Christopher S Jeffrey

Summary

Affiliation: University of Nevada
Country: USA

Publications

  1. doi request reprint 1,4-Diamination of cyclic dienes via a (4 + 3) cycloaddition of diaza-allyl cationic intermediates
    Christopher S Jeffrey
    Department of Chemistry, University of Nevada Reno, Reno, Nevada 89557, USA
    Org Lett 14:5764-7. 2012
  2. ncbi request reprint Generation and reactivity of aza-oxyallyl cationic intermediates: aza-[4 + 3] cycloaddition reactions for heterocycle synthesis
    Christopher S Jeffrey
    Department of Chemistry, University of Nevada Reno, Reno, Nevada 89557, USA
    J Am Chem Soc 133:7688-91. 2011
  3. pmc A hypervalent iodine-induced double annulation enables a concise synthesis of the pentacyclic core structure of the cortistatins
    Jessica L Frie
    Department of Chemistry, Princeton University, Frick Chemical Laboratory, Princeton, New Jersey 08544, USA
    Org Lett 11:5394-7. 2009
  4. doi request reprint Oxidative (3 + 2) Cycloaddition Reactions of Diaza-Oxyallyl Cationic Intermediates and Indoles for the Synthesis of Imidazoloindolines
    Devendar Anumandla
    Department of Chemistry, University of Nevada, Reno, Nevada 89557 0216, United States
    Org Lett 18:476-9. 2016
  5. doi request reprint Dearomative Indole Cycloaddition Reactions of Aza-Oxyallyl Cationic Intermediates: Modular Access to Pyrroloindolines
    Arjun Acharya
    Department of Chemistry, University of Nevada, Reno, Nevada 89557 0216, United States
    J Am Chem Soc 137:14858-60. 2015
  6. doi request reprint Oxidative 1,4-diamination of dienes using simple urea derivatives
    Devendar Anumandla
    Department of Chemistry, University of Nevada, Reno, 1664 North Virginia Street, Mail Stop No 0216, Reno, Nevada 89557, United States
    Org Lett 16:5112-5. 2014
  7. doi request reprint Antiherbivore prenylated benzoic acid derivatives from Piper kelleyi
    Christopher S Jeffrey
    Department of Chemistry, University of Nevada, Reno, Reno, Nevada 89557, United States
    J Nat Prod 77:148-53. 2014
  8. pmc Dynamic kinetic resolution during a vinylogous Payne rearrangement: a concise synthesis of the polar pharmacophoric subunit of (+)-scyphostatin
    Thomas R Hoye
    Department of Chemistry, 207 Pleasant Street, SE, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Org Lett 12:52-5. 2010

Collaborators

  • Lee A Dyer
  • Devendar Anumandla
  • Arjun Acharya
  • Thomas R Hoye
  • Jessica L Frie
  • Ryan Littlefield
  • Dorian P Nelson
  • Erik J Sorensen

Detail Information

Publications8

  1. doi request reprint 1,4-Diamination of cyclic dienes via a (4 + 3) cycloaddition of diaza-allyl cationic intermediates
    Christopher S Jeffrey
    Department of Chemistry, University of Nevada Reno, Reno, Nevada 89557, USA
    Org Lett 14:5764-7. 2012
    ..This reaction was entirely selective for diamination and provided cycloadducts in good to excellent yield...
  2. ncbi request reprint Generation and reactivity of aza-oxyallyl cationic intermediates: aza-[4 + 3] cycloaddition reactions for heterocycle synthesis
    Christopher S Jeffrey
    Department of Chemistry, University of Nevada Reno, Reno, Nevada 89557, USA
    J Am Chem Soc 133:7688-91. 2011
    ..The reaction is general to a variety of α-haloamides and is diastereoselective. Computational and experimental data suggest that an N-alkoxy substituent stabilizes the aza-oxyallyl cationic intermediate...
  3. pmc A hypervalent iodine-induced double annulation enables a concise synthesis of the pentacyclic core structure of the cortistatins
    Jessica L Frie
    Department of Chemistry, Princeton University, Frick Chemical Laboratory, Princeton, New Jersey 08544, USA
    Org Lett 11:5394-7. 2009
    ..The manner in which these ring formations were orchestrated has yielded a rather concise strategy for synthesis...
  4. doi request reprint Oxidative (3 + 2) Cycloaddition Reactions of Diaza-Oxyallyl Cationic Intermediates and Indoles for the Synthesis of Imidazoloindolines
    Devendar Anumandla
    Department of Chemistry, University of Nevada, Reno, Nevada 89557 0216, United States
    Org Lett 18:476-9. 2016
    ..The reported method is compatible with a wide variety of functional groups and directly provides unique heterocyclic scaffolds from indoles and a simple urea derivative. ..
  5. doi request reprint Dearomative Indole Cycloaddition Reactions of Aza-Oxyallyl Cationic Intermediates: Modular Access to Pyrroloindolines
    Arjun Acharya
    Department of Chemistry, University of Nevada, Reno, Nevada 89557 0216, United States
    J Am Chem Soc 137:14858-60. 2015
    ..This transformation provides rapid access to highly functionalized pyrroloindolines that are represented in large number of bioactive compounds. The natural product, physostigmine, has been concisely synthesized utilizing this method. ..
  6. doi request reprint Oxidative 1,4-diamination of dienes using simple urea derivatives
    Devendar Anumandla
    Department of Chemistry, University of Nevada, Reno, 1664 North Virginia Street, Mail Stop No 0216, Reno, Nevada 89557, United States
    Org Lett 16:5112-5. 2014
    ..The reaction is easy to perform, uses simple reagents, works with a variety of functionalized dienes, and provides unique heterocyclic products. ..
  7. doi request reprint Antiherbivore prenylated benzoic acid derivatives from Piper kelleyi
    Christopher S Jeffrey
    Department of Chemistry, University of Nevada, Reno, Reno, Nevada 89557, United States
    J Nat Prod 77:148-53. 2014
    ....
  8. pmc Dynamic kinetic resolution during a vinylogous Payne rearrangement: a concise synthesis of the polar pharmacophoric subunit of (+)-scyphostatin
    Thomas R Hoye
    Department of Chemistry, 207 Pleasant Street, SE, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Org Lett 12:52-5. 2010
    ..It was possible to kinetically resolve the mixture of 3a/b under equilibrating conditions by use of Amano PS. This DKR is additionally noteworthy because it sets four stereocenters in a single event...