Research Topics
Species | J V JesterSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
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Detail Information
Publications
The cellular basis of corneal transparency: evidence for 'corneal crystallins'J V Jester
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
J Cell Sci 112:613-22. 1999..Our results suggest that corneal cells, like lens cells, may preferentially express water-soluble proteins, often enzymes, for controlling their optical properties...
Extent of initial corneal injury as a basis for alternative eye irritation testsJ V Jester
Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX, USA
Toxicol In Vitro 15:115-30. 2001..We believe that this approach may ultimately lead to an alternative assay to replace the use of animals in ocular irritation testing...
Quantitative characterization of acid- and alkali-induced corneal injury in the low-volume eye testJ V Jester
Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 75235 9057, USA
Toxicol Pathol 28:668-78. 2000..To our knowledge, this is the first time that the ocular irritation potential for different types of materials (acid/alkali, surfactants) has been shown to be primarily dependent on the initial area and depth of injury...
Effects of low and hyper Dk rigid gas permeable contact lenses on Bcl-2 expression and apoptosis in the rabbit corneal epitheliumK Yamamoto
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, 75390-9057, USA
CLAO J 27:137-43. 2001..Taken together, these findings may explain why contact lens wear reduces surface cell exfoliation as previously reported in human studies...
Bcl-2 expression in the human corneaK Yamamoto
The Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-9057, USA
Exp Eye Res 73:247-55. 2001..Taken together, these findings suggest that Bcl-2 protein may play a critical role in modulating apoptotic cell desquamation in the human corneal epithelium...
Effects of rigid and soft contact lens daily wear on corneal epithelium, tear lactate dehydrogenase, and bacterial binding to exfoliated epithelial cellsP M Ladage
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, 75390-9057, USA
Ophthalmology 108:1279-88. 2001..Taken together, these findings suggest for the first time both an oxygen effect as well as a difference between soft and rigid lens types on PA binding in DW...
Proliferation rate of rabbit corneal epithelium during overnight rigid contact lens wearP M Ladage
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, 75039-9057, USA
Invest Ophthalmol Vis Sci 42:2804-12. 2001..RGP lens wear significantly altered the homeostatic proliferation pattern of the epithelium with the low-Dk/t lens having the most dramatic effect. RGP contact lens wear appears to stimulate proliferation of keratocytes...
Corneal haze after photorefractive keratectomy using different epithelial removal techniques: mechanical debridement versus laser scrapeY G Lee
Department of Ophthalmology, University of Texas, Southwestern Medical Center at Dallas, Dallas, Texas, USA
Ophthalmology 108:112-20. 2001..Power = 0.96). CONCLUSIONS: There is no significant difference in the corneal wound healing response between mechanical epithelial debridement versus laser-scrape technique in human myopic eyes undergoing PRK...
The spatial organization of apical junctional complex-associated proteins in feline and human corneal endotheliumW M Petroll
Department of Ophthalmology, University of Texas Southwestern Medical Center, Dallas 75235 9057, USA
Curr Eye Res 18:10-9. 1999..The goal of this study is to identify and determine the spatial organization of several major AJC-associated proteins in normal human and feline corneal endothelium...
Stress fiber formation is required for matrix reorganization in a corneal myofibroblast cell lineP K Mar
Department of Ophthalmology, University of Texas, Southwestern Medical Center at Dallas, Dallas, TX 75235-9057, USA
Exp Eye Res 72:455-66. 2001....
Specular microscopy, confocal microscopy, and ultrasound biomicroscopy: diagnostic tools of the past quarter centuryH D Cavanagh
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, USA
Cornea 19:712-22. 2000..To identify, characterize, and illustrate the most important past and future potential contributions of specular, confocal, and ultrasound biomicroscopy to clinical diagnosis and research applications in the cornea from the past 25 years...
Measurement of corneal sublayer thickness and transparency in transgenic mice with altered corneal clarity using in vivo confocal microscopyJ V Jester
Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9057, USA
Vision Res 41:1283-90. 2001..Our findings suggest that in vivo confocal microscopy can be used to identify the effects of transgene expression on mouse corneal transparency...
Epitope variability of Bcl-2 immunolocalization in the human corneal epitheliumK Yamamoto
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, 75390-9057, USA
CLAO J 27:221-4. 2001....
Corneal stromal wound healing in refractive surgery: the role of myofibroblastsJ V Jester
Department of Ophthalmology, The University of Texas Southwestern Medical Center at Dallas, 75235-9057, USA
Prog Retin Eye Res 18:311-56. 1999....
Hydrogen peroxide causes mitochondrial DNA damage in corneal epithelial cellsShari R Atilano
Department of Ophthalmology, University of California, Irvine Medical Center, Irvine, CA 92868, USA
Cornea 28:426-33. 2009..In addition, we compared the integrity of mtDNA found in epithelial cells isolated from keratoconus (KC) and normal (NL) corneas...
Corneal opacity in lumican-null mice: defects in collagen fibril structure and packing in the posterior stromaS Chakravarti
Department of Medicine and Genetics, Case Western Reserve University and University Hospitals of Cleveland, Ohio, USA
Invest Ophthalmol Vis Sci 41:3365-73. 2000..The purpose of the present study was to analyze the loss of transparency quantitatively and to define the associated corneal collagen fibril and stromal defects...
Pathology of ocular irritation with bleaching agents in the rabbit low-volume eye testJ K Maurer
The Procter and Gamble Co, Cincinnati, Ohio, USA
Toxicol Pathol 29:308-19. 2001....
Organization of junctional proteins in proliferating cat corneal endothelium during wound healingW M Petroll
The University of Texas Southwestern Medical Center, Dallas 75235-9057, USA
Cornea 20:73-80. 2001..CONCLUSIONS: After in vivo scrape injury, proliferation is limited temporally and spatially to spreading endothelial cells within the wound. Cell junctional connections appear to be maintained in actively cycling cells during healing...
Pathology of ocular irritation with acetone, cyclohexanol, parafluoroaniline, and formaldehyde in the rabbit low-volume eye testJ K Maurer
The Procter and Gamble Co, Cincinnati, Ohio, USA
Toxicol Pathol 29:187-99. 2001..We believe this approach can be applied to developing alternative assays based on injury to ex vivo eyes or injury to an in vitro corneal equivalent system...
