B A Johnson

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Odorants with multiple oxygen-containing functional groups and other odorants with high water solubility preferentially activate posterior olfactory bulb glomeruli
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 502:468-82. 2007
  2. ncbi request reprint Spatial coding of odorant features in the glomerular layer of the rat olfactory bulb
    B A Johnson
    Department of Psychobiology, University of California, Irvine 92697 4550, USA
    J Comp Neurol 393:457-71. 1998
  3. pmc Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulb
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697 4550, USA
    J Comp Neurol 483:192-204. 2005
  4. pmc Interactions between odorant functional group and hydrocarbon structure influence activity in glomerular response modules in the rat olfactory bulb
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California at Irvine, Irvine, CA 92697 4550, USA
    J Comp Neurol 483:205-16. 2005
  5. ncbi request reprint Local and global chemotopic organization: general features of the glomerular representations of aliphatic odorants differing in carbon number
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 480:234-49. 2004
  6. pmc Effects of double and triple bonds on the spatial representations of odorants in the rat olfactory bulb
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 500:720-33. 2007
  7. pmc Chemotopic odorant coding in a mammalian olfactory system
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4550, USA
    J Comp Neurol 503:1-34. 2007
  8. ncbi request reprint Functional mapping of the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural features
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, 2205 McGaugh Hall, Irvine, CA 92697 4550, USA
    J Comp Neurol 449:180-94. 2002
  9. doi request reprint Spatial representations of odorants in olfactory bulbs of rats and mice: similarities and differences in chemotopic organization
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 514:658-73. 2009
  10. ncbi request reprint Odorant molecular length: one aspect of the olfactory code
    B A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
    J Comp Neurol 426:330-8. 2000

