GERALD JACOBS

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Evolution of vertebrate colour vision
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    Clin Exp Optom 87:206-16. 2004
  2. ncbi request reprint Polymorphic New World monkeys with more than three M/L cone types
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    J Opt Soc Am A Opt Image Sci Vis 22:2072-80. 2005
  3. ncbi request reprint Visual pigments of marine carnivores: pinnipeds, polar bear, and sea otter
    David H Levenson
    Scripps Institution of Oceanography, UCSD, La Jolla, CA, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 192:833-43. 2006
  4. doi request reprint Losses of functional opsin genes, short-wavelength cone photopigments, and color vision--a significant trend in the evolution of mammalian vision
    Gerald H Jacobs
    Department of Psychological and Brain Sciences, University of California, Santa Barbara, California 93106, USA
    Vis Neurosci 30:39-53. 2013
  5. doi request reprint The evolution of vertebrate color vision
    Gerald H Jacobs
    Department of Psychology, University of California, Santa Barbara, California, USA
    Adv Exp Med Biol 739:156-72. 2012
  6. ncbi request reprint ERG measurements of the spectral sensitivity of common chimpanzee (Pan troglodytes)
    G H Jacobs
    Neuroscience Research Institute, Santa Barbara, CA, USA
    Vision Res 36:2587-94. 1996
  7. ncbi request reprint L and M cone proportions in polymorphic New World monkeys
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, California 93106, USA
    Vis Neurosci 23:365-70. 2006
  8. ncbi request reprint Emergence of novel color vision in mice engineered to express a human cone photopigment
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    Science 315:1723-5. 2007
  9. ncbi request reprint Contributions of the mouse UV photopigment to the ERG and to vision
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA
    Doc Ophthalmol 115:137-44. 2007
  10. doi request reprint Primate color vision: a comparative perspective
    Gerald H Jacobs
    Department of Psychology, Neuroscience Research Institute, University of California, Santa Barbara, California 93106, USA
    Vis Neurosci 25:619-33. 2008

Research Grants

  1. WITHIN SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 2002
  2. WITHIN-SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 1992
  3. WITHIN-SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 1980
  4. WITHIN-SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 2007

