John A Jane

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. doi request reprint Impact of the Accreditation Council for Graduate Medical Education work-hour regulations on neurosurgical resident education and productivity
    Jay Jagannathan
    Departments of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    J Neurosurg 110:820-7. 2009
  2. doi request reprint Early outcomes of endoscopic transsphenoidal surgery for adult craniopharyngiomas
    John A Jane
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia, USA
    Neurosurg Focus 28:E9. 2010
  3. doi request reprint The transsphenoidal resection of pediatric craniopharyngiomas: a case series
    John A Jane
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg Pediatr 5:49-60. 2010
  4. doi request reprint Endoscopic vs microsurgical transsphenoidal surgery for acromegaly: outcomes in a concurrent series of patients using modern criteria for remission
    Robert M Starke
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Clin Endocrinol Metab 98:3190-8. 2013
  5. doi request reprint Use of the histological pseudocapsule in surgery for Cushing disease: rapid postoperative cortisol decline predicting complete tumor resection
    Stephen J Monteith
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, USA
    J Neurosurg 116:721-7. 2012
  6. doi request reprint Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications, and predictors of outcome
    John A Jane
    Departments of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908 0711, USA
    J Clin Endocrinol Metab 96:2732-40. 2011
  7. ncbi request reprint History of endoscopic skull base surgery: its evolution and current reality
    Daniel M Prevedello
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    J Neurosurg 107:206-13. 2007
  8. doi request reprint The posterior cervical foraminotomy in the treatment of cervical disc/osteophyte disease: a single-surgeon experience with a minimum of 5 years' clinical and radiographic follow-up
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22902, USA
    J Neurosurg Spine 10:347-56. 2009
  9. ncbi request reprint Benign brain tumors: sellar/parasellar tumors
    Jay Jagannathan
    Department of Neurosurgery, University of Virginia Health System, PO Box 800212, Charlottesville, VA 22908 0711, USA
    Neurol Clin 25:1231-49, xi. 2007
  10. doi request reprint Pituitary tumors
    Gautam U Mehta
    Department of Neurosurgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22908 0711, USA
    Curr Opin Neurol 25:751-5. 2012

Detail Information

Publications44

  1. doi request reprint Impact of the Accreditation Council for Graduate Medical Education work-hour regulations on neurosurgical resident education and productivity
    Jay Jagannathan
    Departments of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    J Neurosurg 110:820-7. 2009
    ..The authors have evaluated multiple objective surrogate markers of resident performance and quality of training to determine the impact of the 80-hour workweek...
  2. doi request reprint Early outcomes of endoscopic transsphenoidal surgery for adult craniopharyngiomas
    John A Jane
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia, USA
    Neurosurg Focus 28:E9. 2010
    ..The purpose of this study was to report the outcomes of the endoscopic transsphenoidal approach for adults with craniopharyngiomas in whom the goal was gross-total resection...
  3. doi request reprint The transsphenoidal resection of pediatric craniopharyngiomas: a case series
    John A Jane
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg Pediatr 5:49-60. 2010
    ..The purpose of this study is to report the outcomes after transsphenoidal surgery in a consecutive series of pediatric patients with craniopharyngiomas treated at a single institution with the goal of gross-total resection (GTR)...
  4. doi request reprint Endoscopic vs microsurgical transsphenoidal surgery for acromegaly: outcomes in a concurrent series of patients using modern criteria for remission
    Robert M Starke
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Clin Endocrinol Metab 98:3190-8. 2013
    ..It is unclear whether endoscopic transsphenoidal surgery (ETSS) or microsurgical transsphenoidal surgery (MTS) is a superior surgical approach for pituitary adenomas...
  5. doi request reprint Use of the histological pseudocapsule in surgery for Cushing disease: rapid postoperative cortisol decline predicting complete tumor resection
    Stephen J Monteith
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, VA, USA
    J Neurosurg 116:721-7. 2012
    ..Furthermore, the relevance of the rate of cortisol drop immediately after surgery has not been investigated...
  6. doi request reprint Endoscopic transsphenoidal surgery for acromegaly: remission using modern criteria, complications, and predictors of outcome
    John A Jane
    Departments of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908 0711, USA
    J Clin Endocrinol Metab 96:2732-40. 2011
    ..Despite the growing application of endoscopic transsphenoidal surgery (ETSS), outcomes for GH adenomas are not clearly defined...
  7. ncbi request reprint History of endoscopic skull base surgery: its evolution and current reality
    Daniel M Prevedello
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    J Neurosurg 107:206-13. 2007
    ..This article discusses the history of the endoscope, the pivotal technological advances, and the key figures in the burgeoning field of endoneurosurgery...
