Research Topics
| Jay JagannathanSummaryAffiliation: University of Virginia Country: USA Publications
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Detail Information
Publications
Clinical and pathological characteristics of brain metastasis resected after failed radiosurgeryJay Jagannathan
Department of Neurosurgery, University of Virginia Health Sciences Center, Box 800212, Charlottesville, VA 22902, USA
Neurosurgery 66:208-17. 2010..This study evaluates the tumor histopathology and clinical characteristics of patients who underwent resection of their brain metastasis after failed gamma knife radiosurgery...- Applications of radiotherapy and radiosurgery in the management of pediatric Cushing's disease: a review of the literature and our experienceJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
J Neurooncol 90:117-24. 2008..This paper reviews the effectiveness of radiation in the treatment of pediatric Cushing's disease... 
Evaluation and management of Cushing syndrome in cases of negative sellar magnetic resonance imagingJay Jagannathan
Department of Neurosurgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22908, USA
Neurosurg Focus 23:E3. 2007..Radiosurgery is an effective treatment option in patients with persistent Cushing disease. When a target cannot be found on MR imaging, one can target the entire sellar region with radiosurgery...- Arachnoid diverticula associated with anterior cranial base tumors: technical case reportJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
Neurosurgery 61:E172-3; discussion E173. 2007..When they occur, they often complicate the surgical management of these tumors via a transsphenoidal approach. This report examines the effectiveness of transsphenoidal surgery in the treatment of these rare entities... - Radiographic and clinical outcomes following single-level anterior cervical discectomy and allograft fusion without plate placement or cervical collarJay Jagannathan
Department of Neurological Surgery, University of Virginia Health System, Box 800212, Charlottesville, Virginia 22908, USA
J Neurosurg Spine 8:420-8. 2008..This paper examines a single-surgeon experience with single-level ACDF without use of plates or hard collars in patients with degenerative spondylosis in whom allograft was used as the fusion material... - The posterior cervical foraminotomy in the treatment of cervical disc/osteophyte disease: a single-surgeon experience with a minimum of 5 years' clinical and radiographic follow-upJay Jagannathan
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22902, USA
J Neurosurg Spine 10:347-56. 2009..This study details long-term clinical and radiographic outcomes following single-level posterior cervical foraminotomy for degenerative disc or osteophyte disease... - Gamma Knife radiosurgery to the surgical cavity following resection of brain metastasesJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, VA 22908, USA
J Neurosurg 111:431-8. 2009..This study evaluated the efficacy of postoperative Gamma Knife surgery (GKS) to the tumor cavity following gross-total resection of a brain metastasis... - Gamma knife radiosurgery for acromegaly: outcomes after failed transsphenoidal surgeryJay Jagannathan
Lars Leksell Gamma Knife Center, Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
Neurosurgery 62:1262-9; discussion 1269-70. 2008..This study evaluates the safety and efficacy of gamma knife radiosurgery (GKRS) in patients with a growth hormone-secreting adenoma... - Benign brain tumors: sellar/parasellar tumorsJay Jagannathan
Department of Neurosurgery, University of Virginia Health System, PO Box 800212, Charlottesville, VA 22908 0711, USA
Neurol Clin 25:1231-49, xi. 2007..Less invasive modalities, such as endoscopic transsphenoidal surgery, specific chemotherapeutic drugs, and stereotactic radiosurgery, show promise as adjuvant treatment modalities... - Cosmetic and functional outcomes following paramedian and anterolateral retroperitoneal access in anterior lumbar spine surgeryJay Jagannathan
Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22902, USA
J Neurosurg Spine 9:454-65. 2008.... - Outcomes and management of patients with Cushing's disease without pathological confirmation of tumor resection after transsphenoidal surgeryNader Pouratian
