D M Jensen

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Endoscopic diagnosis and treatment of watermelon stomach
    D M Jensen
    UCLA CURE, Veterans Administration Medical Center, 11301 Wilshire Boulevard, Building 115, Room 318, Los Angeles, CA 90073, USA
    Endoscopy 36:640-7. 2004
  2. ncbi request reprint Randomized double-blind studies of polysaccharide gel compared with glue and other agents for hemostasis of large veins and bleeding canine esophageal or gastric varices
    Dennis M Jensen
    University of California, Los Angeles School of Medicine, CURE Digestive Disease Research Center, and the VA Greater Los Angeles Healthcare System, 90073 1003, USA
    J Trauma 57:S33-7. 2004
  3. ncbi request reprint Randomized trial of medical or endoscopic therapy to prevent recurrent ulcer hemorrhage in patients with adherent clots
    Dennis M Jensen
    CURE Digestive Disease Research Center, UCLA School of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
    Gastroenterology 123:407-13. 2002
  4. ncbi request reprint Clots and spots on ulcers: why and how to treat
    D M Jensen
    UCLA CURE Digestive Disease Research Center, Bldg 115, Room 318, VA Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073 1003, USA
    Langenbecks Arch Surg 386:82-7. 2001
  5. ncbi request reprint Endoscopic screening for varices in cirrhosis: findings, implications, and outcomes
    Dennis M Jensen
    CURE Digestive Diseases Research Center, University of California Los Angeles School of Medicine, Los Angeles, CA, USA
    Gastroenterology 122:1620-30. 2002
  6. ncbi request reprint The economic impact of esophageal variceal hemorrhage: cost-effectiveness implications of endoscopic therapy
    I M Gralnek
    University of California, Los Angeles UCLA School of Medicine, Center for the Health Sciences, Department of Medicine, Division of Digestive Diseases, Los Angeles, CA 90095 1684, USA
    Hepatology 29:44-50. 1999
  7. pmc Severe upper gastrointestinal hemorrhage from linear gastric ulcers in large hiatal hernias: a large prospective case series of Cameron ulcers
    M Camus
    CURE Hemostasis Research Group, CURE Digestive Diseases Research Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States
    Endoscopy 45:397-400. 2013
  8. ncbi request reprint A randomized prospective study of endoscopic bipolar electrocoagulation and heater probe treatment of chronic rectal bleeding from radiation telangiectasia
    D M Jensen
    CURE Digestive Disease Research Center, UCLA Center for the Health Sciences 90095 1684, USA
    Gastrointest Endosc 45:20-5. 1997
  9. ncbi request reprint Endoscopic treatment outcomes in watermelon stomach patients with and without portal hypertension
    G S Dulai
    Center for Ulcer Research and Education, Digestive Disease Research Center, Center for the Study of Digestive Healthcare Quality and Outcomes, University of California at Los Angeles School of Medicine, Los Angeles, California, USA
    Endoscopy 36:68-72. 2004
  10. ncbi request reprint Randomized controlled study of 3 different types of hemoclips for hemostasis of bleeding canine acute gastric ulcers
    Dennis M Jensen
    CURE Hemostasis Research Group, CURE Digestive Diseases Research Center, Bldg 115, Rm 318, VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA 90073 1003, USA
    Gastrointest Endosc 64:768-73. 2006

Research Grants

  1. GASTROENTEROLOGY
    Dennis Jensen; Fiscal Year: 2007
  2. UGI Hemorrhage and Barrett's Epithelium
    Dennis Jensen; Fiscal Year: 2007

