David S Janowsky

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi request reprint Olanzapine for self-injurious, aggressive, and disruptive behaviors in intellectually disabled adults: a retrospective, open-label, naturalistic trial
    David S Janowsky
    Department of Psychiatry, CB 7175, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7175, USA
    J Clin Psychiatry 64:1258-65. 2003
  2. ncbi request reprint Diagnosis and treatment of depression in patients with mental retardation
    David S Janowsky
    Department of Psychiatry, CB 7175, Medical Research Building A, University of North Carolina, Chapel Hill, NC 27599, USA
    Curr Psychiatry Rep 7:421-8. 2005
  3. ncbi request reprint Serotonergic antidepressant effects on aggressive, self-injurious and destructive/disruptive behaviours in intellectually disabled adults: a retrospective, open-label, naturalistic trial
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    Int J Neuropsychopharmacol 8:37-48. 2005
  4. ncbi request reprint Relapse of aggressive and disruptive behavior in mentally retarded adults following antipsychotic drug withdrawal predicts psychotropic drug use a decade later
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    J Clin Psychiatry 67:1272-7. 2006
  5. ncbi request reprint Anticholinesterase (DFP) toxicity antagonism by chronic donepezil: a potential nerve agent treatment
    David S Janowsky
    Department of Psychiatry, CB 7175, Medical Research Building A, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    Pharmacol Biochem Behav 81:917-22. 2005
  6. doi request reprint Antipsychotic withdrawal-induced relapse predicts future relapses in institutionalized adults with severe intellectual disability
    David S Janowsky
    Department of Psychiatry, CB 7175, Medical Research Building A, University of North Carolina, Chapel Hill, NC 27599 7175, USA
    J Clin Psychopharmacol 28:401-5. 2008
  7. doi request reprint Lithium-induced renal insufficiency: a longitudinal study of creatinine increases in intellectually disabled adults
    David S Janowsky
    Department of Psychiatry, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    J Clin Psychopharmacol 31:769-73. 2011
  8. ncbi request reprint Minimally effective doses of conventional antipsychotic medications used to treat aggression, self-injurious and destructive behaviors in mentally retarded adults
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    J Clin Psychopharmacol 25:19-25. 2005
  9. ncbi request reprint Relationship of Myers Briggs type indicator personality characteristics to suicidality in affective disorder patients
    David S Janowsky
    Department of Psychiatry, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC 27599 7175, USA
    J Psychiatr Res 36:33-9. 2002
  10. ncbi request reprint Historical studies of premenstrual tension up to 30 years ago: implications for future research
    David S Janowsky
    Department of Psychiatry, University of North Carolina, CB 7175, Chapel Hill, NC 27599, USA
    Curr Psychiatry Rep 4:411-8. 2002

Detail Information

Publications23

  1. ncbi request reprint Olanzapine for self-injurious, aggressive, and disruptive behaviors in intellectually disabled adults: a retrospective, open-label, naturalistic trial
    David S Janowsky
    Department of Psychiatry, CB 7175, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599 7175, USA
    J Clin Psychiatry 64:1258-65. 2003
    ..The effectiveness of olanzapine in treating challenging behaviors in the intellectually disabled and its ability to substitute for conventional antipsychotic drugs were evaluated...
  2. ncbi request reprint Diagnosis and treatment of depression in patients with mental retardation
    David S Janowsky
    Department of Psychiatry, CB 7175, Medical Research Building A, University of North Carolina, Chapel Hill, NC 27599, USA
    Curr Psychiatry Rep 7:421-8. 2005
    ..This article reviews numerous studies elaborating on the diagnosis, phenomenology, and treatment of depression in mentally retarded individuals...
  3. ncbi request reprint Serotonergic antidepressant effects on aggressive, self-injurious and destructive/disruptive behaviours in intellectually disabled adults: a retrospective, open-label, naturalistic trial
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    Int J Neuropsychopharmacol 8:37-48. 2005
    ..The results suggest that serotonergic antidepressants are useful in the treatment of challenging/maladaptive behaviours in the intellectually disabled...
