Bankole A Johnson

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. pmc Topiramate's effects on cocaine-induced subjective mood, craving and preference for money over drug taking
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, USA
    Addict Biol 18:405-16. 2013
  2. ncbi A synopsis of the pharmacological rationale, properties and therapeutic effects of depot preparations of naltrexone for treating alcohol dependence
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, PO Box 800623, Charlottesville, VA 22908 0623, USA
    Expert Opin Pharmacother 7:1065-73. 2006
  3. ncbi A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of cocaine dependence
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
    Drug Alcohol Depend 84:256-63. 2006
  4. ncbi Understanding and treating alcohol dependence
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 30:567-84. 2006
  5. ncbi Effects of acute topiramate dosing on methamphetamine-induced subjective mood
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
    Int J Neuropsychopharmacol 10:85-98. 2007
  6. ncbi Recent advances in the development of treatments for alcohol and cocaine dependence: focus on topiramate and other modulators of GABA or glutamate function
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908, USA
    CNS Drugs 19:873-96. 2005
  7. ncbi Challenges and opportunities for medications development in alcoholism: an international perspective on collaborations between academia and industry
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
    Alcohol Clin Exp Res 29:1528-40. 2005
  8. ncbi Use of oral topiramate to promote smoking abstinence among alcohol-dependent smokers: a randomized controlled trial
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
    Arch Intern Med 165:1600-5. 2005
  9. ncbi Effects of isradipine on cocaine-induced changes in cognitive performance in recently abstinent cocaine-dependent individuals
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
    Int J Neuropsychopharmacol 8:549-56. 2005
  10. ncbi Effects of isradipine, a dihydropyridine-class calcium-channel antagonist, on d-methamphetamine's subjective and reinforcing effects
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Int J Neuropsychopharmacol 8:203-13. 2005

Detail Information

Publications75

  1. pmc Topiramate's effects on cocaine-induced subjective mood, craving and preference for money over drug taking
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA, USA
    Addict Biol 18:405-16. 2013
    ..Low-dose cocaine might appear to have some enhancement of its stimulant properties in the presence of topiramate's prominent sedative effects...
  2. ncbi A synopsis of the pharmacological rationale, properties and therapeutic effects of depot preparations of naltrexone for treating alcohol dependence
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, PO Box 800623, Charlottesville, VA 22908 0623, USA
    Expert Opin Pharmacother 7:1065-73. 2006
    ..Naltrel helped reduce relapse and promote abstinence in two samples of alcohol-dependent individuals. Additional efficacy studies are warranted...
  3. ncbi A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of cocaine dependence
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
    Drug Alcohol Depend 84:256-63. 2006
    ..04). These results suggest the possibility of a non-linear dose-response function, with evidence supporting efficacy for the 4.0 mg group...
  4. ncbi Understanding and treating alcohol dependence
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 30:567-84. 2006
    ..Johnson, DSc, MD, PhD; and (5) Differential Effects of Pharmacological Agents on Craving, by Nassima Ait-Daoud, MD...
  5. ncbi Effects of acute topiramate dosing on methamphetamine-induced subjective mood
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
    Int J Neuropsychopharmacol 10:85-98. 2007
    ..Thus, testing chronically administered or higher doses, or both, of topiramate would be necessary to determine conclusively whether or not it can attenuate the positive subjective and reinforcing effects of methamphetamine...
  6. ncbi Recent advances in the development of treatments for alcohol and cocaine dependence: focus on topiramate and other modulators of GABA or glutamate function
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908, USA
    CNS Drugs 19:873-96. 2005
    ....
  7. ncbi Challenges and opportunities for medications development in alcoholism: an international perspective on collaborations between academia and industry
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
    Alcohol Clin Exp Res 29:1528-40. 2005
    ..Swift, MD, PhD; (4) A European Perspective on Medications Development, by Otto M. Lesch, MD, PhD, and (5) A Scandinavian Perspective on Evidence-Based Addiction Treatment, by Mats Berglund, MD...
