Research Topics
Species | Diana I JalalSummaryAffiliation: University of Colorado Denver Country: USA Publications
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Detail Information
Publications
Uric acid as a target of therapy in CKDDiana I Jalal
Division of Renal Diseases and Hypertension, University of Colorado School of Medicine, Denver, CO 80045, USA
Am J Kidney Dis 61:134-46. 2013..Although uric acid also may be linked to cardiovascular disease and mortality in patients with CKD, this review focuses only on uric acid as a potential therapeutic target to prevent kidney disease onset and progression...
C-reactive protein as a predictor of cardiovascular events in elderly patients with chronic kidney diseaseDiana Jalal
Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, Colorado 80045, USA
J Nephrol 25:719-25. 2012..Few studies have evaluated the relationship between high-sensitivity C-reactive protein (hs-CRP) and vascular events in the elderly with chronic kidney disease (CKD)...
Vascular endothelial function is not related to serum uric acid in healthy adultsDiana I Jalal
Division of Renal Diseases and Hypertension, University of Colorado Denver, USA
Am J Hypertens 25:407-13. 2012..It is controversial if high uric acid levels and impaired endothelial function are related in healthy adults. In addition, the effect of uric acid on endothelial cells (ECs) of humans is unexplored...
Serum uric acid levels predict the development of albuminuria over 6 years in patients with type 1 diabetes: findings from the Coronary Artery Calcification in Type 1 Diabetes studyDiana I Jalal
Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO, USA
Nephrol Dial Transplant 25:1865-9. 2010..Recent studies suggest that uric acid is a mediator of diabetic nephropathy. We hypothesized that elevated serum uric acid levels are a strong predictor of albuminuria in patients with type 1 diabetes...
Uric acid as a mediator of diabetic nephropathyDiana I Jalal
Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO 80045, USA
Semin Nephrol 31:459-65. 2011..Based on the evidence we review, we conclude the need for properly planned randomized controlled studies to decrease uric acid levels and assess the impact of such therapy on diabetic kidney disease...
Increased fructose associates with elevated blood pressureDiana I Jalal
Division of Renal Diseases and Hypertension, University of Colorado Denver Health Sciences Center, 12700 E 19th Avenue, Research 2, C281, Aurora, CO 80045, USA
J Am Soc Nephrol 21:1543-9. 2010..These results suggest that high fructose intake, in the form of added sugar, independently associates with higher BP levels among US adults without a history of hypertension...
Serum uric acid predicts progression of subclinical coronary atherosclerosis in individuals without renal diseaseTiciana C Rodrigues
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado, USA
Diabetes Care 33:2471-3. 2010..To examine uric acid (UA) as a possible predictor of the progression of coronary artery calcification (CAC) using data from the prospective Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study...
Elevated serum uric acid levels are associated with non-alcoholic fatty liver disease independently of metabolic syndrome features in the United States: Liver ultrasound data from the National Health and Nutrition Examination SurveyJeffrey C Sirota
Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO, USA
Metabolism 62:392-9. 2013..Experimental and observational studies suggest a role for uric acid in non-alcoholic fatty liver disease (NAFLD). We examined the association between serum uric acid levels and NAFLD in a large population-based study from the United States...
Association between nonalcoholic liver disease and chronic kidney disease: an ultrasound analysis from NHANES 1988-1994Jeffrey C Sirota
University of Colorado at Denver Health Sciences Center, Aurora, USA
Am J Nephrol 36:466-71. 2012..We hypothesized that NAFLD is associated with CKD and that greater severity of NAFLD is associated with higher odds of CKD...
Disorders of hemostasis associated with chronic kidney diseaseDiana I Jalal
Division of Renal Diseases and Hypertension, University of Colorado Denver, Aurora, CO, USA
Semin Thromb Hemost 36:34-40. 2010..This review critically appraises studies examining the abnormalities in the hemostasis pathway in patients with CKD, as well as the therapeutic options that are currently available to treat these individuals...
