Research Topics
| R JahanSummaryAffiliation: University of California Country: USA Publications
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Publications
Treatment of acute ischemic stroke: intravenous and endovascular therapiesReza Jahan
Division of Interventional Neuroradiology, Department of Radiology, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Suite 2129, Box 743730, Los Angeles, CA 90095 7437, USA
Expert Rev Cardiovasc Ther 7:375-87. 2009..In this article, we review the major intravenous and intra-arterial thrombolysis trials and review the mechanical strategies being developed to treat patients with acute ischemic stroke...
An arteriovenous malformation model for stereotactic radiosurgery researchReza Jahan
Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California 90095, USA
Neurosurgery 61:152-9; discussion 159. 2007..To introduce the utilization of a swine arteriovenous malformation (AVM) model for stereotactic radiosurgery research and to describe the morphological changes in the vessels after radiation...- Embolization of arteriovenous malformations with Onyx: clinicopathological experience in 23 patientsR Jahan
Division of Interventional Neuroradiology, Center for the Health Sciences, University of California at Los Angeles School of Medicine, 90095 1721, USA
Neurosurgery 48:984-95; discussion 995-7. 2001..To report our experience in treatment of arteriovenous malformations (AVMs) using a new liquid embolic agent, Onyx (Micro Therapeutics, Inc., Irvine, CA)... - Stereotactic radiosurgery of the rete mirabile in swine: a longitudinal study of histopathological changesReza Jahan
Division of Interventional Neuroradiology, Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
Neurosurgery 58:551-8; discussion 551-8. 2006..The mechanisms of vessel occlusion in arteriovenous malformations has not been extensively evaluated. To better understand these mechanisms, we report histopathological changes in the swine rete mirabile after stereotactic radiosurgery... - Hyperacute therapy of acute ischemic stroke: intraarterial thrombolysis and mechanical revascularization strategiesReza Jahan
Division of Interventional Neuroradiology, Department of Radiological Sciences, UCLA School of Medicine, Los Angeles, CA 90095 1721, USA
Tech Vasc Interv Radiol 8:87-91. 2005..In this report we review the major intraarterial thrombolysis trials and review the mechanical strategies being developed to treat patients with acute ischemic stroke... - Hyperacute therapy of ischemic stroke: intravenous thrombolysisReza Jahan
Division of Interventional Neuroradiology, Department of Radiological Sciences, UCLA School of Medicine, Los Angeles, CA 90095 1721, USA
Tech Vasc Interv Radiol 8:81-6. 2005..In this article we review the major intravenous thrombolysis trials leading to approval of intravenous recombinant tissue plasminogen activator, the only FDA approved treatment available today for acute ischemic stroke... - Solitaire flow-restoration device for treatment of acute ischemic stroke: safety and recanalization efficacy study in a swine vessel occlusion modelR Jahan
Department of Radiology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
AJNR Am J Neuroradiol 31:1938-43. 2010..My purpose was to evaluate the recanalization efficacy and safety of the Solitaire FR Revascularization Device in a swine vessel occlusion model... 
