W Jagust

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Age effects on atrophy rates of entorhinal cortex and hippocampus
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 27:733-40. 2006
  2. ncbi request reprint Central obesity and the aging brain
    William Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California at Berkeley, 94720, USA
    Arch Neurol 62:1545-8. 2005
  3. pmc Neuropathological basis of magnetic resonance images in aging and dementia
    William J Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 3190, USA
    Ann Neurol 63:72-80. 2008
  4. pmc Apolipoprotein E, not fibrillar β-amyloid, reduces cerebral glucose metabolism in normal aging
    William J Jagust
    Helen Wills Neuroscience Institute, University of California at Berkeley, Berkeley, California 94720 3190, USA
    J Neurosci 32:18227-33. 2012
  5. pmc Vulnerable neural systems and the borderland of brain aging and neurodegeneration
    William Jagust
    Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA 94720 3190, USA
    Neuron 77:219-34. 2013
  6. pmc Molecular neuroimaging in Alzheimer's disease
    William Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720, USA
    NeuroRx 1:206-12. 2004
  7. ncbi request reprint What can imaging reveal about obesity and the brain?
    William Jagust
    School of Public Health, Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720, USA
    Curr Alzheimer Res 4:135-9. 2007
  8. ncbi request reprint What does fluorodeoxyglucose PET imaging add to a clinical diagnosis of dementia?
    W Jagust
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 3190, USA
    Neurology 69:871-7. 2007
  9. pmc Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects
    E C Mormino
    Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA
    Brain 132:1310-23. 2009
  10. pmc Mapping brain beta-amyloid
    William Jagust
    School of Public Health, University of California, Berkeley, CA 94720 3190, USA
    Curr Opin Neurol 22:356-61. 2009

Detail Information

Publications59

  1. pmc Age effects on atrophy rates of entorhinal cortex and hippocampus
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 27:733-40. 2006
    ..In conclusion, age and presence of lacunes should be taken into consideration in imaging studies of CN subjects and AD patients to predict AD progression and assess the response to treatment trials...
  2. ncbi request reprint Central obesity and the aging brain
    William Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California at Berkeley, 94720, USA
    Arch Neurol 62:1545-8. 2005
    ..Central adiposity as an indicator of visceral fat is linked to vascular and metabolic factors that in turn are related to cognitive decline and dementia...
  3. pmc Neuropathological basis of magnetic resonance images in aging and dementia
    William J Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 3190, USA
    Ann Neurol 63:72-80. 2008
    ..Magnetic resonance (MR) imaging is used widely for assessment of patients with cognitive impairment, but the pathological correlates are unclear, especially when multiple pathologies are present...
  4. pmc Apolipoprotein E, not fibrillar β-amyloid, reduces cerebral glucose metabolism in normal aging
    William J Jagust
    Helen Wills Neuroscience Institute, University of California at Berkeley, Berkeley, California 94720 3190, USA
    J Neurosci 32:18227-33. 2012
    ..These results show that ApoE genotype, and not aggregated fibrillar forms of Aβ, contributes to reduced glucose metabolism in aging and adds to a growing list of neural consequences of ApoE that do not appear to be related to Aβ...
  5. pmc Vulnerable neural systems and the borderland of brain aging and neurodegeneration
    William Jagust
    Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA 94720 3190, USA
    Neuron 77:219-34. 2013
    ..By focusing on the fundamental causes of neural system vulnerability, the prevention or treatment of a wide range of late-life neural dysfunction might be possible...
  6. pmc Molecular neuroimaging in Alzheimer's disease
    William Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, California 94720, USA
    NeuroRx 1:206-12. 2004
    ..Despite these unanswered questions, PET and SPECT may have application as biomarkers for AD in a number of clinical and research settings, especially in academic centers, where most of the existing studies have been done...
  7. ncbi request reprint What can imaging reveal about obesity and the brain?
    William Jagust
    School of Public Health, Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720, USA
    Curr Alzheimer Res 4:135-9. 2007
    ..Application of additional imaging methods could help to establish the pathway through which obesity produces cognitive decline and dementia...
