Gary L Johanning

Summary

Affiliation: University of Alabama at Birmingham
Country: USA

Publications

  1. ncbi request reprint Effect of high retinoid doses on RAR-beta mRNA expression in female B6D2F1 mice
    G L Johanning
    Department of Nutrition Sciences, The University of Alabama at Birmingham, 35294 3360, USA
    Anticancer Res 21:1691-5. 2001
  2. ncbi request reprint DNA methylation and diet in cancer
    Gary L Johanning
    Department of Nutrition Sciences, The University of Alabama at Birmingham, USA
    J Nutr 132:3814S-3818S. 2002
  3. pmc A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia
    Chandrika J Piyathilake
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Nutrition 27:513-9. 2011
  4. doi request reprint A dietary pattern associated with LINE-1 methylation alters the risk of developing cervical intraepithelial neoplasia
    Chandrika J Piyathilake
    Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Blvd, Webb 326, Birmingham, AL 35294, USA
    Cancer Prev Res (Phila) 5:385-92. 2012
  5. ncbi request reprint Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology
    Cristina Rodriguez-Burford
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Nutr Cancer 43:67-75. 2002
  6. ncbi request reprint Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3
    Olga L Henao
    Department of Epidemiology of the University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Cancer 113:991-7. 2005
  7. pmc Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status
    Chandrika J Piyathilake
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Nutrition 23:229-35. 2007
  8. ncbi request reprint Quantitation of human papillomavirus 16 E6 and E7 DNA and RNA in residual material from ThinPrep Papanicolaou tests using real-time polymerase chain reaction analysis
    Feng Wang-Johanning
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 3300, USA
    Cancer 94:2199-210. 2002
  9. ncbi request reprint Quantitation of HERV-K env gene expression and splicing in human breast cancer
    Feng Wang-Johanning
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 3300, USA
    Oncogene 22:1528-35. 2003
  10. ncbi request reprint Retinoids and epigenetic silencing in cancer
    Gary L Johanning
    Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, AL 35294 3360, USA
    Nutr Rev 61:284-9. 2003

