Daniel J Jackson
Affiliation: University of Wisconsin
- Rhinovirus illnesses during infancy predict subsequent childhood wheezingRobert F Lemanske
Department of Pediatrics, University of Wisconsin, Madison, WI 53792 9988, USA edu
J Allergy Clin Immunol 116:571-7. 2005..The contribution of viral respiratory infections during infancy to the development of subsequent wheezing and/or allergic diseases in early childhood is not established...
- Viral infections, cytokine dysregulation and the origins of childhood asthma and allergic diseasesSamuel L Friedlander
Department of Medicine, Wisconsin State Laboratory of Hygiene, University of Wisconsin, Madison, WI, USA
Pediatr Infect Dis J 24:S170-6, discussion S174-5. 2005..The origins of asthma and allergic disease begin in early life for many individuals. It is vital to understand the factors and/or events leading to their development...
- Wheezing rhinovirus illnesses in early life predict asthma development in high-risk childrenDaniel J Jackson
Department of Pediatrics, University of Wisconsin Madison, Madison, WI, USA
Am J Respir Crit Care Med 178:667-72. 2008..Virus-induced wheezing episodes in infancy often precede the development of asthma. Whether infections with specific viral pathogens confer differential future asthma risk is incompletely understood...
- Evidence for a causal relationship between allergic sensitization and rhinovirus wheezing in early lifeDaniel J Jackson
University of Wisconsin, Madison, 53792, USA
Am J Respir Crit Care Med 185:281-5. 2012..Aeroallergen sensitization and virus-induced wheezing are risk factors for asthma development during early childhood, but the temporal developmental sequence between them is incompletely understood...
- Fractional exhaled nitric oxide measurements are most closely associated with allergic sensitization in school-age childrenDaniel J Jackson
Department of Pediatrics, University of Wisconsin Madison, Madison, Wis, USA
J Allergy Clin Immunol 124:949-53. 2009..Factors affecting fractional exhaled nitric oxide (FeNO) in early childhood are incompletely understood...
- The role of rhinovirus infections in the development of early childhood asthmaDaniel J Jackson
University of Wisconsin School of Medicine and Public Health, Department of Pediatrics, Madison, Wisconsin 53792, USA
Curr Opin Allergy Clin Immunol 10:133-8. 2010..To discuss the role of human rhinoviruses (HRVs) in early childhood wheezing illnesses and how HRVs contribute to the development of childhood asthma...
- The role of respiratory virus infections in childhood asthma inceptionDaniel J Jackson
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Madison, WI 53792, USA
Immunol Allergy Clin North Am 30:513-22, vi. 2010..In this article, the authors review the impact of virus infections during early life, focusing primarily on RSV and HRV, and their potential roles in asthma inception...
- Childhood asthma clusters and response to therapy in clinical trialsTimothy S Chang
Department of Biostatistics and Medical Informatics, University of Wisconsin School of Medicine and Public Health, Madison, Wis
J Allergy Clin Immunol 133:363-369.e3. 2014..Childhood asthma clusters, or subclasses, have been developed by computational methods without evaluation of clinical utility...
- Protection from asthma in a high-risk birth cohort by attenuated P2X(7) functionDavid M Manthei
Department of Medicine, University of Wisconsin Madison, Madison, WI 53792, USA
J Allergy Clin Immunol 130:496-502. 2012..The purinergic receptor P2X(7) can enhance airway leukocyte recruitment to the airways, and P2X(7) knockout mice display a reduced asthma-like phenotype...
- Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthmaTheresa W Guilbert
Department of Pediatrics, University of Wisconsin Madison, Madison, WI 53716, USA
J Allergy Clin Immunol 128:532-8.e1-10. 2011..Preschool rhinovirus (RV) wheezing illnesses predict an increased risk of childhood asthma; however, it is not clear how specific viral illnesses in early life relate to lung function later on in childhood...
- Do oral corticosteroids reduce the severity of acute lower respiratory tract illnesses in preschool children with recurrent wheezing?Avraham Beigelman
Department of Pediatrics, Washington University and St Louis Children s Hospital, St Louis, MO 63110, USA
J Allergy Clin Immunol 131:1518-25. 2013..Oral corticosteroids (OCSs) are recommended for severe wheezing episodes in children. However, limited evidence supports this intervention in preschool children with outpatient wheezing illnesses...
- Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic childrenSandy R Durrani
Department of Medicine, University of Wisconsin Madison School of Medicine and Public Health, Madison, WI 53792 9988, USA
J Allergy Clin Immunol 130:489-95. 2012..Children with allergic asthma have more frequent and severe human rhinovirus (HRV)-induced wheezing and asthma exacerbations through unclear mechanisms...
- Effect of exogenous interferons on rhinovirus replication and airway inflammatory responsesTess M Becker
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
Ann Allergy Asthma Immunol 111:397-401. 2013..Furthermore, the effects of exogenous IFN could be type specific in part because of the cellular distribution of type 1 and type 2 IFN receptors...
- Pulmonary 3He magnetic resonance imaging of childhood asthmaRobert V Cadman
Department of Medical Physics, School of Medicine and Public Health, University of Wisconsin Madison, Madison, Wis 53705, USA
J Allergy Clin Immunol 131:369-76.e1-5. 2013..Measurements of regional lung ventilation and microstructure in subjects with childhood asthma could advance our understanding of disease mechanisms...
- Daily diaries vs retrospective questionnaires to assess asthma control and therapeutic responses in asthma clinical trials: is participant burden worth the effort?Adesua Y Okupa
University of Wisconsin School of Medicine and Public Health, Madison, WI 53792, USA
Chest 143:993-9. 2013..There is also concern that retrospective symptom questionnaires may be subject to poor recall and may be insensitive...
- Approaches to stepping up and stepping down care in asthmatic patientsAlex Thomas
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wis 53792, USA
J Allergy Clin Immunol 128:915-24; quiz 925-6. 2011....
- Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroidsRobert F Lemanske
University of Wisconsin School of Medicine and Public Health, Madison, USA
N Engl J Med 362:975-85. 2010..For children who have uncontrolled asthma despite the use of low-dose inhaled corticosteroids (ICS), evidence to guide step-up therapy is lacking...
- Infections and their role in childhood asthma inceptionAmy O Thomas
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA
Pediatr Allergy Immunol 25:122-8. 2014..This article serves to review these relationships among infections, host factors, and asthma inception in childhood. ..
- Asthma: NHLBI Workshop on the Primary Prevention of Chronic Lung DiseasesDaniel J Jackson
1 Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
Ann Am Thorac Soc 11:S139-45. 2014....