Department of Neurological Surgery, University of Virginia, Box 800212, Charlottesville, Virginia 22903, USA
J Clin Endocrinol Metab 92:3383-8. 2007..The clinical significance of lack of histological confirmation remains unclear... - Computer-assisted frameless stereotaxy in transsphenoidal surgery at a single institution: review of 176 casesJay Jagannathan
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908-00212, USA
Neurosurg Focus 20:E9. 2006..The MR imaging, CT scanning, and fluoroscopic stereotaxy modalities all have unique advantages as well as specific limitations... - Gamma knife radiosurgery for medically and surgically refractory prolactinomasNader Pouratian
Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA
Neurosurgery 59:255-66; discussion 255-66. 2006..Patients with tumors smaller than 3.0 cm3 and who are not receiving dopamine agonist at the time of treatment will likely benefit most... - Perspectives on endoscopic transsphenoidal surgeryJohn A Jane
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
Neurosurg Focus 19:E2. 2005..The authors describe their current endoscopic technique and elucidate the advantages and disadvantages of the pure endoscopic adenomectomy compared with the standard microscopic approach... - High-intensity focused ultrasound surgery of the brain: part 1--A historical perspective with modern applicationsJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22902, USA
Neurosurgery 64:201-10; discussion 210-1. 2009..The remaining 2 articles in this series will focus on the physical principles of modern MRgFUS as well as current and future avenues for investigation... - Gamma Knife surgery for Cushing's diseaseJay Jagannathan
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908 00212, USA
J Neurosurg 106:980-7. 2007..In this study the authors address the efficacy and safety of Gamma Knife surgery (GKS) in patients with adrenocorticotropic hormone-secreting pituitary adenomas... - Genetics of pituitary adenomas: current theories and future implicationsJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
Neurosurg Focus 19:E4. 2005..These tumors can still be extremely difficult to manage, however, and can cause significant morbidity to the patient, both from tumor mass effect and secondary to hormonal imbalances... - History of endoscopic skull base surgery: its evolution and current realityDaniel M Prevedello
Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
J Neurosurg 107:206-13. 2007..This article discusses the history of the endoscope, the pivotal technological advances, and the key figures in the burgeoning field of endoneurosurgery... - Stereotactic radiosurgery for pituitary adenomas: a comprehensive review of indications, techniques and long-term results using the Gamma KnifeJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, Box 800212, Charlottesville, VA 22908, USA
J Neurooncol 92:345-56. 2009..This study reviews the long-term clinical results of stereotactic radiosurgery in the treatment of pituitary adenoma patients... - Low-grade gliomas in older patients: a retrospective analysis of prognostic factorsNader Pouratian
Department of Neurological Surgery, University of Virginia, Box 800212, Charlottesville, VA 22908 0212, USA
J Neurooncol 90:341-50. 2008..Similarities with previous reports of LGG suggest that age should not affect the management of LGG patients. Prospective studies of older patients with LGG are needed to further characterize the optimum management of these patients... - Radiobiology of brain metastasis: applications in stereotactic radiosurgeryJay Jagannathan
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
Neurosurg Focus 22:E4. 2007..In this paper the authors review the radiobiology of brain metastases and stereotactic radiosurgical approaches that can be used to treat these tumors safely... - Radiographic restoration of lumbar alignment after transforaminal lumbar interbody fusionJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22902, USA
Neurosurgery 64:955-63; discussion 963-4. 2009..Transforaminal lumbar interbody fusion (TLIF) is a popular surgical technique in the lumbar spine, but few data exist on change in spinal alignment after the procedure... - Gamma Knife radiosurgery after radiation therapy as an adjunctive treatment for glioblastomaNader Pouratian