  8. ncbi Use of oral topiramate to promote smoking abstinence among alcohol-dependent smokers: a randomized controlled trial
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
    Arch Intern Med 165:1600-5. 2005
    ..Herein, we extend that proof-of-concept study by determining whether cigarette-smoking, alcohol-dependent individuals from the earlier study also experienced improved smoking outcomes...
  9. ncbi Effects of isradipine on cocaine-induced changes in cognitive performance in recently abstinent cocaine-dependent individuals
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908 0623, USA
    Int J Neuropsychopharmacol 8:549-56. 2005
    ..Hence, cocaine-taking by cocaine-dependent individuals produces little improvement in cognitive performance and attention in either the presence or absence of isradipine...
  10. ncbi Effects of isradipine, a dihydropyridine-class calcium-channel antagonist, on d-methamphetamine's subjective and reinforcing effects
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Int J Neuropsychopharmacol 8:203-13. 2005
    ..Depending upon conditioning status, isradipine can reduce some methamphetamine-induced positive subjective and reinforcing effects associated with its abuse liability in methamphetamine addicts...
  11. ncbi Pills for speedballing or cocaine dependence
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Lancet 367:1714-6. 2006
  12. pmc Effects of topiramate on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition in recently abstinent methamphetamine-dependent individuals
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
    Prog Neuropsychopharmacol Biol Psychiatry 31:123-30. 2007
    ..Topiramate's complicated cognitive effects among methamphetamine addicts need more comprehensive examination...
  13. pmc Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, PO Box 800623, Charlottesville, VA 22908 0623, USA
    Alcohol Clin Exp Res 35:572-80. 2011
    ..Attention must be paid to the devil in the details...
  14. pmc Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
    Am J Psychiatry 168:265-75. 2011
    ....
  15. pmc Topiramate in the new generation of drugs: efficacy in the treatment of alcoholic patients
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
    Curr Pharm Des 16:2103-12. 2010
    ..Preclinical information that topiramate may have differential effects based on genetic vulnerability opens up the possibility of future methods to optimize treatment...
  16. doi Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
    Arch Intern Med 168:1188-99. 2008
    ..We sought to determine whether topiramate's antidrinking effects are bolstered by improvements in physical and psychosocial well-being...
  17. pmc Can serotonin transporter genotype predict serotonergic function, chronicity, and severity of drinking?
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
    Prog Neuropsychopharmacol Biol Psychiatry 32:209-16. 2008
    ..Thus, 5-HTT expression varies with current and lifetime drinking in L-carriers alone...
  18. ncbi Topiramate for treating alcohol dependence: a randomized controlled trial
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908, USA
    JAMA 298:1641-51. 2007
    ....
  19. pmc Update on neuropharmacological treatments for alcoholism: scientific basis and clinical findings
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
    Biochem Pharmacol 75:34-56. 2008
    ..As neuroscientific research progresses, other promising medications, as well as medication combinations, for treating alcohol dependence continue to be explored...
  20. ncbi A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of methamphetamine dependence
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, VA 22908 0623, USA
    Int J Neuropsychopharmacol 11:1-14. 2008
    ..These findings should be viewed in light of the possibility that a less intensive cognitive behavioural therapy regimen might have yielded more positive results in this initial phase II trial exploring for the efficacy of ondansetron...
  21. pmc Kinetic and cardiovascular effects of acute topiramate dosing among non-treatment-seeking, methamphetamine-dependent individuals
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
    Prog Neuropsychopharmacol Biol Psychiatry 31:455-61. 2007
    ..Larger laboratory studies with chronic dosing regimens are needed to establish whether or not there is a kinetic interaction between topiramate and methamphetamine...
  22. ncbi Acute intravenous low- and high-dose cocaine reduces quantitative global and regional cerebral blood flow in recently abstinent subjects with cocaine use disorder
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
    J Cereb Blood Flow Metab 25:928-36. 2005
    ..Increasingly larger doses of cocaine may be associated with greater risk for ischemic stroke...
