Research Topics

Clark D Jeffries


Affiliation: University of North Carolina
Country: USA


  1. Jeffries C, Perkins D, Fournier M, Do K, Cuenod M, Khadimallah I, et al. Networks of blood proteins in the neuroimmunology of schizophrenia. Transl Psychiatry. 2018;8:112 pubmed publisher
    ..Thus, some correlation signals strongly predict impending conversion to a psychotic disorder and directly suggest pharmaceutical targets. ..
  2. Jeffries C, Fried H, Perkins D. Nuclear and cytoplasmic localization of neural stem cell microRNAs. RNA. 2011;17:675-86 pubmed publisher
    ..That is, in addition to the seed sequence, 3' sequence similarity criteria identify families of mature miRNAs with consistently high nuclear or cytoplasmic expression. ..
  3. Jeffries C, Ward W, Perkins D, Wright F. Discovering collectively informative descriptors from high-throughput experiments. BMC Bioinformatics. 2009;10:431 pubmed publisher
    ..As a method, BLANKET is easy to conceptualize and presents only moderate computational complexity. Many existing databases could be mined using BLANKET to suggest optimal sets of predictive descriptors. ..
  4. Jeffries C, Perkins D, Guan X. Gene processing control loops suggested by sequencing, splicing, and RNA folding. BMC Bioinformatics. 2010;11:602 pubmed publisher
    ..Beyond this example, a general procedure is needed for systematic discovery of multiple alignments of sequencing, splicing, and RNA folding data. ..
  5. Jeffries C, Fried H, Perkins D. Additional layers of gene regulatory complexity from recently discovered microRNA mechanisms. Int J Biochem Cell Biol. 2010;42:1236-42 pubmed publisher