Anil K Jain

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc 2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin
    Anil K Jain
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Denver, 12700 East 19th Avenue, Box C238 P 15 Research 2, Aurora, CO 80045, USA
    Toxicology 282:129-38. 2011
  2. pmc Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin
    Anil K Jain
    Department of Pharmaceutical Sciences, University of Colorado Denver School of Pharmacy, Aurora, CO 80045, USA
    Toxicol Lett 205:293-301. 2011
  3. pmc Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation
    Neera Tewari-Singh
    Department of Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado, United States of America
    PLoS ONE 7:e46149. 2012
  4. pmc Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells
    Manjinder Kaur
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Cancer Center, University of Colorado, Aurora, CO 80045, USA
    Carcinogenesis 34:1585-92. 2013
  5. doi request reprint Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries
    Neera Tewari-Singh
    Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO 80045, USA
    Toxicol Appl Pharmacol 264:23-31. 2012
  6. doi request reprint Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin
    Swetha Inturi
    Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, 12850 E Montview Blvd, Aurora, CO 80045, USA Electronic address
    Toxicology 311:184-90. 2013
  7. pmc Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation
    Molly M Derry
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
    Cancer Prev Res (Phila) 6:625-33. 2013
  8. pmc Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice
    Neera Tewari-Singh
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado, United States of America
    PLoS ONE 8:e67557. 2013
  9. pmc Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells
    Samiha Mateen
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA
    Epigenetics 7:1161-72. 2012
  10. pmc Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells
    Sangeeta Shrotriya
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA
    Carcinogenesis 33:848-58. 2012

Collaborators

Detail Information

Publications11

  1. pmc 2-Chloroethyl ethyl sulfide causes microvesication and inflammation-related histopathological changes in male hairless mouse skin
    Anil K Jain
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Colorado Denver, 12700 East 19th Avenue, Box C238 P 15 Research 2, Aurora, CO 80045, USA
    Toxicology 282:129-38. 2011
    ....
  2. pmc Sulfur mustard analog, 2-chloroethyl ethyl sulfide-induced skin injury involves DNA damage and induction of inflammatory mediators, in part via oxidative stress, in SKH-1 hairless mouse skin
    Anil K Jain
    Department of Pharmaceutical Sciences, University of Colorado Denver School of Pharmacy, Aurora, CO 80045, USA
    Toxicol Lett 205:293-301. 2011
    ..This study could help in identifying countermeasures that alone or in combination, can target the unveiled pathways for reducing skin injury in humans by SM...
  3. pmc Silibinin attenuates sulfur mustard analog-induced skin injury by targeting multiple pathways connecting oxidative stress and inflammation
    Neera Tewari-Singh
    Department of Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado, United States of America
    PLoS ONE 7:e46149. 2012
    ..Together, these findings support further optimization of silibinin in HD skin toxicity model to develop a novel effective therapy for skin injuries by vesicants...
  4. pmc Bitter melon juice activates cellular energy sensor AMP-activated protein kinase causing apoptotic death of human pancreatic carcinoma cells
    Manjinder Kaur
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Cancer Center, University of Colorado, Aurora, CO 80045, USA
    Carcinogenesis 34:1585-92. 2013
    ..Overall, BMJ exerts strong anticancer efficacy against human pancreatic carcinoma cells, both in vitro and in vivo, suggesting its clinical usefulness. ..
  5. doi request reprint Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries
    Neera Tewari-Singh
    Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO 80045, USA
    Toxicol Appl Pharmacol 264:23-31. 2012
    ....
  6. doi request reprint Absence of a p53 allele delays nitrogen mustard-induced early apoptosis and inflammation of murine skin
    Swetha Inturi
    Department of Pharmaceutical Sciences, University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, 12850 E Montview Blvd, Aurora, CO 80045, USA Electronic address
    Toxicology 311:184-90. 2013
    ..Thus, targeting this pathway could be a novel strategy for developing countermeasures against vesicants-induced skin injury. ..
  7. pmc Grape seed extract efficacy against azoxymethane-induced colon tumorigenesis in A/J mice: interlinking miRNA with cytokine signaling and inflammation
    Molly M Derry
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
    Cancer Prev Res (Phila) 6:625-33. 2013
    ....
  8. pmc Clinically-relevant cutaneous lesions by nitrogen mustard: useful biomarkers of vesicants skin injury in SKH-1 hairless and C57BL/6 mice
    Neera Tewari-Singh
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Denver, Aurora, Colorado, United States of America
    PLoS ONE 8:e67557. 2013
    ....
  9. pmc Epigenetic modifications and p21-cyclin B1 nexus in anticancer effect of histone deacetylase inhibitors in combination with silibinin on non-small cell lung cancer cells
    Samiha Mateen
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, USA
    Epigenetics 7:1161-72. 2012
    ..These findings are both novel and highly significant in establishing that HDACi with silibinin would be safe and effective to suppress NSCLC growth...
  10. pmc Generation of reactive oxygen species by grape seed extract causes irreparable DNA damage leading to G2/M arrest and apoptosis selectively in head and neck squamous cell carcinoma cells
    Sangeeta Shrotriya
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado, Aurora, CO 80045, USA
    Carcinogenesis 33:848-58. 2012
    ....
  11. pmc Deletion of p21/Cdkn1a confers protective effect against prostate tumorigenesis in transgenic adenocarcinoma of the mouse prostate model
    Anil K Jain
    Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
    Cell Cycle 12:1598-604. 2013
    ....