Glen C Jickling

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Genome response to tissue plasminogen activator in experimental ischemic stroke
    Glen C Jickling
    Department of Neurology and M, I, N, d, Institute, University of California at Davis, Sacramento, California 95817, USA
    BMC Genomics 11:254. 2010
  2. pmc Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct location
    Glen C Jickling
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Stroke 43:2036-41. 2012
  3. pmc Ischemic transient neurological events identified by immune response to cerebral ischemia
    Glen C Jickling
    University of California at Davis, MIND Institute, 2805 50th Street, Sacramento, CA 95817, USA
    Stroke 43:1006-12. 2012
  4. pmc Signatures of cardioembolic and large-vessel ischemic stroke
    Glen C Jickling
    Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Ann Neurol 68:681-92. 2010
  5. pmc Profiles of lacunar and nonlacunar stroke
    Glen C Jickling
    Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Ann Neurol 70:477-85. 2011
  6. pmc Blood biomarkers of ischemic stroke
    Glen C Jickling
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Neurotherapeutics 8:349-60. 2011
  7. pmc Effects of gender on gene expression in the blood of ischemic stroke patients
    Yingfang Tian
    Department of Neurology, The MIND Institute, University of California at Davis, Sacramento, CA, USA
    J Cereb Blood Flow Metab 32:780-91. 2012
  8. doi request reprint GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study
    Yingfang Tian
    University of California at Davis, M I N D, Institute and Department of Neurology, USA
    Brain Res 1381:228-36. 2011
  9. pmc Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study
    Yingfang Tian
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
    BMC Med Genomics 5:49. 2012
  10. pmc Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controls
    Yingfang Tian
    Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, California 95817, USA
    Gend Med 9:68-75.e3. 2012

