Research Topics
| MICHELLE C JANELSINSSummaryAffiliation: University of Rochester Country: USA Publications
Research Grants
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Detail Information
Publications
Differential expression of cytokines in breast cancer patients receiving different chemotherapies: implications for cognitive impairment researchMICHELLE C JANELSINS
Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY 14642, USA
Support Care Cancer 20:831-9. 2012....
Effects of Tai Chi Chuan on insulin and cytokine levels in a randomized controlled pilot study on breast cancer survivorsMICHELLE C JANELSINS
Department of Radiation Oncology, University of Rochester Medical Center, New York, NY 14642, USA
Clin Breast Cancer 11:161-70. 2011..Despite knowing the beneficial effects of conventional exercise interventions on these mediators, little is known about the physiologic effects of TCC on these pathways in breast cancer survivors...
An update on cancer- and chemotherapy-related cognitive dysfunction: current statusMICHELLE C JANELSINS
Department of Radiation Oncology, University of Rochester Medical Center, Rochester, NY 14642, USA
Semin Oncol 38:431-8. 2011..Mostly we focus is on cognitive effects of adjuvant chemotherapy for breast cancer; however, cognitive effects of chemotherapy on the elderly and brain tumor patients are also discussed...
IGF-1 partially restores chemotherapy-induced reductions in neural cell proliferation in adult C57BL/6 miceMICHELLE C JANELSINS
Department of Radiation Oncology, University of Rochester Medical Center, New York 14642, USA
Cancer Invest 28:544-53. 2010..Insulin-like growth factor 1, a molecule implicated in promoting neurogenesis, counteracted the effects of high doses of chemotherapy on neural cell proliferation...
Health-related quality of life and biomarkers in breast cancer survivors participating in tai chi chuanLisa K Sprod
James P Wilmot Cancer Center, University of Rochester, Rochester, NY 14642, USA
J Cancer Surviv 6:146-54. 2012..Breast cancer survivors experience diminished health-related quality of life (HRQOL). We report on the influence of tai chi chuan exercise (TCC) on HRQOL and explore associations between changes in HRQOL and biomarkers...
Effects of a structured weight-bearing exercise program on bone metabolism among breast cancer survivors: a feasibility trialLuke J Peppone
Department of Radiation Oncology, University of Rochester Medical Center, NY 14642, USA
Clin Breast Cancer 10:224-9. 2010..This pilot study compared the influence of TCC with that of standard support therapy (ST; exercise control) on BL biomarkers among breast cancer survivors...
The effect of cigarette smoking on cancer treatment-related side effectsLuke J Peppone
Department of Radiation Oncology, University of Rochester, Rochester, New York 14642, USA
Oncologist 16:1784-92. 2011..This study examines the influence of cigarette smoking on side effects among 947 cancer patients during and 6 months following treatment...
Exercise for the management of side effects and quality of life among cancer survivorsKaren M Mustian
University of Rochester School of Medicine and Dentistry, James P Wilmot Cancer Center, Department of Radiation Oncology, Rochester, NY, USA
Curr Sports Med Rep 8:325-30. 2009....
The effect of various vitamin D supplementation regimens in breast cancer patientsLuke J Peppone
Department of Radiation Oncology, University of Rochester Medical Center, 601 Elmwood Ave, Box 704, Rochester, NY 14642, USA
Breast Cancer Res Treat 127:171-7. 2011..Clinicians should carefully consider vitamin D supplementation regimens when treating vitamin D deficiency/insufficiency in breast cancer patients...
Prevalence, demographics, and psychological associations of sleep disruption in patients with cancer: University of Rochester Cancer Center-Community Clinical Oncology ProgramOxana G Palesh
Department of Radiation Oncology, Department of Psychiatry, University of Rochester Medical Center, James P Wilmot Cancer Center, 601 Elmwood Ave, Box 704, Rochester, New York, NY 14642, USA
J Clin Oncol 28:292-8. 2010..Sleep disruption is prevalent in patients with cancer and survivors, but the prevalence of insomnia, a distressing sleep disorder, in these populations has yet to be determined in large-scale studies...
The association between breast cancer prognostic indicators and serum 25-OH vitamin D levelsLuke J Peppone
Department of Radiation Oncology, University of Rochester Medical Center, Rochester, New York, NY, USA
Ann Surg Oncol 19:2590-9. 2012..The aim of this study is to examine 25-OH vitamin D levels between BC cases and controls and by prognostic indicators among BC cases...
Prevention of pegfilgrastim-induced bone pain: a phase III double-blind placebo-controlled randomized clinical trial of the university of rochester cancer center clinical community oncology program research baseJeffrey J Kirshner
Hematology Oncology Associates of Central New York, Community Clinical Oncology Program, East Syracuse, NY, USA
J Clin Oncol 30:1974-9. 2012..Pegfilgrastim-induced bone pain is a significant clinical problem that may result in discontinuation of pegfilgrastim and lead to less effective chemotherapy dosing. Interventions for pegfilgrastim-induced bone pain are needed...
Current pharmacotherapy for chemotherapy-induced nausea and vomiting in cancer patientsMICHELLE C JANELSINS
University of Rochester Medical Center, James P Wilmot Cancer Center, Department of Radiation Oncology, 265 Crittenden Blvd, Box 658, Rochester, NY 14642, USA
Expert Opin Pharmacother 14:757-66. 2013..It is critical to focus attention on better understanding the mechanisms underlying nausea, anticipatory symptoms and delayed symptoms...
Triple-transgenic Alzheimer's disease mice exhibit region-specific abnormalities in brain myelination patterns prior to appearance of amyloid and tau pathologyMaya K Desai
Department of Pharmacology and Physiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
Glia 57:54-65. 2009....
Chronic neuron-specific tumor necrosis factor-alpha expression enhances the local inflammatory environment ultimately leading to neuronal death in 3xTg-AD miceMICHELLE C JANELSINS
Department of Microbiology and Immunology, Center for Neural Development and Disease, University of Rochester Medical Center, Rochester, NY 14642, USA
Am J Pathol 173:1768-82. 2008..Results presented here suggest that chronic neuronal TNF-alpha expression promotes inflammation and, ultimately, neuronal cell death in this AD mouse model, advocating the development of TNF-alpha-specific agents to subvert AD...
Research Grants
- Modulating Disease in Alzheimer's Disease ModelsMICHELLE JANELSINS; Fiscal Year: 2007..This work will give us major insight on the involvement of inflammation in the temporal and spatial progression of early AD pathogenic events and may potentially provide a new therapeutic target. ..
