Mats W Johansson

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. pmc Markers of vascular perturbation correlate with airway structural change in asthma
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, 4285A Medical Sciences Center, 1300 University Avenue, Madison, WI 53706, USA
    Am J Respir Crit Care Med 188:167-78. 2013
  2. pmc α(M)β(2) integrin-mediated adhesion and motility of IL-5-stimulated eosinophils on periostin
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53706, USA
    Am J Respir Cell Mol Biol 48:503-10. 2013
  3. pmc Anti-IL-5 attenuates activation and surface density of β(2) -integrins on circulating eosinophils after segmental antigen challenge
    M W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI, USA
    Clin Exp Allergy 43:292-303. 2013
  4. pmc Platelet activation, P-selectin, and eosinophil β1-integrin activation in asthma
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, 53706, USA
    Am J Respir Crit Care Med 185:498-507. 2012
  5. pmc Activation of beta1 integrins on blood eosinophils by P-selectin
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, 4285A, Medical Sciences Center, 1300 University Avenue, Madison, WI 53706, USA
    Am J Respir Cell Mol Biol 45:889-97. 2011
  6. pmc Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challenge
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI53706, USA
    J Immunol 180:7622-35. 2008
  7. ncbi request reprint Differential engagement of modules 1 and 4 of vascular cell adhesion molecule-1 (CD106) by integrins alpha4beta1 (CD49d/29) and alphaMbeta2 (CD11b/18) of eosinophils
    Steven R Barthel
    Departments of Biomolecular Chemistry and Medicine, University of Wisconsin, 4285A Medical Sciences Center, 1300 University Avenue, Madison, WI 53706 1532, USA
    J Biol Chem 281:32175-87. 2006
  8. pmc Dissection of the hyperadhesive phenotype of airway eosinophils in asthma
    Steven R Barthel
    Department of Biomolecular Chemistry, University of Wisconsin Madison, 4285A Medical Sciences Center, 1300 University Avenue, Madison, Wisconsin 53706 1532, USA
    Am J Respir Cell Mol Biol 35:378-86. 2006
  9. ncbi request reprint Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes
    Mats W Johansson
    Department of Medicine, University of Wisconsin, 4285A, Medical Sciences Center, 1300 University Avenue, Madison, WI 53706 1532, USA
    Am J Respir Cell Mol Biol 31:413-22. 2004
  10. pmc Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma
    Steven R Barthel
    Department of Biomolecular, University of Wisconsin Madison, 4285A Medical Sciences Center, 1300 University Avenue, Madison, WI 53706 1532, USA
    J Leukoc Biol 83:1-12. 2008

Collaborators

Detail Information

Publications13

  1. pmc Markers of vascular perturbation correlate with airway structural change in asthma
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, 4285A Medical Sciences Center, 1300 University Avenue, Madison, WI 53706, USA
    Am J Respir Crit Care Med 188:167-78. 2013
    ..Vascular endothelial cell products have not been explored as a surrogate to mark structural airway changes in asthma...
  2. pmc α(M)β(2) integrin-mediated adhesion and motility of IL-5-stimulated eosinophils on periostin
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53706, USA
    Am J Respir Cell Mol Biol 48:503-10. 2013
    ....
  3. pmc Anti-IL-5 attenuates activation and surface density of β(2) -integrins on circulating eosinophils after segmental antigen challenge
    M W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI, USA
    Clin Exp Allergy 43:292-303. 2013
    ..IL-5 activates α(M) β(2) integrin on blood eosinophils in vitro. Eosinophils in bronchoalveolar lavage (BAL) following segmental antigen challenge have activated β(2) -integrins...
  4. pmc Platelet activation, P-selectin, and eosinophil β1-integrin activation in asthma
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, 53706, USA
    Am J Respir Crit Care Med 185:498-507. 2012
    ..Eosinophil β1-integrin activation correlates inversely with FEV1 and directly with eosinophil-bound P-selectin in subjects with nonsevere allergic asthma...
  5. pmc Activation of beta1 integrins on blood eosinophils by P-selectin
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, 4285A, Medical Sciences Center, 1300 University Avenue, Madison, WI 53706, USA
    Am J Respir Cell Mol Biol 45:889-97. 2011
    ....
  6. pmc Up-regulation and activation of eosinophil integrins in blood and airway after segmental lung antigen challenge
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI53706, USA
    J Immunol 180:7622-35. 2008
    ..Finally, eosinophils present in IL-5-rich airway fluid have a hyperadhesive phenotype associated with increased surface expression of alpha(M)beta(2) and activation of beta(2) integrins...
  7. ncbi request reprint Differential engagement of modules 1 and 4 of vascular cell adhesion molecule-1 (CD106) by integrins alpha4beta1 (CD49d/29) and alphaMbeta2 (CD11b/18) of eosinophils
    Steven R Barthel
    Departments of Biomolecular Chemistry and Medicine, University of Wisconsin, 4285A Medical Sciences Center, 1300 University Avenue, Madison, WI 53706 1532, USA
    J Biol Chem 281:32175-87. 2006
    ..These results demonstrate that alphaMbeta2 modulatesalpha4beta1-mediated eosinophil adhesion to VCAM-1 under both static and flow conditions...
  8. pmc Dissection of the hyperadhesive phenotype of airway eosinophils in asthma
    Steven R Barthel
    Department of Biomolecular Chemistry, University of Wisconsin Madison, 4285A Medical Sciences Center, 1300 University Avenue, Madison, Wisconsin 53706 1532, USA
    Am J Respir Cell Mol Biol 35:378-86. 2006
    ..Thus, the hyperadhesion of airway eosinophils after antigen challenge is mediated by upregulated and activated alphaMbeta2...
  9. ncbi request reprint Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes
    Mats W Johansson
    Department of Medicine, University of Wisconsin, 4285A, Medical Sciences Center, 1300 University Avenue, Madison, WI 53706 1532, USA
    Am J Respir Cell Mol Biol 31:413-22. 2004
    ..Podosome-mediated VCAM-1 clearance may be a mechanism to regulate eosinophil arrest and extravasation in allergic conditions such as asthma...
  10. pmc Roles of integrin activation in eosinophil function and the eosinophilic inflammation of asthma
    Steven R Barthel
    Department of Biomolecular, University of Wisconsin Madison, 4285A Medical Sciences Center, 1300 University Avenue, Madison, WI 53706 1532, USA
    J Leukoc Biol 83:1-12. 2008
    ..Here, we elaborate on how integrins cooperate to mediate eosinophil movement to the asthmatic airway. Antagonists that target integrins represent potentially promising therapies in the treatment of asthma...
  11. ncbi request reprint Cleavage of human 7-domain VCAM-1 (CD106) by thrombin
    Steven R Barthel
    Department of Biomolecular Chemistry, University of Wisconsin Madison, Madison, WI 53706 1532, USA
    Thromb Haemost 95:873-80. 2006
    ..We conclude that cleavage of 7d-VCAM-1 by thrombin is a potential mechanism for differential regulation of VCAM-1 splice forms in white blood cell adhesion and trafficking...
  12. pmc Integrin activation States and eosinophil recruitment in asthma
    Mats W Johansson
    Department of Biomolecular Chemistry, University of Wisconsin Madison, WI, USA
    Front Pharmacol 4:33. 2013
    ....
  13. ncbi request reprint Eosinophil beta 1 integrin activation state correlates with asthma activity in a blind study of inhaled corticosteroid withdrawal
    Mats W Johansson
    J Allergy Clin Immunol 117:1502-4. 2006