Judith A Jaehning

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. pmc The Paf1 complex: platform or player in RNA polymerase II transcription?
    Judith A Jaehning
    Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Biochim Biophys Acta 1799:379-88. 2010
  2. pmc Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II
    Kristen Nordick
    Department of Biochemistry and Molecular Genetics and Molecular Biology Program, University of Colorado School of Medicine, 12801 East 17th Ave, P O Box 6511, Aurora, CO 80045, USA
    Eukaryot Cell 7:1158-67. 2008
  3. pmc Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization
    Stephanie E Porter
    Department of Biochemistry and Molecular Genetics, Molecular Biology Program, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Eukaryot Cell 4:209-20. 2005
  4. ncbi The Paf1 complex has functions independent of actively transcribing RNA polymerase II
    Cherie L Mueller
    Department of Biochemistry and Molecular Genetics, Molecular Biology Program, University of Colorado Health Science Center, B121, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Mol Cell 14:447-56. 2004
  5. ncbi Mitochondrial transcription is regulated via an ATP "sensing" mechanism that couples RNA abundance to respiration
    Elizabeth A Amiott
    Department of Biochemistry and Molecular Genetics and Molecular Biology Program, University of Colorado at Denver and Health Sciences Center, MS 8101, P O Box 6511, Aurora, 80045, USA
    Mol Cell 22:329-38. 2006
  6. ncbi Sensitivity of the yeast mitochondrial RNA polymerase to +1 and +2 initiating nucleotides
    Elizabeth A Amiott
    Department of Biochemistry and Molecular Genetics and the Program in Molecular Biology, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado 80045, USA
    J Biol Chem 281:34982-8. 2006
  7. ncbi Expression and purification of wild type and mutant forms of the yeast mitochondrial core RNA polymerase, Rpo41
    Michio Matsunaga
    Department of Biochemistry and Molecular Genetics, and Molecular Biology Program, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Protein Expr Purif 35:126-30. 2004
  8. pmc Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex
    Cherie L Mueller
    Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Mol Cell Biol 22:1971-80. 2002

Collaborators

  • Elizabeth A Amiott
  • Cherie L Mueller
  • Stephanie E Porter
  • Kristen Nordick
  • Matthew G Hoffman
  • Michio Matsunaga
  • JOAN L BETZ
  • Kristi L Penheiter
  • Sei Heon Jang

Detail Information

Publications8

  1. pmc The Paf1 complex: platform or player in RNA polymerase II transcription?
    Judith A Jaehning
    Department of Biochemistry and Molecular Genetics, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Biochim Biophys Acta 1799:379-88. 2010
    ....
  2. pmc Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II
    Kristen Nordick
    Department of Biochemistry and Molecular Genetics and Molecular Biology Program, University of Colorado School of Medicine, 12801 East 17th Ave, P O Box 6511, Aurora, CO 80045, USA
    Eukaryot Cell 7:1158-67. 2008
    ..The lack of this connection helps to explain the defects in 3'-end formation observed in the absence of Paf1...
  3. pmc Separation of the Saccharomyces cerevisiae Paf1 complex from RNA polymerase II results in changes in its subnuclear localization
    Stephanie E Porter
    Department of Biochemistry and Molecular Genetics, Molecular Biology Program, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Eukaryot Cell 4:209-20. 2005
    ..Instead, we speculate that the change in localization may reflect a link between the Paf1C and newly synthesized mRNAs as they exit the nucleus...
  4. ncbi The Paf1 complex has functions independent of actively transcribing RNA polymerase II
    Cherie L Mueller
    Department of Biochemistry and Molecular Genetics, Molecular Biology Program, University of Colorado Health Science Center, B121, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Mol Cell 14:447-56. 2004
    ..Therefore, the major functions of Paf1 can be independent of actively transcribing Pol II...
  5. ncbi Mitochondrial transcription is regulated via an ATP "sensing" mechanism that couples RNA abundance to respiration
    Elizabeth A Amiott
    Department of Biochemistry and Molecular Genetics and Molecular Biology Program, University of Colorado at Denver and Health Sciences Center, MS 8101, P O Box 6511, Aurora, 80045, USA
    Mol Cell 22:329-38. 2006
    ..We propose that shifting cellular pools of ATP coordinately control nuclear and mitochondrial transcription...
  6. ncbi Sensitivity of the yeast mitochondrial RNA polymerase to +1 and +2 initiating nucleotides
    Elizabeth A Amiott
    Department of Biochemistry and Molecular Genetics and the Program in Molecular Biology, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado 80045, USA
    J Biol Chem 281:34982-8. 2006
    ....
  7. ncbi Expression and purification of wild type and mutant forms of the yeast mitochondrial core RNA polymerase, Rpo41
    Michio Matsunaga
    Department of Biochemistry and Molecular Genetics, and Molecular Biology Program, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Protein Expr Purif 35:126-30. 2004
    ..An additional advantage of the isolation of Rpo41 from bacterial cells is the absence of its associated specificity factor Mtf1. This allows analysis of combinations of mutant forms of both components of the mtRNAP holoenzyme...
  8. pmc Ctr9, Rtf1, and Leo1 are components of the Paf1/RNA polymerase II complex
    Cherie L Mueller
    Department of Biochemistry and Molecular Genetics, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Mol Cell Biol 22:1971-80. 2002
    ..We suggest that lack of Paf1 results in a defective complex and a block in transcription, which is relieved by removal of Leo1 or Rtf1...