Angiography reveals that fluid-attenuated inversion recovery vascular hyperintensities are due to slow flow, not thrombusN Sanossian
Stroke Center and Department of Neurology, University of Southern California, Los Angeles, CA 90033, USA
AJNR Am J Neuroradiol 30:564-8. 2009..We studied the pathophysiologic and hemodynamic correlates of FVH on conventional angiography and concurrent MR imaging sequences...- Higher rates of mortality but not morbidity follow intracranial mechanical thrombectomy in the elderlyYince Loh
Division of Neurosurgery, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, California, USA
AJNR Am J Neuroradiol 31:1181-5. 2010..Mechanical thrombectomy is a promising means of recanalizing acute cerebrovascular occlusions in certain situations. We sought to determine if increasing age adversely affects prognosis... - Partial recanalization of concomitant internal carotid-middle cerebral arterial occlusions promotes distal recanalization of residual thrombus within 24 hY Loh
Division of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
J Neurointerv Surg 3:38-42. 2011..Successful recanalization of the proximal aspect of the occlusion may allow for endogenous thrombolysis and facilitate further endogenous recanalization of any residual MCA occlusion... - Intra-arterial thrombolysis for acute stroke in patients 80 and older: a comparison of results in patients younger than 80 yearsD Kim
University of California at Los Angeles Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, CA, USA
AJNR Am J Neuroradiol 28:159-63. 2007..The purpose of this study was to compare the baseline characteristics, complications, and outcomes between intra-arterially treated ischemic stroke patients aged > or = 80 years and their younger counterparts... - Statin enhancement of collateralization in acute strokeB Ovbiagele
Department of Neurology, UCLA Medical Center, Los Angeles, CA 90095, USA
Neurology 68:2129-31. 2007..After adjusting for covariates, the statin-treated group had significantly higher collateral scores than non-statin users, suggesting an association between statin use and better collateralization during acute stroke... - Diffusion-perfusion MRI characterization of post-recanalization hyperperfusion in humansC S Kidwell
UCLA Stroke Center, UCLA Medical Center, Los Angeles, CA 90095, USA
Neurology 57:2015-21. 2001..Animal and human studies have demonstrated that postischemic hyperperfusion may occur both early and late timepoints following acute cerebral ischemia... - Initial clinical experience with matrix detachable coils for the treatment of intracranial aneurysmsYuichi Murayama
Division of Interventional Neuroradiology, David Geffen School of Medicine, University of California, Los Angeles, California 90095 1721, USA
J Neurosurg 105:192-9. 2006..It has a platinum core covered with a bioactive, bioabsorbable polymer (polyglycolic acid/lactide). The authors report on their initial midterm clinical experience with the first-generation Matrix detachable coil... - Perfusion-weighted magnetic resonance imaging thresholds identifying core, irreversibly infarcted tissueLudy C Shih
UCLA Stroke Center, UCLA Medical Center, Los Angeles, Calif, USA
Stroke 34:1425-30. 2003..Pretreatment perfusion MRI offers promise as a means to differentiate core from penumbral tissues... - Endovascular thrombectomy for acute ischemic stroke in failed intravenous tissue plasminogen activator versus non-intravenous tissue plasminogen activator patients: revascularization and outcomes stratified by the site of arterial occlusionsZhong Song Shi
Division of Interventional Neuroradiology, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Los Angeles, CA 90095 7437, USA
Stroke 41:1185-92. 2010..We compared patients treated by mechanical embolus removal in cerebral ischemia (MERCI) thrombectomy after failed IV tPA with those treated with thrombectomy alone... - Basal ganglionic infarction before mechanical thrombectomy predicts poor outcomeYince Loh
Division of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, Calif, USA
Stroke 40:3315-20. 2009..Use of mechanical thrombectomy for acute cerebrovascular occlusions is increasing. Preintervention MRI patterns may be helpful in predicting prognosis... - Detection and characterization of very small cerebral aneurysms by using 2D and 3D helical CT angiographyJ Pablo Villablanca
Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA 90095, USA
AJNR Am J Neuroradiol 23:1187-98. 2002..High quality, noninvasive CTA aneurysm detection and characterization can be performed using routine clinical CT scanners and commercially available image processing workstations... - Endovascular mechanical clot retrieval in a broad ischemic stroke cohortD Kim
University of California at Los Angeles Stroke Center, Los Angeles, CA, USA
AJNR Am J Neuroradiol 27:2048-52. 2006..Our aim was to describe an expanded experience with endovascular mechanical embolectomy in a broad group of patients, including those not meeting entry criteria for the MERCI multicenter trials... - Management of giant middle cerebral artery aneurysms with incorporated branches: partial endovascular coiling or combined extracranial-intracranial bypass--a team approachZhong Song Shi
Division of Interventional Neuroradiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles 90095 1721, California, USA
Neurosurgery 65:121-9; discussion 129-31. 2009..Our goal was to assess the long-term anatomic and clinical outcomes in patients with giant middle cerebral artery (MCA) aneurysms treated by endovascular coil embolization alone or in combination with cerebral revascularization... - Volume-rendered helical computerized tomography angiography in the detection and characterization of intracranial aneurysmsJ P Villablanca
Department of Neurosurgery, Radiological Sciences, University of California, Los Angeles 90095, USA
J Neurosurg 93:254-64. 2000..The authors compared the abilities of CT angiography, digital subtraction (DS) angiography, and three-dimensional time-of-flight magnetic resonance (MR) angiography to characterize aneurysms... - Recanalization rates decrease with increasing thrombectomy attemptsY Loh
Division of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
AJNR Am J Neuroradiol 31:935-9. 2010..We sought to determine whether there is an optimum number of retrieval attempts that yields the highest recanalization rates and after which the probability of success decreases... - Intraarterial thrombolysis for acute ischemic strokeReza Jahan
Division of Interventional Neuroradiology, UCLA School of Medicine, Los Angeles, California, USA
Adv Neurol 92:383-7. 2003 - Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trialWade S Smith
Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0114, USA
Stroke 39:1205-12. 2008..Enhancements in embolectomy device design may improve recanalization rates... - Collateral failure? Late mechanical thrombectomy after failed intravenous thrombolysisDavid S Liebeskind
Department of Neurology, UCLA Stroke Center, Los Angeles, California 90095, USA
J Neuroimaging 20:78-82. 2010..Delayed collateral failure may extend the time window for revascularization, even after failed intravenous thrombolysis... - Transvenous treatment of spontaneous dural carotid-cavernous fistulas using a combination of detachable coils and OnyxS Suzuki
Division of Interventional Neuroradiology, Department of Radiological Sciences, UCLA School of Medicine, University of California-Los Angeles, 10833 LeConte Avenue, Los Angeles, CA 90095, USA
AJNR Am J Neuroradiol 27:1346-9. 2006..This report suggests that the controlled and excellent penetration of Onyx is superb for blocking the intricate communication of dural carotid-cavernous fistulas... - Influence of gender on outcomes after intra-arterial thrombolysis for acute ischemic strokeS H Shah
Department of Neurology, UCLA Medical Center, USA
Neurology 66:1745-6. 2006.... - Therapeutic management of cerebral arteriovenous malformations. Present role of interventional neuroradiologyF Vinuela
Division of interventional Neuroradiology DINR, UCLA School of Medicine and Medical Center San Francisco, USA
Interv Neuroradiol 11:13-29. 2005..They have become essential in the therapeutic management of avms closely related to cerebral eloquent areas (figure 1)... - Endovascular treatment of middle cerebral artery aneurysms with detachable coils: angiographic and clinical outcomes in 115 consecutive patientsShuichi Suzuki
Division of Interventional Neuroradiology, Department of Radiological Sciences, University of California, Los Angeles School of Medicine, Los Angeles, California 90095 1721, USA