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Evolution of vertebrate colour vision
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    Clin Exp Optom 87:206-16. 2004
    ....
  2. ncbi request reprint Polymorphic New World monkeys with more than three M/L cone types
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    J Opt Soc Am A Opt Image Sci Vis 22:2072-80. 2005
    ..The peak sensitivity values for these pigments extend across the range from 530 to 562 nm. The result is an enhanced array of potential color vision phenotypes in this species...
  3. ncbi request reprint Visual pigments of marine carnivores: pinnipeds, polar bear, and sea otter
    David H Levenson
    Scripps Institution of Oceanography, UCSD, La Jolla, CA, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 192:833-43. 2006
    ..Rod photoreceptor responses for all three species were as predicted by the genetic data...
  4. doi request reprint Losses of functional opsin genes, short-wavelength cone photopigments, and color vision--a significant trend in the evolution of mammalian vision
    Gerald H Jacobs
    Department of Psychological and Brain Sciences, University of California, Santa Barbara, California 93106, USA
    Vis Neurosci 30:39-53. 2013
    ..Nocturnality thus appears to set the stage for loss of functional SWS1 opsin genes in mammals, but it cannot be the sole circumstance...
  5. doi request reprint The evolution of vertebrate color vision
    Gerald H Jacobs
    Department of Psychology, University of California, Santa Barbara, California, USA
    Adv Exp Med Biol 739:156-72. 2012
    ..In this chapter I review and comment on these advances...
  6. ncbi request reprint ERG measurements of the spectral sensitivity of common chimpanzee (Pan troglodytes)
    G H Jacobs
    Neuroscience Research Institute, Santa Barbara, CA, USA
    Vision Res 36:2587-94. 1996
    ..Curve-fitting analyses suggest that spectral filtering may be lower in the chimpanzee lens than it is in the human lens, and that the L/M cone ratio is lower in the chimpanzee...
  7. ncbi request reprint L and M cone proportions in polymorphic New World monkeys
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, California 93106, USA
    Vis Neurosci 23:365-70. 2006
    ..At the same time, there were significant individual variations in L:M cone proportions. The genesis of this variation and its implications for seeing are discussed...
  8. ncbi request reprint Emergence of novel color vision in mice engineered to express a human cone photopigment
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    Science 315:1723-5. 2007
    ..An inherent plasticity in the mammalian visual system thus permits the emergence of a new dimension of sensory experience based solely on gene-driven changes in receptor organization...
  9. ncbi request reprint Contributions of the mouse UV photopigment to the ERG and to vision
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, Santa Barbara, CA 93106, USA
    Doc Ophthalmol 115:137-44. 2007
    ....
  10. doi request reprint Primate color vision: a comparative perspective
    Gerald H Jacobs
    Department of Psychology, Neuroscience Research Institute, University of California, Santa Barbara, California 93106, USA
    Vis Neurosci 25:619-33. 2008
    ..This work is also yielding valuable insights into the evolution of color vision...
  11. pmc Evolution of colour vision in mammals
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    Philos Trans R Soc Lond B Biol Sci 364:2957-67. 2009
    ..This article concerns the evolution of colour vision among the mammals, viewing that process in the context of relevant biological mechanisms, of variations in mammalian colour vision, and of the utility of colour vision...
  12. pmc Cone pigments in a North American marsupial, the opossum (Didelphis virginiana)
    Gerald H Jacobs
    Department of Psychology, University of California, Santa Barbara, 93106, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 196:379-84. 2010
    ..We found no evidence that such a mechanism contributes to the ERG in this marsupial...
  13. doi request reprint The Verriest Lecture 2009: recent progress in understanding mammalian color vision
    Gerald H Jacobs
    Department of Psychology and Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA
    Ophthalmic Physiol Opt 30:422-34. 2010
    ..Successes in linking opsin genes and photopigments to color vision have been key to the progress made on each of these issues...
  14. ncbi request reprint Influence of cone pigment coexpression on spectral sensitivity and color vision in the mouse
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106 5060, USA
    Vision Res 44:1615-22. 2004
    ..Complete selective segregation of opsins into individual photoreceptors is apparently not a prerequisite for color vision...
  15. ncbi request reprint Diurnality and cone photopigment polymorphism in strepsirrhines: examination of linkage in Lemur catta
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, California 93106, USA
    Am J Phys Anthropol 122:66-72. 2003
    ..In conjunction with earlier results, this implies that cone pigment polymorphism is unlikely to exist in this species and that, accordingly, such variation is not a consistently predictable feature of vision in diurnal strepsirrhines...
  16. ncbi request reprint An animal model for studying cone function in retinal detachment
    Gerald H Jacobs
    Department of Psychology, University of California, Santa Barbara 93106, USA
    Doc Ophthalmol 104:119-32. 2002
    ..Surgical reattachment produced a progressive recovery of cone-based signals. The ground squirrel seems likely to provide a useful animal model for studying the dynamics of cone function in retinal detachment and subsequent events...
  17. ncbi request reprint Opsin gene and photopigment polymorphism in a prosimian primate
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    Vision Res 42:11-8. 2002
    ..The distribution of these pigments among animals predicts the presence of both dichromatic and trichromatic forms of color vision...
  18. ncbi request reprint Cone-based vision of rats for ultraviolet and visible lights
    G H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    J Exp Biol 204:2439-46. 2001
    ..Evidence of dichromatic color vision in the rat was subsequently obtained from tests of wavelength discrimination...
  19. ncbi request reprint Cone pigment variations in four genera of new world monkeys
    Gerald H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    Vision Res 43:227-36. 2003
    ..Across subjects a total of five different M/L cone pigments were inferred with a subset of three of these present in each species...
  20. ncbi request reprint Visual adaptations in a diurnal rodent, Octodon degus
    G H Jacobs
    Neuroscience Research Institute, University of California, Santa Barbara, CA 93106, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 189:347-61. 2003
