Li Li Ji

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi Role of free radicals and antioxidant signaling in skeletal muscle health and pathology
    Li Li Ji
    University of Wisconsin Madison, Madison, WI 53706, USA
    Infect Disord Drug Targets 9:428-44. 2009
  2. ncbi Antioxidant signaling in skeletal muscle: a brief review
    Li Li Ji
    The Biodynamics Laboratory, University of Wisconsin Madison, Madison, WI 53706, USA
    Exp Gerontol 42:582-93. 2007
  3. pmc Exercise-induced hormesis may help healthy aging
    Li Li Ji
    The Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin Madison, 2000 Observatory Drive, Madison, WI 53706, USA
    Dose Response 8:73-9. 2010
  4. ncbi Aging, exercise, and phytochemicals: promises and pitfalls
    Li Li Ji
    Department of Kinesiology and Nutritional Sciences, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Ann N Y Acad Sci 1019:453-61. 2004
  5. ncbi Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle
    L L Ji
    Department of Kinesiology, University of Wisconsin, Madison, Wisconsin, USA
    FASEB J 18:1499-506. 2004
  6. doi Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling
    Li Li Ji
    The Biodynamics Laboratory, University of Wisconsin Madison, 2000 Observatory Drive, Madison, WI 53706, USA
    Free Radic Biol Med 44:142-52. 2008
  7. ncbi Role of nuclear factor kappaB and mitogen-activated protein kinase signaling in exercise-induced antioxidant enzyme adaptation
    Li Li Ji
    The Biodynamics Laboratory, Department of Kinesiology, 2000 Observatory Drive, University of Wisconsin Madison, Madison, WI 53706 1189, USA
    Appl Physiol Nutr Metab 32:930-5. 2007
  8. ncbi Exercise and hormesis: activation of cellular antioxidant signaling pathway
    Li Li Ji
    University of Wisconsin Madison, USA
    Ann N Y Acad Sci 1067:425-35. 2006
  9. ncbi Chronic ginseng consumption attenuates age-associated oxidative stress in rats
    Ying Fu
    Department of Kinesiology and Nutritional Science, University of Wisconsin Madison, Madison, WI 53706, USA
    J Nutr 133:3603-9. 2003
  10. doi Exercise activation of muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling is redox sensitive
    Chounghun Kang
    The Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin at Madison, Madison, WI 53706, USA
    Free Radic Biol Med 47:1394-400. 2009

Collaborators

Detail Information

Publications32

  1. ncbi Role of free radicals and antioxidant signaling in skeletal muscle health and pathology
    Li Li Ji
    University of Wisconsin Madison, Madison, WI 53706, USA
    Infect Disord Drug Targets 9:428-44. 2009
    ..Given the physiological role of skeletal muscle we will emphasize the importance of physical exercise in promoting cellular antioxidant defense and its benefits in the maintenance of muscle health...
  2. ncbi Antioxidant signaling in skeletal muscle: a brief review
    Li Li Ji
    The Biodynamics Laboratory, University of Wisconsin Madison, Madison, WI 53706, USA
    Exp Gerontol 42:582-93. 2007
    ..This mini-review will discuss the main mechanisms and gene targets for these antioxidant signaling pathways during exercise, inflammation and aging...
  3. pmc Exercise-induced hormesis may help healthy aging
    Li Li Ji
    The Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin Madison, 2000 Observatory Drive, Madison, WI 53706, USA
    Dose Response 8:73-9. 2010
    ....
  4. ncbi Aging, exercise, and phytochemicals: promises and pitfalls
    Li Li Ji
    Department of Kinesiology and Nutritional Sciences, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Ann N Y Acad Sci 1019:453-61. 2004
    ..However, due to their structural and chemical diversity and complexity, many of the benefits as well as potential adverse effects remain to be examined...
