Joachim Ix

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Fibroblast growth factor 23, bone mineral density, and risk of hip fracture among older adults: the cardiovascular health study
    Anna Jovanovich
    Division of Renal Diseases and Hypertension, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 98:3323-31. 2013
  2. pmc Fractional excretion of phosphorus modifies the association between fibroblast growth factor-23 and outcomes
    Julie R Dominguez
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, CA, USA
    J Am Soc Nephrol 24:647-54. 2013
  3. pmc Test characteristics of the ankle-brachial index and ankle-brachial difference for medial arterial calcification on X-ray in type 1 diabetes
    Joachim H Ix
    Nephrology Section, Veterans Affairs San Diego Healthcare System, University of California, San Diego, San Diego, Calif 92161, USA
    J Vasc Surg 56:721-7. 2012
  4. doi request reprint Fetuin-A is inversely associated with coronary artery calcification in community-living persons: the Multi-Ethnic Study of Atherosclerosis
    Joachim H Ix
    Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    Clin Chem 58:887-95. 2012
  5. pmc Association of fetuin-a with incident diabetes mellitus in community-living older adults: the cardiovascular health study
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego VA Healthcare System, San Diego, CA 92161, USA
    Circulation 125:2316-22. 2012
  6. pmc Influence of urine creatinine on the relationship between the albumin-to-creatinine ratio and cardiovascular events
    Caitlin E Carter
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, USA
    Clin J Am Soc Nephrol 7:595-603. 2012
  7. pmc Interdialytic creatinine change versus predialysis creatinine as indicators of nutritional status in maintenance hemodialysis
    Carl P Walther
    Department of Medicine, University of California San Diego, San Diego, CA, USA
    Nephrol Dial Transplant 27:771-6. 2012
  8. pmc Association of osteocalcin and abdominal aortic calcification in older women: the study of osteoporotic fractures
    Benjamin D Parker
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, San Diego, CA 92093, USA
    Calcif Tissue Int 86:185-91. 2010
  9. doi request reprint Epidemiology and diagnosis of peripheral arterial disease in patients with chronic kidney disease
    Joachim H Ix
    Department of Medicine, Division of Nephrology and Hypertension, University of California San Diego, San Diego, CA 92161, USA
    Adv Chronic Kidney Dis 15:378-83. 2008
  10. pmc Fetuin-A and BMD in older persons: the Health Aging and Body Composition (Health ABC) study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, California, USA
    J Bone Miner Res 24:514-21. 2009

Detail Information

Publications56

  1. pmc Fibroblast growth factor 23, bone mineral density, and risk of hip fracture among older adults: the cardiovascular health study
    Anna Jovanovich
    Division of Renal Diseases and Hypertension, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 98:3323-31. 2013
    ..Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that also inhibits calcitriol synthesis...
  2. pmc Fractional excretion of phosphorus modifies the association between fibroblast growth factor-23 and outcomes
    Julie R Dominguez
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, CA, USA
    J Am Soc Nephrol 24:647-54. 2013
    ..In summary, associations of FGF23 with mortality and CVD events are stronger in persons with lower FePi independent of PTH and kidney function. In such individuals, the renal tubular response to FGF23 may be suboptimal...
  3. pmc Test characteristics of the ankle-brachial index and ankle-brachial difference for medial arterial calcification on X-ray in type 1 diabetes
    Joachim H Ix
    Nephrology Section, Veterans Affairs San Diego Healthcare System, University of California, San Diego, San Diego, Calif 92161, USA
    J Vasc Surg 56:721-7. 2012
    ..We hypothesized that an ABI >1.30 and ABD >75 mm Hg would have high specificity but low sensitivity for MAC on X-ray imaging...
  4. doi request reprint Fetuin-A is inversely associated with coronary artery calcification in community-living persons: the Multi-Ethnic Study of Atherosclerosis
    Joachim H Ix
    Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, CA 92161, USA
    Clin Chem 58:887-95. 2012
    ..Fetuin-A is a hepatic secretory protein that inhibits arterial calcification in vitro. The association of fetuin-A with coronary arterial calcification (CAC) in the general population is uncertain...
