Christine C Jao

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement
    Christine C Jao
    Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 105:19666-71. 2008
  2. ncbi Computer modeling of nitroxide spin labels on proteins
    Ma mon M Hatmal
    Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA
    Biopolymers 97:35-44. 2012
  3. ncbi Roles of amphipathic helices and the bin/amphiphysin/rvs (BAR) domain of endophilin in membrane curvature generation
    Christine C Jao
    Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033, USA
    J Biol Chem 285:20164-70. 2010
  4. ncbi Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins
    Jobin Varkey
    Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033, USA
    J Biol Chem 285:32486-93. 2010
  5. ncbi Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling
    Christine C Jao
    Department of Biochemistry and Molecular Biology, School of Pharmacy, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 101:8331-6. 2004
  6. ncbi Calcium- and membrane-induced changes in the structure and dynamics of three helical hairpins in annexin B12
    Jose Mario Isas
    Department of Biochemistry and Molecular Biology, Keck School of Medicine of the University of Southern California, Los Angeles, California 90033, USA
    Biochemistry 44:16435-44. 2005
  7. ncbi A combinatorial NMR and EPR approach for evaluating the structural ensemble of partially folded proteins
    Jampani Nageswara Rao
    Department of Biochemistry and Molecular Biology, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, Los Angeles, California 90033, USA
    J Am Chem Soc 132:8657-68. 2010

Collaborators

  • Naoko Mizuno
  • Harvey T McMahon
  • Tobias S Ulmer
  • Alasdair C Steven
  • Ralf Langen
  • Jose Mario Isas
  • Ma mon M Hatmal
  • Balachandra G Hegde
  • Jampani Nageswara Rao
  • Jobin Varkey
  • Prabhavati B Hegde
  • Yiyu Li
  • Ian S Haworth
  • Martin Borch Jensen
  • John C Voss
  • Vikram Kjøller Bhatia
  • Dimitrios G Stamou
  • Jitka Petrlova
  • Harry T Haigler
  • Yujin E Kim

Detail Information

Publications7

  1. ncbi Structure of membrane-bound alpha-synuclein from site-directed spin labeling and computational refinement
    Christine C Jao
    Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 105:19666-71. 2008
    ..Our structural analysis emphasizes the importance of studying membrane protein structure in a bilayer environment...
  2. ncbi Computer modeling of nitroxide spin labels on proteins
    Ma mon M Hatmal
    Department of Pharmacology and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA
    Biopolymers 97:35-44. 2012
    ..5 Å. The speed and accuracy of PRONOX suggest that the algorithm can be used for fitting to DEER data for determination of protein tertiary structure...
  3. ncbi Roles of amphipathic helices and the bin/amphiphysin/rvs (BAR) domain of endophilin in membrane curvature generation
    Christine C Jao
    Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033, USA
    J Biol Chem 285:20164-70. 2010
    ..In this conformation, the amphipathic helices are positioned to act as molecular wedges that induce membrane curvature along the concave surface of the BAR domain...
  4. ncbi Membrane curvature induction and tubulation are common features of synucleins and apolipoproteins
    Jobin Varkey
    Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, California 90033, USA
    J Biol Chem 285:32486-93. 2010
    ..How cellular safeguarding mechanisms prevent such potentially toxic events and whether they go awry in disease remains to be determined...
  5. ncbi Structure of membrane-bound alpha-synuclein studied by site-directed spin labeling
    Christine C Jao
    Department of Biochemistry and Molecular Biology, School of Pharmacy, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Proc Natl Acad Sci U S A 101:8331-6. 2004
    ..Similar helical structures could also apply to apolipoproteins and other lipid-interacting proteins with related 11-aa repeats...
  6. ncbi Calcium- and membrane-induced changes in the structure and dynamics of three helical hairpins in annexin B12
    Jose Mario Isas
    Department of Biochemistry and Molecular Biology, Keck School of Medicine of the University of Southern California, Los Angeles, California 90033, USA
    Biochemistry 44:16435-44. 2005
    ..Possible biological consequences of annexin-induced restriction of membrane mobility are discussed...
  7. ncbi A combinatorial NMR and EPR approach for evaluating the structural ensemble of partially folded proteins
    Jampani Nageswara Rao
    Department of Biochemistry and Molecular Biology, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, 1501 San Pablo Street, Los Angeles, California 90033, USA
    J Am Chem Soc 132:8657-68. 2010
    ....