  8. doi request reprint The posterior cervical foraminotomy in the treatment of cervical disc/osteophyte disease: a single-surgeon experience with a minimum of 5 years' clinical and radiographic follow-up
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22902, USA
    J Neurosurg Spine 10:347-56. 2009
    ..This study details long-term clinical and radiographic outcomes following single-level posterior cervical foraminotomy for degenerative disc or osteophyte disease...
  9. ncbi request reprint Benign brain tumors: sellar/parasellar tumors
    Jay Jagannathan
    Department of Neurosurgery, University of Virginia Health System, PO Box 800212, Charlottesville, VA 22908 0711, USA
    Neurol Clin 25:1231-49, xi. 2007
    ..Less invasive modalities, such as endoscopic transsphenoidal surgery, specific chemotherapeutic drugs, and stereotactic radiosurgery, show promise as adjuvant treatment modalities...
  10. doi request reprint Pituitary tumors
    Gautam U Mehta
    Department of Neurosurgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22908 0711, USA
    Curr Opin Neurol 25:751-5. 2012
    ..The aim of this article is to review current research in the treatment of pituitary tumors and summarize emerging medical, surgical and radiation-based therapies...
  11. doi request reprint Radiographic and clinical outcomes following single-level anterior cervical discectomy and allograft fusion without plate placement or cervical collar
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Box 800212, Charlottesville, Virginia 22908, USA
    J Neurosurg Spine 8:420-8. 2008
    ..This paper examines a single-surgeon experience with single-level ACDF without use of plates or hard collars in patients with degenerative spondylosis in whom allograft was used as the fusion material...
  12. ncbi request reprint Computer-assisted frameless stereotaxy in transsphenoidal surgery at a single institution: review of 176 cases
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 00212, USA
    Neurosurg Focus 20:E9. 2006
    ..In this study the authors address the efficacy and safety of frameless stereotaxy in transsphenoidal surgery...
  13. doi request reprint Endoscopic transsphenoidal surgery for cushing disease: techniques, outcomes, and predictors of remission
    Robert M Starke
    Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    Neurosurgery 72:240-7; discussion 247. 2013
    ..The efficacy of endoscopic transsphenoidal surgery (ETS) for Cushing disease has not been clearly established...
  14. doi request reprint Gamma Knife surgery for patients with nonfunctioning pituitary macroadenomas: predictors of tumor control, neurological deficits, and hypopituitarism
    Robert M Starke
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    J Neurosurg 117:129-35. 2012
    ..In this study, the authors evaluated outcomes following GKS of nonfunctioning pituitary macroadenomas and assessed predictors of tumor control, neurological deficits, and delayed hypopituitarism...
  15. ncbi request reprint Brief history of endoscopic transsphenoidal surgery--from Philipp Bozzini to the First World Congress of Endoscopic Skull Base Surgery
    Francesco Doglietto
    Department of Neurological Surgery, University of Virginia Health Systems, Charlottesville, Virginia, USA
    Neurosurg Focus 19:E3. 2005
    ..Specifically, in this review the history of endoscopy and its application in endonasal neurosurgery are presented...
  16. ncbi request reprint Outcome following decompressive craniectomy in children with severe traumatic brain injury: a 10-year single-center experience with long-term follow up
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 106:268-75. 2007
    ..The authors examine the indications for and outcomes following decompressive craniectomy in a single-center pediatric patient population with traumatic brain injury (TBI)...
  17. doi request reprint Electrophysiologically guided untethering of secondary tethered spinal cord syndrome
    Nader Pouratian
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia, USA
    Neurosurg Focus 29:E3. 2010
    ..In addition, the authors describe the use of electrophysiological guidance to identify an "autonomous placode" in the untethering of the cord in STCS...
  18. doi request reprint Long-term outcomes and prognostic factors in pediatric patients with severe traumatic brain injury and elevated intracranial pressure
    Jay Jagannathan
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg Pediatr 2:240-9. 2008
    ..The management strategies and outcomes in pediatric patients with elevated intracranial pressure (ICP) following severe traumatic brain injury (TBI) are examined in this study...
  19. ncbi request reprint Reconstruction of the sellar dura in transsphenoidal surgery using an expanded polytetrafluoroethylene dural substitute
    Jonathan H Sherman
    Department of Neurological Surgery, University of Virginia, Health Sciences Center, Charlottesville, Box 800212, VA 22908, USA
    Surg Neurol 69:73-6; discussion 76. 2008
    ..We studied the use of an ePTFE dural substitute (GORE Preclude MVP, W.L. Gore & Associates, Flagstaff, Arizona, USA), as a method for obtaining reliable reconstruction of the sellar dura...