Collaborators

Detail Information

Publications37

  1. ncbi request reprint Endoscopic diagnosis and treatment of watermelon stomach
    D M Jensen
    UCLA CURE, Veterans Administration Medical Center, 11301 Wilshire Boulevard, Building 115, Room 318, Los Angeles, CA 90073, USA
    Endoscopy 36:640-7. 2004
  2. ncbi request reprint Randomized double-blind studies of polysaccharide gel compared with glue and other agents for hemostasis of large veins and bleeding canine esophageal or gastric varices
    Dennis M Jensen
    University of California, Los Angeles School of Medicine, CURE Digestive Disease Research Center, and the VA Greater Los Angeles Healthcare System, 90073 1003, USA
    J Trauma 57:S33-7. 2004
    ..The safety and efficacy of poly-N-acetyl glucosamine (p-GlcNAc) gels were compared with standard agents in three different dog studies to assess abdominal venous collaterals, bleeding esophageal varices, and bleeding gastric varices...
  3. ncbi request reprint Randomized trial of medical or endoscopic therapy to prevent recurrent ulcer hemorrhage in patients with adherent clots
    Dennis M Jensen
    CURE Digestive Disease Research Center, UCLA School of Medicine, VA Greater Los Angeles Healthcare System, Los Angeles, California 90073, USA
    Gastroenterology 123:407-13. 2002
    ..Our purpose was to test the hypothesis that patients treated with combination endoscopic therapy would have significantly lower rebleeding rates than those treated with medical therapy...
  4. ncbi request reprint Clots and spots on ulcers: why and how to treat
    D M Jensen
    UCLA CURE Digestive Disease Research Center, Bldg 115, Room 318, VA Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Los Angeles, CA 90073 1003, USA
    Langenbecks Arch Surg 386:82-7. 2001
    ..Clinical presentation and comorbidity and the endoscopic appearance of the ulcer (i.e., stigmata of hemorrhage) of patients with UGI bleeding are used to determine the subsequent level of care (e.g., discharge or ward or intensive care)...
  5. ncbi request reprint Endoscopic screening for varices in cirrhosis: findings, implications, and outcomes
    Dennis M Jensen
    CURE Digestive Diseases Research Center, University of California Los Angeles School of Medicine, Los Angeles, CA, USA
    Gastroenterology 122:1620-30. 2002
    ..For low or very low risk cirrhotic patients-those found to have no varices or small varices without stigmata-repeat endoscopy is recommended because screening for progression may be warranted in 2 or more years...
  6. ncbi request reprint The economic impact of esophageal variceal hemorrhage: cost-effectiveness implications of endoscopic therapy
    I M Gralnek
    University of California, Los Angeles UCLA School of Medicine, Center for the Health Sciences, Department of Medicine, Division of Digestive Diseases, Los Angeles, CA 90095 1684, USA
    Hepatology 29:44-50. 1999
    ..Further studies comparing costs and resource utilization in this patient population are needed...
  7. pmc Severe upper gastrointestinal hemorrhage from linear gastric ulcers in large hiatal hernias: a large prospective case series of Cameron ulcers
    M Camus
    CURE Hemostasis Research Group, CURE Digestive Diseases Research Center, David Geffen School of Medicine at UCLA, Los Angeles, California, United States
    Endoscopy 45:397-400. 2013
    ..Cameron ulcers in large hiatal hernias are an uncommon cause of severe upper GIH. The choice of medical vs. surgical therapy should be individualized...
  8. ncbi request reprint A randomized prospective study of endoscopic bipolar electrocoagulation and heater probe treatment of chronic rectal bleeding from radiation telangiectasia
    D M Jensen
    CURE Digestive Disease Research Center, UCLA Center for the Health Sciences 90095 1684, USA
    Gastrointest Endosc 45:20-5. 1997
    ....
  9. ncbi request reprint Endoscopic treatment outcomes in watermelon stomach patients with and without portal hypertension
    G S Dulai
    Center for Ulcer Research and Education, Digestive Disease Research Center, Center for the Study of Digestive Healthcare Quality and Outcomes, University of California at Los Angeles School of Medicine, Los Angeles, California, USA
