A Itoh

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Diminished calcium homeostasis and increased susceptibility to excitotoxicity of JS 3/16 progenitor cells after differentiation to oligodendroglia
    T Itoh
    Neurology Research, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Glia 31:165-80. 2000
  2. ncbi AMPA glutamate receptor-mediated calcium signaling is transiently enhanced during development of oligodendrocytes
    Takayuki Itoh
    The Children s Hospital of Philadelphia, Pennsylvania, USA
    J Neurochem 81:390-402. 2002
  3. ncbi Bcl-2-related protein family gene expression during oligodendroglial differentiation
    Takayuki Itoh
    Neurology Research, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Neurochem 85:1500-12. 2003
  4. ncbi AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+
    T Itoh
    Division of Neurology, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    J Neurochem 71:112-24. 1998
  5. ncbi Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells
    F N Karanu
    Developmental Stem Cell Biology, The John P. Robarts Research Institute, London, ON, Canada
    Blood 97:1960-7. 2001
  6. ncbi Characterization of the sppA gene coding for protease IV, a signal peptide peptidase of Escherichia coli
    T Suzuki
    J Bacteriol 169:2523-8. 1987
  7. ncbi Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors
    A Itoh
    Section of Biomolecular Medicine, Boston University School of Medicine, MA 02118, USA
    Cell Mol Biol Res 41:147-54. 1995
  8. ncbi Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system
    A Itoh
    Life Science Fundamental Research Laboratory, Asahi Chemical Industry Co, Ltd, 2 1 Samejima, Fuji City, Shizuoka 416 8501, Japan
    Brain Res Mol Brain Res 62:175-86. 1998
  9. ncbi Molecular cloning of a divinyl ether synthase. Identification as a CYP74 cytochrome P-450
    A Itoh
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824 1312, USA
    J Biol Chem 276:3620-7. 2001

Collaborators

Detail Information

Publications9

  1. ncbi Diminished calcium homeostasis and increased susceptibility to excitotoxicity of JS 3/16 progenitor cells after differentiation to oligodendroglia
    T Itoh
    Neurology Research, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    Glia 31:165-80. 2000
    ..The JS 3/16 line provides a valuable system for analysis of intracellular Ca(2+) homeostasis and AMPA-GluR-mediated excitotoxicity in the oligodendroglial lineage...
  2. ncbi AMPA glutamate receptor-mediated calcium signaling is transiently enhanced during development of oligodendrocytes
    Takayuki Itoh
    The Children s Hospital of Philadelphia, Pennsylvania, USA
    J Neurochem 81:390-402. 2002
    ..susceptibility to excitotoxicity of cells at these stages of oligodendroglial differentiation, and is likely to be important to these cells in the trans-synaptic Ca2+-signaling from glutamatergic neurons, which occurs in hippocampus..
  3. ncbi Bcl-2-related protein family gene expression during oligodendroglial differentiation
    Takayuki Itoh
    Neurology Research, The Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA
    J Neurochem 85:1500-12. 2003
    ..These results provide basic information to guide further studies on the roles for Bcl-2-related family proteins in OLC death...
  4. ncbi AMPA receptor-mediated excitotoxicity in human NT2-N neurons results from loss of intracellular Ca2+ homeostasis following marked elevation of intracellular Na+
    T Itoh
    Division of Neurology, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
    J Neurochem 71:112-24. 1998
    ..Our results serve to emphasize the central role of neuronal Na+ loading in AMPA-GluR-mediated excitotoxicity in human neurons...
  5. ncbi Human homologues of Delta-1 and Delta-4 function as mitogenic regulators of primitive human hematopoietic cells
    F N Karanu
    Developmental Stem Cell Biology, The John P. Robarts Research Institute, London, ON, Canada
    Blood 97:1960-7. 2001
    ..This study provides the first evidence for a role of Delta ligands as a mitogenic regulator of primitive hematopoietic cells in the human. (Blood. 2001;97:1960-1967)..
  6. ncbi Characterization of the sppA gene coding for protease IV, a signal peptide peptidase of Escherichia coli
    T Suzuki
    J Bacteriol 169:2523-8. 1987
    ....
  7. ncbi Structural characterization and specificity of expression of E2F-5: a new member of the E2F family of transcription factors
    A Itoh
    Section of Biomolecular Medicine, Boston University School of Medicine, MA 02118, USA
    Cell Mol Biol Res 41:147-54. 1995
    ..The structural divergence between the two branches of the E2F family may thus reflect participation in different regulatory networks...
  8. ncbi Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system
    A Itoh
    Life Science Fundamental Research Laboratory, Asahi Chemical Industry Co, Ltd, 2 1 Samejima, Fuji City, Shizuoka 416 8501, Japan
    Brain Res Mol Brain Res 62:175-86. 1998
    ....
  9. ncbi Molecular cloning of a divinyl ether synthase. Identification as a CYP74 cytochrome P-450
    A Itoh
    Department of Energy Plant Research Laboratory, Michigan State University, East Lansing, Michigan 48824 1312, USA
    J Biol Chem 276:3620-7. 2001
    ..These results indicate that developmental expression of the divinyl ether synthase gene is an important determinant of the tissue specific synthesis of divinyl ether oxylipins...