  5. pmc Association of fetuin-a with incident diabetes mellitus in community-living older adults: the cardiovascular health study
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego VA Healthcare System, San Diego, CA 92161, USA
    Circulation 125:2316-22. 2012
    ..We sought to confirm the association of fetuin-A with incident diabetes mellitus in older persons and to determine whether the association differs by age, sex, and race and among persons with cardiovascular disease (CVD)...
  6. pmc Influence of urine creatinine on the relationship between the albumin-to-creatinine ratio and cardiovascular events
    Caitlin E Carter
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, USA
    Clin J Am Soc Nephrol 7:595-603. 2012
    ....
  7. pmc Interdialytic creatinine change versus predialysis creatinine as indicators of nutritional status in maintenance hemodialysis
    Carl P Walther
    Department of Medicine, University of California San Diego, San Diego, CA, USA
    Nephrol Dial Transplant 27:771-6. 2012
    ..Predialysis creatinine levels are associated with mortality risk but may be influenced by both muscle mass and dialysis dose. This might be overcome by examining the rate of rise in creatinine between dialysis sessions...
  8. pmc Association of osteocalcin and abdominal aortic calcification in older women: the study of osteoporotic fractures
    Benjamin D Parker
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, San Diego, CA 92093, USA
    Calcif Tissue Int 86:185-91. 2010
    ..87). In conclusion, among community-living older women, serum OC is not associated with AAC. These findings suggest that serum OC levels may more closely reflect bone formation than vascular calcification in humans...
  9. doi request reprint Epidemiology and diagnosis of peripheral arterial disease in patients with chronic kidney disease
    Joachim H Ix
    Department of Medicine, Division of Nephrology and Hypertension, University of California San Diego, San Diego, CA 92161, USA
    Adv Chronic Kidney Dis 15:378-83. 2008
    ..To that end, we review the epidemiology and diagnosis of atherosclerotic PAD and medical arterial calcification in patients with CKD...
  10. pmc Fetuin-A and BMD in older persons: the Health Aging and Body Composition (Health ABC) study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, California, USA
    J Bone Miner Res 24:514-21. 2009
    ..Future studies should evaluate whether fetuin-A may refine fracture risk assessment in older women...
  11. pmc Urinary creatinine excretion rate and mortality in persons with coronary artery disease: the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, and VA San Diego Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    Circulation 121:1295-303. 2010
    ..In persons with coronary artery disease, low body mass index is associated with greater mortality; however, it is uncertain whether low muscle mass is a risk factor for mortality in this setting...
  12. pmc Serum phosphorus concentrations and arterial stiffness among individuals with normal kidney function to moderate kidney disease in MESA
    Joachim H Ix
    Department of Medicine, Division of Nephrology and Hypertension, University of California San Diego, San Diego, CA 92161, USA
    Clin J Am Soc Nephrol 4:609-15. 2009
    ..Higher phosphorus levels are associated with cardiovascular disease (CVD) events and mortality. Whether vascular stiffness may be responsible is unknown...
  13. pmc Association of chronic kidney disease with the spectrum of ankle brachial index the CHS (Cardiovascular Health Study)
    Joachim H Ix
    Department of Medicine, University of California San Diego, USA
    J Am Coll Cardiol 54:1176-84. 2009
    ..This study sought to determine the association of chronic kidney disease (CKD) with high ankle brachial index (ABI) measurement and to compare its strength with that of CKD with a low ABI...
  14. pmc Fetuin-A and change in body composition in older persons
    Joachim H Ix
    Division of Nephrology, Department of Medicine, and Division of Preventive Medicine, University of California San Diego, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    J Clin Endocrinol Metab 94:4492-8. 2009
    ..Whether higher fetuin-A concentrations are associated with accumulation of adiposity over time is unknown...
  15. ncbi request reprint Fetuin-A is not associated with mortality in chronic kidney disease
    J H Ix
    Division of Nephrology and Hypertension, University of California San Diego, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    Kidney Int 72:1394-9. 2007
    ..Our study shows that serum fetuin-A levels are not related to all-cause or cardiovascular mortality among persons with predominantly non-diabetic stage 3 or 4 CKD...
  16. pmc A high ankle brachial index is associated with greater left ventricular mass MESA (Multi-Ethnic Study of Atherosclerosis)
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, California 92161, USA
    J Am Coll Cardiol 55:342-9. 2010
    ..This study sought to determine the association of high ankle brachial index (ABI) measurements with left ventricular (LV) mass, and to compare its strength with that of low ABI with LV mass...