  20. ncbi request reprint Perspectives on endoscopic transsphenoidal surgery
    John A Jane
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 19:E2. 2005
    ..The authors describe their current endoscopic technique and elucidate the advantages and disadvantages of the pure endoscopic adenomectomy compared with the standard microscopic approach...
  21. doi request reprint Temozolomide treatment for aggressive pituitary tumors: correlation of clinical outcome with O(6)-methylguanine methyltransferase (MGMT) promoter methylation and expression
    Zachary M Bush
    Division of Endocrinology and Metabolism, University of Virginia, Charlottesville, Virginia 22908 0214, USA
    J Clin Endocrinol Metab 95:E280-90. 2010
    ..Recently, case reports have described efficacy of temozolomide for the treatment of aggressive pituitary tumors...
  22. ncbi request reprint Extended transsphenoidal approach
    Aaron S Dumont
    Department of Neurological Surgery, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
    Front Horm Res 34:29-45. 2006
    ..Meticulous attention to detail, particularly with respect to reconstruction and closure of the sellar floor, is necessary for its effective application...
  23. ncbi request reprint Genetics of pituitary adenomas: current theories and future implications
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
    Neurosurg Focus 19:E4. 2005
    ..These tumors can still be extremely difficult to manage, however, and can cause significant morbidity to the patient, both from tumor mass effect and secondary to hormonal imbalances...
  24. ncbi request reprint Diagnosis and management of pediatric sellar lesions
    Jay Jagannathan
    Department of Neurological Surgery, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
    Front Horm Res 34:83-104. 2006
    ..Less invasive modalities such as endoscopic transsphenoidal surgery, and stereotactic radiosurgery have shown promise as primary and adjuvant treatment modalities, respectively...
  25. doi request reprint Immunohistochemistry of COUP-TFI: an adjuvant diagnostic tool for the identification of corticotroph microadenomas
    Zachary M Bush
    Division of Endocrinology and Metabolism, University of Virginia Health System, P O Box 801408, Charlottesville, VA, 22908 1408, USA
    Pituitary 13:1-7. 2010
    ..Furthermore, this study identifies two unique corticotroph tumor populations which differ in their expression of COUP-TFI, the presence of which occurs more frequently in macroadenomas...
  26. ncbi request reprint Hypophysitis
    Edward R Laws
    School of Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Pituitary 9:331-3. 2006
    ..Therapy is generally supportive in nature but may require surgery for pathological diagnosis and treatment of mass effect...
  27. ncbi request reprint Management of pediatric sellar tumors
    John A Jane
    Department of Neurosurgery, School of Medicine, University of Virginia, Charlottesville, VA 22903, USA
    Pediatr Endocrinol Rev 5:720-6. 2008
    ..Other less invasive treatments include intracavitary therapy and debulking followed by radiation therapy or stereotactic radiosurgery. Overall, the management of these tumors requires a multidisciplinary approach...
  28. doi request reprint A lesson in history: the evolution of endoscopic third ventriculostomy
    Paul J Schmitt
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 33:E11. 2012
    ..Neurosurgeons would be wise to take the lessons learned in modernizing the ETV procedure and reassure themselves that these lessons do not apply to other methods that are tempting to dismiss as antiquated or archaic...
  29. ncbi request reprint Cervical spine injuries in pediatric athletes: mechanisms and management
    Jay Jagannathan
    Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908 00212, USA
    Neurosurg Focus 21:E6. 2006
    ..The aim of this review was to detail the characteristics and management of pediatric cervical spine injury...
  30. doi request reprint Outcomes of bone morphogenetic protein-2 in mature adults: posterolateral non-instrument-assisted lumbar decompression and fusion
    D Kojo Hamilton
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, VA 22908, USA
    Surg Neurol 69:457-61; discussion 461-2. 2008
    ..This retrospective analysis presents a comprehensive examination of spinal fusion, functional outcomes, and pain relief in a growing elderly population in which a BMP was used...
  31. ncbi request reprint Rathke's cleft cysts
    Adam S Kanter
    Department of Neurological Surgery, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
    Front Horm Res 34:127-57. 2006
    ..This chapter aims to review the pathogenesis, symptomatologic manifestations, radiographic, morphologic and histopathological characteristics, treatment strategies and outcomes in the cysts of Rathke's cleft...
  32. ncbi request reprint Chiari malformations in patients with uncorrected sagittal synostosis
    Nader Pouratian
    Division of Pediatric Neurosurgery, Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908 0212, USA
    Surg Neurol 67:422-7; discussion 427-8. 2007
    ..Single suture craniosynostoses were long considered a benign condition with little risk of complications. In many cases, parents may forego surgical correction because of the inherent risks of surgical intervention...
