Pudur Jagadeeswaran

Summary

Affiliation: University of North Texas
Country: USA

Publications

  1. ncbi request reprint Zebrafish: from hematology to hydrology
    P Jagadeeswaran
    Department of Biological Sciences, University of North Texas, Denton, TX 76203, USA
    J Thromb Haemost 5:300-4. 2007
  2. pmc Zebrafish thrombocytes: functions and origins
    Gauri Khandekar
    Department of Biological Sciences, University of North Texas, Denton, TX 76203 5017, USA
    Adv Hematol 2012:857058. 2012
  3. pmc Evolution of primary hemostasis in early vertebrates
    Seongcheol Kim
    Department of Biological Sciences, University of North Texas, Denton, Texas, USA
    PLoS ONE 4:e8403. 2009
  4. pmc Loss of GATA1 and gain of FLI1 expression during thrombocyte maturation
    Pudur Jagadeeswaran
    Department of Biological Sciences, University of North Texas, Denton, 76203, USA
    Blood Cells Mol Dis 44:175-80. 2010
  5. doi request reprint Role of zebrafish thrombocyte and non-thrombocyte microparticles in hemostasis
    Seongcheol Kim
    Department of Biological Sciences, University of North Texas, 1510 Chestnut, Denton TX 76203, USA
    Blood Cells Mol Dis 48:188-96. 2012
  6. pmc Zebrafish von Willebrand factor
    Maira Carrillo
    Department of Biological Sciences, University of North Texas, Denton, TX 76203, USA
    Blood Cells Mol Dis 45:326-33. 2010
  7. doi request reprint Laser-induced thrombosis in zebrafish
    Pudur Jagadeeswaran
    Department of Biological Sciences, University of North Texas, Denton, Texas, USA
    Methods Cell Biol 101:197-203. 2011
  8. pmc Vivo-Morpholino knockdown of alphaIIb: A novel approach to inhibit thrombocyte function in adult zebrafish
    Seongcheol Kim
    Department of Biological Sciences, University of North Texas, Denton, 76203, USA
    Blood Cells Mol Dis 44:169-74. 2010
  9. doi request reprint Separation of young and mature thrombocytes by a novel immuno-selection method
    Vrinda Kulkarni
    Department of Biological Sciences, University of North Texas, 1510 Chestnut Denton, TX 76203, USA
    Blood Cells Mol Dis 48:183-7. 2012
  10. ncbi request reprint Role of hepsin in factor VII activation in zebrafish
    Gauri Khandekar
    Department of Biological Sciences, University of North Texas, Denton, TX, USA
    Blood Cells Mol Dis 52:76-81. 2014

Research Grants

  1. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2005
  2. Fish as Genetic Models for Aging
    Pudur Jagadeeswaran; Fiscal Year: 2002
  3. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2002
  4. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2006
  5. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2007
  6. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2005
  7. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2000
  8. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2003
  9. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2001

Collaborators

  • S Kim
  • Shuo Lin
  • PAMELA RAYMOND
  • KEITH CHI CHENG
  • Shannon Fisher
  • Marnie E Halpern
  • Stephan C F Neuhauss
  • Gauri Khandekar
  • Vrinda Kulkarni
  • Michael Gregory
  • Kenneth Day
  • Maira Carrillo
  • Ravikumar Hanumanthaiah
  • David A Buchner
  • Ronja Bahadori
  • Bijoy Thattaliyath
  • Rebecca L Lamason
  • Michael Herrera
  • Michael G Prouty
  • Lala Zafreen
  • Surendra Kumar Rajpurohit
  • Andrew W Hanosh
  • Brant M Weinstein
  • Beth McGee
  • Susan E Lyons
  • David Ginsburg
  • Nathan D Lawson
  • Makoto Kamei
  • Fengyun Su
  • Jennifer S Yamaoka
  • Daniel Goldman
  • Julio D Amigo
  • Linda K Barthel
  • Jordan A Shavit
  • Yuri V Makhankov
  • Oliver Rinner
  • Prashanth Rao
  • Helia Berrit Schonthaler
  • Oliver Biehlmaier
  • Matthew Cykowski
  • Paul M McKeigue
  • Jessica L Moore
  • Mark D Shriver
  • Wei Zhao
  • Andrew C Wong
  • Soniya Sinha
  • Victor A Canfield
  • Nancy J Mangini
  • Michele C Aros
  • Jason R Mest
  • Esteban J Parra
  • David J Grunwald
  • Izabela Makalowska
  • Manzoor Ali P K Mohideen
  • Xianyun Mao
  • Vanessa R Humphreville
  • Heather L Norton
  • David O'Donnell
  • Gang Ning
  • Rick Kittles
  • Michael J Jurynec
  • Jasper E Humbert
  • Naveen Krishnegowda
  • Lucia P Barker
  • Nidia E Correa
  • Karl E Klose

