Dan Jia

Summary

Affiliation: University of Arkansas for Medical Sciences
Country: USA

Publications

  1. pmc Repression of multiple myeloma growth and preservation of bone with combined radiotherapy and anti-angiogenic agent
    Dan Jia
    Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR72205, USA
    Radiat Res 173:809-17. 2010
  2. ncbi Pregnancy-associated plasma protein-A proteolytic activity in rat vertebral cell cultures: stimulation by dexamethasone--a potential mechanism for glucocorticoid regulation of osteoprogenitor proliferation and differentiation
    Dan Jia
    Dental Research Institute, Faculty of Dentistry, University of Toronto, Ontario, Canada
    J Cell Physiol 204:848-58. 2005
  3. pmc Rapid loss of bone mass and strength in mice after abdominal irradiation
    Dan Jia
    Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Radiat Res 176:624-35. 2011
  4. ncbi The skeletal effects of glucocorticoid excess override those of orchidectomy in mice
    Robert S Weinstein
    Center for Osteoporosis and Metabolic Bone Diseases, Department of Internal Medicine, Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205 7199, USA
    Endocrinology 145:1980-7. 2004
  5. ncbi Expression of insulin-like growth factor system constituents in differentiating rat osteoblastic cell populations
    Dan Jia
    Faculty of Dentistry, University of Toronto, Toronto, Ont, Canada M5G 1G6
    Growth Horm IGF Res 12:399-410. 2002
  6. ncbi Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength
    CHARLES A O'BRIEN
    Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases, Department of Internal Medicine, Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, Little Rock 72205 7199, USA
    Endocrinology 145:1835-41. 2004
  7. pmc Prevention and mitigation of acute death of mice after abdominal irradiation by the antioxidant N-acetyl-cysteine (NAC)
    Dan Jia
    Department of Radiation Oncology, University of Arkansas for Medical Sciences College of Medicine, Little Rock, Arkansas 72205, USA
    Radiat Res 173:579-89. 2010

Detail Information

Publications7

  1. pmc Repression of multiple myeloma growth and preservation of bone with combined radiotherapy and anti-angiogenic agent
    Dan Jia
    Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, AR72205, USA
    Radiat Res 173:809-17. 2010
    ..These results suggest that radiotherapy, when primed by anti-angiogenic agents, may be a potent therapy for focal multiple myeloma...
  2. ncbi Pregnancy-associated plasma protein-A proteolytic activity in rat vertebral cell cultures: stimulation by dexamethasone--a potential mechanism for glucocorticoid regulation of osteoprogenitor proliferation and differentiation
    Dan Jia
    Dental Research Institute, Faculty of Dentistry, University of Toronto, Ontario, Canada
    J Cell Physiol 204:848-58. 2005
    ..Our findings underscore a novel mechanism whereby GCs increase IGF responses in rat bone cells via PAPP-A-induced IGFBP-4 proteolysis...
  3. pmc Rapid loss of bone mass and strength in mice after abdominal irradiation
    Dan Jia
    Department of Radiation Oncology, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA
    Radiat Res 176:624-35. 2011
    ..These effects are bone type- and region-specific but are independent of radiation fractionation. The radiation-induced abscopal damage to the skeleton is manifested by the deterioration of biomechanical properties of the affected bone...
  4. ncbi The skeletal effects of glucocorticoid excess override those of orchidectomy in mice
    Robert S Weinstein
    Center for Osteoporosis and Metabolic Bone Diseases, Department of Internal Medicine, Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205 7199, USA
    Endocrinology 145:1980-7. 2004
    ..These data demonstrate that hypogonadism does not occur in or contribute to glucocorticoid-induced osteoporosis and that the adverse skeletal effects of glucocorticoid excess override those of orchidectomy...
  5. ncbi Expression of insulin-like growth factor system constituents in differentiating rat osteoblastic cell populations
    Dan Jia
    Faculty of Dentistry, University of Toronto, Toronto, Ont, Canada M5G 1G6
    Growth Horm IGF Res 12:399-410. 2002
    ..Some of these changes are dependent on the stages of development (e.g., regulation of IGFBP-3 and -4) and some remain similar trends at all stages (e.g., regulation of IGF-I and the three receptors)...
  6. ncbi Glucocorticoids act directly on osteoblasts and osteocytes to induce their apoptosis and reduce bone formation and strength
    CHARLES A O'BRIEN
    Division of Endocrinology and Metabolism, Center for Osteoporosis and Metabolic Bone Diseases, Department of Internal Medicine, Central Arkansas Veterans Healthcare System, University of Arkansas for Medical Sciences, Little Rock 72205 7199, USA
    Endocrinology 145:1835-41. 2004
    ..Furthermore, our results suggest that glucocorticoid-induced loss of bone strength results in part from increased death of osteocytes, independent of bone loss...
  7. pmc Prevention and mitigation of acute death of mice after abdominal irradiation by the antioxidant N-acetyl-cysteine (NAC)
    Dan Jia
    Department of Radiation Oncology, University of Arkansas for Medical Sciences College of Medicine, Little Rock, Arkansas 72205, USA
    Radiat Res 173:579-89. 2010
    ..Our data establish a central role for abscopal stimulation of bone marrow ROS in acute death in mice after abdominal irradiation...