Research Topics
| B Delia JohnsonSummaryAffiliation: University of Pittsburgh Country: USA Publications
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Detail Information
Publications
Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome EvaluationMichael A Pacanowski
Department of Pharmacy Practice and Center for Pharmacogenomics, University of Florida College of Pharmacy, Gainesville, FL, USA
J Transl Med 6:11. 2008..Adrenergic gene polymorphisms are associated with cardiovascular and metabolic phenotypes. We investigated the influence of adrenergic gene polymorphisms on cardiovascular risk in women with suspected myocardial ischemia...
The relationship of menopausal status and rapid menopausal transition with carotid intima-media thickness progression in women: a report from the Los Angeles Atherosclerosis StudyB Delia Johnson
Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall, 130 De Soto Street, Pittsburgh, Pennsylvania 15241, USA
J Clin Endocrinol Metab 95:4432-40. 2010..However, little information is available about the rapidity of the menopausal transition and its relationship to the development of preclinical cardiovascular disease (CVD)...
Serum amyloid A as a predictor of coronary artery disease and cardiovascular outcome in women: the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE)B Delia Johnson
Graduate School of Public Health, University of Pittsburgh, Parran 127, 130 DeSoto St, Pittsburgh, PA 15261, USA
Circulation 109:726-32. 2004..However, prior studies have yielded inconsistent results, and the independent predictive value of SAA for coronary artery disease (CAD) severity and cardiovascular events remains unclear...
Determination of menopausal status in women: the NHLBI-sponsored Women's Ischemia Syndrome Evaluation (WISE) StudyB Delia Johnson
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Womens Health (Larchmt) 13:872-87. 2004....
Metabolic syndrome modifies the cardiovascular risk associated with angiographic coronary artery disease in women: a report from the Women's Ischemia Syndrome EvaluationOscar C Marroquin
Cardiovascular Institute, University of Pittsburgh, Pittsburgh, PA, USA
Circulation 109:714-21. 2004..Specifically, the metabolic syndrome was found to be a predictor of 4-year cardiovascular risk only when associated with significant angiographic CAD...
Obesity distribution and reproductive hormone levels in women: a report from the NHLBI-sponsored WISE StudyMarian B Olson
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Womens Health (Larchmt) 15:836-42. 2006..The differing levels by general and central obesity may help explain in part observed epidemiological relationships between obesity and disease...
Prognostic value of global MR myocardial perfusion imaging in women with suspected myocardial ischemia and no obstructive coronary disease: results from the NHLBI-sponsored WISE (Women's Ischemia Syndrome Evaluation) studyMark Doyle
Division of Cardiology, CV MRI Center, Allegheny General Hospital, Pittsburgh, Pennsylvania 15212 4772, USA
JACC Cardiovasc Imaging 3:1030-6. 2010....
Persistent chest pain predicts cardiovascular events in women without obstructive coronary artery disease: results from the NIH-NHLBI-sponsored Women's Ischaemia Syndrome Evaluation (WISE) studyB Delia Johnson
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA, USA
Eur Heart J 27:1408-15. 2006..Such women might benefit from additional evaluation and aggressive risk factor modification therapy...
Hypertension, menopause, and coronary artery disease risk in the Women's Ischemia Syndrome Evaluation (WISE) StudyGretchen L Gierach
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Am Coll Cardiol 47:S50-8. 2006..The results suggest that identification of hypertension in premenopausal women dictates additional CAD risk factor assessment and management...
The clinical trial of Women On the Move through Activity and Nutrition (WOMAN) studyLewis H Kuller
Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, PA 15213, United States
Contemp Clin Trials 28:370-81. 2007..Body composition is measured by dual-energy X-ray absorptiometry...
Global inflammation predicts cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) studyKevin E Kip
Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA
Am Heart J 150:900-6. 2005..However, no studies have collectively evaluated how inflammatory markers cluster empirically and relate to angiographic coronary artery disease and CVD events...
Clinical importance of obesity versus the metabolic syndrome in cardiovascular risk in women: a report from the Women's Ischemia Syndrome Evaluation (WISE) studyKevin E Kip
Department of Epidemiology, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA 15261, USA
Circulation 109:706-13. 2004..Both are associated with cardiovascular disease (CVD). However, the contribution of obesity to cardiovascular risk, independent of the presence of the metabolic syndrome, remains controversial...
Prognosis in women with myocardial ischemia in the absence of obstructive coronary disease: results from the National Institutes of Health-National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE)B Delia Johnson
Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA
Circulation 109:2993-9. 2004..Further evaluation into the underlying pathophysiology and possible treatment options for women with evidence of myocardial ischemia but without CAD is indicated...
Phytoestrogens and lipoproteins in womenC Noel Bairey Merz
WISE Coordinating Center, University of Pittsburgh, 127 Parran Hall, Graduate School of Public Health, 130 DeSoto Street, Pittsburgh, Pennsylvania 15261, USA
J Clin Endocrinol Metab 91:2209-13. 2006....