  8. ncbi request reprint What does fluorodeoxyglucose PET imaging add to a clinical diagnosis of dementia?
    W Jagust
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 3190, USA
    Neurology 69:871-7. 2007
    ..Few studies have compared the accuracy of [(18)F]fluorodeoxyglucose (FDG) PET to the accuracy of clinical and pathologic diagnosis in dementia patients...
  9. pmc Episodic memory loss is related to hippocampal-mediated beta-amyloid deposition in elderly subjects
    E C Mormino
    Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA
    Brain 132:1310-23. 2009
    ..This pattern suggests that declining EM in older individuals may be caused by Abeta-induced hippocampus atrophy...
  10. pmc Mapping brain beta-amyloid
    William Jagust
    School of Public Health, University of California, Berkeley, CA 94720 3190, USA
    Curr Opin Neurol 22:356-61. 2009
    ....
  11. pmc Lifespan brain activity, β-amyloid, and Alzheimer's disease
    William J Jagust
    Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA 94720, USA
    Trends Cogn Sci 15:520-6. 2011
    ..The aggregated findings unify observations from cellular and molecular studies with human cognitive neuroscience to reveal potential mechanisms of AD development...
  12. pmc The Alzheimer's Disease Neuroimaging Initiative positron emission tomography core
    William J Jagust
    Helen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA, USA
    Alzheimers Dement 6:221-9. 2010
    ..This is a progress report of the Alzheimer's Disease Neuroimaging Initiative (ADNI) positron emission tomography (PET) Core...
  13. ncbi request reprint Dementia: finding the signals in the noise
    William Jagust
    School of Public Health and Helen Wills Neuroscience Institute, University of California, Berkeley, University of California, Berkeley, CA 94720 3190, USA
    Lancet Neurol 4:10-1. 2005
  14. pmc Relationships between biomarkers in aging and dementia
    W J Jagust
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94620, USA
    Neurology 73:1193-9. 2009
    ..Relationships between biomarkers and with disease severity are incompletely understood...
  15. ncbi request reprint Amyloid + activation = Alzheimer's?
    William Jagust
    Helen Wills Neuroscience Institute, University of California, Berkeley, 132 Barker Hall, Berkeley, CA 94720 3190, USA
    Neuron 63:141-3. 2009
    ....
  16. pmc Cognitive and anatomic contributions of metabolic decline in Alzheimer disease and cerebrovascular disease
    Beth Kuczynski
    Helen Wills Neuroscience Institute and the Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA
    Arch Neurol 65:650-5. 2008
    ..Understanding how each disease contributes to dementia is essential from both a pathophysiologic and diagnostic perspective...
  17. ncbi request reprint Amyloid imaging in distinguishing atypical prion disease from Alzheimer disease
    A L Boxer
    Memory and Aging Center, Department of Neurology, University of California, San Francisco, CA 94143 1207, USA
    Neurology 69:283-90. 2007
    ..To compare the in vivo uptake of two amyloid-binding PET agents, PIB and FDDNP, in human subjects with a prion protein (PrP) gene (PRNP) mutation that produces a clinical syndrome similar to Alzheimer disease (AD)...
  18. pmc White matter integrity and cortical metabolic associations in aging and dementia
    Beth Kuczynski
    Helen Wills Neuroscience Institute, University of California at Berkeley, USA
    Alzheimers Dement 6:54-62. 2010
    ..This report investigated how regional white matter integrity (measured as fractional anisotropy [FA]) relates to brain metabolism, to unravel the complex relationship between white matter changes and brain metabolism...
  19. ncbi request reprint Brain imaging evidence of preclinical Alzheimer's disease in normal aging
    William Jagust
    School of Public Health, University of California, Berkeley, USA
    Ann Neurol 59:673-81. 2006
    ..This study was designed to test the hypothesis that baseline glucose metabolism and medial temporal lobe brain volumes are predictive of cognitive decline in normal older people...
  20. pmc Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative
    Owen Carmichael
    Department of Neurology, School of Medicine, University of California, Davis, CA, USA
    Arch Neurol 67:1370-8. 2010
    ....