  17. pmc Fetuin-A and incident diabetes mellitus in older persons
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego, and San Diego Veterans Affairs Healthcare System, 3350 La Jolla Village Dr, Mail Code 111 H, San Diego, CA 92161, USA
    JAMA 300:182-8. 2008
    ..In prior cross-sectional studies in humans, higher fetuin-A levels were associated with insulin resistance. However, the longitudinal association of fetuin-A with incident type 2 diabetes mellitus is unknown...
  18. pmc Association of mild to moderate kidney dysfunction and coronary calcification
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, and San Diego VA Healthcare System, 3350 La Jolla Village Drive, Mail Code 111 H, San Diego, CA 92161, USA
    J Am Soc Nephrol 19:579-85. 2008
    ..These results suggest that a higher burden of CAC is unlikely to explain the association between mild to moderate kidney dysfunction and cardiovascular mortality...
  19. pmc Equations to estimate creatinine excretion rate: the CKD epidemiology collaboration
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, and San Diego VA Healthcare System, 3350 La Jolla Village Drive, Mail Code 111 H, San Diego, CA 92161, USA
    Clin J Am Soc Nephrol 6:184-91. 2011
    ..Creatinine excretion rate (CER) indicates timed urine collection accuracy. Although equations to estimate CER exist, their bias and precision are untested and none simultaneously include age, sex, race, and weight...
  20. pmc Fibroblast growth factor-23 and early decrements in kidney function: the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, CA, USA
    Nephrol Dial Transplant 25:993-7. 2010
    ..The threshold of CKD or albuminuria at which FGF-23 begins to change is unknown...
  21. pmc The associations of fetuin-A with subclinical cardiovascular disease in community-dwelling persons: the Rancho Bernardo Study
    Joachim H Ix
    Nephrology Section, Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA
    J Am Coll Cardiol 58:2372-9. 2011
    ..The aim of this study was to determine the association of fetuin-A with subclinical cardiovascular disease (CVD) in community-living individuals...
  22. pmc Association of body mass index with peripheral arterial disease in older adults: the Cardiovascular Health Study
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California, San Diego and San Diego VA HealthCare System, San Diego, CA 92161, USA
    Am J Epidemiol 174:1036-43. 2011
    ..00, 1.76) among never smokers in good health. Greater BMI is associated with PAD in older persons who remain healthy and have never smoked. Normal weight maintenance may decrease PAD incidence and associated comorbidity in older age...
  23. pmc Relation of sex and estrogen therapy to serum fibroblast growth factor 23, serum phosphorus, and urine phosphorus: the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego, San Diego, CA 92161, USA
    Am J Kidney Dis 58:737-45. 2011
    ..Fibroblast growth factor 23 (FGF-23) is a hormone originating from bone that regulates urine phosphorus excretion. Whether sex or estrogen therapy is associated with different FGF-23 levels is unknown...
  24. pmc Cystatin C identifies chronic kidney disease patients at higher risk for complications
    Carmen A Peralta
    San Francisco Veterans Affairs Medical Center, San Francisco, California, USA
    J Am Soc Nephrol 22:147-55. 2011
    ..Cystatin C may have a role in identifying persons with CKD who have the highest risk for complications...
  25. doi request reprint Genetic ancestry and lower extremity peripheral artery disease in the Multi-Ethnic Study of Atherosclerosis
    Matthew A Allison
    Department of Family and Preventive Medicine, University of California San Diego, La Jolla, CA 92093 0965, USA
    Vasc Med 15:351-9. 2010
    ....
  26. pmc Fetuin-A and kidney function in persons with coronary artery disease--data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Nephrol Dial Transplant 21:2144-51. 2006
    ..Whether fetuin-A concentrations are also lower in the setting of mild-to-moderate chronic kidney disease (CKD) is unknown...
  27. pmc Incidence and progression of coronary calcification in chronic kidney disease: the Multi-Ethnic Study of Atherosclerosis
    Bryan R Kestenbaum
    Division of Nephrology, Department of Medicine, Harborview Medical Center, Kidney Research Institute, University of Washington, Seattle, Washington 98104 2499, USA
    Kidney Int 76:991-8. 2009
    ..Our study shows that coronary artery calcification is common in people with stage 3 disease, progresses rapidly, and may contribute to cardiovascular risk...