  5. ncbi Acute exercise activates nuclear factor (NF)-kappaB signaling pathway in rat skeletal muscle
    L L Ji
    Department of Kinesiology, University of Wisconsin, Madison, Wisconsin, USA
    FASEB J 18:1499-506. 2004
    ..The cascade of intracellular events may be the overture to elevated gene expression of manganese superoxide dismutase reported earlier (Pfluegers Arch. 442, 426-434, 2001)...
  6. doi Modulation of skeletal muscle antioxidant defense by exercise: Role of redox signaling
    Li Li Ji
    The Biodynamics Laboratory, University of Wisconsin Madison, 2000 Observatory Drive, Madison, WI 53706, USA
    Free Radic Biol Med 44:142-52. 2008
    ..This mini-review will discuss the main mechanisms and gene targets for these signaling pathways during exercise and the biological significance of the adaptation...
  7. ncbi Role of nuclear factor kappaB and mitogen-activated protein kinase signaling in exercise-induced antioxidant enzyme adaptation
    Li Li Ji
    The Biodynamics Laboratory, Department of Kinesiology, 2000 Observatory Drive, University of Wisconsin Madison, Madison, WI 53706 1189, USA
    Appl Physiol Nutr Metab 32:930-5. 2007
    ..This scenario explains why animals and humans involved in exercise training have demonstrated increased resistance to oxidative damage under a wide range of physiological and pathological stresses...
  8. ncbi Exercise and hormesis: activation of cellular antioxidant signaling pathway
    Li Li Ji
    University of Wisconsin Madison, USA
    Ann N Y Acad Sci 1067:425-35. 2006
    ..Our data suggest that ROS may serve as messenger molecules to activate adaptive responses through these redox-sensitive signaling pathways to maintain cellular oxidant-antioxidant homeostasis during exercise...
  9. ncbi Chronic ginseng consumption attenuates age-associated oxidative stress in rats
    Ying Fu
    Department of Kinesiology and Nutritional Science, University of Wisconsin Madison, Madison, WI 53706, USA
    J Nutr 133:3603-9. 2003
    ..These protective effects are explained in part by elevated antioxidant enzyme activities in the various tissues...
  10. doi Exercise activation of muscle peroxisome proliferator-activated receptor-gamma coactivator-1alpha signaling is redox sensitive
    Chounghun Kang
    The Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin at Madison, Madison, WI 53706, USA
    Free Radic Biol Med 47:1394-400. 2009
    ..The data indicate that contraction-activated PGC-1alpha signaling pathways in skeletal muscle are redox sensitive and that nonmitochondrial ROS play an important role in stimulating mitochondrial biogenesis...
  11. ncbi American ginseng supplementation induces an oxidative stress in postmenopausal women
    Jonathan R Dickman
    Department of Kinesiology, University of Wisconsin Madison, Madison, Wisconsin, USA
    J Am Coll Nutr 28:219-28. 2009
    ..To determine whether American ginseng (Panax Quinquefolium) confers antioxidant protection to postmenopausal women at rest and after a mild aerobic exercise session...
  12. ncbi Exercise-induced modulation of antioxidant defense
    Li Li Ji
    Department of Kinesiology, Interdisciplinary Nutritional Science, and Institute on Aging, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Ann N Y Acad Sci 959:82-92. 2002
    ..Aging does not abolish but seems to attenuate training adaptations of antioxidant enzymes. Thus, for senescent muscle, training should be assisted with supplementation of exogenous antioxidants to research the optimal level of defense...
  13. doi Avenanthramides are bioavailable and accumulate in hepatic, cardiac, and skeletal muscle tissue following oral gavage in rats
    Ryan T Koenig
    Department of Kinesiology, University of Wisconsin Madison, 2000 Observatory Drive, Madison, Wisconsin 53706, USA
    J Agric Food Chem 59:6438-43. 2011
    ..With AVA remaining in the organs for up to 12 h, it seems possible to maintain an increased level of AVA in the rat via repeated feedings...
