johnson
Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
Drugs Today (Barc) 39:665-72. 2003..This type of understanding could develop our ability to make reasonable predictions as to what alcoholic subtype would respond best to a particular serotonergic agent, which could then be provided...
Genetics of alcoholism using intermediate phenotypesMARY ANNE ENOCH
Laboratory of Neurogenetics, NIAAA, NIH, Bethesda, Maryland 20892 8110, USA
Alcohol Clin Exp Res 27:169-76. 2003..Schuckit; and (4) Pharmacogenomic approaches to alcoholism treatment: toward a hypothesis, by Bankole A. Johnson...
Serotonin-3 receptors in the actions of alcohol, alcohol reinforcement, and alcoholismWilliam J McBride
Indiana University School of Medicine, Indianapolis, Indiana, USA
Alcohol Clin Exp Res 28:257-67. 2004..Rodd and James M. Murphy; and (4) Ondansetron as a treatment for "biological" alcoholism, by John D. Roache and Bankole A. Johnson...
Cost and cost-effectiveness of the COMBINE study in alcohol-dependent patientsGary A Zarkin
RTI International, 3040 Cornwallis Rd, Research Triangle Park, NC 27709, USA
Arch Gen Psychiatry 65:1214-21. 2008..The costs and cost-effectiveness of these combinations are unknown and of interest to clinicians and policy makers...
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: AlcoholismMichael Soyka
Psychiatric Hospital Meiringen, Meiringen, Switzerland
World J Biol Psychiatry 9:6-23. 2008..This first part of the guidelines covers the treatment of alcohol dependence; Part 2 will be devoted to the treatment of drug dependence...
Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trialRaymond F Anton
Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston 29425, USA
JAMA 295:2003-17. 2006..Alcohol dependence treatment may include medications, behavioral therapies, or both. It is unknown how combining these treatments may impact their effectiveness, especially in the context of primary care and other nonspecialty settings...
New weapon to curb smoking: no more excuses to delay treatmentBankole A Johnson
Arch Intern Med 166:1547-50. 2006
Pharmacists' and technicians' perceptions and attitudes toward dispensing buprenorphine/ naloxone to patients with opioid dependenceDennis W Raisch
Veterans Affairs Cooperative Studies Program, Clinical Research Pharmacy Coordinating Center, Albuquerque, NM 87106, USA
J Am Pharm Assoc (2003) 45:23-32. 2005..To assess the perceptions and attitudes of pharmacists and pharmacy technicians involved in an office-based opioid dependence treatment program using buprenorphine/naloxone...
Emerging biomarkers: new directions and clinical applicationsFriedrich M Wurst
Psychiatric University Hospital, Wilhelm Klein Strasse 27, CH 4025 Basel, Switzerland
Alcohol Clin Exp Res 29:465-73. 2005....
