Ranjit John

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi Lessons learned from experience with over 100 consecutive HeartMate II left ventricular assist devices
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, 420 Delaware St SE, MMC 207, Minneapolis, MN 55455, USA
    Ann Thorac Surg 92:1593-9; discussion 1599-600. 2011
  2. ncbi Low thromboembolic risk for patients with the Heartmate II left ventricular assist device
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minn 55455, USA
    J Thorac Cardiovasc Surg 136:1318-23. 2008
  3. ncbi Effects on pre- and posttransplant pulmonary hemodynamics in patients with continuous-flow left ventricular assist devices
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minn 55455, USA
    J Thorac Cardiovasc Surg 140:447-52. 2010
  4. ncbi Donor management and selection for heart transplantation
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    Semin Thorac Cardiovasc Surg 16:364-9. 2004
  5. ncbi The biological basis of thrombosis and bleeding in patients with ventricular assist devices
    Ranjit John
    Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    J Cardiovasc Transl Res 2:63-70. 2009
  6. ncbi Perioperative outcomes of cardiac surgery in kidney and kidney-pancreas transplant recipients
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minn 55455, USA
    J Thorac Cardiovasc Surg 133:1212-9. 2007
  7. ncbi Experience with the Levitronix CentriMag circulatory support system as a bridge to decision in patients with refractory acute cardiogenic shock and multisystem organ failure
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minn, USA
    J Thorac Cardiovasc Surg 134:351-8. 2007
  8. ncbi Physiologic and pathologic changes in patients with continuous-flow ventricular assist devices
    Ranjit John
    Department of Surgery, University of Minnesota, Minneapolis, MN, USA
    J Cardiovasc Transl Res 2:154-8. 2009
  9. ncbi Activation of endothelial and coagulation systems in left ventricular assist device recipients
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Ann Thorac Surg 88:1171-9. 2009
  10. ncbi Current axial-flow devices--the HeartMate II and Jarvik 2000 left ventricular assist devices
    Ranjit John
    Department of Surgery, Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Semin Thorac Cardiovasc Surg 20:264-72. 2008

Detail Information

Publications53

  1. ncbi Lessons learned from experience with over 100 consecutive HeartMate II left ventricular assist devices
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, 420 Delaware St SE, MMC 207, Minneapolis, MN 55455, USA
    Ann Thorac Surg 92:1593-9; discussion 1599-600. 2011
    ..The aim of this study is to report the outcomes in patients receiving the HeartMate II LVAD at a single center and review the lessons learned from this experience...
  2. ncbi Low thromboembolic risk for patients with the Heartmate II left ventricular assist device
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minn 55455, USA
    J Thorac Cardiovasc Surg 136:1318-23. 2008
    ..In our study, we investigated whether the HeartMate II left ventricular assist device is associated with a similarly low thromboembolic risk as the HeartMate XVE...
  3. ncbi Effects on pre- and posttransplant pulmonary hemodynamics in patients with continuous-flow left ventricular assist devices
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minn 55455, USA
    J Thorac Cardiovasc Surg 140:447-52. 2010
    ....
  4. ncbi Donor management and selection for heart transplantation
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    Semin Thorac Cardiovasc Surg 16:364-9. 2004
    ....
  5. ncbi The biological basis of thrombosis and bleeding in patients with ventricular assist devices
    Ranjit John
    Department of Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    J Cardiovasc Transl Res 2:63-70. 2009
    ....
  6. ncbi Perioperative outcomes of cardiac surgery in kidney and kidney-pancreas transplant recipients
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minn 55455, USA
    J Thorac Cardiovasc Surg 133:1212-9. 2007
    ..We performed a retrospective study of kidney transplant recipients who underwent cardiac surgery over the past 10 years at our institution with an emphasis on evaluating postoperative outcomes...
  7. ncbi Experience with the Levitronix CentriMag circulatory support system as a bridge to decision in patients with refractory acute cardiogenic shock and multisystem organ failure
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minn, USA
    J Thorac Cardiovasc Surg 134:351-8. 2007
    ..We review our experience with the use of the CentriMag (Levitronix LLC, Waltham, Mass) circulatory support system in such patients whose neurologic status was uncertain...