  23. ncbi Safety and efficacy of GABAergic medications for treating alcoholism
    Bankole A Johnson
    Department of Psychiatric Medicine, The University of Virginia, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 29:248-54. 2005
    ..Johnson; (5) Evaluating the Risk of Benzodiazepine Prescription to Alcohol-Dependent Individuals, by Domenic A. Ciraulo; and (6) Safety and Efficacy of GABAergic Agents in Treating Alcoholics: Discussion, by Robert M. Swift...
  24. pmc Medication treatment of different types of alcoholism
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, 22908 0623, USA
    Am J Psychiatry 167:630-9. 2010
    ..Brief behavioral interventions that encourage the patient to set goals for a reduction in heavy drinking or abstinence also are part of optimal therapy...
  25. ncbi Kinetic and cardiovascular comparison of immediate-release isradipine and sustained-release isradipine among non-treatment-seeking, cocaine-dependent individuals
    Bankole A Johnson
    South Texas Addiction Research and Technology Center, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
    Prog Neuropsychopharmacol Biol Psychiatry 29:15-20. 2005
    ..The more favorable cardiovascular profile of SR isradipine would, however, make it more appropriate as an investigational medication for the treatment of stimulant dependence and related neurovascular disorders...
  26. ncbi Effects of isradipine on methamphetamine-induced changes in attentional and perceptual-motor skills of cognition
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    Psychopharmacology (Berl) 178:296-302. 2005
    ..Yet, isradipine's effects on cognitive performance in methamphetamine-dependent individuals are not known...
  27. ncbi Isradipine decreases the hemodynamic response of cocaine and methamphetamine results from two human laboratory studies: results from two human laboratory studies
    Bankole A Johnson
    Department of Psychiatric Medicine, University of Virginia, Charlottesville, Virginia 22908 0623, USA
    Am J Hypertens 18:813-22. 2005
    ..We therefore examined, in two separate experiments of similar design conducted contemporaneously, the hemodynamic effects of cocaine or methamphetamine in the presence and absence of isradipine...
  28. ncbi Effects of repeated-dose isradipine on the abuse liability of cocaine
    John D Roache
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, 78229, USA
    Exp Clin Psychopharmacol 13:319-26. 2005
    ..Isradipine enhanced, rather than antagonized, subjective effects, indicating that isradipine does not antagonize cocaine's abuse liability in dependent research volunteers...
  29. pmc Drinking histories in alcohol-use-disordered youth: preliminary findings on relationships to platelet serotonin transporter expression with genotypes of the serotonin transporter
    Michael A Dawes
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    J Stud Alcohol Drugs 70:899-907. 2009
    ..Specifically, we wanted to examine the relationships between the following: platelet 5-HTT and 5-HTT genotype; platelet 5-HTT parameters and age at onset, as well as duration of drinking; and 5-HTT genotype and impulse control...
  30. ncbi Oral topiramate for treatment of alcohol dependence: a randomised controlled trial
    Bankole A Johnson
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, TX 78229 3900, USA
    Lancet 361:1677-85. 2003
    ..We aimed to see whether topiramate was more effective than placebo as a treatment for alcohol dependence...
  31. pmc Platelet serotonin uptake and paroxetine binding among allelic genotypes of the serotonin transporter in alcoholics
    Martin A Javors
    South Texas Addiction Research and Technology START Center, and Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Prog Neuropsychopharmacol Biol Psychiatry 29:7-13. 2005
    ..Our findings in currently drinking alcoholics support the hypothesis that those with the LL genotype of the 5'-HTTLPR region of the 5-HTT gene have reduced 5-HTT function...
  32. ncbi Oral topiramate reduces the consequences of drinking and improves the quality of life of alcohol-dependent individuals: a randomized controlled trial
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 78229 3900, USA
    Arch Gen Psychiatry 61:905-12. 2004
    ..Topiramate, a fructopyranose derivative, was superior to placebo at improving the drinking outcomes of alcohol-dependent individuals...
