Xiangning Jiang

Summary

Affiliation: University of California
Country: USA

Publications

  1. doi request reprint Activated Src kinases interact with the N-methyl-D-aspartate receptor after neonatal brain ischemia
    Xiangning Jiang
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0663, USA
    Ann Neurol 63:632-41. 2008
  2. pmc Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain
    Xiangning Jiang
    Department of Neurology, University of California, San Francisco, CA 94143, United States
    Neurosci Lett 503:215-9. 2011
  3. pmc HIF-1 alpha-deficient mice have increased brain injury after neonatal hypoxia-ischemia
    R Ann Sheldon
    Department of Neurology, University of California, San Francisco, CA 94143 0663, USA
    Dev Neurosci 31:452-8. 2009
  4. ncbi request reprint Differential vulnerability of immature murine neurons to oxygen-glucose deprivation
    Xiangning Jiang
    Department of Neurology, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0663, USA
    Exp Neurol 190:224-32. 2004
  5. ncbi request reprint A role for hypoxia-inducible factor-1alpha in desferoxamine neuroprotection
    Shannon Elise Goldsmith Hamrick
    Department of Pediatrics, University of California San Francisco, 521 Parnassus Avenue, C 215, San Francisco, CA 94143 0663, USA
    Neurosci Lett 379:96-100. 2005
  6. pmc Exogenous low dose hydrogen peroxide increases hypoxia-inducible factor-1alpha protein expression and induces preconditioning protection against ischemia in primary cortical neurons
    Shengjun Chang
    Department of Neurology, University of California, San Francisco, CA 94143 0663, USA
    Neurosci Lett 441:134-8. 2008
  7. ncbi request reprint Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model
    Dezhi Mu
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143, USA
    Neurobiol Dis 14:524-34. 2003
  8. pmc Role of vasodilator stimulated phosphoprotein in VEGF induced blood-brain barrier permeability in endothelial cell monolayers
    Brandon Davis
    Department of Neurology, University of California, San Francisco, CA 94143, USA
    Int J Dev Neurosci 28:423-8. 2010
  9. pmc Enhanced NMDA receptor tyrosine phosphorylation and increased brain injury following neonatal hypoxia-ischemia in mice with neuronal Fyn overexpression
    Renatta Knox
    Department of Neurology, University of California, San Francisco, CA 94158, USA
    Neurobiol Dis 51:113-9. 2013
  10. ncbi request reprint Manipulation of antioxidant pathways in neonatal murine brain
    R Ann Sheldon
    Department of Neurology, University of California San Francisco, San Francisco, California 94143
    Pediatr Res 56:656-62. 2004