  21. pmc Degree of discrepancy between self and other-reported everyday functioning by cognitive status: dementia, mild cognitive impairment, and healthy elders
    Sarah Tomaszewski Farias
    Department of Neurology, School of Public Health, University of California Davis, 4860 Y Street, Sacramento, CA 95817, USA
    Int J Geriatr Psychiatry 20:827-34. 2005
    ..In this study we examined whether degree of discrepancy between patient and informant-reported everyday functioning was associated with cognitive status...
  22. pmc The measurement of everyday cognition (ECog): scale development and psychometric properties
    Sarah Tomaszewski Farias
    Department of Neurology, University of California, CA 95817, USA
    Neuropsychology 22:531-44. 2008
    ..Different subtypes of MCI also showed different patterns. Results suggest the ECog shows promise as a useful tool for the measurement of general and domain-specific everyday functions in the elderly...
  23. pmc Clinical Core of the Alzheimer's Disease Neuroimaging Initiative: progress and plans
    Paul S Aisen
    Department of Neurosciences, University of California San Diego, CA, USA
    Alzheimers Dement 6:239-46. 2010
    ..The resulting data would provide valuable data on the earliest stages of AD, and support the development of interventions in these critically important populations...
  24. pmc Requiring an amyloid-beta1-42 biomarker for prodromal Alzheimer's disease or mild cognitive impairment does not lead to more efficient clinical trials
    Lon S Schneider
    Department of Psychiatry, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Alzheimers Dement 6:367-77. 2010
    ....
  25. pmc The Alzheimer's disease neuroimaging initiative
    Susanne G Mueller
    Department of Radiology, University of California, San Francisco, CA, USA
    Neuroimaging Clin N Am 15:869-77, xi-xii. 2005
    ..The Alzheimer's Disease Neuroimaging Initiative will help identify clinical, neuroimaging, and biomarker outcome measures that provide the highest power for measurement of longitudinal changes and for prediction of transitions...
  26. pmc Association of depressed mood and mortality in older adults with and without cognitive impairment in a prospective naturalistic study
    Helen Lavretsky
    Department of Psychiatry, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Psychiatry 167:589-97. 2010
    ....
  27. pmc An inverse association of cardiovascular risk and frontal lobe glucose metabolism
    B Kuczynski
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720, USA
    Neurology 72:738-43. 2009
    ..To investigate associations between vascular risk profile and cerebral glucose metabolism...
  28. ncbi request reprint SPECT perfusion imaging in the diagnosis of Alzheimer's disease: a clinical-pathologic study
    W Jagust
    Department of Neurology, University of California, Davis Medical Center, Sacramento 95817, USA
    Neurology 56:950-6. 2001
    ..CONCLUSIONS: In the evaluation of dementia, SPECT imaging can provide clinically useful information indicating the presence of AD in addition to the information that is obtained from clinical evaluation...
  29. ncbi request reprint Working memory capacity predicts dopamine synthesis capacity in the human striatum
    Roshan Cools
    Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720 3190, USA
    J Neurosci 28:1208-12. 2008
    ....
  30. ncbi request reprint Estrogen- and tamoxifen-associated effects on brain structure and function
    Jamie L Eberling
    Department of Neurology and Center for Neuroscience, University of California, Davis, CA 95616, USA
    Neuroimage 21:364-71. 2004
    ..The ERT- group had hippocampal volumes that were intermediate to the other two groups. These findings provide physiological and anatomical evidence for neuroprotective effects of estrogen...
  31. ncbi request reprint Enhanced cutaneous vascular response in AD subjects under donepezil therapy
    Jonathan S Maltz
    Department of Nuclear Medicine and Functional Imaging, Ernest O Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA
    Neurobiol Aging 25:475-81. 2004
    ..We sought to replicate these observations and further identify peripheral vascular components of AD pathology...
  32. ncbi request reprint A comparison of classification methods for differentiating fronto-temporal dementia from Alzheimer's disease using FDG-PET imaging
    Roger Higdon
    University of Washington, Seattle, USA
    Stat Med 23:315-26. 2004
    ..Methods using PLS appear to be more successful. Averaging or using VOI data may also be helpful...