  28. pmc Racial and ethnic differences in kidney function decline among persons without chronic kidney disease
    Carmen A Peralta
    Department of Medicine, University of California San Francisco, San Francisco, California 94121, USA
    J Am Soc Nephrol 22:1327-34. 2011
    ..Traditional risk factors do not explain these differences fully, highlighting the need to explore these disparities...
  29. pmc Association of fetuin-A with mitral annular calcification and aortic stenosis among persons with coronary heart disease: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    Circulation 115:2533-9. 2007
    ..Lower serum fetuin-A concentrations are associated with valvular calcification in persons with end-stage renal disease. Whether fetuin-A is associated with valvular calcification in other patient populations is unknown...
  30. pmc Obesity and change in estimated GFR among older adults
    Ian H De Boer
    Division of Nephrology, University of Washington, Seattle, WA 98195, USA
    Am J Kidney Dis 54:1043-51. 2009
    ..Obesity assessed in midlife has been associated with chronic kidney disease...
  31. pmc Kidney function and systolic blood pressure new insights from cystatin C: data from the Heart and Soul Study
    Carmen A Peralta
    General Internal Medicine Section, San Francisco Veterans Affairs Medical Center, and Department of Medicine, University of California, San Francisco, San Francisco, California 94124, USA
    Am J Hypertens 19:939-46. 2006
    ..Whether kidney function in the normal range is associated with systolic BP (SBP), diastolic BP (DBP), and pulse pressure is unclear...
  32. pmc Relation of kidney function and albuminuria with atrial fibrillation (from the Heart and Soul Study)
    David D McManus
    Section of Cardiac Electrophysiology, Division of Cardiology, Department of Medicine, University of Massachusetts, Worcester, Massachusetts, USA
    Am J Cardiol 104:1551-5. 2009
    ..36, 95% CI 1.45 to 13.05) or eGFR(Cr) (OR 4.61, 95% CI 1.56 to 13.66). In conclusion, among outpatients with coronary artery disease, lower eGFR(cys) and higher ACR were associated with prevalent AF, independent of each other...
  33. pmc Association of cystatin C and estimated GFR with inflammatory biomarkers: the Heart and Soul Study
    David Singh
    Department of Medicine, University of California, San Francisco, CA 94121, USA
    Nephrol Dial Transplant 22:1087-92. 2007
    ..In this study, we compared the relative strengths of association of cystatin C and estimated glomerular filtration rate (eGFR) with inflammatory biomarkers...
  34. pmc Racial differences in the association of pentraxin-3 with kidney dysfunction: the Multi-Ethnic Study of Atherosclerosis
    Ruth Dubin
    Department of Medicine, Division of Nephrology, University of California San Francisco, San Francisco, CA, USA
    Nephrol Dial Transplant 26:1903-8. 2011
    ..Pentraxin-3 (PTX3), an inflammatory marker thought to be related to vascular inflammation, is elevated in advanced chronic kidney disease (CKD). Whether PTX3 is associated with mild to moderate kidney dysfunction is unknown...
  35. doi request reprint Novel cardiovascular risk factors do not completely explain the higher prevalence of peripheral arterial disease among African Americans. The San Diego Population Study
    Joachim H Ix
    Department of Medicine, University of California, San Diego, San Diego, California 92161, USA
    J Am Coll Cardiol 51:2347-54. 2008
    ..This study was designed to determine whether novel cardiovascular disease (CVD) risk factors explain the high prevalence of peripheral arterial disease (PAD) among African Americans...
  36. pmc Association of cystatin C with mortality, cardiovascular events, and incident heart failure among persons with coronary heart disease: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California at San Francisco, San Francisco, CA 94143 0532, USA
    Circulation 115:173-9. 2007
    ..Cystatin C is a novel and sensitive endogenous marker of kidney function. Whether cystatin C concentrations are associated with adverse events among ambulatory persons with CHD is unknown...
  37. pmc The ankle-brachial index and incident cardiovascular events in the MESA (Multi-Ethnic Study of Atherosclerosis)
    Michael H Criqui
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, California 92093 0607, USA
    J Am Coll Cardiol 56:1506-12. 2010
    ..The purpose of this study was to examine the association of both a low and a high ankle-brachial index (ABI) with incident cardiovascular events in a multiethnic cohort...