  33. ncbi Treating smoking dependence in depressed alcoholics
    Nassima Ait-Daoud
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia, USA
    Alcohol Res Health 29:213-20. 2006
    ..Additional treatment strategies targeting dually dependent individuals with comorbid psychiatric disorders, including special populations such as women and adolescents, await further investigation...
  34. ncbi Effects of isradipine on cocaine-induced subjective mood
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229 3900, USA
    J Clin Psychopharmacol 24:180-91. 2004
    ..Also, isradipine-mediated inhibition of mesolimbic DA release may be an ineffective treatment of cocaine dependence...
  35. pmc Can serotonin transporter genotype predict craving in alcoholism?
    Nassima Ait-Daoud
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 33:1329-35. 2009
    ....
  36. ncbi Comorbid alcohol and nicotine dependence: from the biomolecular basis to clinical consequences
    Nassima Ait-Daoud
    Department of Psychiatric Medicine, University of Virginia, Charlottesville 22908 0623, USA
    Alcohol Clin Exp Res 29:1541-9. 2005
    ..Lesch, MD, PhD; and (5) Pharmacotherapy for Promotion of Abstinence from Nicotine Among Alcohol-Dependent Individuals, by Bankole A. Johnson, DSc, MD, PhD...
  37. pmc Association, interaction, and replication analysis of genes encoding serotonin transporter and 5-HT3 receptor subunits A and B in alcohol dependence
    Chamindi Seneviratne
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, 1670 Discovery Drive, Charlottesville, VA, 22911, USA
    Hum Genet 132:1165-76. 2013
    ..007). These findings reveal significant interactive effects among variants in SLC6A4-HTR3A-HTR3B affecting AD. Further studies are needed to confirm these findings and characterize the molecular mechanisms underlying these effects. ..
  38. pmc Characterization of a functional polymorphism in the 3' UTR of SLC6A4 and its association with drinking intensity
    Chamindi Seneviratne
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, 1670 Discovery Drive, Charlottesville, VA 22911, USA
    Alcohol Clin Exp Res 33:332-9. 2009
    ....
  39. doi Severity of drinking as a predictor of efficacy of the combination of ondansetron and topiramate in rat models of ethanol consumption and relapse
    Wendy J Lynch
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, 1670 Discovery Drive, Charlottesville, VA 22911, USA
    Psychopharmacology (Berl) 217:3-12. 2011
    ..Alcohol dependence is the third leading cause of preventable death in the USA. While single-agent pharmacotherapies have variable efficacy, medication combinations may produce additive effects by modulating multiple neural pathways...
  40. pmc Prediction of serotonergic treatment efficacy using age of onset and Type A/B typologies of alcoholism
    John D Roache
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mailstop 7792, San Antonio, Texas 78229, USA
    Alcohol Clin Exp Res 32:1502-12. 2008
    ..Randomized participants underwent 11 weeks of treatment with ondansetron (1, 4, or 16 microg/kg twice daily; n = 67, 77, and 71, respectively) or identical placebo (n = 56), plus weekly standardized group cognitive behavioral therapy...
  41. ncbi An overview of medications for the treatment of alcohol withdrawal and alcohol dependence with an emphasis on the use of older and newer anticonvulsants
    Nassima Ait-Daoud
    Department of Psychiatric Medicine, University of Virginia, P O Box 800623, Charlottesville, VA 22908 0623, USA
    Addict Behav 31:1628-49. 2006
    ..Furthermore, as a class of medication, there appears to be a growing interest in investigating the utility of novel anticonvulsants such as topiramate for the treatment of alcohol dependence...
  42. ncbi Development of novel pharmacotherapies for the treatment of alcohol dependence: focus on antiepileptics
    Bankole A Johnson
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Alcohol Clin Exp Res 28:295-301. 2004
    ..DiClemente; (5) Synopsis of promising medications to treat alcoholism, by Robert M. Swift; and (6) New knowledge on the development of antiepileptic medications for the treatment of alcoholism, by Robert J. Malcolm, Jr...