Lifestyle intervention and coronary heart disease risk factor changes over 18 months in postmenopausal women: the Women On the Move through Activity and Nutrition (WOMAN study) clinical trialLewis H Kuller
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA
J Womens Health (Larchmt) 15:962-74. 2006..In this paper, we present the results of changes in risk factors by use of hormone therapy (HT) at 18 months in the Women On the Move through Activity and Nutrition (WOMAN) randomized trial...
Comparison of SWAN and WISE menopausal status classification algorithmsJanet M Johnston
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
J Womens Health (Larchmt) 15:1184-94. 2006..Most epidemiological studies, including the Study of Women's Health Across the Nation (SWAN), classify women based on self-reported bleeding history...
The relationship between physical activity and lipoprotein subclasses in postmenopausal women: the influence of hormone therapyKelley K Pettee
Department of Epidemiology, Internal Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
Menopause 14:115-22. 2007..This study's objective was to determine if the association between physical activity and lipids and lipoprotein subclasses in postmenopausal women varies by hormone therapy (HT) use...
Depression, inflammation, and incident cardiovascular disease in women with suspected coronary ischemia: the National Heart, Lung, and Blood Institute-sponsored WISE studyViola Vaccarino
Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia 30306, USA
J Am Coll Cardiol 50:2044-50. 2007..The purpose of this study was to examine prospectively whether inflammation explains the relationship between depression and cardiovascular disease (CVD)...
Discontinuing hormone replacement therapy: attenuating the effect on CVD risk with lifestyle changesKelley K Pettee
Department of Exercise and Wellness, Arizona State University, 7350 E Unity Drive, Mesa, AZ 85212, USA
Am J Prev Med 32:483-9. 2007..Concern about the potential risks associated with hormone replacement therapy (HRT) has left post-menopausal women and healthcare providers searching for safe and effective means for cardiovascular disease (CVD) risk factor reduction...
Phytoestrogens and coronary microvascular function in women with suspected myocardial ischemia: a report from the Women's Ischemia Syndrome Evaluation (WISE) StudyCarl J Pepine
Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
J Womens Health (Larchmt) 16:481-8. 2007..Accordingly, we investigated the relationship between blood phytoestrogen levels and coronary reactivity in women with suspected myocardial ischemia referred for coronary angiography...
Coronary microvascular reactivity is only partially predicted by atherosclerosis risk factors or coronary artery disease in women evaluated for suspected ischemia: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE)Timothy R Wessel
University of Florida, Division of Cardiovascular Medicine, Gainesville, FL 32610 0277, USA
Clin Cardiol 30:69-74. 2007..Accordingly, the relationship between adenosine-related microvascular coronary reactivity and risk factors in symptomatic women evaluated for suspected ischemia remains uncertain...
Depression, the metabolic syndrome and cardiovascular riskViola Vaccarino
Division of Cardiology, Department of Medicine, Emory University School of Medicine, 1256 Briarcliff Road NE, Suite 1 North, Atlanta, GA 30306, USA
Psychosom Med 70:40-8. 2008..The relationship between depression and the metabolic syndrome is unclear, and whether metabolic syndrome explains the association between depression and cardiovascular disease (CVD) risk is unknown...
Hypoestrogenemia of hypothalamic origin and coronary artery disease in premenopausal women: a report from the NHLBI-sponsored WISE studyC Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Am Coll Cardiol 41:413-9. 2003..We sought to evaluate hypoestrogenemia of hypothalamic origin and its association with angiographic coronary artery disease (CAD) in premenopausal women...
Associations among walking performance, physical activity, and subclinical cardiovascular diseaseKelley K Pettee
Department of Exercise and Wellness, Arizona State Univerisity, Mesa, AZ 85212, USA
Prev Cardiol 10:134-40. 2007..001, respectively). Findings from the current report support the utility of the LDCW to identify women at higher risk for CVD who may be candidates for further cardiovascular testing or intensive lifestyle intervention...
Relationship of physical fitness vs body mass index with coronary artery disease and cardiovascular events in womenTimothy R Wessel
Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL 32610 0277, USA
JAMA 292:1179-87. 2004..Individual contributions of obesity and physical fitness (physical activity and functional capacity) to risk of coronary heart disease in women remain unclear...
Abnormal coronary vasomotion as a prognostic indicator of cardiovascular events in women: results from the National Heart, Lung, and Blood Institute-Sponsored Women's Ischemia Syndrome Evaluation (WISE)Gregory O von Mering
University of Florida College of Medicine, Gainesville, Fla 32610-0277, USA
Circulation 109:722-5. 2004..006). CONCLUSIONS: In women in this study, impaired coronary vasomotor response to acetylcholine was independently linked to adverse cardiovascular outcomes regardless of CAD severity...