  38. pmc Risk factor differences for aortic versus coronary calcified atherosclerosis: the multiethnic study of atherosclerosis
    Michael H Criqui
    Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA 92093 0607, USA
    Arterioscler Thromb Vasc Biol 30:2289-96. 2010
    ..The goal of this study was to compare and contrast coronary artery calcium (CAC) with abdominal aortic calcium (AAC) in terms of their associations with traditional and novel cardiovascular disease (CVD) risk factors...
  39. pmc N-acetylcysteine for the prevention of contrast-induced nephropathy. A systematic review and meta-analysis
    Raymond Liu
    Department of Medicine, University of California, San Francisco, CA, USA
    J Gen Intern Med 20:193-200. 2005
    ..We conducted a systematic review to determine whether administering N-acetylcysteine around the time of contrast administration reduces the risk of contrast-induced nephropathy...
  40. pmc Associations of estradiol and testosterone with serum phosphorus in older men: the Osteoporotic Fractures in Men study
    Jerry Meng
    Division of Nephrology, Department of Medicine, University of California San Diego, San Diego, California, USA
    Kidney Int 78:415-22. 2010
    ..The mechanism responsible for the association of testosterone with serum phosphorus remains to be determined...
  41. ncbi request reprint Association of chronic kidney disease with clinical outcomes after coronary revascularization: the Arterial Revascularization Therapies Study (ARTS)
    Joachim H Ix
    Department of Medicine, University of California, San Francisco, Calif, USA
    Am Heart J 149:512-9. 2005
    ..In the Arterial Revascularization Therapies Study (ARTS), we compared long-term clinical outcomes after CABG or PCI with multivessel stenting in patients with CKD...
  42. pmc Serum phosphorus levels and the spectrum of ankle-brachial index in older men: the Osteoporotic Fractures in Men (MrOS) study
    Jerry Meng
    Division of Nephrology, Department of Medicine, School of Medicine, University of California, San Diego, La Jolla, California, USA
    Am J Epidemiol 171:909-16. 2010
    ..These associations may explain the link between serum phosphorus levels and CVD events...
  43. pmc The associations of fibroblast growth factor 23 and uncarboxylated matrix Gla protein with mortality in coronary artery disease: the Heart and Soul Study
    Benjamin D Parker
    Division of Nephrologyand Hypertension, Department of Medicine, University of California San Diego, CA 92161, USA
    Ann Intern Med 152:640-8. 2010
    ..Whether circulating levels of each are associated with cardiovascular disease (CVD) events or mortality in populations without end-stage renal disease is unknown...
  44. ncbi request reprint Serum methylmalonic acid and holotranscobalamin-II as markers for vitamin B12 deficiency in end-stage renal disease patients
    Navaid Iqbal
    VA Medical Center San Diego, San Diego, CA 92161, USA
    Ann Clin Lab Sci 43:243-9. 2013
    ..We investigated the role renal failure has on MMA and holoTC concentrations and evaluated using MMA and/or holoTC to identify B12 deficient patients...
  45. pmc Association of kidney function and uncarboxylated matrix Gla protein: data from the Heart and Soul Study
    Benjamin D Parker
    Division of Nephrology and Hypertension, Department of Medicine, Veterans Affairs San Diego Healthcare System, San Diego, CA, USA
    Nephrol Dial Transplant 24:2095-101. 2009
    ..Whether mild to moderate decrements in kidney function are associated with lower serum ucMGP is unknown...
  46. ncbi request reprint Kidney function and aortic valve and mitral annular calcification in the Multi-Ethnic Study of Atherosclerosis (MESA)
    Joachim H Ix
    Department of Medicine, University of California, San Francisco, CA 94143 0532, USA
    Am J Kidney Dis 50:412-20. 2007
    ..Whether less severe kidney dysfunction is associated with AVC and MAC is uncertain...
  47. pmc Cystatin C, left ventricular hypertrophy, and diastolic dysfunction: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, Box 0532, HSE 672, University of California, San Francisco, San Francisco, CA 94143 0532, USA
    J Card Fail 12:601-7. 2006
    ..We evaluate whether cystatin C is associated with left ventricular hypertrophy, diastolic dysfunction, and systolic dysfunction among 818 outpatients with coronary artery disease who were free of clinical heart failure...