  8. ncbi Physiologic and pathologic changes in patients with continuous-flow ventricular assist devices
    Ranjit John
    Department of Surgery, University of Minnesota, Minneapolis, MN, USA
    J Cardiovasc Transl Res 2:154-8. 2009
    ..This manuscript overviews the physiologic and pathologic effects that are associated with continuous-flow pumps and their unique management issues and complications...
  9. ncbi Activation of endothelial and coagulation systems in left ventricular assist device recipients
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Ann Thorac Surg 88:1171-9. 2009
    ..To better understand hemorrhagic and thromboembolic complications that currently limit the use of such devices, we studied the endothelial and coagulation system changes in LVAD recipients with time...
  10. ncbi Current axial-flow devices--the HeartMate II and Jarvik 2000 left ventricular assist devices
    Ranjit John
    Department of Surgery, Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Semin Thorac Cardiovasc Surg 20:264-72. 2008
    ..Different strategies are required to optimize outcomes with these newer devices...
  11. ncbi Improved survival and decreasing incidence of adverse events with the HeartMate II left ventricular assist device as bridge-to-transplant therapy
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Ann Thorac Surg 86:1227-34; discussion 1234-5. 2008
    ..Smaller, more durable, continuous flow devices such as the HeartMate II LVAD are increasingly being used. The aim of this study is to report our single-center experience with this device as bridge-to-transplant therapy...
  12. ncbi Outcomes of a multicenter trial of the Levitronix CentriMag ventricular assist system for short-term circulatory support
    Ranjit John
    University of Minnesota Medical Center, Minneapolis, Minn, USA
    J Thorac Cardiovasc Surg 141:932-9. 2011
    ..This multi-institutional study evaluated safety, effectiveness, and outcomes of the CentriMag in patients with cardiogenic shock...
  13. ncbi Aortic valve pathophysiology during left ventricular assist device support
    Ranjit John
    Division of Cardiothoracic Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Heart Lung Transplant 29:1321-9. 2010
    ..The basis for structural changes leading to valve pathophysiology during and after LVAD placement will be described, providing a basis for improved clinical understanding and new strategies to prevent these conditions...
  14. ncbi Right ventricular failure--a continuing problem in patients with left ventricular assist device support
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, MN 55455, USA
    J Cardiovasc Transl Res 3:604-11. 2010
    ..However, the lower incidence of RV failure following LVAD in the current era is encouraging, suggesting a favorable relationship between RV unloading and function, and continuous-flow physiology...
  15. ncbi Continuous flow left ventricular assist device outcomes in commercial use compared with the prior clinical trial
    Ranjit John
    University of Minnesota, Minneapolis, MN, USA
    Ann Thorac Surg 92:1406-13; discussion 1413. 2011
    ..The purpose of this analysis was to determine changes in posttrial outcomes in widespread commercial use since the clinical trial...
  16. ncbi Post-cardiac transplant survival after support with a continuous-flow left ventricular assist device: impact of duration of left ventricular assist device support and other variables
    Ranjit John
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minn 55455, USA
    J Thorac Cardiovasc Surg 140:174-81. 2010
    ..We sought to determine factors related to posttransplant survival in patients supported with continuous-flow LVADs...
  17. ncbi Should heart transplantation be considered as a treatment option for patients aged 70 years and older?
    Jeffrey A Morgan
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Thorac Cardiovasc Surg 127:1817-9. 2004
  18. ncbi Outcomes in cardiac transplant recipients using allografts from older donors versus mortality on the transplant waiting list; Implications for donor selection criteria
    Katherine Lietz
    Division of Cardiothoracic Surgery, Columbia Presbyterian Medical Center, Columbia University, New York, New York 10032, USA
    J Am Coll Cardiol 43:1553-61. 2004
    ....
  19. ncbi Low thromboembolism and pump thrombosis with the HeartMate II left ventricular assist device: analysis of outpatient anti-coagulation
    Andrew J Boyle
    Division of Cardiology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Heart Lung Transplant 28:881-7. 2009
    ..We evaluated the risk of thromboembolism and hemorrhage related to the degree of anti-coagulation as reflected by the international normalized ratio (INR)...
  20. ncbi Long-term results of cardiac transplantation in patients 65 years of age and older: a comparative analysis
    Jeffrey A Morgan
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    Ann Thorac Surg 76:1982-7. 2003
    ..Advanced age is viewed by some transplant centers as a contraindication for heart transplantation secondary to concerns regarding decreased survival...
