Michael A Jacobs

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc Comprehensive transposon mutant library of Pseudomonas aeruginosa
    Michael A Jacobs
    Department of Medicine, University of Washington Genome Center, Box 352145, Seattle, WA 98195 2145, USA
    Proc Natl Acad Sci U S A 100:14339-44. 2003
  2. pmc Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains
    Laurence Rohmer
    Department of Genome Sciences, University of Washington, Campus Box 357710, 1705 NE Pacific Street Seattle, Washington 98195, USA
    Genome Biol 8:R102. 2007
  3. pmc Chloroplast His-to-Asp signal transduction: a potential mechanism for plastid gene regulation in Heterosigma akashiwo (Raphidophyceae)
    Melinda R Duplessis
    Department of Biology, University of Washington, Seattle, WA 98195 5325, USA
    BMC Evol Biol 7:70. 2007
  4. pmc Chloroplast genome sequencing analysis of Heterosigma akashiwo CCMP452 (West Atlantic) and NIES293 (West Pacific) strains
    Rose Ann Cattolico
    Department of Biology, University of Washington, Box 355325, Seattle, WA 98195 5325, USA
    BMC Genomics 9:211. 2008
  5. pmc Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections
    Stephen J Salipante
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    PLoS ONE 8:e65226. 2013
  6. pmc Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients
    Hillary S Hayden
    Genome Center, University of Washington, Seattle, WA 98195, USA
    Genomics 91:530-7. 2008
  7. doi request reprint How to make a defined near-saturation mutant library. Case 1: Pseudomonas aeruginosa PAO1
    Michael A Jacobs
    Department of Medicine, University of Washington Genome Center, Seattle, WA, USA
    Methods Mol Biol 416:133-52. 2008
  8. pmc Genomic analysis of the emergence of 20th century epidemic dysentery
    Laurence Rohmer
    Department of Microbiology, University of Washington, Seattle, WA, USA
    BMC Genomics 15:355. 2014
  9. ncbi request reprint Multiarm high-throughput integration site detection: limitations of LAM-PCR technology and optimization for clonal analysis
    Michael A Harkey
    Department of Transplantation Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Stem Cells Dev 16:381-92. 2007
  10. ncbi request reprint Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells
    Brian C Beard
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Mol Ther 15:1356-65. 2007

Collaborators

Detail Information

Publications11

  1. pmc Comprehensive transposon mutant library of Pseudomonas aeruginosa
    Michael A Jacobs
    Department of Medicine, University of Washington Genome Center, Box 352145, Seattle, WA 98195 2145, USA
    Proc Natl Acad Sci U S A 100:14339-44. 2003
    ..The transposons used to generate the mutant collection have added features that should facilitate downstream studies of gene expression, protein localization, epistasis, and chromosome engineering...
  2. pmc Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains
    Laurence Rohmer
    Department of Genome Sciences, University of Washington, Campus Box 357710, 1705 NE Pacific Street Seattle, Washington 98195, USA
    Genome Biol 8:R102. 2007
    ....
  3. pmc Chloroplast His-to-Asp signal transduction: a potential mechanism for plastid gene regulation in Heterosigma akashiwo (Raphidophyceae)
    Melinda R Duplessis
    Department of Biology, University of Washington, Seattle, WA 98195 5325, USA
    BMC Evol Biol 7:70. 2007
    ..Hara et Chihara [syn. H. carterae (Hulburt) F.J.R. Taylor]. The presence, structure and putative function of this protein pair are discussed in the context of their evolutionary homologues...
  4. pmc Chloroplast genome sequencing analysis of Heterosigma akashiwo CCMP452 (West Atlantic) and NIES293 (West Pacific) strains
    Rose Ann Cattolico
    Department of Biology, University of Washington, Box 355325, Seattle, WA 98195 5325, USA
    BMC Genomics 9:211. 2008
    ..The technique has been used to sequence chloroplast DNA of two Heterosigma akashiwo strains. This raphidophyte has served as a model system for studies of stramenopile chloroplast biogenesis and evolution...
  5. pmc Rapid 16S rRNA next-generation sequencing of polymicrobial clinical samples for diagnosis of complex bacterial infections
    Stephen J Salipante
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    PLoS ONE 8:e65226. 2013
    ..The described method is sufficiently rapid (theoretically compatible with same-day turnaround times) and inexpensive for routine clinical use...
  6. pmc Large-insert genome analysis technology detects structural variation in Pseudomonas aeruginosa clinical strains from cystic fibrosis patients
    Hillary S Hayden
    Genome Center, University of Washington, Seattle, WA 98195, USA
    Genomics 91:530-7. 2008
    ..aeruginosa and validates a technology that complements emerging, short-read sequencing methods that are better suited to characterizing single-nucleotide polymorphisms than structural variation...
  7. doi request reprint How to make a defined near-saturation mutant library. Case 1: Pseudomonas aeruginosa PAO1
    Michael A Jacobs
    Department of Medicine, University of Washington Genome Center, Seattle, WA, USA
    Methods Mol Biol 416:133-52. 2008
    ..It is clear that many avenues of research have been accelerated by this collection and that additional large mutant strain collections will further aid in defining gene function and biological processes in pathogens...
  8. pmc Genomic analysis of the emergence of 20th century epidemic dysentery
    Laurence Rohmer
    Department of Microbiology, University of Washington, Seattle, WA, USA
    BMC Genomics 15:355. 2014
    ..Sd1 is only detected in the context of human infections, and the circumstances under which epidemics emerge and regress remain unknown...
  9. ncbi request reprint Multiarm high-throughput integration site detection: limitations of LAM-PCR technology and optimization for clonal analysis
    Michael A Harkey
    Department of Transplantation Biology, Fred Hutchinson Cancer Research Center, Seattle, WA 98109 1024, USA
    Stem Cells Dev 16:381-92. 2007
    ....
  10. ncbi request reprint Comparison of HIV-derived lentiviral and MLV-based gammaretroviral vector integration sites in primate repopulating cells
    Brian C Beard
    Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Mol Ther 15:1356-65. 2007
    ..These data help define the relative risk of insertional mutagenesis with MLV-, HIV-, and simian immunodeficiency virus (SIV)-based vectors in a highly relevant primate model...
  11. pmc A comprehensive transposon mutant library of Francisella novicida, a bioweapon surrogate
    Larry A Gallagher
    Department of Genome Sciences, University of Washington, Campus Box 355065, 1705 NE Pacific Street, Seattle, WA 98195, USA
    Proc Natl Acad Sci U S A 104:1009-14. 2007
    ..The library provides a resource for virtually complete identification of genes involved in virulence and other nonessential processes...