Department of Neurological Surgery, University of Virginia, Charlottesville, VA 22908, USA
J Neurooncol 94:409-18. 2009..Moreover, SRS may be a viable alternative to open surgery for aggressive management of GBM at the time of recurrence. Prospective studies of SRS for GBM should focus on these two groups of patients... - Long-term outcomes and prognostic factors in pediatric patients with severe traumatic brain injury and elevated intracranial pressureJay Jagannathan
Department of Neurosurgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
J Neurosurg Pediatr 2:240-9. 2008..The management strategies and outcomes in pediatric patients with elevated intracranial pressure (ICP) following severe traumatic brain injury (TBI) are examined in this study... - Diagnosis and management of pediatric sellar lesionsJay Jagannathan
Department of Neurological Surgery, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
Front Horm Res 34:83-104. 2006..Less invasive modalities such as endoscopic transsphenoidal surgery, and stereotactic radiosurgery have shown promise as primary and adjuvant treatment modalities, respectively... - Inflammatory and dysplastic lesions involving the spineAdam S Kanter
Department of Neurosurgery, University of California, San Francisco, University of California San Francisco Spine Center, 505 Parnassus Avenue, M 779, Box 0112, San Francisco, CA 94143, USA
Neurosurg Clin N Am 19:93-109. 2008..Common signs and symptoms include pain, scoliosis, myelopathy, and weakness. Surgical decision making is based on patient status, comorbidities, and extent of disease... - Relevance of high Ki-67 in pituitary adenomas. Case report and review of the literatureDaniel M Prevedello
Department of Neurological Surgery and Neuropathology, University of Virginia Health System, Charlottesville, Virginia 22908-00212, USA
Neurosurg Focus 19:E11. 2005..The relationships between high Ki-67 LIs and tumor recurrence, invasiveness, and growth velocity in pituitary adenomas are reviewed... - Surgery Insight: the role of surgery in the management of low-grade gliomasNader Pouratian
University of Virginia, Charlottesville, VA, USA
Nat Clin Pract Neurol 3:628-39. 2007..As a result of advances in surgical techniques, the time might now be right to effectively and accurately assess the influence of aggressive surgical resection on the prognosis of low-grade gliomas... - Stereotactic radiosurgery for pituitary adenomas: a review of the literature and our experienceJason P Sheehan
Lars Leksell Gamma Knife Center, Department of Neurological Surgery, Health Sciences Center, University of Virginia, Charlottesville, VA 22908, USA
Front Horm Res 34:185-205. 2006.... - Cellular signaling molecules as therapeutic targets in glioblastoma multiformeJay Jagannathan
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908-00212, USA
Neurosurg Focus 20:E8. 2006..In this article the authors review various cellular and extracellular signaling pathways that may prove promising in the treatment of patients with malignant glioma... - Cervical spine injuries in pediatric athletes: mechanisms and managementJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908-00212, USA
Neurosurg Focus 21:E6. 2006..The aim of this review was to detail the characteristics and management of pediatric cervical spine injury... - Impact of the Accreditation Council for Graduate Medical Education work-hour regulations on neurosurgical resident education and productivityJay Jagannathan
Departments of Neurological Surgery, University of Virginia Health Sciences Center, Charlottesville, Virginia, USA
J Neurosurg 110:820-7. 2009..The authors have evaluated multiple objective surrogate markers of resident performance and quality of training to determine the impact of the 80-hour workweek... - Surgical management of global sagittal deformity in ankylosing spondylitisCharles A Sansur
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22903, USA
Neurosurg Focus 24:E8. 2008..The authors also review current techniques used to treat sagittal-plane deformity, focusing on pedicle subtraction osteotomy at the thoracolumbar junction, as well as cervical extension osteotomy at the cervicothoracic junction... 