    Endoscopy 36:68-72. 2004
    ..The aims of this study were to describe the endoscopic appearance and treatment outcomes in watermelon stomach patients with and without portal hypertension...
  10. ncbi request reprint Randomized controlled study of 3 different types of hemoclips for hemostasis of bleeding canine acute gastric ulcers
    Dennis M Jensen
    CURE Hemostasis Research Group, CURE Digestive Diseases Research Center, Bldg 115, Rm 318, VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Los Angeles, CA 90073 1003, USA
    Gastrointest Endosc 64:768-73. 2006
    ..No comparative data have been reported on ease of clip placement, hemostasis efficacy, or clip retention rates on bleeding ulcers...
  11. ncbi request reprint Urgent colonoscopy for the diagnosis and treatment of severe diverticular hemorrhage
    D M Jensen
    Digestive Disease Research Center, University of California at Los Angeles Center for the Health Sciences, and the Veterans Affairs Greater Los Angeles Healthcare System, 90073 1003, USA
    N Engl J Med 342:78-82. 2000
    ..Although endoscopy is often used to diagnose and treat acute upper gastrointestinal bleeding, its role in the management of diverticulosis and lower gastrointestinal bleeding is uncertain...
  12. ncbi request reprint Therapeutic endoscopy for nonvariceal gastrointestinal bleeding
    T J Savides
    Department of Clinical Medicine, University of California, San Diego, USA
    Gastroenterol Clin North Am 29:465-87, vii. 2000
    ..Recommendations for endoscopic techniques are based on the results of UCLA-CURE hemostasis studies...
  13. ncbi request reprint The short-term medical management of non-variceal upper gastrointestinal bleeding
    Thomas O G Kovacs
    CURE Digestive Disease Research Center, VA Greater Los Angeles Healthcare System, Los Angeles, California 90073 1003, USA
    Drugs 68:2105-11. 2008
    ..Medical management with proton pump inhibitors is not a substitute for appropriate endoscopic therapy for patients with UGI bleeding and high-risk ulcer stigmata...
  14. ncbi request reprint Endoscopic treatment of ulcer bleeding
    Thomas O G Kovacs
    Thomas O G Kovacs, MD CURE Digestive Diseases Research Center, VA Greater Los Angeles Healthcare System, 11301 Wilshire Boulevard, Building 115, Room 212, Los Angeles, CA 90073 1003, USA
    Curr Treat Options Gastroenterol 10:143-8. 2007
    ..Effective endoscopic hemostasis of ulcer bleeding can significantly improve outcomes by reducing rebleeding, transfusion requirement, and need for surgery, as well as reduce cost of medical care...
  15. ncbi request reprint Randomized study comparing banding and propranolol to prevent initial variceal hemorrhage in cirrhotics with high-risk esophageal varices
    Rome Jutabha
    Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Gastroenterology 128:870-81. 2005
    ..Standard care for prevention of first esophageal variceal hemorrhage is beta-blockade, but this may be ineffective or unsafe. Our purpose was to compare endoscopic banding with propranolol for prevention of first variceal hemorrhage...
  16. ncbi request reprint Severe gastrointestinal bleeding of obscure origin
    Gareth S Dulai
    Division of Gastroenterology, CURE Digestive Diseases Research Center, Center for the Study of Digestive Healthcare Quality and Outcomes, Greater Los Angeles Veterans Administration Healthcare System, Los Angeles, CA 90073, USA
    Gastrointest Endosc Clin N Am 14:101-13. 2004
  17. ncbi request reprint Recent advances in the endoscopic diagnosis and therapy of upper gastrointestinal, small intestinal, and colonic bleeding
    Thomas O G Kovacs
    Division of Digestive Diseases, Department of Medicine, University of California at Los Angeles, School of Medicine, CURE Digestive Diseases Research Center, VA Greater Los Angeles Healthcare System, Los Angeles, CA, USA
    Med Clin North Am 86:1319-56. 2002
    ....
  18. ncbi request reprint Spots and clots - leave them or treat them? Why and how to treat
    D M Jensen
    UCLA School of Medicine, Los Angeles, California 90024 1684, USA