Collaborators

Detail Information

Publications14

  1. doi request reprint Activated Src kinases interact with the N-methyl-D-aspartate receptor after neonatal brain ischemia
    Xiangning Jiang
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143 0663, USA
    Ann Neurol 63:632-41. 2008
    ....
  2. pmc Developmental localization of NMDA receptors, Src and MAP kinases in mouse brain
    Xiangning Jiang
    Department of Neurology, University of California, San Francisco, CA 94143, United States
    Neurosci Lett 503:215-9. 2011
    ....
  3. pmc HIF-1 alpha-deficient mice have increased brain injury after neonatal hypoxia-ischemia
    R Ann Sheldon
    Department of Neurology, University of California, San Francisco, CA 94143 0663, USA
    Dev Neurosci 31:452-8. 2009
    ..05) and was more severe in the cortex. Genetic reduction of neuronal HIF-1 alpha results in a worsening of injury after neonatal HI, with a region-specific role for HIF-1 alpha in the setting of neonatal brain injury...
  4. ncbi request reprint Differential vulnerability of immature murine neurons to oxygen-glucose deprivation
    Xiangning Jiang
    Department of Neurology, University of California San Francisco, 521 Parnassus Avenue, San Francisco, CA 94143 0663, USA
    Exp Neurol 190:224-32. 2004
    ....
  5. ncbi request reprint A role for hypoxia-inducible factor-1alpha in desferoxamine neuroprotection
    Shannon Elise Goldsmith Hamrick
    Department of Pediatrics, University of California San Francisco, 521 Parnassus Avenue, C 215, San Francisco, CA 94143 0663, USA
    Neurosci Lett 379:96-100. 2005
    ..006). This protection was diminished with transfection of antiHIF-1alpha (p = 0.049). Blocking HIF-1alpha reduces DFO protection suggesting that DFO protects through iron chelation and HIF-1alpha induction...
  6. pmc Exogenous low dose hydrogen peroxide increases hypoxia-inducible factor-1alpha protein expression and induces preconditioning protection against ischemia in primary cortical neurons
    Shengjun Chang
    Department of Neurology, University of California, San Francisco, CA 94143 0663, USA
    Neurosci Lett 441:134-8. 2008
    ..For both preconditioning paradigms, HIF-1alpha expression level declined to baseline at 72 h. Our results suggest that low levels of H(2)O(2) may up-regulate HIF-1alpha protein and thereby mediate H/I preconditioning protection...
  7. ncbi request reprint Regulation of hypoxia-inducible factor 1alpha and induction of vascular endothelial growth factor in a rat neonatal stroke model
    Dezhi Mu
    Department of Neurology, University of California San Francisco, San Francisco, CA 94143, USA
    Neurobiol Dis 14:524-34. 2003
    ..The presence of HIF-1alpha and VEGF after moderate ischemia-reperfusion injury suggests potential avenues to exploit for neuroprotection...
  8. pmc Role of vasodilator stimulated phosphoprotein in VEGF induced blood-brain barrier permeability in endothelial cell monolayers
    Brandon Davis
    Department of Neurology, University of California, San Francisco, CA 94143, USA
    Int J Dev Neurosci 28:423-8. 2010
    ..We also found that VASP at tight junctions was co-localized with ZO-1 in cell-cell contacts. Our findings show that VASP phosphorylation is affected by hypoxia and VEGFR2 inhibition suggesting a role for VASP in BBB permeability...
  9. pmc Enhanced NMDA receptor tyrosine phosphorylation and increased brain injury following neonatal hypoxia-ischemia in mice with neuronal Fyn overexpression
    Renatta Knox
    Department of Neurology, University of California, San Francisco, CA 94158, USA
    Neurobiol Dis 51:113-9. 2013
    ..Our findings suggest a role for Fyn kinase in neuronal death after neonatal HI, possibly via up-regulation of NMDA receptor tyrosine phosphorylation...
  10. ncbi request reprint Manipulation of antioxidant pathways in neonatal murine brain
    R Ann Sheldon
    Department of Neurology, University of California San Francisco, San Francisco, California 94143
    Pediatr Res 56:656-62. 2004
    ..008). These findings support the hypothesis that the immature brain has limited GPX activity and is more susceptible to oxidative damage and may explain the paradoxical effect seen in ischemic neonatal brain when SOD1 is overexpressed...
  11. ncbi request reprint Neonatal hypoxia-ischemia differentially upregulates MAGUKs and associated proteins in PSD-93-deficient mouse brain
    Xiangning Jiang
    Department of Neurology, University of California, San Francisco 94143 0663, USA
    Stroke 34:2958-63. 2003
    ..We investigated whether deletion of PSD-93 would dissociate the NMDAR from nNOS and be neuroprotective...
  12. doi request reprint Phenotype and secretory responses to oxidative stress in microglia
    Praneeti Pathipati
    Department of Neurology, University of California San Francisco, San Francisco, CA 94158, USA
    Dev Neurosci 35:241-54. 2013
    ..Together, these specific effects can be used to clarify the microglial cell responses following injury in the immature brain. ..
  13. ncbi request reprint Expression of Nogo-A and NgR in the developing rat brain after hypoxia-ischemia
    Hua Wang
    Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China
    Brain Res 1114:212-20. 2006
    ..Our findings of upregulation of neurite growth inhibitor Nogo-A and its receptor NgR in ischemic cortex suggest that Nogo-A and NgR may participate in the pathology seen after HI in neonatal rats...
  14. ncbi request reprint Expression of tumor necrosis factor alpha and neuronal apoptosis in the developing rat brain after neonatal stroke
    Meng Mao
    Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, China
    Neurosci Lett 403:227-32. 2006
    ..Our findings suggest that TNFalpha expression increases after neonatal stroke and is associated with neuronal apoptosis after transient focal cerebral ischemia...