  43. ncbi Reductions in and relations between "craving" and drinking in a prospective, open-label trial of ondansetron in adolescents with alcohol dependence
    Michael A Dawes
    START Center, Division of Alcohol and Drug Addiction, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, The South Texas Addiction Research and Technology Center, San Antonio, TX 78229 3900, USA
    Addict Behav 30:1630-7. 2005
    ..These preliminary results suggest that the A-OCDS can be useful as an outcome measure in clinical studies of adolescents with alcohol dependence...
  44. ncbi Dose-ranging kinetics and behavioral pharmacology of naltrexone and acamprosate, both alone and combined, in alcohol-dependent subjects
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229 3900, USA
    J Clin Psychopharmacol 23:281-93. 2003
    ..More side effects were noted with the combination of medications than with either medication alone. Naltrexone administration significantly increased plasma acamprosate levels...
  45. doi Impact of motivational changes on drinking outcomes in pharmacobehavioral treatment for alcohol dependence
    Jennifer K Penberthy
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 35:1694-704. 2011
    ....
  46. ncbi Uses of topiramate in the treatment of alcohol dependence
    Bankole A Johnson
    Division of Alcohol and Drug Addiction, Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
    Expert Rev Neurother 4:751-8. 2004
    ..This drug profile highlights the scientific concepts and clinical evidence in the development of topiramate for treating alcohol dependence...
  47. ncbi A prospective, open-label trial of ondansetron in adolescents with alcohol dependence
    Michael A Dawes
    START Center, Division of Alcohol and Drug Addiction, Department of Psychiatry, The University of Texas Health Science Center at San Antonio UTHSCSA, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
    Addict Behav 30:1077-85. 2005
    ..Findings of decreased drinking underscore the need for future double-blind, placebo-controlled studies in this adolescent population...
  48. ncbi An overview of the development of medications including novel anticonvulsants for the treatment of alcohol dependence
    Bankole A Johnson
    Department of Psychiatry, Division of Alcohol and Drug Addiction, The University of Texas Health Science Center at San Antonio, 3939 Medical Drive, Suite 100, San Antonio, TX 78229 3900, USA
    Expert Opin Pharmacother 5:1943-55. 2004
    ..Both ondansetron and sertraline appear to have some efficacy in treating different subgroups of alcoholic...
  49. ncbi Ondansetron reduces the craving of biologically predisposed alcoholics
    Bankole A Johnson
    Department of Psychiatry, University of Texas, Health Science Center at San Antonio, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229 3900, USA
    Psychopharmacology (Berl) 160:408-13. 2002
    ..Proximate motivational drives such as craving could have determined drinking behavior. We therefore investigated whether ondansetron treatment would reduce alcohol craving significantly among EOA...
  50. ncbi Ondansetron reduces mood disturbance among biologically predisposed, alcohol-dependent individuals
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, 78229 3900, USA
    Alcohol Clin Exp Res 27:1773-9. 2003
    ....
  51. pmc Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence
    Chamindi Seneviratne
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville, Virginia 22911, USA
    Neuropsychopharmacology 34:2442-9. 2009
    ..Additional studies are needed to replicate these results in other samples and to elucidate the mechanism(s) by which these polymorphisms affect NK1R function in the brain...
  52. ncbi Evaluating readiness and treatment seeking effects in a pharmacotherapy trial for alcohol dependence
    J Kim Penberthy
    Center for Addiction Research and Education, Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, Charlottesville, Virginia 22908 0623, USA
    Alcohol Clin Exp Res 31:1538-44. 2007
    ..Our goal was to evaluate drinking behavior before initiating a randomized, double-blind pharmacotherapy clinical trial for alcohol dependence...
  53. ncbi Topiramate reduces the harm of excessive drinking: implications for public health and primary care
    Jennie Z Ma
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    Addiction 101:1561-8. 2006
    ....