  21. ncbi Successful outcome with extended allograft ischemic time in pediatric heart transplantation
    Jeffrey A Morgan
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, 177 Fort Washington Avenue, New York, NY 10032, USA
    J Heart Lung Transplant 24:58-62. 2005
    ..The focus of this study was to examine the effect of extended DIT on mortality after pediatric heart transplantation...
  22. ncbi Use of a continuous-flow device in patients awaiting heart transplantation
    Leslie W Miller
    University of Minnesota, Minneapolis, USA
    N Engl J Med 357:885-96. 2007
    ..Continuous-flow pumps are newer types of left ventricular assist devices developed to overcome some of these limitations...
  23. ncbi Bridging to transplant with the HeartMate left ventricular assist device: The Columbia Presbyterian 12-year experience
    Jeffrey A Morgan
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    J Thorac Cardiovasc Surg 127:1309-16. 2004
    ..This is likely due to a combination of better patient selection, improvements in clinical practice, and evolution in device design...
  24. ncbi Heart transplantation in diabetic recipients: a decade review of 161 patients at Columbia Presbyterian
    Jeffrey A Morgan
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA
    J Thorac Cardiovasc Surg 127:1486-92. 2004
    ..We evaluated our experience with diabetic recipients over the last 10 years...
  25. ncbi Effects of centrifugal, axial, and pulsatile left ventricular assist device support on end-organ function in heart failure patients
    Forum Kamdar
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Heart Lung Transplant 28:352-9. 2009
    ..This study investigated whether centrifugal devices have similar effects on end-organ function...
  26. ncbi Prolonged donor ischemic time does not adversely affect long-term survival in adult patients undergoing cardiac transplantation
    Jeffrey A Morgan
    Department of Surgery, Division of Cardiothoracic Surgery, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    J Thorac Cardiovasc Surg 126:1624-33. 2003
    ..Although several studies have evaluated the effects of prolonged donor ischemic times on short-term survival and graft function, few have addressed concerns regarding long-term survival...
  27. ncbi Immunoglobulin M-to-immunoglobulin G anti-human leukocyte antigen class II antibody switching in cardiac transplant recipients is associated with an increased risk of cellular rejection and coronary artery disease
    Katherine Lietz
    Division of Cardiothoracic Surgery, Columbia-Persbyterian Medical Center, New York, NY 10032, USA
    Circulation 112:2468-76. 2005
    ....
  28. ncbi Effects of the HeartMate II continuous-flow left ventricular assist device on right ventricular function
    Sangjin Lee
    Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, Minnesota, USA
    J Heart Lung Transplant 29:209-15. 2010
    ..This study evaluated the incidence of RV failure, alterations in RV function, severity of tricuspid regurgitation (TR), and cardiac hemodynamics after HMII implantation...
  29. ncbi Low operative mortality with implantation of a continuous-flow left ventricular assist device and impact of concurrent cardiac procedures
    Jay D Pal
    Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
    Circulation 120:S215-9. 2009
    ..The objective of this study was to determine the impact of concurrent cardiac procedures (CCP) on patient outcomes after HeartMate II (HMII) left ventricular assist device implantation...
  30. ncbi Intermittent antegrade cardioplegia: isolated heart preservation with the Asporto heart preservation device
    Andrew L Rivard
    University of Minnesota, Minneapolis, USA
    Prog Transplant 18:127-33. 2008
    ..The global myocardial ischemia causes a cascade of oxygen radical formation that cumulates in an elevation in hydrogen ions (decrease in pH), irreversible cellular injury, and potential microvascular changes in perfusion...
  31. ncbi Comparison of risk scores to estimate perioperative mortality in aortic valve replacement surgery
    Jagroop Basraon
    Division of Cardiology, Veterans Administration Medical Center and University of Minnesota, Minneapolis, Minnesota 55417, USA
    Ann Thorac Surg 92:535-40. 2011
    ..We compared the accuracy of The Society of Thoracic Surgeons (STS) risk score, the European System for Cardiac Risk Evaluation (EuroSCORE), and the Veterans Administration (VA) risk score in predicting perioperative mortality after AVR...