  14. ncbi M1/70 attenuates blood-borne neutrophil oxidants, activation, and myofiber damage following stretch injury
    S Brickson
    Department of Kinesiology, University of Wisconsin Madison, Madison, WI 53706, USA
    J Appl Physiol (1985) 95:969-76. 2003
    ..attenuates neutrophil activation status, 3). increases plasma IL-8 concentration, and 4). minimizes myofiber damage 24 h postmuscle stretch injury...
  15. ncbi Exercise at old age: does it increase or alleviate oxidative stress?
    L L Ji
    Department of Kinesiology, Nutritional Science, and Institute on Aging, University of Wisconsin Madison, 53706, USA
    Ann N Y Acad Sci 928:236-47. 2001
    ....
  16. ncbi Oxidant production and immune response after stretch injury in skeletal muscle
    S Brickson
    Department of Family Medicine, University of Wisconsin Medical School, 621 Science Drive, Madison, WI 53711, USA
    Med Sci Sports Exerc 33:2010-5. 2001
    ..The increase in oxidant production at 4 h may be caused by an increase in activated neutrophils, whereas XO activity may contribute to oxidant generation at 24 h...
  17. ncbi Aged rat hearts are not more susceptible to ischemia-reperfusion injury in vivo: role of glutathione
    S Leichtweis
    Department of Kinesiology and Nutritional Science, University of Wisconsin, Madison, WI 53706, USA
    Mech Ageing Dev 122:503-18. 2001
    ..It is concluded that senescent hearts with intact circulatory and neural inputs are not more susceptible to I-R injury than adult hearts during myocardial I-R, partly because they have a greater GSH antioxidant protection...
  18. ncbi Antioxidants and oxidative stress in exercise
    L L Ji
    Department of Kinesiology, Interdepartmental Program of Nutritional Sciences, and Institute on Aging, University of Wisconsin Madison, 53706, USA
    Proc Soc Exp Biol Med 222:283-92. 1999
    ..The delicate balance between pro-oxidants and antioxidants suggests that supplementation of antioxidants may be desirable for physically active individuals under certain physiological conditions by providing a larger protective margin...
  19. ncbi Oxidative stress and aging. Role of exercise and its influences on antioxidant systems
    L L Ji
    Department of Kinesiology and Nutritional Sciences, University of Wisconsin Madison 53706, USA
    Ann N Y Acad Sci 854:102-17. 1998
    ....
  20. ncbi Exercise training attenuates aging-associated mitochondrial dysfunction in rat skeletal muscle: role of PGC-1α
    Chounghun Kang
    The Laboratory of Physiological Hygiene and Exercise Science, School of Kinesiology, University of Minnesota at Twin Cities, Minneapolis, MN 55455, USA The Biodynamics Laboratory, Department of Kinesiology, University of Wisconsin Madison, Madison, WI 53706, USA
    Exp Gerontol 48:1343-50. 2013
    ..These data indicate that endurance training can attenuate aging-associated decline in mitochondrial protein synthesis in skeletal muscle partly due to upregulation of PGC-1α signaling...
  21. pmc Avenanthramide supplementation attenuates exercise-induced inflammation in postmenopausal women
    Ryan Koenig
    Department of Kinesiology, University of Wisconsin Madison, Madison, WI 53706, USA
    Nutr J 13:21. 2014
    ..Thus, chronic AVA supplementation decreased systemic and DW-induced inflammation and increased blood-borne antioxidant defense in postmenopausal women. ..
  22. ncbi Training down-regulates fatty acid synthase and body fat in obese Zucker rats
    Russell G Fiebig
    Interdepartmental Graduate Program in Nutritional Science, and Department of Kinesiology, University of Wisconsin Madison, Madison, WI, USA
    Med Sci Sports Exerc 34:1106-14. 2002
    ..The purpose of this study was to investigate whether chronic exercise training attenuates fatty acid synthase, the rate-limiting enzyme for hepatic lipogenesis, and the accumulation of body fat by using obese Zucker rats (OZR) as a model...