    Can J Gastroenterol 13:413-5. 1999
    ..The clinical condition and the endoscopic appearance of the ulcer (ie, stigmata of hemorrhage) of the patient with upper gastrointestinal bleeding are used to determine the subsequent level of care (discharge, ward or intensive care)...
  19. ncbi request reprint Continuous infusion of pantoprazole versus ranitidine for prevention of ulcer rebleeding: a U.S. multicenter randomized, double-blind study
    Dennis M Jensen
    David Geffen School of Medicine at UCLA and CURE Digestive Diseases Research Center, Los Angeles, California 90073, USA
    Am J Gastroenterol 101:1991-9; quiz 2170. 2006
    ..Our hypothesis was that ulcer rebleeding with IV pantoprazole (PAN) would be lower than with IV ranitidine (RAN)...
  20. pmc Hemoclipping of chronic canine ulcers: a randomized, prospective study of initial deployment success, clip retention rates, and ulcer healing
    Dennis M Jensen
    Center for Ulcer Research and Education, Hemostasis Research Group, CURE Digestive Diseases Research Center, VA Greater Los Angeles Healthcare System, and David Geffen School of Medicine at UCLA, Los Angeles, California CA 90073 1003, USA
    Gastrointest Endosc 70:969-75. 2009
    ..No previous reports have compared success rates of clip deployment onto bases of chronic gastric ulcers (GUs), clip retention rates, or their influence on ulcer healing...
  21. ncbi request reprint Push enteroscopy for recurrent gastrointestinal hemorrhage due to jejunal anastomotic varices: a case report and review of the literature
    S J Tang
    Division of Digestive Diseases, Center for Health Sciences, UCLA School of Medicine, Los Angeles, California
    Endoscopy 34:735-7. 2002
    ..Although the treatment of segmental varices has been surgical resection, for patients with overt systemic portal hypertension, a transjugular intrahepatic portal-systemic shunt or a decompressive shunting procedure are recommended...
  22. ncbi request reprint Definitive therapy for internal hemorrhoids--new opportunities and options
    Gordon V Ohning
    David Geffen School of Medicine at UCLA, Greater Los Angeles VA Healthcare Center, Center for Ulcer Research and Education CURE Digestive Diseases Research Center, Los Angeles, California, USA
    Rev Gastroenterol Disord 9:16-26. 2009
    ....
  23. ncbi request reprint Gastric acid inhibition in the treatment of peptic ulcer hemorrhage
    Kevin A Ghassemi
    Center for Ulcer Research and Education, Digestive Diseases Research Center, VA Greater Los Angeles, Healthcare System, Building 115, Room 318, Los Angeles, CA 90073 1003, USA
    Curr Gastroenterol Rep 11:462-9. 2009
    ..High-dose oral PPIs may be as effective as intravenous infusion in achieving positive clinical outcomes, but this has not been documented by randomized studies and its cost-effectiveness is unclear...
  24. ncbi request reprint Current diagnosis and treatment of severe obscure GI hemorrhage
    Dennis M Jensen
    UCLA School of Medicine, Los Angeles, California, USA
    Gastrointest Endosc 58:256-66. 2003
  25. pmc The significance of gastric and duodenal histological ischemia reported on endoscopic biopsy
    J Herman
    Center of Ulcer Research and Education, Digestive Diseases Research Center, Los Angeles, California, USA
    Endoscopy 43:365-8. 2011
    ..Computed tomography scanning was frequently used (12 cases, 86 %), but led to an underlying diagnosis in only three cases. In our series, patients with underlying vascular pathology have substantial 6-month mortality (29 %)...
  26. ncbi request reprint Dysplasia and risk of further neoplastic progression in a regional Veterans Administration Barrett's cohort
    Gareth S Dulai
    Greater Los Angeles Veterans Administration Healthcare System, Department of Medicine, Division of Gastroenterology, UCLA School of Medicine, Los Angeles, CA 90073, USA
    Am J Gastroenterol 100:775-83. 2005
    ..Our aims were to estimate and compare the risk of progression to high-grade dysplasia or cancer in groups of Barrett's patients stratified by baseline dysplasia status...