Detail Information

Publications18

  1. pmc Genome response to tissue plasminogen activator in experimental ischemic stroke
    Glen C Jickling
    Department of Neurology and M, I, N, d, Institute, University of California at Davis, Sacramento, California 95817, USA
    BMC Genomics 11:254. 2010
    ..To further delineate tPA functions in the blood, we examined the gene expression profiles induced by tPA in a rat model of ischemic stroke...
  2. pmc Prediction of cardioembolic, arterial, and lacunar causes of cryptogenic stroke by gene expression and infarct location
    Glen C Jickling
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Stroke 43:2036-41. 2012
    ..We demonstrate how gene expression profiles in blood can be used in conjunction with a measure of infarct location on neuroimaging to predict a probable cause in cryptogenic stroke...
  3. pmc Ischemic transient neurological events identified by immune response to cerebral ischemia
    Glen C Jickling
    University of California at Davis, MIND Institute, 2805 50th Street, Sacramento, CA 95817, USA
    Stroke 43:1006-12. 2012
    ..Ischemia of cerebral tissue elicits an immune response in stroke and transient ischemic attack (TIA). This response, as detected by RNA expressed in immune cells, could potentially distinguish ischemic from nonischemic TNE...
  4. pmc Signatures of cardioembolic and large-vessel ischemic stroke
    Glen C Jickling
    Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Ann Neurol 68:681-92. 2010
    ..We sought to determine whether gene expression signatures in blood can distinguish between cardioembolic and large-vessel causes of stroke, and whether these profiles can predict stroke etiology in the cryptogenic group...
  5. pmc Profiles of lacunar and nonlacunar stroke
    Glen C Jickling
    Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Ann Neurol 70:477-85. 2011
    ..We sought to distinguish lacunar from nonlacunar causes of SDIs using a gene expression profile...
  6. pmc Blood biomarkers of ischemic stroke
    Glen C Jickling
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Neurotherapeutics 8:349-60. 2011
    ..With further well designed study and careful validation, the development of blood biomarkers to improve the care of patients with ischemic stroke may be achieved...
  7. pmc Effects of gender on gene expression in the blood of ischemic stroke patients
    Yingfang Tian
    Department of Neurology, The MIND Institute, University of California at Davis, Sacramento, CA, USA
    J Cereb Blood Flow Metab 32:780-91. 2012
    ..Gender affects gene expression in the blood of IS patients, which likely implies gender differences in immune, inflammatory, and cell death responses to stroke...
  8. doi request reprint GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot study
    Yingfang Tian
    University of California at Davis, M I N D, Institute and Department of Neurology, USA
    Brain Res 1381:228-36. 2011
    ..This pilot study suggests that at least some of these GABA- and ACh-related genes observed in blood that correlate with tics or are alternatively spliced are involved in the pathophysiology of TS and tics...
  9. pmc Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot study
    Yingfang Tian
    MIND Institute and Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
    BMC Med Genomics 5:49. 2012
    ..This study determined if gene expression in blood correlated significantly with IA and/or HI rating scale scores in participants with TS...
  10. pmc Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controls
    Yingfang Tian
    Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, California 95817, USA
    Gend Med 9:68-75.e3. 2012
    ....
  11. doi request reprint Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: a pilot study
    Michelle L Apperson
    Department of Neurology and the M I N D Institute, University of California at Davis, Sacramento, CA 95817, USA
    J Neuroimmunol 257:90-6. 2013
    ..Different risk alleles appear to be associated with different patterns of gene expression that may reflect differences in pathophysiology of these two MS subtypes. These preliminary data will need to be confirmed in future studies...
  12. pmc RNA expression profiles from blood for the diagnosis of stroke and its causes
    Frank R Sharp
    Department of Neurology, University of California at Davis, Sacramento, CA, USA
    J Child Neurol 26:1131-6. 2011
    ..These profiles will be useful for predicting the causes of cryptogenic stroke. The results in adults suggest that similar diagnostic tools could be developed for children...
  13. pmc Molecular markers and mechanisms of stroke: RNA studies of blood in animals and humans
    Frank R Sharp
    Department of Neurology, MIND Institute, University of California at Davis, Sacramento, California 95817, USA
    J Cereb Blood Flow Metab 31:1513-31. 2011
    ..New techniques to measure all coding and noncoding RNAs along with alternatively spliced transcripts will markedly advance molecular studies of human stroke...
  14. doi request reprint Differences in exon expression and alternatively spliced genes in blood of multiple sclerosis compared to healthy control subjects
    Yingfang Tian
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, United States
    J Neuroimmunol 230:124-9. 2011
    ..However, given that multiple comparisons were performed on a very small sample, these preliminary findings require confirmation using a much larger independent cohort...
  15. doi request reprint Hemorrhagic transformation after ischemic stroke in animals and humans
    Glen C Jickling
    Department of Neurology, MIND Institute, University of California at Davis, Sacramento, California, USA
    J Cereb Blood Flow Metab 34:185-99. 2014
    ..Though remarkable advances in our understanding of HT have been made, additional efforts are needed to translate these discoveries to the clinic and reduce the impact of HT on patients with ischemic stroke. ..
  16. doi request reprint Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cells
    Da Zhi Liu
    Department of Neurology and the M I N D Institute, University of California at Davis, Sacramento, CA 95817, USA
    Gene 495:120-7. 2012
    ..g., miR-370, miR-9, miR-672) in NBCs are associated with cancer pathways. These results provide a library of negative mRNAmiRNA networks that are likely involved in the cellular processes of differentiation and division...
  17. pmc Exon expression and alternatively spliced genes in Tourette Syndrome
    Yingfang Tian
    M I N D Institute, Department of Neurology, University of California at Davis, Sacramento, 95817, USA
    Am J Med Genet B Neuropsychiatr Genet 156:72-8. 2011
    ..However, the findings are tempered by the small sample size and multiple comparisons and require confirmation using PCR or deep RNA sequencing and a much larger patient population...
  18. doi request reprint Ischemic stroke biomarkers in blood
    Lena Rothstein
    Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
    Biomark Med 7:37-47. 2013
    ..In this review, the authors provide a summary of biomarkers that have been divided by their potential clinical application...