Neurosurgery 64:876-88; discussion 888-9. 2009..We retrospectively reviewed the anatomic and clinical outcomes of patients with MCA aneurysms who underwent endovascular treatment at our institution... - Impact of hyperlipidemia and statins on ischemic stroke outcomes after intra-arterial fibrinolysis and percutaneous mechanical embolectomyLucas Restrepo
Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, California 90095, USA
Cerebrovasc Dis 28:384-90. 2009..The determinants of the final clinical outcome after endovascular treatment have been understudied. We investigated the effects of hyperlipidemia and statins on acute ischemic stroke outcomes after endovascular procedures... - Intravascular polymer material after coil embolization of a giant cerebral aneurysmRupal I Mehta
Department of Pathology and Laboratory Medicine, University of California, Los Angeles, CA 90095, USA
Hum Pathol 40:1803-7. 2009..Polymer gel is now widely used on several medical devices for interventional procedures worldwide, and we suspect that risks associated with iatrogenic embolization of this substance are underrecognized... - Treatment of brain arteriovenous malformations with high-flow arteriovenous fistulas: risk and complications associated with endovascular embolization in multimodality treatment. Clinical articleIchiro Yuki
Division of Interventional Neuroradiology, Department of Radiological Sciences, UCLA Medical Center and David Geffen School of Medicine, University of California, Los Angeles, California 90095 1721, USA
J Neurosurg 113:715-22. 2010..The purpose of this study was to examine the outcomes of multimodality treatment of AVMs in association with a large arteriovenous fistula (AVF), with a special focus on endovascular embolization and its associated complications... - Endovascular coiling of intracranial aneurysms in elderly patients: report of 205 treated aneurysmsNestor R Gonzalez
Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA
Neurosurgery 66:714-20; discussion 720-1. 2010..More elderly patients are presenting with intracranial aneurysms. Many are poor surgical candidates and often undergo endovascular treatment... - Hydrophilic polymer emboli: an under-recognized iatrogenic cause of ischemia and infarctRupal I Mehta
Department of Pathology and Laboratory Medicine Section of Neuropathology, University of California, Los Angeles, CA 90095, USA
Mod Pathol 23:921-30. 2010..Polymer gel is now widely used on several devices for interventional procedures worldwide, and we suspect that complications associated with iatrogenic embolization of this substance are under-recognized... - Clinical outcomes in middle cerebral artery trunk occlusions versus secondary division occlusions after mechanical thrombectomy: pooled analysis of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) and Multi MERCI trialsZhong Song Shi
Division of Interventional Neuroradiology, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Los Angeles, CA 90095 7437, USA
Stroke 41:953-60. 2010..In this analysis, we compared revascularization status and clinical outcomes in patients with angiographically confirmed MCA M1 versus isolated M2 occlusions treated with mechanical thrombectomy using the Merci Retriever devices... - Thrombolysis with plasmin: implications for stroke treatmentVictor J Marder
Division of Hematology Oncology, David Geffen School of Medicine at University of California Los Angeles, Room A3 29 Rehabilitation Building, 1000 Veteran Ave, Los Angeles, CA 90095, USA
Stroke 41:S45-9. 2010..Based on these data and other information, a phase I/IIa clinical trial of plasmin in human middle cerebral artery ischemic stroke has been initiated... - Predictors of subarachnoid hemorrhage in acute ischemic stroke with endovascular therapyZhong Song Shi
Division of Interventional Neuroradiology, David Geffen School of Medicine at UCLA, 757 Westwood Plaza, Los Angeles, CA 90095 7437, USA
Stroke 41:2775-81. 2010..The purpose of this study was to describe the frequency and predictors of SAH in acute ischemic stroke patients treated endovascularly and its impact on clinical outcome... - Safety of intracranial endovascular aneurysm therapy using 3-dimensional rotational angiography: a single-center experienceYince Loh
Division of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
