DIANE JAWORSKI

Summary

Affiliation: University of Vermont
Country: USA

Publications

  1. ncbi Sexually dimorphic diet-induced insulin resistance in obese tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Avenue, HSRF 418, Burlington, Vermont 05405, USA
    Endocrinology 152:1300-13. 2011
  2. ncbi Potential regulatory relationship between the nested gene DDC8 and its host gene tissue inhibitor of metalloproteinase-2
    Diane M Jaworski
    Departments of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    Physiol Genomics 28:168-78. 2007
  3. ncbi Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression is regulated by multiple neural differentiation signals
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont, USA
    J Neurochem 98:234-47. 2006
  4. ncbi Tissue inhibitor of metalloproteinase-2(TIMP-2)-deficient mice display motor deficits
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, 05405, USA
    J Neurobiol 66:82-94. 2006
  5. ncbi Prepulse inhibition and fear-potentiated startle are altered in tissue inhibitor of metalloproteinase-2 (TIMP-2) knockout mice
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Avenue, HSRF 418, Burlington, VT 05405, USA
    Brain Res 1051:81-9. 2005
  6. ncbi Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal
    Leonor Perez-Martinez
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Neurosci 25:4917-29. 2005
  7. ncbi Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates myogenesis and beta1 integrin expression in vitro
    Gentian Lluri
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Ave, HSRF 418, Burlington, VT 05405, USA
    Exp Cell Res 314:11-24. 2008
  8. ncbi Regulation of TIMP-2, MT1-MMP, and MMP-2 expression during C2C12 differentiation
    Gentian Lluri
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Avenue, HSRF 418, Burlington, Vermont 05405, USA
    Muscle Nerve 32:492-9. 2005
  9. ncbi Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates neuromuscular junction development via a beta1 integrin-mediated mechanism
    Gentian Lluri
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Neurobiol 66:1365-77. 2006
  10. ncbi The weight loss elicited by cobalt protoporphyrin is related to decreased activity of nitric oxide synthase in the hypothalamus
    Muyao Li
    Department of Medicine, University of Vermont, C209 Given Bldg, 89 Beaumont Ave, Burlington, Vermont 05405, USA
    J Appl Physiol 100:1983-91. 2006

Research Grants

  1. Molecular Regulation of TIMP-2 in Neuron Cell Cycle
    DIANE JAWORSKI; Fiscal Year: 2007

Collaborators

Detail Information

Publications10

  1. ncbi Sexually dimorphic diet-induced insulin resistance in obese tissue inhibitor of metalloproteinase-2 (TIMP-2)-deficient mice
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Avenue, HSRF 418, Burlington, Vermont 05405, USA
    Endocrinology 152:1300-13. 2011
    ....
  2. ncbi Potential regulatory relationship between the nested gene DDC8 and its host gene tissue inhibitor of metalloproteinase-2
    Diane M Jaworski
    Departments of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    Physiol Genomics 28:168-78. 2007
    ..That TIMP-2 transcripts in wild-type brain contain DDC8 sequence suggests alternative splicing between the two genes...
  3. ncbi Tissue inhibitor of metalloproteinase-2 (TIMP-2) expression is regulated by multiple neural differentiation signals
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont, USA
    J Neurochem 98:234-47. 2006
    ..We propose that TIMP-2 represents a component of the neurogenic signaling cascade induced by mitogenic stimuli that may withdraw progenitor cells from the cell cycle permitting their terminal neuronal differentiation...
  4. ncbi Tissue inhibitor of metalloproteinase-2(TIMP-2)-deficient mice display motor deficits
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, 05405, USA
    J Neurobiol 66:82-94. 2006
    ..The tissue specificity of the nerve branching phenotype suggests the involvement of different MMPs and/or extracellular matrix molecules underlying the TIMP-2(-/-) motor phenotype...
  5. ncbi Prepulse inhibition and fear-potentiated startle are altered in tissue inhibitor of metalloproteinase-2 (TIMP-2) knockout mice
    Diane M Jaworski
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Avenue, HSRF 418, Burlington, VT 05405, USA
    Brain Res 1051:81-9. 2005
    ..This is the first report of a phenotype for the TIMP-2(-/-) mice and suggests that TIMP-2 may play a role in the synaptic plasticity underlying learning and memory...
  6. ncbi Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal
    Leonor Perez-Martinez
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Neurosci 25:4917-29. 2005
    ....
  7. ncbi Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates myogenesis and beta1 integrin expression in vitro
    Gentian Lluri
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Ave, HSRF 418, Burlington, VT 05405, USA
    Exp Cell Res 314:11-24. 2008
    ..Elucidating the role of TIMP-2 in myogenesis in vitro may lead to new therapeutic options for the use of TIMP-2 in myopathies and muscular dystrophies in vivo...
  8. ncbi Regulation of TIMP-2, MT1-MMP, and MMP-2 expression during C2C12 differentiation
    Gentian Lluri
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, 149 Beaumont Avenue, HSRF 418, Burlington, Vermont 05405, USA
    Muscle Nerve 32:492-9. 2005
    ..Elucidating the regulation of these molecules during muscle differentiation in vitro may lead to a better understanding of their role in pathological processes in muscle tissue in vivo...
  9. ncbi Tissue inhibitor of metalloproteinase-2 (TIMP-2) regulates neuromuscular junction development via a beta1 integrin-mediated mechanism
    Gentian Lluri
    Department of Anatomy and Neurobiology, University of Vermont College of Medicine, Burlington, Vermont 05405, USA
    J Neurobiol 66:1365-77. 2006
    ..Given that fast-twitch fibers are lost in muscular dystrophies and age-related sarcopenia, if TIMP-2 regulates mechanotransduction in an MMP-independent manner it opens new potential therapeutic avenues...
  10. ncbi The weight loss elicited by cobalt protoporphyrin is related to decreased activity of nitric oxide synthase in the hypothalamus
    Muyao Li
    Department of Medicine, University of Vermont, C209 Given Bldg, 89 Beaumont Ave, Burlington, Vermont 05405, USA
    J Appl Physiol 100:1983-91. 2006
    ..We also demonstrate that CoPP decreases NOS activity but that it paradoxically increases neuronal NOS transcript expression and increases neuronal NOS protein content on Western blotting...

Research Grants4

  1. Molecular Regulation of TIMP-2 in Neuron Cell Cycle
    DIANE JAWORSKI; Fiscal Year: 2007
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