Wangcun Jia

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Photocoagulation of dermal blood vessels with multiple laser pulses in an in vivo microvascular model
    Wangcun Jia
    Beckman Laser Institute and Medical Clinic, Department of Surgery, University of California, Irvine, California 92617 3010, USA
    Lasers Surg Med 44:144-51. 2012
  2. ncbi request reprint Heat-transfer dynamics during cryogen spray cooling of substrate at different initial temperatures
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, CA 92612 1475, USA
    Phys Med Biol 49:5295-308. 2004
  3. ncbi request reprint Improvement of port wine stain laser therapy by skin preheating prior to cryogen spray cooling: a numerical simulation
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, 92612, USA 92612, USA
    Lasers Surg Med 38:155-62. 2006
  4. pmc Long-term blood vessel removal with combined laser and topical rapamycin antiangiogenic therapy: implications for effective port wine stain treatment
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, California 92617 3010, USA
    Lasers Surg Med 42:105-12. 2010
  5. ncbi request reprint Treatment of cutaneous vascular lesions using multiple-intermittent cryogen spurts and two-wavelength laser pulses: numerical and animal studies
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, California 92612 1475, USA
    Lasers Surg Med 39:494-503. 2007
  6. ncbi request reprint Dynamic skin cooling with an environmentally compatible alternative cryogen during laser surgery
    Wangcun Jia
    Beckman Laser Institute, University of California Irvine, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Lasers Surg Med 39:776-81. 2007
  7. doi request reprint Topical rapamycin suppresses the angiogenesis pathways induced by pulsed dye laser: molecular mechanisms of inhibition of regeneration and revascularization of photocoagulated cutaneous blood vessels
    Wenbin Tan
    Department of Surgery, Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, California 92617, USA
    Lasers Surg Med 44:796-804. 2012
  8. ncbi request reprint Thermal responses of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses
    Rong Zhang
    Beckman Laser Institute, University of California, Irvine, 92612, USA
    Lasers Surg Med 38:137-41. 2006
  9. pmc High-resolution imaging of microvasculature in human skin in-vivo with optical coherence tomography
    Gangjun Liu
    Beckman Laser Institute, University of California, Irvine, Irvine, California 92612, USA
    Opt Express 20:7694-705. 2012
  10. ncbi request reprint Extent of lateral epidermal protection afforded by a cryogen spray against laser irradiation
    Walfre Franco
    Department of Mechanical Engineering, University of California, Riverside, California 92521, USA
    Lasers Surg Med 39:414-21. 2007