  33. ncbi request reprint Risk factors for mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 2
    Oscar L Lopez
    Departments of Neurology and Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA
    Arch Neurol 60:1394-9. 2003
    ..To examine the risk factors for mild cognitive impairment (MCI) in a longitudinal population study-the Cardiovascular Health Study Cognition Study...
  34. ncbi request reprint Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging
    Joshua W Miller
    Department of Medical Pathology, School of Medicine, University of California, Davis, USA
    Am J Clin Nutr 78:441-7. 2003
    ....
  35. ncbi request reprint Prevalence of dementia in older latinos: the influence of type 2 diabetes mellitus, stroke and genetic factors
    Mary N Haan
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, Michigan 48109, USA
    J Am Geriatr Soc 51:169-77. 2003
    ..To estimate dementia prevalence in older Mexican Americans, determine the distribution of dementia by etiology, and evaluate the contribution of type 2 diabetes mellitus, stroke, and apolipoprotein E (ApoE) genotype to dementia...
  36. ncbi request reprint Prevalence and classification of mild cognitive impairment in the Cardiovascular Health Study Cognition Study: part 1
    Oscar L Lopez
    Departments of Neurology and Psychiatry, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA
    Arch Neurol 60:1385-9. 2003
    ..To examine the prevalence of mild cognitive impairment (MCI) and its diagnostic classification in the Cardiovascular Health Study (CHS) Cognition Study...
  37. ncbi request reprint Brain function and cognition in a community sample of elderly Latinos
    William J Jagust
    Department of Neurology, University of California Davis Medical Center, 4860 Y Street, Suite 3700, Sacramento, CA 95817, USA
    Neurology 59:378-83. 2002
    ..This study was designed to extend this finding to individuals selected from a population-based cohort of Mexican Americans with a wide spectrum of cognitive ability...
  38. pmc Quantitative magnetic resonance imaging differences between Alzheimer disease with and without subcortical lacunes
    Yuan Yu Hsu
    Department of Veterans Affairs Medical Center, Magnetic Resonance Unit, San Francisco, California, USA
    Alzheimer Dis Assoc Disord 16:58-64. 2002
    ..In conclusion, the presence of subcortical lacunes in those with AD is associated with more WM lesions and ventriculomegaly but not with cortical atrophy...
  39. pmc Everyday functioning in relation to cognitive functioning and neuroimaging in community-dwelling Hispanic and non-Hispanic older adults
    Sarah Tomaszewski Farias
    Department of Neurology, School of Medicine, University of California, Davis, USA
    J Int Neuropsychol Soc 10:342-54. 2004
    ..The relationships between cognitive variables and functional status, as well as between the imaging variables and the IQCODE, did not differ across language-ethnic groups...
  40. ncbi request reprint FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease
    Norman L Foster
    Center for Alzheimer s Care, Imaging and Research and Department of Neurology, University of Utah, USA
    Brain 130:2616-35. 2007
    ..FDG-PET adds important information that appropriately increases diagnostic confidence, even among experienced dementia specialists...
  41. ncbi request reprint Clinical and neuropsychological features in autopsy-defined vascular dementia
    Bruce R Reed
    Alzheimer s Disease Center, University of California, Davis 94553, USA
    Clin Neuropsychol 18:63-74. 2004
    ..A illustrative case example is included. We conclude that the profile of cognitive impairment in IVD is highly variable, but that in clinical settings neuropsychological readings may contribute to the differential diagnosis of dementia...
  42. pmc Pattern of cerebral hypoperfusion in Alzheimer disease and mild cognitive impairment measured with arterial spin-labeling MR imaging: initial experience
    Nathan A Johnson
    MR Research Unit, VA Medical Center, 4150 Clement St 114M San Francisco, CA 94107, USA
    Radiology 234:851-9. 2005
    ....