  48. pmc Association between human fetuin-A and the metabolic syndrome: data from the Heart and Soul Study
    Joachim H Ix
    Division of Nephrology, Department of Medicine, University of California, San Francisco, CA 94143 0532, USA
    Circulation 113:1760-7. 2006
    ..We evaluated the association between human serum fetuin-A and the metabolic syndrome (MetS) in a cohort of persons with coronary artery disease...
  49. ncbi request reprint Theophylline for the prevention of radiocontrast nephropathy: a meta-analysis
    Joachim H Ix
    Division of Nephrology, Department of Medicine Research, University of California San Francisco, San Francisco, California, USA
    Nephrol Dial Transplant 19:2747-53. 2004
    ..We conducted a meta-analysis of published randomized controlled trials to determine if the pre-procedural administration of theophylline or aminophylline prevents radiocontrast-induced declines in kidney function...
  50. pmc The association of uncarboxylated matrix Gla protein with mitral annular calcification differs by diabetes status: The Heart and Soul study
    Benjamin D Parker
    Department of Medicine, Division of Nephrology, University of California, San Diego, United States
    Atherosclerosis 210:320-5. 2010
    ..Matrix Gla protein (MGP) is an inhibitor of vascular calcification and lower levels of its precursor - uncarboxylated MGP (ucMGP) - are associated with vascular calcification in pilot studies...
  51. doi request reprint Mechanisms linking obesity, chronic kidney disease, and fatty liver disease: the roles of fetuin-A, adiponectin, and AMPK
    Joachim H Ix
    Division of Nephrology and Hypertension, Department of Medicine, University of California San Diego Veterans Affairs San Diego Healthcare System, CA 92093 0711, USA
    J Am Soc Nephrol 21:406-12. 2010
    ..Regulation of these early upstream pathways may provide new therapeutic targets for these increasingly common sequelae of obesity...
  52. pmc Association between renal insufficiency and inducible ischemia in patients with coronary artery disease: the heart and soul study
    Joachim H Ix
    Department of Medicine, University of California, San Francisco, San Francisco, California 94121, USA
    J Am Soc Nephrol 14:3233-8. 2003
    ..The greater severity of atherosclerotic disease observed in patients with CRI may in part explain the association of CRI with increased cardiovascular risk among individuals with CAD...
  53. ncbi request reprint Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis
    Brent W Kinder
    Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, OH, USA
    Chest 133:226-32. 2008
    ..We hypothesized that baseline BAL fluid cell count differential (ie, elevated levels of neutrophils and eosinophils, or reduced levels of lymphocytes) would predict higher mortality among persons with IPF...
  54. pmc Association of cystatin C with poor exercise capacity and heart rate recovery: data from the heart and soul study
    David McManus
    Cardiology Division, University of Massachusetts, Worcester, MA, USA
    Am J Kidney Dis 49:365-72. 2007
    ..We hypothesized that serum cystatin C concentration would have a stronger more linear association with cardiovascular functional status than creatinine-based measures in outpatients with established coronary heart disease (CHD)...
  55. pmc Biomarkers to predict recurrent cardiovascular disease: the Heart and Soul Study
    Michael G Shlipak
    Section of General Internal Medicine, San Francisco VA Medical Center, San Francisco, Calif, USA
    Am J Med 121:50-7. 2008
    ..The study purpose was to evaluate the ability of 6 biomarkers to improve the prediction of cardiovascular events among persons with established coronary artery disease...
  56. ncbi request reprint Utility of cystatin C measurement--precision or secretion?
    Joachim H Ix
    Nephrol Dial Transplant 21:3614. 2006

Research Grants2

  1. Fetuin-A and Incident Cardiovascular Disease, Fracture, and Diabetes
    Joachim Ix; Fiscal Year: 2009
    ..The results of this epidemiologic study will provide novel insights into their pathogenesis and may ultimately identify novel therapeutic targets for their prevention or treatment. ..
  2. Fetuin-A and Incident Cardiovascular Disease, Fracture, and Diabetes
    Joachim H Ix; Fiscal Year: 2010
    ..The results of this epidemiologic study will provide novel insights into their pathogenesis and may ultimately identify novel therapeutic targets for their prevention or treatment. ..