  33. pmc A novel fixative for immunofluorescence staining of CD133-positive glioblastoma stem cells
    Jonathan H Sherman
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA
    J Neurosci Methods 198:99-102. 2011
    ..Here we present the use of a novel fixative (1,4-benzoquinone) for immunoflourescence staining of neurospheres...
  34. ncbi request reprint Evaluation and management of Cushing syndrome in cases of negative sellar magnetic resonance imaging
    Jay Jagannathan
    Department of Neurosurgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 23:E3. 2007
    ..Radiosurgery is an effective treatment option in patients with persistent Cushing disease. When a target cannot be found on MR imaging, one can target the entire sellar region with radiosurgery...
  35. ncbi request reprint Relevance of high Ki-67 in pituitary adenomas. Case report and review of the literature
    Daniel M Prevedello
    Department of Neurological Surgery and Neuropathology, University of Virginia Health System, Charlottesville, Virginia 22908 00212, USA
    Neurosurg Focus 19:E11. 2005
    ..The relationships between high Ki-67 LIs and tumor recurrence, invasiveness, and growth velocity in pituitary adenomas are reviewed...
  36. ncbi request reprint Contrast ultrasonographic assessment of cerebral perfusion in patients undergoing decompressive craniectomy for traumatic brain injury
    Peter Heppner
    Cardiovascular Division, and Departments of Neurological Surgery and Anesthesiology, University of Virginia Health System, Charlottesville, Virginia, USA
    J Neurosurg 104:738-45. 2006
    ....
  37. ncbi request reprint Image guidance in pituitary surgery
    Ashok R Asthagiri
    Department of Neurological Surgery, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
    Front Horm Res 34:46-63. 2006
    ..The utility and limitations of common intraoperative aides including video fluoroscopy, frameless stereotaxy, ultrasound, and magnetic resonance imaging are reviewed...
  38. doi request reprint Conservative management of an acute spontaneous holocord epidural hemorrhage in a hemophiliac infant
    Erin N Kiehna
    Department of Neurosurgery, University of VirginiaHealth System, Charlottesville, Virginia 22908, USA
    J Neurosurg Pediatr 6:43-8. 2010
    ..Observation with aggressive correction of coagulopathy is a reasonable treatment choice for hemophilic patients presenting with SEH and a stable neurological examination...
  39. ncbi request reprint Capillary hemangioma of the cauda equina presenting with radiculopathy and papilledema
    Nicola G Ghazi
    Department of Ophthalmology, University of Virginia Health System, PO Box 800715, Charlottesville, Virginia 22908, USA
    J Neuroophthalmol 26:98-102. 2006
    ..If papilledema is present, spinal cord imaging should be performed when lumbar puncture discloses unexplained protein elevation and in cases that lack clinical features typical of idiopathic intracranial hypertension...
  40. doi request reprint Lennart Heimer: concepts of the ventral striatum and extended amygdala
    W Jeff Elias
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    Neurosurg Focus 25:E8. 2008
    ..His legendary sessions with neurosurgical residents resulted in his recognition as one of the world's leading fiber tract dissectors. His gentle, engaging manner has been documented in several media formats...
  41. doi request reprint Intramedullary spinal cord metastasis from bladder carcinoma: case report
    R Webster Crowley
    Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia 22908, USA
    Neurosurgery 63:E611-2; discussion E612. 2008
    ..The authors report the second known case of an intramedullary spinal cord metastatic lesion arising from primary bladder carcinoma...
  42. doi request reprint Brain abscess in children
    Jason P Sheehan
    Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia, USA
    Neurosurg Focus 24:E6. 2008
    ..Although the effectiveness of medical management has improved and some children may be treated with antimicrobial therapy alone, surgical evaluation remains an important component of the treatment algorithm for most pediatric patients...
  43. ncbi request reprint Primary disseminated leptomeningeal oligodendroglioma with 1p deletion. Case report
    T David Bourne
    Department of Pathology, Division of Neuropathology, University of Virginia Health System, Charlottesville, Virginia 22908 0214, USA
    J Neurosurg 105:465-9. 2006
    ..The deletion of lp was demonstrated by FISH analysis; lq, 19p, and 19q were intact. This appears to be the first reported case of a primary diffuse leptomeningeal oligodendroglioma in which a lp deletion was identified...
  44. ncbi request reprint Surgery for primary brain tumors at United States academic training centers: results from the Residency Review Committee for neurological surgery
    John A Jane
    Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
    J Neurosurg 103:789-93. 2005
    ..The scope of such cases and the proportion of surgeries performed transsphenoidally are an interesting means of tracking the effectiveness of residency education...