  43. pmc Different mechanisms of episodic memory failure in mild cognitive impairment
    Christine Wu Nordahl
    Center for Neuroscience, University of California at Davis, Davis, CA, USA
    Neuropsychologia 43:1688-97. 2005
    ..Although both syndromes are associated with episodic memory deficits, CVD is additionally associated with working memory and executive control deficits...
  44. ncbi request reprint Effects of white matter lesions and lacunes on cortical function
    Bruce R Reed
    University of California Davis Alzheimer s Disease Center, Martinez, CA 94553, USA
    Arch Neurol 61:1545-50. 2004
    ..Whether small-vessel disease in fact predominantly affects the frontal lobes is not well documented...
  45. ncbi request reprint Low folate status is associated with impaired cognitive function and dementia in the Sacramento Area Latino Study on Aging
    Marisa I Ramos
    School of Medicine, Department of Medical Pathology, University of California, Davis, USA
    Am J Clin Nutr 82:1346-52. 2005
    ..Since 1998, grain products in the United States have been fortified with folic acid, which has reduced the prevalence of folate deficiency and hyperhomocysteinemia...
  46. ncbi request reprint Bilateral thalamic lesions affect recollection- and familiarity-based recognition memory judgments
    Mark M Kishiyama
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94728 3190, USA
    Cortex 41:778-88. 2005
    ..The results are in agreement with models indicating that the anteromedial thalamus is important for both recollection- and familiarity-based recognition memory...
  47. ncbi request reprint White matter lesions are associated with cortical atrophy more than entorhinal and hippocampal atrophy
    An Tao Du
    Magnetic Resonance Unit 114M, Department of Veterans Affairs Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Neurobiol Aging 26:553-9. 2005
    ..Further, AD pathology and subcortical vascular disease may independently affect cortical atrophy...
  48. pmc White matter changes compromise prefrontal cortex function in healthy elderly individuals
    Christine Wu Nordahl
    University of California at Davis, Sacramento, CA 95817, USA
    J Cogn Neurosci 18:418-29. 2006
    ..These results suggest that disruption of white matter tracts, especially within the PFC, may be a mechanism for age-related changes in memory functioning...
  49. pmc Homocysteine, B vitamins, and the incidence of dementia and cognitive impairment: results from the Sacramento Area Latino Study on Aging
    Mary N Haan
    Epidemiology Program, School of Public Health, University of Michigan, Ann Arbor, MI 48104, USA
    Am J Clin Nutr 85:511-7. 2007
    ..High concentrations of homocysteine have been linked to a greater risk of Alzheimer disease, dementia, and cognitive decline...
  50. pmc Effects of Alzheimer disease on fronto-parietal brain N-acetyl aspartate and myo-inositol using magnetic resonance spectroscopic imaging
    Xiaoping Zhu
    Department of Radiology, VA Medical Center, University of California, San Francisco, CA 94121, USA
    Alzheimer Dis Assoc Disord 20:77-85. 2006
    ..However, the NAA and mI changes are not correlated with each other, suggesting that they represent different processes that might help staging of AD...
  51. pmc Automated template-based PET region of interest analyses in the aging brain
    Felice T Sun
    Helen Wills Neuroscience Institute, School of Public Health, University of California, 118 Barker Hall, Berkeley, CA 94720, USA
    Neuroimage 34:608-17. 2007
    ....
  52. pmc Cognitive impact of subcortical vascular and Alzheimer's disease pathology
    Helena C Chui
    Department of Neurology, University of Southern California, Los Angeles, USA
    Ann Neurol 60:677-87. 2006
    ..To assess the interactions among three types of pathology (ie, cerebrovascular disease, hippocampal sclerosis [HS], and Alzheimer's disease [AD]), cognitive status, and apolipoprotein E genotype...
  53. ncbi request reprint Profiles of neuropsychological impairment in autopsy-defined Alzheimer's disease and cerebrovascular disease
    Bruce R Reed
    University of California, Davis, CA, USA
    Brain 130:731-9. 2007
    ....