  27. pmc Randomized prospective study of endoscopic rubber band ligation compared with bipolar coagulation for chronically bleeding internal hemorrhoids
    Rome Jutabha
    David Geffen School of Medicine at UCLA, Greater Los Angeles VA Healthcare Center, Los Angeles, California 90073 1003, USA
    Am J Gastroenterol 104:2057-64. 2009
    ....
  28. ncbi request reprint Endoscopic diagnosis and treatment of severe lower gastrointestinal bleeding
    Gustavo A Machicado
    UCLA Center for the Health Sciences, Veteran s Administration Greater Los Angeles Healthcare Center, Los Angeles, CA, USA
    Indian J Gastroenterol 25:S43-51. 2006
    ..Also, urgent colonoscopy after purge has been reported to be more cost-effective than elective colonoscopy or other strategies for diagnosis of severe hematochezia...
  29. doi request reprint Lower gastrointestinal events in a double-blind trial of the cyclo-oxygenase-2 selective inhibitor etoricoxib and the traditional nonsteroidal anti-inflammatory drug diclofenac
    Loren Laine
    Division of Gastrointestinal and Liver Diseases, University of Southern California, Keck School of Medicine, Los Angeles, California, USA
    Gastroenterology 135:1517-25. 2008
    ..Cyclo-oxygenase (COX)-2 selective inhibitors decrease upper GI events, but no prospective trial has prespecified assessment of lower GI clinical events...
  30. ncbi request reprint The novel use of an intravenous proton pump inhibitor in a patient with short bowel syndrome
    Shou Jiang Tang
    Division of Gastroenterology and Hepatology, VA Greater Los Angeles Healthcare System, California 90073, USA
    J Clin Gastroenterol 34:62-3. 2002
    ....
  31. ncbi request reprint Major stigmata of recent hemorrhage on rectal ulcers in patients with severe hematochezia: Endoscopic diagnosis, treatment, and outcomes
    Fasiha Kanwal
    Division of Digestive Diseases and Department of Medicine, UCLA School of Medicine, Los Angeles, California, USA
    Gastrointest Endosc 57:462-8. 2003
    ..Endoscopic diagnosis and treatment of hematochezia caused by rectal ulcers is poorly described...
  32. ncbi request reprint Where next with endoscopic ulcer hemostasis?
    Dennis M Jensen
    Am J Gastroenterol 97:2161-5. 2002
  33. ncbi request reprint Treatment of patients at high risk for recurrent bleeding from a peptic ulcer
    Dennis M Jensen
    Ann Intern Med 139:294-5. 2003
  34. ncbi request reprint Management of patients with severe hematochezia--with all current evidence available
    Dennis M Jensen
    Am J Gastroenterol 100:2403-6. 2005
    ..Meanwhile, further RCTs for patients with severe hematochezia are warranted...
  35. ncbi request reprint Endoscopic therapy versus medical therapy for bleeding peptic ulcer with adherent clot: a meta-analysis
    Charles J Kahi
    Indiana University Medical Center, and Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202, USA
    Gastroenterology 129:855-62. 2005
    ..The optimal management of bleeding peptic ulcer with adherent clot is controversial and may include endoscopic therapy or medical therapy...
  36. ncbi request reprint Randomized trial of argon plasma coagulation vs. multipolar electrocoagulation for ablation of Barrett's esophagus
    Gareth S Dulai
    Gastrointest Endosc 61:232-40. 2005
    ..No randomized comparison of ablation strategies has been published...
  37. ncbi request reprint Portal hypertensive enteropathy in a patient with polycystic liver disease: a unique endoscopic finding
    Shou Jiang Tang
    Division of Digestive Diseases, Center for Health Sciences, University of California at Los Angeles UCLA, USA
    Gastrointest Endosc 56:924-6. 2002

Research Grants4

  1. GASTROENTEROLOGY
    Dennis Jensen; Fiscal Year: 2007
    ..Continued support is needed to maintain the quality and productivity of this program which is training future academicians in digestive diseases. ..
  2. UGI Hemorrhage and Barrett's Epithelium
    Dennis Jensen; Fiscal Year: 2007
    ..This award will continue to enhance the applicant's research productivity and provide skilled mentoring for young investigators, so they can become independent patient-oriented investigators in digestive diseases. ..