Detail Information

Publications25

  1. ncbi request reprint Zebrafish: from hematology to hydrology
    P Jagadeeswaran
    Department of Biological Sciences, University of North Texas, Denton, TX 76203, USA
    J Thromb Haemost 5:300-4. 2007
    ..Recently, we have discovered that fish secrete proteases, which participate in hemostasis and may have direct relevance in humans. Future work to identify most of the players in thrombus formation is underway...
  2. pmc Zebrafish thrombocytes: functions and origins
    Gauri Khandekar
    Department of Biological Sciences, University of North Texas, Denton, TX 76203 5017, USA
    Adv Hematol 2012:857058. 2012
    ..This paper integrates the information available on zebrafish thrombocyte function and its formation...
  3. pmc Evolution of primary hemostasis in early vertebrates
    Seongcheol Kim
    Department of Biological Sciences, University of North Texas, Denton, Texas, USA
    PLoS ONE 4:e8403. 2009
    ..Thus, this finding provides evidence for the role of trypsins in primary hemostasis in early vertebrates...
  4. pmc Loss of GATA1 and gain of FLI1 expression during thrombocyte maturation
    Pudur Jagadeeswaran
    Department of Biological Sciences, University of North Texas, Denton, 76203, USA
    Blood Cells Mol Dis 44:175-80. 2010
    ....
  5. doi request reprint Role of zebrafish thrombocyte and non-thrombocyte microparticles in hemostasis
    Seongcheol Kim
    Department of Biological Sciences, University of North Texas, 1510 Chestnut, Denton TX 76203, USA
    Blood Cells Mol Dis 48:188-96. 2012
    ..This finding may have applications for understanding the role of platelet microparticles in humans and may have diagnostic applications...
  6. pmc Zebrafish von Willebrand factor
    Maira Carrillo
    Department of Biological Sciences, University of North Texas, Denton, TX 76203, USA
    Blood Cells Mol Dis 45:326-33. 2010
    ..This exon is also conserved in other fishes. In summary, we established that zebrafish vWF has a role similar to that of vWF found in humans, thus, making zebrafish a useful model for studying the cell biology of vWF in vivo...
  7. doi request reprint Laser-induced thrombosis in zebrafish
    Pudur Jagadeeswaran
    Department of Biological Sciences, University of North Texas, Denton, Texas, USA
    Methods Cell Biol 101:197-203. 2011
    ..In this paper, we describe the principle of this method as well as provide the detailed protocol so this could be used as a screening tool to measure hemostasis in any laboratory...
  8. pmc Vivo-Morpholino knockdown of alphaIIb: A novel approach to inhibit thrombocyte function in adult zebrafish
    Seongcheol Kim
    Department of Biological Sciences, University of North Texas, Denton, 76203, USA
    Blood Cells Mol Dis 44:169-74. 2010
    ..This study also provides the first antisense antithrombotic approach to inhibit thrombocyte function in adult zebrafish...
  9. doi request reprint Separation of young and mature thrombocytes by a novel immuno-selection method
    Vrinda Kulkarni
    Department of Biological Sciences, University of North Texas, 1510 Chestnut Denton, TX 76203, USA
    Blood Cells Mol Dis 48:183-7. 2012
    ..Our technique separates and differentiates young and mature thrombocytes from whole blood. This method is specific and is effective with small amounts of blood...
  10. ncbi request reprint Role of hepsin in factor VII activation in zebrafish
    Gauri Khandekar
    Department of Biological Sciences, University of North Texas, Denton, TX, USA
    Blood Cells Mol Dis 52:76-81. 2014
    ..Our results thus indicate that hepsin plays a physiologically important role in factor VII activation and hemostasis in zebrafish. ..
  11. pmc Modular, easy-to-assemble, low-cost zebrafish facility
    Seongcheol Kim
    Department of Biological Sciences, University of North Texas, Denton, Texas 76203, USA
    Zebrafish 6:269-74. 2009
    ..This is easy to maintain and will take only approximately $500 and a half a day to build an 80-tank module. The system described here will be useful to even investigators who are new to zebrafish aquaculture...
  12. pmc pak2a mutations cause cerebral hemorrhage in redhead zebrafish
    David A Buchner
    Howard Hughes Medical Institute and Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA
    Proc Natl Acad Sci U S A 104:13996-4001. 2007
    ..These data provide in vivo evidence for a critical function of Pak2 in vascular integrity and demonstrate a severe disease phenotype resulting from loss of Pak2 function...