  54. doi Topiramate for the treatment of cocaine addiction: a randomized clinical trial
    Bankole A Johnson
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia, Charlottesville2now with Department of Psychiatry, University of Maryland School of Medicine, Baltimore
    JAMA Psychiatry 70:1338-46. 2013
    ....
  55. pmc Preliminary Evidence for cue-induced Alcohol Craving Modulated by Serotonin Transporter Gene Polymorphism rs1042173
    Nassima Ait-Daoud
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Charlottesville, VA, USA
    Front Psychiatry 3:6. 2012
    ....
  56. ncbi Role of the serotonergic system in the neurobiology of alcoholism: implications for treatment
    Bankole A Johnson
    University of Virginia Health System, Charlottesville, Virginia 22908 0623, USA
    CNS Drugs 18:1105-18. 2004
    ..Such an understanding could enable us to make comfortable predictions as to which alcoholic subtype might respond best to a particular serotonergic agent, which could then be provided...
  57. doi A multi-level two-part random effects model, with application to an alcohol-dependence study
    Lei Liu
    Division of Biostatistics and Epidemiology, Department of Public Health Sciences, University of Virginia, Charlottesville, VA 22908 0717, USA
    Stat Med 27:3528-39. 2008
    ..The model is applied to the analysis of repeated measures of the daily drinking record in a randomized controlled trial of topiramate for alcohol-dependence treatment...
  58. ncbi Relative bioavailability of an extemporaneous ondansetron 4-mg capsule formulation versus solution
    Y W Francis Lam
    Department of Pharmacology, University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
    Pharmacotherapy 24:477-81. 2004
    ..To compare the relative bioavailability of an extemporaneous ondansetron capsule formulation with that of an identical dose of the commercially available solution formulation...
  59. ncbi A pilot evaluation of the safety and tolerability of repeat dose administration of long-acting injectable naltrexone (Vivitrex) in patients with alcohol dependence
    Bankole A Johnson
    University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Alcohol Clin Exp Res 28:1356-61. 2004
    ..A long-acting injectable naltrexone formulation (Vivitrex) was designed to facilitate patient adherence by providing an extended duration of therapeutic naltrexone over 1 month, thereby eliminating the need for daily dosing...
  60. doi Effect of topiramate treatment on ethanol consumption in rats
    Florence J Breslin
    Department of Psychiatry and Neurobehavioral Sciences, University of Virginia Health System, 1670 Discovery Drive, Charlottesville, VA 22911, USA
    Psychopharmacology (Berl) 207:529-34. 2010
    ..Results from clinical studies have shown that topiramate effectively reduces alcohol consumption in a population of heavy-drinking alcohol-dependent humans...
  61. ncbi Pharmacotherapeutic trials in adolescent alcohol use disorders: opportunities and challenges
    Michael A Dawes
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Alcohol Alcohol 39:166-77. 2004
    ....
  62. ncbi The role of anxiety in predicting drinking behaviour
    Tracy B Sloan
    University of Texas Health Science Center, START Center, 7703 Floyd Curl Drive, Mail Stop 7792, San Antonio, TX 78229, USA
    Alcohol Alcohol 38:360-3. 2003
    ..We investigated whether reduced anxiety predicted improved drinking outcomes over and above age of onset and ondansetron treatment among alcoholics enrolled in a clinical trial...
  63. doi Fine-grain analysis of the treatment effect of topiramate on methamphetamine addiction with latent variable analysis
    Jennie Z Ma
    Department of Public Health Sciences, University of Virginia, PO Box 800717, Charlottesville, VA 22908, USA
    Drug Alcohol Depend 130:45-51. 2013
    ....
  64. ncbi Topiramate-induced neuromodulation of cortico-mesolimbic dopamine function: a new vista for the treatment of comorbid alcohol and nicotine dependence?
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, South Texas Addiction Research and Technology START Center, San Antonio, TX 78229 3900, USA
    Addict Behav 29:1465-79. 2004
    ..Further studies are ongoing to establish and extend topiramate's efficacy in the treatment of each and both disorders...
