Research Topics
| B A JohnsonSummaryAffiliation: University of California Country: USA Publications
| Collaborators
|
Detail Information
Publications
Odorants with multiple oxygen-containing functional groups and other odorants with high water solubility preferentially activate posterior olfactory bulb glomeruliBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 502:468-82. 2007....
Spatial coding of odorant features in the glomerular layer of the rat olfactory bulbB A Johnson
Department of Psychobiology, University of California, Irvine 92697 4550, USA
J Comp Neurol 393:457-71. 1998..Thus, molecular features appear to be encoded spatially in the glomerular layer, and the identity of the odorant may be determined by a subsequent decoding of the combination of molecular features represented in the glomerular layer...- Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulbBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697 4550, USA
J Comp Neurol 483:192-204. 2005..These results help to define further the specificities of glomeruli within previously described glomerular modules, and they show that functional group position can be an important feature in encoding an odorant molecule... - Interactions between odorant functional group and hydrocarbon structure influence activity in glomerular response modules in the rat olfactory bulbBrett A Johnson
Department of Neurobiology and Behavior, University of California at Irvine, Irvine, CA 92697 4550, USA
J Comp Neurol 483:205-16. 2005.... - Local and global chemotopic organization: general features of the glomerular representations of aliphatic odorants differing in carbon numberBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 480:234-49. 2004..Thus, global chemotopy and local modular chemotopy appear to be fundamental principles underlying the representation of odorants differing in carbon chain length... - Effects of double and triple bonds on the spatial representations of odorants in the rat olfactory bulbBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 500:720-33. 2007.... - Chemotopic odorant coding in a mammalian olfactory systemBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4550, USA
J Comp Neurol 503:1-34. 2007..A critical analysis suggests that alternative coding mechanisms for odor quality, such as those based on temporal patterns of responses, enjoy little experimental support... - Functional mapping of the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural featuresBrett A Johnson
Department of Neurobiology and Behavior, University of California, 2205 McGaugh Hall, Irvine, CA 92697 4550, USA
J Comp Neurol 449:180-94. 2002.... 
Spatial representations of odorants in olfactory bulbs of rats and mice: similarities and differences in chemotopic organizationBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 514:658-73. 2009..We conclude that clustering responses to shared odorant features may be a general strategy for odor coding but that the specific locations of high-activity domains may be unique to a species...- Odorant molecular length: one aspect of the olfactory codeB A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
J Comp Neurol 426:330-8. 2000..These data suggest that posterior portions of the bulb may encode specific steric features of odorant molecules and that some odorant features may have an inherent or acquired greater representation than do others... - Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentrationB A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
J Comp Neurol 422:496-509. 2000.... - Multidimensional chemotopic responses to n-aliphatic acid odorants in the rat olfactory bulbB A Johnson
School of Biological Sciences, University of California, Irvine 92697 4550, USA
J Comp Neurol 409:529-48. 1999..They also support the notion that analyses of the spatial relationships among odorant responses in the olfactory bulb can demonstrate aspects of the mechanism for odor chemical coding... - Differential specificity in the glomerular response profiles for alicyclic, bicyclic, and heterocyclic odorantsBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 499:1-16. 2006..We conclude that, whereas some of the novel cyclic structures indeed were represented by unique patterns in the rat bulb, other unique structures were poorly represented, even when they evoked intense and unique odors in humans... - Prolonged stimulus exposure reveals prolonged neurobehavioral response patternsBrett A Johnson
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 518:1617-29. 2010..Given these findings, it seems important to consider the possibility that prolonged exposure to other sensory stimuli will reveal more realistic neural response patterns... - Perceptual correlates of neural representations evoked by odorant enantiomersC Linster
Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853, USA
J Neurosci 21:9837-43. 2001.... - Glomerular activity patterns evoked by natural odor objects in the rat olfactory bulb are related to patterns evoked by major odorant componentsBrett A Johnson
Department of Neurobiology and Behavior, University of California Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 518:1542-55. 2010..These data suggest the possibility of mixture response interactions and provide a foundation for understanding the neural coding of natural odor stimuli... - Spontaneous versus reinforced olfactory discriminationsChristiane Linster
Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853, USA
J Neurosci 22:6842-5. 2002..At the same time, the major differences in glomerular responses appear to serve as the normal basis for spontaneous odor discrimination... - Chemotopic representations of aromatic odorants in the rat olfactory bulbHaleh Farahbod
Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
J Comp Neurol 497:350-66. 2006..These relationships between the structure of aromatic compounds and their spatial representation in the bulb are contrasted with our previous findings with aliphatic odorants... - Is there a space-time continuum in olfaction?Michael Leon
Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697 4550, USA
Cell Mol Life Sci 66:2135-50. 2009..We review the data supporting these ideas, and we discuss the research perspectives that could help to reveal the mechanisms by which odorants become perceptions... - Long hydrocarbon chains serve as unique molecular features recognized by ventral glomeruli of the rat olfactory bulbSabrina L Ho
Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
J Comp Neurol 498:16-30. 2006..We found a close and predictable relationship among the molecular properties of odorants, their induced neural activity, and their perceptual similarities... - Olfactory coding in the mammalian olfactory bulbMichael Leon
Department of Neurobiology and Behavior, University of California, Room 2205 MH, Irvine, CA 92697 4550, USA
Brain Res Brain Res Rev 42:23-32. 2003..These rules have allowed us to predict where previously unmapped molecules would be represented and how differences in molecular representations affect olfactory perceptions... - Broad activation of the glomerular layer enhances subsequent olfactory responsesCynthia C Woo
Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4550, USA
Chem Senses 32:51-5. 2007..Our results indicate that early experience with multiple odorants results in increased responsiveness both to previously experienced odorants and to novel odorants that stimulate previously activated regions of the bulb... - Differential responses to branched and unsaturated aliphatic hydrocarbons in the rat olfactory systemSabrina L Ho
Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
J Comp Neurol 499:519-32. 2006..The results further suggest that the olfactory system does not respond equally to all aspects of odorant chemistry, functioning as a specific, rather than a general, chemical analysis system... - Relational representation in the olfactory systemThomas A Cleland
Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA
Proc Natl Acad Sci U S A 104:1953-8. 2007..We show that global feed-forward normalization in a sensory system is behaviorally relevant, and that a center-surround neural architecture does not necessarily imply center-surround function... - Predicting odorant quality perceptions from multidimensional scaling of olfactory bulb glomerular activity patternsSteven L Youngentob
Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
Behav Neurosci 120:1337-45. 2006..These results strongly support the relevance of global spatial patterns in the olfactory bulb to the encoding of odor quality... - Spatiotemporal distribution of the insulin-like growth factor receptor in the rat olfactory bulbCarina C Ferrari
Department of Cell Biology, Neurobiology and Anatomy, University Cincinnati College of Medicine, Cincinnati, Ohio 45267-0521, USA
Neurochem Res 28:29-43. 2003..IGF-I may play a role in glomerular synaptogenesis and/or plasticity, possibly contributing to development of coding patterns for odor detection or identification...