  13. ncbi request reprint Laser-induced thrombosis in zebrafish larvae: a novel genetic screening method for thrombosis
    Pudur Jagadeeswaran
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, USA
    Methods Mol Med 129:187-95. 2006
    ..These mutants can be grown, bred, and further evaluated for the genetic etiology of their abnormal hemostatic pathways...
  14. ncbi request reprint The Zebrafish fade out mutant: a novel genetic model for Hermansky-Pudlak syndrome
    Ronja Bahadori
    Swiss Federal Institute of Technology ETH, Department of Biology, and Brain Research Institute, University of Zurich, Zurich, Switzerland
    Invest Ophthalmol Vis Sci 47:4523-31. 2006
    ..To characterize retinal morphology and visual system function in the zebrafish mutant fade out (fad) and to establish the mutant as a lower vertebrate model for Hermansky-Pudlak syndrome (HPS)...
  15. ncbi request reprint Comprehensive analysis of blood coagulation pathways in teleostei: evolution of coagulation factor genes and identification of zebrafish factor VIIi
    Ravikumar Hanumanthaiah
    Department of Cellular and Structural Biology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Blood Cells Mol Dis 29:57-68. 2002
    ....
  16. ncbi request reprint Genetic analysis of hemostasis and thrombosis using vascular occlusion
    Michael Gregory
    Department of Cellular and Structural Biology, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Blood Cells Mol Dis 29:286-95. 2002
    ..Thus, the vascular occlusion assay developed in this report measures in vivo thrombus formation and is a powerful tool for identifying novel genes involved in thrombosis...
  17. ncbi request reprint Zebrafish-Mycobacterium marinum model for mycobacterial pathogenesis
    Michael G Prouty
    Department of Microbiology and Immunology, University of Texas Health Science Center, San Antonio, TX 78229, USA
    FEMS Microbiol Lett 225:177-82. 2003
    ..This model allows the genetics of mycobacterial disease to be studied in both pathogen and host...
  18. ncbi request reprint Radiographic analysis of zebrafish skeletal defects
    Shannon Fisher
    Department of Embryology, Carnegie Institution of Washington, Baltimore, MD 21210, USA
    Dev Biol 264:64-76. 2003
    ..Radiography is a practical screening tool to detect subtle skeletal abnormalities in the adult zebrafish. The identification of chihuahua demonstrates that mutant phenotypes analogous to human skeletal dysplasias will be discovered...
  19. ncbi request reprint Knockdown of prothrombin in zebrafish
    Kenneth Day
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    Blood Cells Mol Dis 32:191-8. 2004
    ..The system developed here should be useful for investigation of the role of thrombin in vertebrate development...
  20. ncbi request reprint Annual fish as a genetic model for aging
    Michael Herrera
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, 78229, USA
    J Gerontol A Biol Sci Med Sci 59:101-7. 2004
    ....
  21. ncbi request reprint Vascular occlusion and thrombosis in zebrafish
    Pudur Jagadeeswaran
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA
    Methods Cell Biol 76:489-500. 2004
  22. ncbi request reprint Zebrafish: a tool to study hemostasis and thrombosis
    Pudur Jagadeeswaran
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA
    Curr Opin Hematol 12:149-52. 2005
    ....
  23. pmc Young thrombocytes initiate the formation of arterial thrombi in zebrafish
    Bijoy Thattaliyath
    Department of Cellular and Structural Biology, The University of Texas Health Science Center, 7703 Floyd Curl Dr, San Antonio, TX 78229, USA
    Blood 106:118-24. 2005
    ..Since arterial thrombus formation is a fundamental hemostatic event, this mechanism may be conserved in mammals and may open new avenues for prevention of arterial thrombosis...
  24. ncbi request reprint SLC24A5, a putative cation exchanger, affects pigmentation in zebrafish and humans
    Rebecca L Lamason
    Jake Gittlen Cancer Research Foundation, Department of Pathology, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA
    Science 310:1782-6. 2005
    ....
  25. ncbi request reprint Selective labeling of zebrafish thrombocytes: quantitation of thrombocyte function and detection during development
    Michael Gregory
    Department of Cellular and Structural Biology, The University of Texas Health Science Center at San Antonio, 78229, USA
    Blood Cells Mol Dis 28:418-27. 2002
    ..These findings will prove helpful in dissecting the functions of thrombocytes in hemostasis and provide further insight into the role of platelets in thrombosis...