  4. ncbi request reprint Relapse of aggressive and disruptive behavior in mentally retarded adults following antipsychotic drug withdrawal predicts psychotropic drug use a decade later
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    J Clin Psychiatry 67:1272-7. 2006
    ..The purpose of this study was to determine if relapse during or after antipsychotic drug withdrawal in mentally retarded adults predicts continuing antipsychotic drug use an average of a decade later...
  5. ncbi request reprint Anticholinesterase (DFP) toxicity antagonism by chronic donepezil: a potential nerve agent treatment
    David S Janowsky
    Department of Psychiatry, CB 7175, Medical Research Building A, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    Pharmacol Biochem Behav 81:917-22. 2005
    ..Although these phenomena are not the same as lethality, they may be parallel phenomena, and our results may have therapeutic implications for the treatment of nerve agent toxicity...
  6. doi request reprint Antipsychotic withdrawal-induced relapse predicts future relapses in institutionalized adults with severe intellectual disability
    David S Janowsky
    Department of Psychiatry, CB 7175, Medical Research Building A, University of North Carolina, Chapel Hill, NC 27599 7175, USA
    J Clin Psychopharmacol 28:401-5. 2008
    ..Thus, if relapse occurs after an antipsychotic drug withdrawal attempt, subsequent attempts at withdrawal are also very likely to lead to further relapses...
  7. doi request reprint Lithium-induced renal insufficiency: a longitudinal study of creatinine increases in intellectually disabled adults
    David S Janowsky
    Department of Psychiatry, University of North Carolina Chapel Hill, Chapel Hill, NC, USA
    J Clin Psychopharmacol 31:769-73. 2011
    ..Lithium has been shown to increase serum creatinine levels in a subgroup of patients. However, lithium-induced increases in serum creatinine have not been well studied with regard to timing, trajectory, or predictability...
  8. ncbi request reprint Minimally effective doses of conventional antipsychotic medications used to treat aggression, self-injurious and destructive behaviors in mentally retarded adults
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    J Clin Psychopharmacol 25:19-25. 2005
    ..3 mg/d and relapse occurred at a mean dose of 93.6 mg/d. The mean lowest effective dose of haloperidol or related high potency drugs (expressed as haloperidol equivalents) was 5.9 mg/d, and relapse occurred at a mean dose of 3.8 mg/d...
  9. ncbi request reprint Relationship of Myers Briggs type indicator personality characteristics to suicidality in affective disorder patients
    David S Janowsky
    Department of Psychiatry, University of North Carolina at Chapel Hill, School of Medicine, Chapel Hill, NC 27599 7175, USA
    J Psychiatr Res 36:33-9. 2002
    ....
  10. ncbi request reprint Historical studies of premenstrual tension up to 30 years ago: implications for future research
    David S Janowsky
    Department of Psychiatry, University of North Carolina, CB 7175, Chapel Hill, NC 27599, USA
    Curr Psychiatry Rep 4:411-8. 2002
    ..Current applications and potential research directions based on this information are also discussed...
  11. ncbi request reprint Myers Briggs Type indicator personality profiles in unipolar depressed patients
    David S Janowsky
    School of Medicine and Department of Psychiatry, University of North Carolina at Chapel Hill, North Carolina, USA
    World J Biol Psychiatry 3:207-15. 2002
    ..The current study was designed to compare the distribution of Myers Briggs Type Indicator (MBTI) personality types in patients with Unipolar Depression compared to normative data...
  12. ncbi request reprint Preference for higher sucrose concentrations in cocaine abusing-dependent patients
    David S Janowsky
    Department of Psychiatry, CB 7175, Medical Research Building A, University of North Carolina at Chapel Hill, NC 27599 7175, USA
    J Psychiatr Res 37:35-41. 2003
    ..There also is evidence in humans that alcoholics prefer high concentration sweet solutions. This study was designed to determine whether patients with cocaine use disorder also prefer high concentrations of sweet solutions...