  54. ncbi request reprint Correlates of memory function in community-dwelling elderly: the importance of white matter hyperintensities
    Christopher I Petkov
    Center for Neuroscience, University of California at Davis, 95616, USA
    J Int Neuropsychol Soc 10:371-81. 2004
    ..We conclude that WMH are an important pathological substrate that affects certain memory functions in normal individuals and those with mild memory loss and discuss how tasks associated with WMH may rely upon frontal lobe function...
  55. ncbi request reprint Effect of extrapyramidal signs and Lewy bodies on survival in patients with Alzheimer disease
    Mary N Haan
    Department of Epidemiology, University of Michigan, School of Public Health, 109 S Observatory St, Ann Arbor, MI 48109 2029, USA
    Arch Neurol 59:588-93. 2002
    ..Lewy bodies found at autopsy are not always correlated with EPSs during late life...
  56. pmc Anatomical mapping of white matter hyperintensities (WMH): exploring the relationships between periventricular WMH, deep WMH, and total WMH burden
    Charles DeCarli
    Department of Neurology, University of California at Davis, Davis, Calif, USA
    Stroke 36:50-5. 2005
    ..Separate pathophysiologies and behavioral consequences are often attributed to these 2 classes of WMH. However, evidence to support these empirical distinctions has not been rigorously sought...
  57. pmc Hippocampal volume and retention in Alzheimer's disease
    Joel H Kramer
    Department of Neurology, University of California at San Francisco, 94143, USA
    J Int Neuropsychol Soc 10:639-43. 2004
    ..Results suggest that the role of the hippocampus is relatively specific to the consolidation of new memories...
  58. ncbi request reprint Imaging Interactions between Alzheimer's disease and cerebrovascular disease
    Christine C Wu
    Department of Neurology, University of California Davis, 4860 Y Street, Sacramento, CA 95616, USA
    Ann N Y Acad Sci 977:403-10. 2002
    ..In this article, we review two recent studies from our laboratory that use MRI and PET to begin to reveal the nature and mechanisms of the relationship between AD, CVD, and dementia...

Research Grants11

  1. Neural and Biochemical Mechanisms of Cognitive Aging
    William J Jagust; Fiscal Year: 2010
    ..This is important both for understanding relationships between AD and normal aging, and for developing ways of optimizing brain function in aging. ..
  2. Neural and Biochemical Mechanisms of Cognitive Aging
    William Jagust; Fiscal Year: 2009
    ..This is important both for understanding relationships between AD and normal aging, and for developing ways of optimizing brain function in aging. ..
  3. Effects of Chemotherapy on Brain Function
    William Jagust; Fiscal Year: 2009
    ..They are also relevant to the overall mission of the NIH because of the negative impact that cognitive dysfunction has on quality of life. ..
  4. Amyloid Imaging in Frontotemporal Dementia and Alzheimer's Disease
    William Jagust; Fiscal Year: 2009
    ..PIB could become a diagnostic tool that is useful in diagnosing AD and FTLD during life. This will be especially important as new treatments for both disorders are developed. ..
  5. Molecular and Functional Imaging of Age Related Cognitive Decline
    William Jagust; Fiscal Year: 2009
    ....
  6. Molecular and Functional Imaging of Age Related Cognitive Decline
    William Jagust; Fiscal Year: 2008
    ....
  7. Amyloid Imaging in Frontotemporal Dementia and Alzheimer's Disease
    William Jagust; Fiscal Year: 2008
    ..PIB could become a diagnostic tool that is useful in diagnosing AD and FTLD during life. This will be especially important as new treatments for both disorders are developed. ..
  8. Amyloid Imaging in Frontotemporal Dementia and Alzheimer's Disease
    William Jagust; Fiscal Year: 2007
    ..PIB could become a diagnostic tool that is useful in diagnosing AD and FTLD during life. This will be especially important as new treatments for both disorders are developed. ..
  9. Molecular and Functional Imaging of Age Related Cognitive Decline
    William Jagust; Fiscal Year: 2007
    ....
  10. Effects of Chemotherapy on Brain Function
    William J Jagust; Fiscal Year: 2010
    ..They are also relevant to the overall mission of the NIH because of the negative impact that cognitive dysfunction has on quality of life. ..