    ..In behavioral tests degus were shown to be able to make color discriminations between ultraviolet and visible lights...
  21. pmc Photopigments and colour vision in New World monkeys from the family Atelidae
    G H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    Proc Biol Sci 268:695-702. 2001
    ..This feature directly influences the relative numbers of dichromatic and trichromatic monkeys...
  22. pmc Uniformity of colour vision in Old World monkeys
    G H Jacobs
    Neuroscience Research Institute, University of California, Santa Barbara 93106, USA
    Proc Biol Sci 266:2023-8. 1999
    ..Direct comparisons of the spectral sensitivity functions of Old World monkeys suggest there are no significant variations in the spectral positions of the cone pigments underlying the trichromatic colour vision of Old World monkeys...
  23. ncbi request reprint Prospects for trichromatic color vision in male Cebus monkeys
    G H Jacobs
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    Behav Brain Res 101:109-12. 1999
    ..An examination of the literature on Cebus. monkey photopigments and results from a replication of the discrimination experiment conducted with dichromatic human subjects cast doubt on this claim...
  24. ncbi request reprint A perspective on color vision in platyrrhine monkeys
    G H Jacobs
    Neuroscience Research Institute, University of California, Santa Barbara 93106, USA
    Vision Res 38:3307-13. 1998
    ..Examination of color vision, photopigments, and photopigment genes of all of these monkeys have stimulated a renewed interest in understanding the evolution of primate color vision...
  25. ncbi request reprint Photoreceptors and photopigments in a subterranean rodent, the pocket gopher (Thomomys bottae)
    Gary A Williams
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 191:125-34. 2005
    ..Rod densities are lower than those typical for nocturnal mammals...
  26. doi request reprint Absence of functional short-wavelength sensitive cone pigments in hamsters (Mesocricetus)
    Gary A Williams
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:429-39. 2008
    ..Members of this genus belong to a disparate group of mammals that have lost function of their short-wavelength sensitive cone pigments through ancestral opsin gene mutations...
  27. ncbi request reprint Cone pigment polymorphism in New World monkeys: are all pigments created equal?
    Mickey P Rowe
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, 93106, USA
    Vis Neurosci 21:217-22. 2004
    ..In all cases, performance was best for simulated trichromacies including M/L pigments with the largest spectral separation. Thus, the inequality of opsin gene frequency in Callitrichid monkeys may reflect adaptive pressures...
  28. ncbi request reprint Spectral properties and retinal distribution of ferret cones
    Jack B Calderone
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara 93106, USA
    Vis Neurosci 20:11-7. 2003
    ....
  29. pmc Cone-based vision in the aging mouse
    Gary A Williams
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, CA 93106, USA
    Vision Res 47:2037-46. 2007
    ..The age-related decline in Vmax seen in mice is qualitatively similar to that documented for human subjects. It is notable that Vmax, a commonly used index of ERG activity, does not predict behavioral performance in the mouse...
  30. ncbi request reprint Naturalistic color discriminations in polymorphic platyrrhine monkeys: effects of stimulus luminance and duration examined with functional substitution
    Mickey P Rowe
    Neuroscience Research Institute, University of California, Santa Barbara, California, USA
    Vis Neurosci 24:17-23. 2007
    ..There was limited agreement among the predictions made by these models regarding the capabilities of animals with different pigment pairs and none predicted the dependence of discrimination on changes in luminance and stimulus duration...
  31. ncbi request reprint Rod and cone function in coneless mice
    Gary A Williams
    Neuroscience Research Institute and Department of Psychology, University of California, Santa Barbara, 93106, USA
    Vis Neurosci 22:807-16. 2005
    ..Coneless mice are able to make accurate rod-based visual discriminations at light levels well in excess of those required to reach cone threshold in wild-type mice...
  32. ncbi request reprint Early afferent signaling in the outer plexiform layer regulates development of horizontal cell morphology
    Mary A Raven
    Neuroscience Research Institute, University of California, Santa Barbara 93106 5060, USA
    J Comp Neurol 506:745-58. 2008
    ..Together, they suggest a complex cascade of interactions between developing cone pedicles and horizontal cell dendrites involving early spontaneous activity, dendritic attraction, ribbon assembly, and pedicle invagination...
  33. ncbi request reprint Cone photoreceptor recovery after experimental detachment and reattachment: an immunocytochemical, morphological, and electrophysiological study
    Tsutomu Sakai
    Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, CA 93106 5060, USA
    Invest Ophthalmol Vis Sci 44:416-25. 2003
    ..To compare the morphologic and functional recovery of the retina after detachment and reattachment in an animal with a cone-dominant retina, the ground squirrel...
  34. ncbi request reprint Topography of photoreceptors and retinal ganglion cells in the spotted hyena (Crocuta crocuta)
    Jack B Calderone
    Neuroscience Research Institute and Department of Psychology, University of California Santa Barbara, Santa Barbara, CA 93106, USA
    Brain Behav Evol 62:182-92. 2003
    ..Using standard assumptions the maximum spatial resolution of the spotted hyena is calculated to be about 8.4 cycles/degree, a value similar to estimates obtained for other terrestrial carnivores...
  35. ncbi request reprint Mutational changes in S-cone opsin genes common to both nocturnal and cathemeral Aotus monkeys
    David H Levenson
    Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography, La Jolla, San Diego, California, USA
    Am J Primatol 69:757-65. 2007
    ....
  36. pmc Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision
    Philip M Smallwood
    Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 100:11706-11. 2003
    ....

Research Grants24

  1. WITHIN SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 2002
    ..Preliminary results suggest that there may be polymorphic variants leading to protanopia. ..
  2. WITHIN-SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 1992
    ..Preliminary results suggest that there may be polymorphic variants leading to protanopia...
  3. WITHIN-SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 1980
    ..Finally, a behavioral experiment on squirrel monkeys is proposed that involves an attempt to gain information as to the significance for normal behavior of this within-species variation in visual capacity...
  4. WITHIN-SPECIES VARIATIONS IN VISUAL CAPACITY
    GERALD JACOBS; Fiscal Year: 2007
    ....