Surg Neurol 69:158-63; discussion 163. 2008..Three-dimensional rotational angiography has recently been implemented in many interventional neuroradiology practices and may assist the endovascular operator in case selection and planning. The end result may be improved safety... - Late secondary ischemic injury in patients receiving intraarterial thrombolysisChelsea S Kidwell
Stroke Center, UCLA Medical Center, 710 Westwood Plaza, Los Angeles, CA 90095, USA
Ann Neurol 52:698-703. 2002..In the future, late secondary tissue injury may become an important therapeutic target for postreperfusion neuroprotective therapies, with treatment efficacy monitored by serial diffusion magnetic resonance imaging... - Guglielmi detachable coil embolization of cerebral aneurysms: 11 years' experienceYuichi Murayama
Division of Interventional Neuroradiology and Neurosurgery, University of California Medical Center, David Geffen School of Medicine at the University of California, Los Angeles, California 90095 1721, USA
J Neurosurg 98:959-66. 2003..The authors report on their 11 years' experience with embolization of cerebral aneurysms using Guglielmi Detachable Coil (GDC) technology and on the attendant anatomical and clinical outcomes... - Assessment of the patient with hyperacute stroke: imaging and therapyJames M Provenzale
Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710-3808, USA
Radiology 229:347-59. 2003..The goal of such imaging techniques is to monitor successes and complications of recently developed treatments such as thrombolysis... - Treatment of unruptured aneurysms with GDCs: clinical experience with 247 aneurysmsNestor Gonzalez
Divisions of Neurosurgery, University of California, Los Angeles Medical Center, Los Angeles, CA, USA
AJNR Am J Neuroradiol 25:577-83. 2004..9 days. CONCLUSION: GDC technology constitutes safe treatment for unruptured aneurysms, with successful anatomic and clinical results and low complication rates achieved... - Three-dimensional helical computerized tomography angiography in the diagnosis, characterization, and management of middle cerebral artery aneurysms: comparison with conventional angiography and intraoperative findingsJ Pablo Villablanca
Department of Neurosurgery, University of California at Los Angeles, California, USA
J Neurosurg 97:1322-32. 2002.... - Aneurysms of the posterior circulation: detection and treatment planning using volume-rendered three-dimensional helical computerized tomography angiographyJ Pablo Villablanca
Department of Radiological Sciences, University of California at Los Angeles 90095 1721, USA
J Neurosurg 103:1018-29. 2005.... - Challenges in the endovascular treatment of giant intracranial aneurysmsNestor R Gonzalez
Division of Neurosurgery, University of California, Los Angeles Medical Center, Los Angeles, California 90095 7039, USA
Neurosurgery 59:S113-24; discussion S3-13. 2006..The purpose of this study was to evaluate the anatomic and hemodynamic characteristics of these lesions and the current endovascular and combined surgical and endovascular techniques available for their treatment... - Contribution of endovascular therapy to the management of poor-grade aneurysmal subarachnoid hemorrhage: Clinical and angiographic outcomesShuichi Suzuki
Division of Interventional Neuroradiology, Department of Radiological Sciences, University of California at Los Angeles, California 90095 1721, USA
J Neurosurg 105:664-70. 2006..The aim of the present study was to evaluate immediate and long-term angiographic and clinical outcomes in patients with poor-grade SAH treated by endovascular embolization... - Analysis of thrombi retrieved from cerebral arteries of patients with acute ischemic strokeVictor J Marder
Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles Orthopaedic Hospital, 2400 S Flower St, Los Angeles, California 90007, USA
Stroke 37:2086-93. 2006..Information regarding the histological structure of thromboemboli that cause acute stroke provides insight into pathogenesis and clinical management... - Predictors of hemorrhagic transformation in patients receiving intra-arterial thrombolysisChelsea S Kidwell
UCLA Stroke Center, UCLA Medical Center, Los Angeles, Calif 90095, USA
Stroke 33:717-24. 2002..Hemorrhagic transformation (HT) is a major complication of intra-arterial (IA) thrombolytic therapy. Identifying significant predictors of hemorrhage after thrombolysis would be useful in guiding patient selection for IA treatment... - Magnetic resonance imaging detection of microbleeds before thrombolysis: an emerging applicationChelsea S Kidwell