The value of estimated functional capacity in estimating outcome: results from the NHBLI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) StudyLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
J Am Coll Cardiol 47:S36-43. 2006..Our objective was to determine the prognostic value of estimated metabolic equivalents (METs) based on self-reported functional capacity by the Duke Activity Status Index (DASI) in symptomatic women...
Cholesterol-lowering medication, cholesterol level, and reproductive hormones in women: the Women's Ischemia Syndrome Evaluation (WISE)C Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
Am J Med 113:723-7. 2002..We also sought to evaluate this association, independent of statin use, particularly among premenopausal women of childbearing age...
Hemoglobin level is an independent predictor for adverse cardiovascular outcomes in women undergoing evaluation for chest pain: results from the National Heart, Lung, and Blood Institute Women's Ischemia Syndrome Evaluation StudyChristopher B Arant
University of Florida College of Medicine, Division of Cardiovascular Medicine, Gainesville, Florida 32610 0277, USA
J Am Coll Cardiol 43:2009-14. 2004..This study was designed to investigate the relationship between hemoglobin level (Hgb) and adverse cardiovascular outcomes in women with suspected ischemia...
Past oral contraceptive use and angiographic coronary artery disease in postmenopausal women: data from the National Heart, Lung, and Blood Institute-sponsored Women's Ischemia Syndrome EvaluationC Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute and Medical Center, Los Angeles, California, USA
Fertil Steril 85:1425-31. 2006..To evaluate past oral contraceptive use and angiographic coronary artery disease in women...
The economic burden of angina in women with suspected ischemic heart disease: results from the National Institutes of Health--National Heart, Lung, and Blood Institute--sponsored Women's Ischemia Syndrome EvaluationLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, Calif, USA
Circulation 114:894-904. 2006..Few data exist regarding the type and intensity of resource consumption in women with chest pain after coronary angiography...
Women's Ischemic Syndrome Evaluation: current status and future research directions: report of the National Heart, Lung and Blood Institute workshop: October 2-4, 2002: Section 1: diagnosis of stable ischemia and ischemic heart diseaseCarl J Pepine
Circulation 109:e44-6. 2004
Impaired coronary vascular reactivity and functional capacity in women: results from the NHLBI Women's Ischemia Syndrome Evaluation (WISE) StudyEileen Handberg
Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida 32610 0277, USA
J Am Coll Cardiol 47:S44-9. 2006..We investigated the relationship between coronary vascular reactivity and functional capacity as assessed from the Duke Activity Status Index (DASI) in a cohort of women evaluated for suspected ischemia...
Migraines, angiographic coronary artery disease and cardiovascular outcomes in womenBina Ahmed
Division of Cardiology, Department of Medicine, Cedars-Sinai Research Institute, Cedars-Sinai Medical Center, Los Angeles, Calif, USA
Am J Med 119:670-5. 2006..We could not support an association between migraines and cardiovascular events or death. Further research studying the common pathophysiology underlying migraines and cardiovascular disease is warranted...
Postmenopausal women with a history of irregular menses and elevated androgen measurements at high risk for worsening cardiovascular event-free survival: results from the National Institutes of Health--National Heart, Lung, and Blood Institute sponsored WLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California 90048, USA
J Clin Endocrinol Metab 93:1276-84. 2008..Women with polycystic ovary syndrome (PCOS) have a greater clustering of cardiac risk factors. However, the link between PCOS and cardiovascular (CV) disease is incompletely described...
Social networks and incident stroke among women with suspected myocardial ischemiaThomas Rutledge
Department of Psychiatry, VA San Diego Healthcare System, University of California, San Diego, CA 92161, USA
Psychosom Med 70:282-7. 2008..Social networks are an independent predictor of all-cause and cardiovascular mortality, but their relationship with stroke events in at-risk populations is largely unknown...
Diabetes mellitus, hypothalamic hypoestrogenemia, and coronary artery disease in premenopausal women (from the National Heart, Lung, and Blood Institute sponsored WISE study)Bina Ahmed
Department of Medicine, Division of Cardiology, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
Am J Cardiol 102:150-4. 2008..The presence of both DM and HHE predicted a greater burden of angiographic CAD. Prospective research is warranted to better understand causal relations between DM, endogenous hormones, and MACE in premenopausal women...
Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular corC Noel Bairey Merz
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Am Coll Cardiol 47:S21-9. 2006..Additionally, innovative cardiovascular imaging techniques will be discussed. Finally, we identify critical areas of further inquiry needed to advance this new gender-specific IHD understanding into improved outcomes for women...
Insights from the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation (WISE) Study: Part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategiesLeslee J Shaw
Division of Cardiology, Department of Medicine, Cedars Sinai Research Institute, Cedars Sinai Medical Center, Los Angeles, California, USA
J Am Coll Cardiol 47:S4-S20. 2006....
