Research Topics
Genomes and Genes | Alexander C JacksonSummaryAffiliation: University of California Country: USA Publications
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Publications
The expanding social network of ionotropic glutamate receptors: TARPs and other transmembrane auxiliary subunitsAlexander C Jackson
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143, USA
Neuron 70:178-99. 2011..Here we review pivotal developments in our understanding of the role of TARPs in AMPA receptor trafficking and gating, and provide an overview of how newly discovered transmembrane proteins expand our view of iGluR function in the CNS...
Stargazin (TARP gamma-2) is required for compartment-specific AMPA receptor trafficking and synaptic plasticity in cerebellar stellate cellsAlexander C Jackson
Department of Cellular and Molecular Pharmacology and Physiology, University of California, San Francisco, California 94143, USA
J Neurosci 31:3939-52. 2011..Together, these data suggest that stargazin regulates compartment-specific AMPAR trafficking, as well as activity-dependent plasticity in synaptic AMPAR rectification at cerebellar PF-SC synapses...
Subunit composition of synaptic AMPA receptors revealed by a single-cell genetic approachWei Lu
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143, USA
Neuron 62:254-68. 2009..This study provides a functional quantification of the subunit composition of AMPARs in the CNS and suggests novel roles for AMPAR subunits in receptor trafficking...
Probing TARP modulation of AMPA receptor conductance with polyamine toxinsAlexander C Jackson
Department of Cellular and Molecular Pharmacology, University of California, San Francisco, California 94143, USA
J Neurosci 31:7511-20. 2011....
Trpv1 reporter mice reveal highly restricted brain distribution and functional expression in arteriolar smooth muscle cellsDaniel J Cavanaugh
Department of Anatomy, University of San Francisco, San Francisco, California 94158, USA
J Neurosci 31:5067-77. 2011..Here, capsaicin increases calcium uptake and induces vasoconstriction, an effect that likely counteracts the vasodilation produced by activation of neuronal TRPV1...