UCLA Stroke Center, Department of Neurology, UCLA Medical Center, Los Angeles, CA 90095, USA
Stroke 33:95-8. 2002.... - Endovascular management of anterior cranial fossa dural arteriovenous malformations. A technical report and anatomical discussionW J Mack
Department of Neurosurgery, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
Interv Neuroradiol 17:93-103. 2011..We discuss the clinical symptoms resulting from the differing venous drainage patterns... - Impact of reperfusion after 3 hours of symptom onset on tissue fate in acute cerebral ischemiaOh Young Bang
Department of Neurology, University of California, Los Angeles, CA, USA
J Neuroimaging 19:317-22. 2009..However, there has been only sparse direct evidence that reperfusion after 3 hours prevents infarct growth... - Autopsy findings after intracranial thrombectomy for acute ischemic stroke: a clinicopathologic study of 5 patientsNicole S Yin
Department of Pathology, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
Stroke 41:938-47. 2010..Various devices (including most extensively the Mechanical Embolus Removal in Cerebral Ischemia [MERCI] Retriever device) have been used for this... - Prediction of hemorrhagic transformation after recanalization therapy using T2*-permeability magnetic resonance imagingOh Young Bang
Department of Neurology, University of California, Los Angeles, Los Angeles, CA, USA
Ann Neurol 62:170-6. 2007..We evaluated the ability of a novel MRI permeability technique to detect baseline derangements predictive of various forms of HT after recanalization therapy... - Access to intra-arterial therapies for acute ischemic stroke: an analysis of the US populationShuichi Suzuki
Department of Radiological Sciences, UCLA School of Medicine, 10833 Le Conte Ave, room B2-188 CHS, Los Angeles, CA 90095-1721, USA
AJNR Am J Neuroradiol 25:1802-6. 2004..These data suggest that interventional therapies that extend the time window for treating acute ischemic stroke could have a major effect on public health and merit further research development and investment... - Intracranial vascular stenosis and occlusive disease: evaluation with CT angiography, MR angiography, and digital subtraction angiographySuzie Bash
Department of Radiology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095, USA
AJNR Am J Neuroradiol 26:1012-21. 2005..CTA has a high interoperator reliability. CTA is superior to DSA in the evaluation of posterior circulation steno-occlusive disease when slow flow is present. CTA results had a significant effect on patient clinical management... - Endovascular treatment of middle cerebral artery aneurysms. Overall perioperative results. Apropos of 113 casesG Guglielmi
Division of Interventional Neuroradiology, UCLA School of Medicine, Los Angeles CA, USA
Interv Neuroradiol 14:241-5. 2008..It must be meticulously planned in all other cases. Endovascular coil treatment of MCA aneurysms is feasible, with acceptable morbi-mortality rates... - Early MRI and outcomes of untreated patients with mild or improving ischemic strokeV Rajajee
UCLA Medical Center, Los Angeles, CA, USA
Neurology 67:980-4. 2006.... - Transarterial embolization of clival dural arteriovenous fistulae using liquid embolic agentsZhong Song Shi
Division of Interventional Neuroradiology, University of California at Los Angeles Medical Center, Los Angeles, California 90095 1721, USA
Neurosurgery 62:408-15; discussion 415. 2008..This report examines the clinical presentation, angiographic findings, endovascular management, and outcome of clival DAVFs. Particular attention was given to safety and efficacy of transarterial embolization using liquid embolic agents... - A brief prehospital stroke severity scale identifies ischemic stroke patients harboring persisting large arterial occlusionsBijen Nazliel
Stroke Center, David Geffen School of Medicine, University of California, Los Angeles, USA
Stroke 39:2264-7. 2008..The Los Angeles Motor Scale (LAMS) is a brief 3-item stroke severity assessment measure designed for prehospital and Emergency Department use... - Lymphomatosis cerebri presenting as a rapidly progressive dementia: clinical, neuroimaging and pathologic findingsR Bakshi