  32. ncbi Effects of pulsatile- and continuous-flow left ventricular assist devices on left ventricular unloading
    Santiago Garcia
    Department of Cardiology, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Heart Lung Transplant 27:261-7. 2008
    ..The aim of this investigation was to compare the effects of pulsatile- vs continuous-flow LVADs on left ventricular reverse remodeling and hemodynamic indices...
  33. ncbi Carotid endarterectomy prior to ventricular assist device placement
    Jonathan D McCue
    Department of Surgery, University of Minnesota, Minneapolis, MN, USA
    Ann Vasc Surg 21:813-5. 2007
    ..We present the first report in the literature of CEA in a patient with severe carotid disease prior to elective VAD placement...
  34. ncbi Is severe right ventricular failure in left ventricular assist device recipients a risk factor for unsuccessful bridging to transplant and post-transplant mortality
    Jeffrey A Morgan
    Department of Surgery, Division of Cardiothoracic Surgery, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Ann Thorac Surg 77:859-63. 2004
    ....
  35. ncbi Left ventricular assist device implantation after acute anterior wall myocardial infarction and cardiogenic shock: a two-center study
    Nicholas C Dang
    Division of Cardiothoracic Surgery, Department of Surgery, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    J Thorac Cardiovasc Surg 130:693-8. 2005
    ..Confirmation of these findings would require conducting a large, multicenter, randomized clinical trial comparing revascularization versus LVAD support as primary therapy in this setting...
  36. ncbi Long-term mortality and pacing outcomes of patients with permanent pacemaker implantation after cardiac surgery
    Syed S Raza
    Divisions of Cardiology, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA
    Pacing Clin Electrophysiol 34:331-8. 2011
    ..Little is known about the long-term pacing and mortality outcomes and the temporal trends of these patients...
  37. ncbi Acute left atrial thrombus after recombinant factor VIIa administration during left ventricular assist device implantation in a patient with heparin-induced thrombocytopenia
    Ioanna Apostolidou
    Department of Anesthesiology, University of Minneapolis, B515 Mayo, MMC 294, 420 Delaware St, S E, Minneapolis, MN 55455, USA
    Anesth Analg 106:404-8, table of contents. 2008
    ..We believe this is the first documentation of acute left atrial thrombus formation immediately after a single dose of recombinant factor VIIa administration during a left ventricular assist device implantation...
  38. ncbi Interleukin-2 receptor blockade in cardiac transplantation: influence of HLA-DR locus incompatibility on treatment efficacy
    Katherine Lietz
    Transplantation Immunology, Department of Surgery, Columbia-Presbyterian Medical Center, New York, NY 10032, USA
    Transplantation 75:781-7. 2003
    ..CONCLUSIONS: IL-2-receptor blockade is effective for preventing alloreactivity and high-grade rejection in cardiac transplantation; however, its efficacy seemed to be influenced by the degree of donor-recipient, HLA-DR locus mismatching...
  39. ncbi Postcardiac transplant survival in the current era in patients receiving continuous-flow left ventricular assist devices
    Forum Kamdar
    Division of Cardiology, University of Minnesota Medical Center, Minneapolis, MN, USA
    J Thorac Cardiovasc Surg 145:575-81. 2013
    ..However, data on long-term post-transplant survival for these patients are limited. We evaluated the effect of continuous-flow left ventricular assist devices on postcardiac transplant survival in the current era...
  40. ncbi Interactions between the recipient immune system and the left ventricular assist device surface: immunological and clinical implications
    Silviu Itescu
    Department of Surgery, College of Physicians and Surgeons of Columbia University, New York, New York 10032, USA
    Ann Thorac Surg 75:S58-65. 2003
    ....
  41. ncbi Do donor characteristics really matter? Short- and long-term impact of donor characteristics on recipient survival, 1995-1999
    Jonathan M Chen
    Department of Surgery, Division of Cardiothoracic Surgery, New York Presbyterian Hospital, Columbia Presbyterian Campus, New York, New York 10032, USA
    J Heart Lung Transplant 21:608-10. 2002
    ..Few donor characteristics actually impact significantly on recipient outcome, and thus recipient characteristics may figure more prominently than those of the donor toward the risk of death after transplantation...