Collaborators

Detail Information

Publications22

  1. ncbi request reprint Effect of high retinoid doses on RAR-beta mRNA expression in female B6D2F1 mice
    G L Johanning
    Department of Nutrition Sciences, The University of Alabama at Birmingham, 35294 3360, USA
    Anticancer Res 21:1691-5. 2001
    ..Bladder RAR-beta mRNA levels, however, were significantly decreased in mice fed 13-cis RA or 4-HPR. These results suggest that feeding high levels of retinoids to mice results in tissue-specific elfects on expression of RAR-beta mRNA...
  2. ncbi request reprint DNA methylation and diet in cancer
    Gary L Johanning
    Department of Nutrition Sciences, The University of Alabama at Birmingham, USA
    J Nutr 132:3814S-3818S. 2002
    ....
  3. pmc A higher degree of LINE-1 methylation in peripheral blood mononuclear cells, a one-carbon nutrient related epigenetic alteration, is associated with a lower risk of developing cervical intraepithelial neoplasia
    Chandrika J Piyathilake
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Nutrition 27:513-9. 2011
    ..The objective of the study was to evaluate LINE-1 methylation as an intermediate biomarker for the effect of folate and vitamin B12 on the occurrence of higher grades of cervical intraepithelial neoplasia (CIN ≥ 2)...
  4. doi request reprint A dietary pattern associated with LINE-1 methylation alters the risk of developing cervical intraepithelial neoplasia
    Chandrika J Piyathilake
    Department of Nutrition Sciences, University of Alabama at Birmingham, 1675 University Blvd, Webb 326, Birmingham, AL 35294, USA
    Cancer Prev Res (Phila) 5:385-92. 2012
    ..The degree of PBMC L1 methylation may serve as a biomarker for monitoring the effectiveness of dietary modifications needed for reducing the risk of CIN 2+...
  5. ncbi request reprint Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology
    Cristina Rodriguez-Burford
    Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Nutr Cancer 43:67-75. 2002
    ..It would appear that the observed decrease in mammary cancers observed with moderate reductions in body weight gain might be due to multiple related factors different from those related to 4-HPR treatment...
  6. ncbi request reprint Women with polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and methionine synthase (MS) are less likely to have cervical intraepithelial neoplasia (CIN) 2 or 3
    Olga L Henao
    Department of Epidemiology of the University of Alabama at Birmingham, Birmingham, AL, USA
    Int J Cancer 113:991-7. 2005
    ..62). We conclude that these polymorphisms in the folate metabolic pathway were associated with a lower likelihood of CIN 2 or 3 in a population exposed to adequate amounts of folate from exposure to food fortification with folic acid...
  7. pmc Protective association of MTHFR polymorphism on cervical intraepithelial neoplasia is modified by riboflavin status
    Chandrika J Piyathilake
    University of Alabama at Birmingham, Birmingham, Alabama, USA
    Nutrition 23:229-35. 2007
    ..40, 95% confidence interval [CI] 0.21-0.78, P = 0.007). In the present study, we tested whether this protective association is modified by circulating riboflavin status in the same study population...
  8. ncbi request reprint Quantitation of human papillomavirus 16 E6 and E7 DNA and RNA in residual material from ThinPrep Papanicolaou tests using real-time polymerase chain reaction analysis
    Feng Wang-Johanning
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294 3300, USA
    Cancer 94:2199-210. 2002
    ..The goal of this study was to determine the potential clinical uses of real-time polymerase chain reaction (PCR) and reverse transcription-PCR (RT-PCR) methods for evaluating HPV-16 E6 and E7 oncogene expression...
  9. ncbi request reprint Quantitation of HERV-K env gene expression and splicing in human breast cancer
    Feng Wang-Johanning
    Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294 3300, USA
    Oncogene 22:1528-35. 2003
    ..The selective expression and distribution of multiple HERV-K endogenous retroviral element splice variants in breast cancer, but not in normal controls, suggests that they are novel breast tumor markers...
  10. ncbi request reprint Retinoids and epigenetic silencing in cancer
    Gary L Johanning
    Department of Nutrition Sciences, The University of Alabama at Birmingham, Birmingham, AL 35294 3360, USA
    Nutr Rev 61:284-9. 2003
    ..Two recent studies have established a mechanistic link between a vitamin A metabolite and epigenetic alterations of its target promoter that could provide insights about the role of vitamin A in cancer prevention...
  11. ncbi request reprint Cellular vitamins, DNA methylation and cancer risk
    Chandrika J Piyathilake
    Department of Nutrition Sciences, The University of Alabama at Birmingham, 35294, USA
    J Nutr 132:2340S-2344S. 2002
    ....
  12. pmc A higher degree of methylation of the HPV 16 E6 gene is associated with a lower likelihood of being diagnosed with cervical intraepithelial neoplasia
    Chandrika J Piyathilake
    Department of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Cancer 117:957-63. 2011
    ....
  13. ncbi request reprint Effects of energy expenditure and Ucp1 on photoperiod-induced weight gain in collard lemmings
    Charles Stephenson Powell
    Department of Nutrition Sciences, The University of Alabama at Birmingham, 35294 3360, USA
    Obes Res 10:541-50. 2002
    ..To determine the role of total energy expenditure (TEE) and its components in the ability of collared lemmings to increase weight in response to a decrease in photoperiod...
  14. doi request reprint Human endogenous retrovirus K triggers an antigen-specific immune response in breast cancer patients
    Feng Wang-Johanning
    Department of Veterinary Sciences and Michale E Keeling Center for Comparative Medicine and Research, The University of Texas M D Anderson Cancer Center, Houston, TX 78602 6621, USA
    Cancer Res 68:5869-77. 2008
    ..These findings suggest that retroviral gene products are capable of acting as tumor-associated antigens activating both T-cell and B-cell responses in BC patients...
  15. ncbi request reprint Expression of multiple human endogenous retrovirus surface envelope proteins in ovarian cancer
    Feng Wang-Johanning
    Department of Veterinary Sciences and Michale E Keeling Center for Comparative Medicine and Research, University of Texas MD Anderson Cancer Center, Houston, TX 78602, USA
    Int J Cancer 120:81-90. 2007
    ..HERV env proteins, and especially those expressed on the cell surface, may serve as novel tumor targets for detection, diagnosis and immunotherapy of ovarian cancer...
  16. ncbi request reprint Viral detection
    Feng Wang-Johanning
    Department of Veterinary Sciences, University of Texas M D Anderson Cancer Center, Houston, TX, USA
    Methods Mol Biol 292:3-14. 2005
    ..Other methods for viral nucleic acid detection, including nested PCR amplification, ligase chain reaction, and enzyme-linked immunosorbent assay (ELISA), are also briefly discussed...
  17. ncbi request reprint Detecting the expression of human endogenous retrovirus E envelope transcripts in human prostate adenocarcinoma
    Feng Wang-Johanning
    Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Cancer 98:187-97. 2003
    ..The authors report that, in the current study, transcripts encoding the envelope region of an HERV family, HERV-E, were expressed in human prostate carcinoma...
  18. ncbi request reprint Efficacy of a medical nutriment in the treatment of cancer
    Gary L Johanning
    Michale E Keeling Center for Comparative Medicine and Research, University of Texas M D Anderson Cancer Center, Bastrop, TX, USA
    Altern Ther Health Med 13:56-63; quiz 64-5. 2007
  19. ncbi request reprint Sheep stromal-epithelial cell interactions and ovarian tumor progression
    Feng Wang-Johanning
    Department of Veterinary Sciences, Michale E Keeling Center for Comparative Medicine and Research, The University of Texas M D Anderson Cancer Center, Bastrop, TX, USA
    Int J Cancer 121:2346-54. 2007
    ..Our data provide compelling support for the importance of stromal-epithelial cell interactions during tumor progression, and show for the first time that immortalized and transformed OSCs promote growth of ovarian epithelial tumors...
  20. ncbi request reprint Micronutrients and cancer therapy
    Martin A Whiteside
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892, USA
    Nutr Rev 62:142-7. 2004
    ..To date, few well-controlled clinical trials have been conducted to evaluate the efficacy of micronutrients in promoting the sensitivity of tumors to chemotherapeutic agents...
  21. ncbi request reprint A novel time-course cDNA microarray analysis method identifies genes associated with the development of cisplatin resistance
    Martin A Whiteside
    Cancer Prevention Fellowship Program, Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    Oncogene 23:744-52. 2004
    ..This small time-ordered series identified novel genes associated with cisplatin resistance. This kind of analysis should be viewed as a first step towards building gene-regulatory networks...
  22. ncbi request reprint Intrinsic cisplatin resistance in lung and ovarian cancer cells propagating in medium acutely depleted of folate
    Martin A Whiteside
    National Cancer Institute, Division of Cancer Prevention, Bethesda, MD 20892, USA
    Nutr Cancer 54:274-84. 2006
    ..If these results are confirmed by in vivo human studies, it would suggest that the folate status of the recipient of cisplatin might have an impact on response to that chemotherapeutic agent...