Molecular biology of unreresectable meningiomas: implications for new treatments and review of the literatureJay Jagannathan
Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville, Virginia
Skull Base 18:173-87. 2008..Although the relationship between the various factors implicated in tumor development is unknown, understanding these factors will be critical in the treatment of malignant or surgically inaccessible tumors...- Unusual presentation of an adult intramedullary spinal teratoma with diplomyeliaMelike Mut
Department of Neurosurgery, University of Virginia, Charlottesville, VA 22903, USA
Surg Neurol 67:190-4. 2007..Spinal teratomas are rare lesions. The authors present an intramedullary spinal teratoma associated with diplomyelia... - Outcome following decompressive craniectomy in children with severe traumatic brain injury: a 10-year single-center experience with long-term follow upJay Jagannathan
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia 22908, USA
J Neurosurg 106:268-75. 2007..The authors examine the indications for and outcomes following decompressive craniectomy in a single-center pediatric patient population with traumatic brain injury (TBI)... - Iatrogenic spinal deformityJay Jagannathan
Department of Neurosurgery, University of Virginia Health Sciences Center, University of Virginia, Charlottesville, Virginia 22902, USA
Neurosurgery 63:104-16. 2008..However, patients with flat-back syndrome typically require reoperation. A wide variety of reoperative procedures may be performed, depending on the area of the pathological deformity, extent of disease, and patient condition... - Repeat Gamma Knife surgery for incompletely obliterated cerebral arteriovenous malformationsChun Po Yen
Lars Leksell Center for Gamma Surgery, Department of Neurological Surgery, University of Virginia Health Sciences System, Charlottesville, Virginia 22908, USA
Neurosurgery 67:55-64; discussion 64. 2010..The causes of failure after an initial Gamma procedure were studied, along with imaging and clinical outcomes, in a series of 140 patients with cerebral arteriovenous malformations (AVMs) treated with repeat Gamma Knife surgery (GKS)... - Reverse and pseudoreverse cortical sign in thoracolumbar burst fracture: radiologic description and distinction--a propos of three casesVincent Arlet
Division of Spine Surgery, Department of Orthopaedic Surgery, University of Virginia Health Sciences System, P O Box 800159, Charlottesville, VA 22908, USA
Eur Spine J 18:282-7. 2009..Careful analysis of the CT scan and specifically the sagittal reconstruction and MRI can differentiate two separate entities that may correspond to a different severity injury... - Effect of trans sodium crocetinate on brain tumor oxygenation. Laboratory investigationJason Sheehan
Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia, USA
J Neurosurg 111:226-9. 2009..Trans sodium crocetinate (TSC) has been shown to be a radiosensitizer. The goal of this research was to elucidate the underlying mechanism of TSC's radiosensitizing effect... - Evaluation and management of abdominal lymphoceles after anterior lumbar spine surgeryJay Jagannathan
Department of Orthopedic Surgery, University of Virginia Health Sciences Center, Charlottesville, VA 22902, USA
Spine (Phila Pa 1976) 33:E852-7. 2008..Case report... - Review of spinal radiosurgery: a minimally invasive approach for the treatment of spinal and paraspinal metastasesJason P Sheehan
Department of Neurosurgery, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
Neurosurg Focus 25:E18. 2008..Spinal radiosurgery has expanded the neurosurgical treatment armamentarium for patients with spinal and paraspinal metastasis... - Pediatric sellar tumors: diagnostic procedures and managementJay Jagannathan
Department of Neurological Surgery, University of Virginia Health Science Center, Charlottesville, Virginia, USA
Neurosurg Focus 18:E6. 2005..Less invasive methods, such as endoscopic transsphenoidal surgery and stereotactic radiosurgery, have shown promise as primary and adjuvant treatment modalities, respectively... - Long-term survival after gamma knife radiosurgery for primary and metastatic brain tumorsJay Jagannathan
Department of Neurological Surgery, University of Maryland Medical Center, Baltimore, MD 21201-1595, USA
Am J Clin Oncol 27:441-4. 2004..65 of 10), and only 1 patient had a Karnofsky Performance Score of less than 70. We conclude that radiosurgery provides a noninvasive and effective way of controlling brain tumors, while preserving quality of life... - Novel strategy to treat a case of recurrent lymphocytic hypophysitis using rituximabMatthew Schreckinger
Department of Neurosurgery, Wayne State University, Detroit, Michigan 48201, USA
J Neurosurg 116:1318-23. 2012..Rituximab, an anti-CD20 antibody that specifically depletes B lymphocytes, can be an effective treatment strategy for patients with steroid-refractory, B cell-predominant lymphocytic hypophysitis... - Surgical management of cerebellar hemangioblastomas in patients with von Hippel-Lindau diseaseJay Jagannathan
Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892 1414, USA
J Neurosurg 108:210-22. 2008..To examine modern management and outcomes of cerebellar hemangioblastomas in VHL disease, the authors reviewed findings in patients with this disease who underwent resection of cerebellar hemangioblastomas...