Detail Information

Publications26

  1. pmc Odorants with multiple oxygen-containing functional groups and other odorants with high water solubility preferentially activate posterior olfactory bulb glomeruli
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 502:468-82. 2007
    ....
  2. ncbi request reprint Spatial coding of odorant features in the glomerular layer of the rat olfactory bulb
    B A Johnson
    Department of Psychobiology, University of California, Irvine 92697 4550, USA
    J Comp Neurol 393:457-71. 1998
    ..Thus, molecular features appear to be encoded spatially in the glomerular layer, and the identity of the odorant may be determined by a subsequent decoding of the combination of molecular features represented in the glomerular layer...
  3. pmc Effects of functional group position on spatial representations of aliphatic odorants in the rat olfactory bulb
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA 92697 4550, USA
    J Comp Neurol 483:192-204. 2005
    ..These results help to define further the specificities of glomeruli within previously described glomerular modules, and they show that functional group position can be an important feature in encoding an odorant molecule...
  4. pmc Interactions between odorant functional group and hydrocarbon structure influence activity in glomerular response modules in the rat olfactory bulb
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California at Irvine, Irvine, CA 92697 4550, USA
    J Comp Neurol 483:205-16. 2005
    ....
  5. ncbi request reprint Local and global chemotopic organization: general features of the glomerular representations of aliphatic odorants differing in carbon number
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 480:234-49. 2004
    ..Thus, global chemotopy and local modular chemotopy appear to be fundamental principles underlying the representation of odorants differing in carbon chain length...
  6. pmc Effects of double and triple bonds on the spatial representations of odorants in the rat olfactory bulb
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 500:720-33. 2007
    ....
  7. pmc Chemotopic odorant coding in a mammalian olfactory system
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4550, USA
    J Comp Neurol 503:1-34. 2007
    ..A critical analysis suggests that alternative coding mechanisms for odor quality, such as those based on temporal patterns of responses, enjoy little experimental support...
  8. ncbi request reprint Functional mapping of the rat olfactory bulb using diverse odorants reveals modular responses to functional groups and hydrocarbon structural features
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, 2205 McGaugh Hall, Irvine, CA 92697 4550, USA
    J Comp Neurol 449:180-94. 2002
    ....
  9. doi request reprint Spatial representations of odorants in olfactory bulbs of rats and mice: similarities and differences in chemotopic organization
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 514:658-73. 2009
    ..We conclude that clustering responses to shared odorant features may be a general strategy for odor coding but that the specific locations of high-activity domains may be unique to a species...
  10. ncbi request reprint Odorant molecular length: one aspect of the olfactory code
    B A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
    J Comp Neurol 426:330-8. 2000
    ..These data suggest that posterior portions of the bulb may encode specific steric features of odorant molecules and that some odorant features may have an inherent or acquired greater representation than do others...
  11. ncbi request reprint Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration
    B A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
    J Comp Neurol 422:496-509. 2000
    ....
  12. ncbi request reprint Multidimensional chemotopic responses to n-aliphatic acid odorants in the rat olfactory bulb
    B A Johnson
    School of Biological Sciences, University of California, Irvine 92697 4550, USA
    J Comp Neurol 409:529-48. 1999
    ..They also support the notion that analyses of the spatial relationships among odorant responses in the olfactory bulb can demonstrate aspects of the mechanism for odor chemical coding...
  13. pmc Differential specificity in the glomerular response profiles for alicyclic, bicyclic, and heterocyclic odorants
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 499:1-16. 2006
    ..We conclude that, whereas some of the novel cyclic structures indeed were represented by unique patterns in the rat bulb, other unique structures were poorly represented, even when they evoked intense and unique odors in humans...
  14. doi request reprint Prolonged stimulus exposure reveals prolonged neurobehavioral response patterns
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 518:1617-29. 2010
    ..Given these findings, it seems important to consider the possibility that prolonged exposure to other sensory stimuli will reveal more realistic neural response patterns...
  15. ncbi request reprint Perceptual correlates of neural representations evoked by odorant enantiomers
    C Linster
    Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853, USA
    J Neurosci 21:9837-43. 2001
    ....
  16. doi request reprint Glomerular activity patterns evoked by natural odor objects in the rat olfactory bulb are related to patterns evoked by major odorant components
    Brett A Johnson
    Department of Neurobiology and Behavior, University of California Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 518:1542-55. 2010
    ..These data suggest the possibility of mixture response interactions and provide a foundation for understanding the neural coding of natural odor stimuli...
  17. ncbi request reprint Spontaneous versus reinforced olfactory discriminations
    Christiane Linster
    Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853, USA
    J Neurosci 22:6842-5. 2002
    ..At the same time, the major differences in glomerular responses appear to serve as the normal basis for spontaneous odor discrimination...
  18. pmc Chemotopic representations of aromatic odorants in the rat olfactory bulb
    Haleh Farahbod
    Department of Neurobiology and Behavior, University of California, Irvine, Irvine, California 92697 4550, USA
    J Comp Neurol 497:350-66. 2006
    ..These relationships between the structure of aromatic compounds and their spatial representation in the bulb are contrasted with our previous findings with aliphatic odorants...
  19. pmc Is there a space-time continuum in olfaction?
    Michael Leon
    Department of Neurobiology and Behavior, University of California Irvine, Irvine, CA 92697 4550, USA
    Cell Mol Life Sci 66:2135-50. 2009
    ..We review the data supporting these ideas, and we discuss the research perspectives that could help to reveal the mechanisms by which odorants become perceptions...
  20. pmc Long hydrocarbon chains serve as unique molecular features recognized by ventral glomeruli of the rat olfactory bulb
    Sabrina L Ho
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
    J Comp Neurol 498:16-30. 2006
    ..We found a close and predictable relationship among the molecular properties of odorants, their induced neural activity, and their perceptual similarities...
  21. ncbi request reprint Olfactory coding in the mammalian olfactory bulb
    Michael Leon
    Department of Neurobiology and Behavior, University of California, Room 2205 MH, Irvine, CA 92697 4550, USA
    Brain Res Brain Res Rev 42:23-32. 2003
    ..These rules have allowed us to predict where previously unmapped molecules would be represented and how differences in molecular representations affect olfactory perceptions...
  22. pmc Broad activation of the glomerular layer enhances subsequent olfactory responses
    Cynthia C Woo
    Department of Neurobiology and Behavior, University of California, Irvine, CA 92697 4550, USA
    Chem Senses 32:51-5. 2007
    ..Our results indicate that early experience with multiple odorants results in increased responsiveness both to previously experienced odorants and to novel odorants that stimulate previously activated regions of the bulb...
  23. pmc Differential responses to branched and unsaturated aliphatic hydrocarbons in the rat olfactory system
    Sabrina L Ho
    Department of Neurobiology and Behavior, University of California, Irvine, California 92697 4550, USA
    J Comp Neurol 499:519-32. 2006
    ..The results further suggest that the olfactory system does not respond equally to all aspects of odorant chemistry, functioning as a specific, rather than a general, chemical analysis system...
  24. pmc Relational representation in the olfactory system
    Thomas A Cleland
    Department of Neurobiology and Behavior, Cornell University, Ithaca, NY 14853, USA
    Proc Natl Acad Sci U S A 104:1953-8. 2007
    ..We show that global feed-forward normalization in a sensory system is behaviorally relevant, and that a center-surround neural architecture does not necessarily imply center-surround function...
  25. pmc Predicting odorant quality perceptions from multidimensional scaling of olfactory bulb glomerular activity patterns
    Steven L Youngentob
    Department of Neuroscience and Physiology, State University of New York, Upstate Medical University, Syracuse, NY 13210, USA
    Behav Neurosci 120:1337-45. 2006
    ..These results strongly support the relevance of global spatial patterns in the olfactory bulb to the encoding of odor quality...
  26. ncbi request reprint Spatiotemporal distribution of the insulin-like growth factor receptor in the rat olfactory bulb
    Carina C Ferrari
    Department of Cell Biology, Neurobiology and Anatomy, University Cincinnati College of Medicine, Cincinnati, Ohio 45267 0521, USA
    Neurochem Res 28:29-43. 2003
    ..IGF-I may play a role in glomerular synaptogenesis and/or plasticity, possibly contributing to development of coding patterns for odor detection or identification...