  13. ncbi request reprint Bipolar disorder- and major depression-relevant abstracts from the 2009 9th World Congress of Biological Psychiatry Meeting
    David S Janowsky
    Department of Psychiatry, University of North Carolina Chapel Hill School of Medicine, 110 Connor Drive, Chapel Hill, NC 27514, USA
    Curr Psychiatry Rep 11:509-11. 2009
    ....
  14. doi request reprint Lithium effect on renal glomerular function in individuals with intellectual disability
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7160, USA
    J Clin Psychopharmacol 29:296-9. 2009
    ..The current study evaluated the effects of chronic administration of lithium on renal functioning in an intellectually disabled population...
  15. ncbi request reprint Current issues in the treatment of depression in bipolar disorder patients
    David S Janowsky
    Department of Psychiatry, CB 7175, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Curr Psychiatry Rep 7:485-6. 2005
    ..The major focus of this review is on the nature and treatment of depression in bipolar disorder patients, and includes information generally not previously circulated to psychiatric professionals...
  16. ncbi request reprint Bipolar disorder-relevant abstracts of posters from the 2008 CINP congress
    David S Janowsky
    Department of Psychiatry, CB 7160, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7160, USA
    Curr Psychiatry Rep 10:525-7. 2008
    ....
  17. ncbi request reprint Recent depression updates: relevant presentations
    David S Janowsky
    Department of Psychiatry, CB 7175, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7175, USA
    Curr Psychiatry Rep 8:470-2. 2006
    ..Described are several novel psychopharmacologic treatments for major depressive disorder, some predictors of efficacy, and information relevant to understanding the activation of the hypothalamic-pituitary-adrenal axis in depression...
  18. ncbi request reprint Issues of functionality in bipolar disorders
    David S Janowsky
    Department of Psychiatry, CB 7175, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Curr Psychiatry Rep 6:449-50. 2004
    ..In contrast, the current summary of studies focuses on the impact of bipolar disorders on functionality as this relates to such variables as self-satisfaction, the ability to work, and the ability to get along interpersonally...
  19. ncbi request reprint Effects of topiramate on aggressive, self-injurious, and disruptive/destructive behaviors in the intellectually disabled: an open-label retrospective study
    David S Janowsky
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, USA
    J Clin Psychopharmacol 23:500-4. 2003
    ..The results suggest that topiramate may have a role in the treatment of challenging/maladaptive behaviors in intellectually disabled individuals...
  20. ncbi request reprint Depression and dysphoria effects on the interpersonal perception of negative and positive moods and caring relationships: effects of antidepressants, amphetamine, and methylphenidate
    David S Janowsky
    Department of Psychiatry, CB 7175, University of North Carolina, Chapel Hill, NC 27599, USA
    Curr Psychiatry Rep 5:451-9. 2003
    ..The theoretic and therapeutic implications of these relationships are discussed herewith...
  21. ncbi request reprint Antagonism of anticholinesterase (DFP) toxicity by donepezil plus scopolamine: a preliminary study
    David S Janowsky
    Department of Psychiatry, University of North Carolina, CB 7175, Medical Research Building A, Chapel Hill, NC 27599 7175, USA
    Pharmacol Biochem Behav 77:337-43. 2004
    ..Therefore, these preliminary findings are encouraging, but many additional studies are needed to establish the effectiveness of donepezil as a prophylactic agent against irreversible cholinesterase inhibition by DFP...
  22. ncbi request reprint Central anticholinergics to treat nerve-agent poisoning
    David S Janowsky
    Lancet 359:265-6. 2002
  23. ncbi request reprint Comment on "preclinical models: status of basic research in depression"
    David H Overstreet
    Biol Psychiatry 53:268-70; author reply 270. 2003