  65. ncbi Progress in the development of topiramate for treating alcohol dependence: from a hypothesis to a proof-of-concept study
    Bankole A Johnson
    Department of Psychiatry, Division of Alcohol and Drug Addiction, The University of Texas Health Science Center at San Antonio, South Texas Addiction Research and Technology START Center, San Antonio, Texas, USA
    Alcohol Clin Exp Res 28:1137-44. 2004
    ..This commentary highlights the scientific concepts and clinical evidence for the development of topiramate in the treatment of alcohol dependence...
  66. ncbi Current status of carbohydrate deficient transferrin, total serum sialic acid, sialic acid index of apolipoprotein J and serum beta-hexosaminidase as markers for alcohol consumption
    Martin A Javors
    Department of Psychiatry, The University of Texas HSC, San Antonio, Texas 78229, USA
    Addiction 98:45-50. 2003
    ....
  67. ncbi The role of serotonergic agents as treatments for alcoholism
    Bankole A Johnson
    Department of Psychiatry, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229 3900, USA
    Drugs Today (Barc) 39:665-72. 2003
    ..This type of understanding could develop our ability to make reasonable predictions as to what alcoholic subtype would respond best to a particular serotonergic agent, which could then be provided...
  68. pmc Cost and cost-effectiveness of the COMBINE study in alcohol-dependent patients
    Gary A Zarkin
    RTI International, 3040 Cornwallis Rd, Research Triangle Park, NC 27709, USA
    Arch Gen Psychiatry 65:1214-21. 2008
    ..The costs and cost-effectiveness of these combinations are unknown and of interest to clinicians and policy makers...
  69. ncbi Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial
    Raymond F Anton
    Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston 29425, USA
    JAMA 295:2003-17. 2006
    ..Alcohol dependence treatment may include medications, behavioral therapies, or both. It is unknown how combining these treatments may impact their effectiveness, especially in the context of primary care and other nonspecialty settings...
  70. ncbi New weapon to curb smoking: no more excuses to delay treatment
    Bankole A Johnson
    Arch Intern Med 166:1547-50. 2006
  71. ncbi Serotonin-3 receptors in the actions of alcohol, alcohol reinforcement, and alcoholism
    William J McBride
    Indiana University School of Medicine, Indianapolis, Indiana, USA
    Alcohol Clin Exp Res 28:257-67. 2004
    ..Rodd and James M. Murphy; and (4) Ondansetron as a treatment for "biological" alcoholism, by John D. Roache and Bankole A. Johnson...
  72. doi World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism
    Michael Soyka
    Psychiatric Hospital Meiringen, Meiringen, Switzerland
    World J Biol Psychiatry 9:6-23. 2008
    ..This first part of the guidelines covers the treatment of alcohol dependence; Part 2 will be devoted to the treatment of drug dependence...
  73. ncbi Genetics of alcoholism using intermediate phenotypes
    MARY ANNE ENOCH
    Laboratory of Neurogenetics, NIAAA, NIH, Bethesda, Maryland 20892 8110, USA
    Alcohol Clin Exp Res 27:169-76. 2003
    ..Schuckit; and (4) Pharmacogenomic approaches to alcoholism treatment: toward a hypothesis, by Bankole A. Johnson...
  74. ncbi Pharmacists' and technicians' perceptions and attitudes toward dispensing buprenorphine/ naloxone to patients with opioid dependence
    Dennis W Raisch
    Veterans Affairs Cooperative Studies Program, Clinical Research Pharmacy Coordinating Center, Albuquerque, NM 87106, USA
    J Am Pharm Assoc (2003) 45:23-32. 2005
    ..To assess the perceptions and attitudes of pharmacists and pharmacy technicians involved in an office-based opioid dependence treatment program using buprenorphine/naloxone...
  75. ncbi Emerging biomarkers: new directions and clinical applications
    Friedrich M Wurst
    Psychiatric University Hospital, Wilhelm Klein Strasse 27, CH 4025 Basel, Switzerland
    Alcohol Clin Exp Res 29:465-73. 2005
    ....