Collaborators

Detail Information

Publications16

  1. pmc Photocoagulation of dermal blood vessels with multiple laser pulses in an in vivo microvascular model
    Wangcun Jia
    Beckman Laser Institute and Medical Clinic, Department of Surgery, University of California, Irvine, California 92617 3010, USA
    Lasers Surg Med 44:144-51. 2012
    ..To improve PWS therapeutic efficacy, we evaluated the performance of an approach based on multiple laser pulses (MLP) to enhance blood vessel photocoagulation...
  2. ncbi request reprint Heat-transfer dynamics during cryogen spray cooling of substrate at different initial temperatures
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, CA 92612 1475, USA
    Phys Med Biol 49:5295-308. 2004
    ..It is concluded that heat transfer between the cryogen spray and skin phantom remains in the nucleate boiling region even if T0 is 80 degrees C...
  3. ncbi request reprint Improvement of port wine stain laser therapy by skin preheating prior to cryogen spray cooling: a numerical simulation
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, 92612, USA 92612, USA
    Lasers Surg Med 38:155-62. 2006
    ....
  4. pmc Long-term blood vessel removal with combined laser and topical rapamycin antiangiogenic therapy: implications for effective port wine stain treatment
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, California 92617 3010, USA
    Lasers Surg Med 42:105-12. 2010
    ..Our objectives were to (1) investigate whether topical RPM can inhibit reperfusion of photocoagulated blood vessels in an animal model and (2) determine the effective RPM concentration required to achieve this objective...
  5. ncbi request reprint Treatment of cutaneous vascular lesions using multiple-intermittent cryogen spurts and two-wavelength laser pulses: numerical and animal studies
    Wangcun Jia
    Beckman Laser Institute, University of California, Irvine, California 92612 1475, USA
    Lasers Surg Med 39:494-503. 2007
    ..In this study, the feasibility of applying multiple cryogen spurts intermittently with multiple two-wavelength laser pulses (MCS-MTWLP) was studied using numerical and animal models...
  6. ncbi request reprint Dynamic skin cooling with an environmentally compatible alternative cryogen during laser surgery
    Wangcun Jia
    Beckman Laser Institute, University of California Irvine, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Lasers Surg Med 39:776-81. 2007
    ..However, R134a has a very high global warming potential (GWP = 1300). Our objective was to evaluate the cooling effectiveness of an alternative cryogen with a much lower GWP, namely liquid carbon dioxide (CO(2), GWP = 1)...
  7. doi request reprint Topical rapamycin suppresses the angiogenesis pathways induced by pulsed dye laser: molecular mechanisms of inhibition of regeneration and revascularization of photocoagulated cutaneous blood vessels
    Wenbin Tan
    Department of Surgery, Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, California 92617, USA
    Lasers Surg Med 44:796-804. 2012
    ..Herein, we attempt to further elucidate the molecular pathophysiology on the inhibition of the regeneration and revascularization of photocoagulated blood vessels by topical RPM in an animal model...
  8. ncbi request reprint Thermal responses of ex vivo human skin during multiple cryogen spurts and 1,450 nm laser pulses
    Rong Zhang
    Beckman Laser Institute, University of California, Irvine, 92612, USA
    Lasers Surg Med 38:137-41. 2006
    ..The objective of this study is to measure temperature variations at the epidermal-dermal junction in ex vivo human skin during three clinically relevant multiple cryogen spurt-laser pulse sequences (MCS-LPS)...
  9. pmc High-resolution imaging of microvasculature in human skin in-vivo with optical coherence tomography
    Gangjun Liu
    Beckman Laser Institute, University of California, Irvine, Irvine, California 92612, USA
    Opt Express 20:7694-705. 2012
    ..2 mm in human skin. These results collectively demonstrated the potential of the method to monitor the microvasculature during disease progression and in response to therapeutic intervention...
  10. ncbi request reprint Extent of lateral epidermal protection afforded by a cryogen spray against laser irradiation
    Walfre Franco
    Department of Mechanical Engineering, University of California, Riverside, California 92521, USA
    Lasers Surg Med 39:414-21. 2007
    ..The objective of the present study is to investigate the extent of lateral epidermal protection afforded by a cryogen spray during laser irradiation...
  11. ncbi request reprint Infrared measurement of human skin temperature to predict the individual maximum safe radiant exposure (IMSRE)
    Wim Verkruysse
    Beckman Laser Institute and Medical Clinic, University of California Irvine, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Lasers Surg Med 39:757-66. 2007
    ..An objective and quantitative method to assess the individual maximum safe radiant exposure (IMSRE) would help clinicians optimize LHR while at the same time providing the safest possible laser therapy...
  12. pmc Fluid and thermal dynamics of cryogen sprays impinging on a human tissue phantom
    Walfre Franco
    Beckman Laser Institute, University of California, Irvine, CA 92612, USA
    J Biomech Eng 130:051005. 2008
    ..Temperatures in human tissue during CSC for the spray system and parameters used herein are estimated to be approximately -19 degrees C at the stratum corneum surface and >0 degrees C across the epidermis...
  13. pmc Wide-field functional imaging of blood flow and hemoglobin oxygen saturation in the rodent dorsal window chamber
    Austin J Moy
    Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Microvasc Res 82:199-209. 2011
    ..Compared with intravital microscopy, wide-field functional imaging requires simple instrumentation, is inexpensive, and can give detailed metabolic information over a wide field of view...
  14. pmc Intensity-based modified Doppler variance algorithm: application to phase instable and phase stable optical coherence tomography systems
    Gangjun Liu
    Beckman Laser Institute, University of California, Irvine, Irvine, California 92612, USA
    Opt Express 19:11429-40. 2011
    ..In-vivo imaging of the human choroidal blood vessel network is demonstrated with the proposed method under the phase stable situation. Depth-resolved fine choroidal blood vessel networks are shown...
  15. pmc The importance of long-term monitoring to evaluate the microvascular response to light-based therapies
    Bernard Choi
    J Invest Dermatol 128:485-8. 2008
  16. pmc Can the wound healing response of human skin be modulated after laser treatment and the effects of exposure extended? Implications on the combined use of the pulsed dye laser and a topical angiogenesis inhibitor for treatment of port wine stain birthmarks
    Thuy L Phung
    Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Lasers Surg Med 40:1-5. 2008