  42. ncbi Effects of continuous flow left ventricular assist device support on microvascular endothelial function
    Xiaoying Lou
    College of Biological Sciences, University of Minnesota, Minneapolis, MN, USA
    J Cardiovasc Transl Res 5:345-50. 2012
    ....
  43. ncbi Successful treatment of early thrombosis of HeartWare left ventricular assist device with intraventricular thrombolytics
    Abdallah Kamouh
    Division of Cardiovascular Medicine, University of Minnesota Medical Center, Minneapolis, Minnesota 55455, USA
    Ann Thorac Surg 94:281-3. 2012
    ..The patient was discharged with no complications or recurrence of thrombosis and received a successful transplant 1 month later...
  44. ncbi Variation of mortality after coronary artery bypass surgery in relation to hour, day and month of the procedure
    Ann Coumbe
    Division of Cardiology, Veterans Administration Medical Center, One Veterans Drive, Minneapolis, Minnesota 55417, USA
    BMC Cardiovasc Disord 11:63. 2011
    ..Since these challenges are also encountered during coronary artery bypass graft (CABG) surgery that is performed after regular work hours, we assessed whether hour and day of procedure influenced mortality after CABG...
  45. ncbi Mechanical stress: an independent determinant of early bioprosthetic calcification in humans
    Kenneth K Liao
    Division of Cardiothoracic Surgery, University of Minnesota, Minneapolis 55455, USA
    Ann Thorac Surg 86:491-5. 2008
    ..The inflow valve endures a higher closing pressure than the outflow valve; thus, an implanted LVAD offers an ideal human model to study the independent effect of stress on calcification...
  46. ncbi Evaluation of perfusion and viability in hypothermic non-beating isolated porcine hearts using cardiac MRI
    Andrew L Rivard
    Department of Physiology, University of Minnesota, MMC 195, 420 Delaware Street S E, Minneapolis, MN 55455, USA
    Int J Cardiovasc Imaging 22:243-51. 2006
    ..This new application of cardiac MRI in the donor heart is applicable to: (1) assessing marginal hearts, (2) evaluating donor heart preservation techniques, and (3) correlating pre- to post-transplant viability...
  47. ncbi Mechanical circulatory support for bridge to decision: which device and when to decide
    Elizabeth A Ziemba
    Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Card Surg 25:425-33. 2010
    ..This review includes a brief summary of the current assist devices available along with the University of Minnesota's experience with the Levitronix CentriMag system...
  48. ncbi Current state of ventricular assist devices
    Marco Caccamo
    Department of Medicine, Division of Cardiovascular Medicine, University of Minnesota, Minneapolis, MN, USA
    Curr Heart Fail Rep 8:91-8. 2011
    ....
  49. ncbi Immunologic sensitization in recipients of left ventricular assist devices
    Ranjit John
    Department of Surgery Cardiology, Columbia University College of Physicians and Surgeons, New York, NY, USA
    J Thorac Cardiovasc Surg 125:578-91. 2003
    ..We investigated the impact of sensitization on posttransplantation outcomes in 105 consecutive left ventricular assist device recipients...
  50. ncbi A decade experience of cardiac retransplantation in adult recipients
    Veli K Topkara
    Department of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    J Heart Lung Transplant 24:1745-50. 2005
    ..Non-retransplant surgical options should also be considered in these patients. Careful patient selection and risk-assessment is necessary to govern appropriate allocation of limited donor organs...
  51. ncbi B-cell activation and allosensitization after left ventricular assist device implantation is due to T-cell activation and CD40 ligand expression
    Michael Schuster
    College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Hum Immunol 63:211-20. 2002
    ....
  52. ncbi Intravenous pulse administration of cyclophosphamide is an effective and safe treatment for sensitized cardiac allograft recipients
    Silviu Itescu
    College of Physicians and Surgeons of Columbia University, New York, NY 10032, USA
    Circulation 105:1214-9. 2002
    ..We investigated the effect of cyclophosphamide pulse therapy in sensitized cardiac allograft recipients...
  53. ncbi Immunobiologic consequences of assist devices
    Silviu Itescu
    College of Physicians and Surgeons of Columbia University, 622 West 168th Street, New York, NY 10032, USA
    Cardiol Clin 21:119-33, ix-x. 2003
    ....