Department of Neurology, UCLA School of Medicine and UCLA Medical Center, Reed Neurological Research Center, Los Angeles, CA, USA
Dement Geriatr Cogn Disord 10:152-7. 1999..We refer to this entity as 'lymphomatosis cerebri' and add it to the differential diagnosis of a rapidly progressive dementia... - Adult pial arteriovenous fistula and superior sagittal sinus stenosis: angiographic evidence for high-flow venopathy at an atypical location. Case reportJoon K Song
Department of Radiology, and Section of Neurovascular Surgery, University of California at Los Angeles School of Medicine and Medical Center, USA
J Neurosurg 96:792-5. 2002.... - MERCI 1: a phase 1 study of Mechanical Embolus Removal in Cerebral IschemiaY Pierre Gobin
Division of Interventional Neuroradiology, Weill Cornell Medical College, New York Presbyterian Hospital, New York, NY 10021, USA
Stroke 35:2848-54. 2004..To report the result of the Mechanical Embolus Removal in Cerebral Ischemia (MERCI) 1 study, a phase 1 trial to evaluate the safety and efficacy of mechanical embolectomy in the cerebral vasculature... - Balloon-assisted transarterial embolization of intracranial dural arteriovenous fistulasZhong Song Shi
Division of Interventional Neuroradiology, University of California at Los Angeles Medical Center, Los Angeles, California, USA
J Neurosurg 110:921-8. 2009..The authors report their preliminary experience using a balloon-assisted technique (BAT) in the transarterial embolization of intracranial dural arteriovenous fistulas (DAVFs)... - Beyond tissue plasminogen activator: mechanical intervention in acute strokeMegan C Leary
Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
Ann Emerg Med 41:838-46. 2003..The purpose of this review is to provide the emergency medicine community with an understanding of these promising and emerging approaches to acute stroke therapy... - Validation of computed tomographic middle cerebral artery "dot"sign: an angiographic correlation studyMegan C Leary
Department of Neurology, Division of Stroke and Cerebrovascular Disease, Palmer 125, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, Mass 02215, USA
Stroke 34:2636-40. 2003..The MCA dot sign has not been validated previously against the gold standard of conventional cerebral angiography... - Acute basilar artery occlusion: diffusion-perfusion MRI characterization of tissue salvage in patients receiving intra-arterial stroke therapiesJill L Ostrem
Department of Neurology, UCLA Medical Center, USA
Stroke 35:e30-4. 2004..Diffusion-perfusion MRI in patients with anterior circulation occlusions has demonstrated salvage of threatened tissue after thrombolytic therapy. Similar studies have not been reported with posterior circulation occlusions... - Middle cerebral artery occlusion in the rabbit using selective angiography: application for assessment of thrombolysisReza Jahan
Stroke 39:1613-5. 2008..Recanalization was achieved rapidly after IA plasmin in 3 of 3 animals. CONCLUSIONS: We describe a new animal model of selective MCA occlusion documented by real-time angiography and used to demonstrate recanalization with IA plasmin... - Thrombolytic toxicity: blood brain barrier disruption in human ischemic strokeChelsea S Kidwell
Department of Neurology, Georgetown University, Washington, DC 20010, USA
Cerebrovasc Dis 25:338-43. 2008..Early barrier opening caused by focal cerebral ischemia in human stroke can be assessed by the presence of gadolinium enhancement of cerebrospinal fluid, termed 'Hyperintense Acute Injury Marker' (HARM)... - Impact of collateral flow on tissue fate in acute ischaemic strokeO Y Bang
Department of Neurology, Samsung Medical Centre, Sungkyunkwan University, Seoul, South Korea
J Neurol Neurosurg Psychiatry 79:625-9. 2008..Collaterals may sustain penumbra prior to recanalisation yet the influence of baseline collateral flow on infarct growth following endovascular therapy remains unknown... - Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trialMarike Zwienenberg-Lee
Department of Neurological Surgery, Children s Hospital of Wisconsin, 999 N 92nd St, Suite 310, Milwaukee, WI 53226, USA
Stroke 39:1759-65. 2008..Prophylactic Transluminal Balloon Angioplasty (pTBA) appeared to prevent delayed ischemic neurological deficit in a pilot study. A phase II multicenter randomized clinical trial was subsequently designed...