Research Grants10

  1. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2005
    ..Such studies should provide insight into the role of platelet microparticles in hemostasis, mechanisms of their production and platelet maturation. ..
  2. Fish as Genetic Models for Aging
    Pudur Jagadeeswaran; Fiscal Year: 2002
    ..These results will also serve as preliminary data for a future NIH R01 grant application focusing on screening of Cynolebias mutants for long life span. ..
  3. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2002
    ..Identification of human homologues will further our understanding of how the coagulation cascade functions in vivo, suggest novel targets for antithrombotic therapy and provide candidate genetic markers for thrombotic disease. ..
  4. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2006
    ..Such studies should provide insight into the role of platelet microparticles in hemostasis, mechanisms of their production and platelet maturation. ..
  5. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2007
    ..Such studies should provide insight into the role of platelet microparticles in hemostasis, mechanisms of their production and platelet maturation. ..
  6. Role of Young Thrombocytes and Their Microparticles
    Pudur Jagadeeswaran; Fiscal Year: 2005
    ..Such studies should provide insight into the role of platelet microparticles in hemostasis, mechanisms of their production and platelet maturation. ..
  7. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2000
    ..Identification of human homologues will further our understanding of how the coagulation cascade functions in vivo, suggest novel targets for antithrombotic therapy and provide candidate genetic markers for thrombotic disease. ..
  8. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2003
    ..Identification of human homologues will further our understanding of how the coagulation cascade functions in vivo, suggest novel targets for antithrombotic therapy and provide candidate genetic markers for thrombotic disease. ..
  9. SATURATION MUTAGENESIS OF ZEBRAFISH COAGULATION PATHWAY
    Pudur Jagadeeswaran; Fiscal Year: 2001
    ..Identification of human homologues will further our understanding of how the coagulation cascade functions in vivo, suggest novel targets for antithrombotic therapy and provide candidate genetic markers for thrombotic disease. ..