  23. ncbi Sleep deprivation and cellular responses to oxidative stress
    Anupama Gopalakrishnan
    Department of Psychiatry, University of Wisconsin, Madison 53719, USA
    Sleep 27:27-35. 2004
    ....
  24. ncbi Growth performance and muscle oxidation in rats fed increasing amounts of high-tannin sorghum
    R E Larraín
    Department of Animal Sciences, University of Wisconsin, Madison 53706, USA
    J Anim Sci 85:3276-84. 2007
    ..Feeding HTS reduced markers of protein oxidation in rat muscle after 6 d of refrigerated storage. If similar results are observed in animals such as swine or cattle, the use of HTS as animal feed should be reassessed...
  25. ncbi Betalains, phase II enzyme-inducing components from red beetroot (Beta vulgaris L.) extracts
    Chen Hsien Lee
    Department of Food Science, University of Wisconsin, Madison 53706, USA
    Nutr Cancer 53:91-103. 2005
    ..Subsequent to the animal studies, betanin was isolated in pure form, identified by MS analysis, and confirmed to be QR inducers in the bioassay...
  26. ncbi Glutathione supplementation and training increases myocardial resistance to ischemia-reperfusion in vivo
    P R Ramires
    Interdisciplinary Nutritional Science Program, Department of Kinesiology, University of Wisconsin, Madison, Wisconsin 53706, USA
    Am J Physiol Heart Circ Physiol 281:H679-88. 2001
    ....
  27. doi Interplay of oxidants and antioxidants during exercise: implications for muscle health
    Maria Carmen Gomez-Cabrera
    University of Valencia, Valencia, Spain
    Phys Sportsmed 37:116-23. 2009
    ..Adaptation of muscle to increased oxidative stress and the potential mechanisms involved will be highlighted. The role of redox-controlled cell signaling in skeletal muscle health and function is also described...
  28. ncbi Reduced oxidative power but unchanged antioxidative capacity in skeletal muscle from aged humans
    Michail Tonkonogi
    Department of Physiology and Pharmacology, Karolinska Institutet, Box 5626, 114 86, Stockholm, Sweden
    Pflugers Arch 446:261-9. 2003
    ..It is concluded that aging is associated with mitochondrial dysfunction, which appears to be unrelated to reduced physical activity. The hypothesis of increased oxidative stress in aged muscle could not be confirmed in this study...
  29. ncbi Effects of endurance training on three superoxide dismutase isoenzymes in human plasma
    Tomomi Ookawara
    Department of Biochemistry, Hyogo College of Medicine, 1 1 Mukogawa cho, Nishinomiya, Hyogo 663 8501, Japan
    Free Radic Res 37:713-9. 2003
    ..The results also suggest the possibility of plasma EC-SOD assay as a new index of endurance training...
  30. doi Regulation of mitochondrial uncoupling respiration during exercise in rat heart: role of reactive oxygen species (ROS) and uncoupling protein 2
    Hai Bo
    Tianjin Research Institute of Sports Medicine and Department of Health and Exercise Science, Tianjin University of Sport, Tianjin 300381, China
    Free Radic Biol Med 44:1373-81. 2008
    ....
  31. pmc Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats
    Mari Carmen Gomez-Cabrera
    Catholic University of Valencia, Spain
    J Physiol 567:113-20. 2005
    ....
  32. ncbi Changes in nitric oxide and inducible nitric oxide synthase following stretch-induced injury to the tibialis anterior muscle of rabbit
    Tomonobu Sakurai
    Department of Kinesiology, Tokyo Metropolitan University, Tokyo, Japan
    Jpn J Physiol 55:101-7. 2005
    ..05) and at 48 h (p < 0.01) in injured versus sham-operated muscles. These results suggest that NO may play an active role during the postinjury recovery of skeletal muscle modulated by iNOS expression...