Eijun Itakura

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi RT in situ PCR detection of MART-1 and TRP-2 mRNA in formalin-fixed, paraffin-embedded tissues of melanoma and nevi
    Eijun Itakura
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Mod Pathol 21:326-33. 2008
  2. ncbi IL-10 expression by primary tumor cells correlates with melanoma progression from radial to vertical growth phase and development of metastatic competence
    Eijun Itakura
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Mod Pathol 24:801-9. 2011
  3. ncbi "Stealth" melanoma cells in histology-negative sentinel lymph nodes
    Eijun Itakura
    Department of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Surg Pathol 35:1657-65. 2011
  4. ncbi Update on lymphatic mapping and sentinel node biopsy in the management of patients with melanocytic tumours
    Alistair J Cochran
    Department of Pathology, David Geffen School of Medicine at UCLA, the Jonsson Comprehensive Cancer Center, Los Angeles, California, USA
    Pathology 36:478-84. 2004
  5. ncbi Optimized assessment of sentinel lymph nodes for metastatic melanoma: implications for regional surgery and overall treatment planning
    Alistair J Cochran
    Departments of Pathology and Laboratory Medicine and Surgery, University of California, Los Angeles School of Medicine, Los Angeles, California, USA
    Ann Surg Oncol 11:156S-61S. 2004
  6. ncbi Detection of multiple melanoma-associated markers in melanoma cell lines by RT in situ PCR
    Jing Guo
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Exp Mol Pathol 74:140-7. 2003
  7. ncbi Accurate evaluation of nodal tissues for the presence of tumor is central to the sentinel node approach
    Alistair J Cochran
    Department of Pathology and Laboratory Medicine and Surgery, David Geffen School of Medicine at UCLA and the Jonsson Comprehensive Cancer Center, Los Angeles, California, USA
    Cancer Treat Res 127:207-20. 2005
  8. ncbi Clinically relevant information from sentinel lymph node biopsies of melanoma patients
    Duan Ren Wen
    Department of Pathology and Laboratory Medicine and Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    J Surg Oncol 104:369-78. 2011
  9. ncbi Tumour-induced immune modulation of sentinel lymph nodes
    Alistair J Cochran
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at the University of California at Los Angeles, California 90095, USA
    Nat Rev Immunol 6:659-70. 2006

Collaborators

Detail Information

Publications9

  1. ncbi RT in situ PCR detection of MART-1 and TRP-2 mRNA in formalin-fixed, paraffin-embedded tissues of melanoma and nevi
    Eijun Itakura
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Mod Pathol 21:326-33. 2008
    ..We conclude that the RT in situ PCR technique can be successfully applied to FFPE tissue to determine the cellular sources of gene expression observed by conventional PCR approaches...
  2. ncbi IL-10 expression by primary tumor cells correlates with melanoma progression from radial to vertical growth phase and development of metastatic competence
    Eijun Itakura
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Mod Pathol 24:801-9. 2011
    ..Alterations of immunity by IL-10 derived from melanoma cells and melanoma-associated macrophages and lymphocytes potentially facilitate evolution of the primary melanoma and render regional lymph nodes susceptible to metastases...
  3. ncbi "Stealth" melanoma cells in histology-negative sentinel lymph nodes
    Eijun Itakura
    Department of Pathology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA
    Am J Surg Pathol 35:1657-65. 2011
    ..These findings should be taken into account when interpreting and applying the results of RT-PCR analysis of nodal (and other) tissues...
  4. ncbi Update on lymphatic mapping and sentinel node biopsy in the management of patients with melanocytic tumours
    Alistair J Cochran
    Department of Pathology, David Geffen School of Medicine at UCLA, the Jonsson Comprehensive Cancer Center, Los Angeles, California, USA
    Pathology 36:478-84. 2004
    ..To communicate best practices for sentinel lymph node evaluation and assessment of prognosis for patients with melanoma...
  5. ncbi Optimized assessment of sentinel lymph nodes for metastatic melanoma: implications for regional surgery and overall treatment planning
    Alistair J Cochran
    Departments of Pathology and Laboratory Medicine and Surgery, University of California, Los Angeles School of Medicine, Los Angeles, California, USA
    Ann Surg Oncol 11:156S-61S. 2004
    ..The most robust of these predictors is relative tumor area, and this may be used as the basis of practical predictive algorithms...
  6. ncbi Detection of multiple melanoma-associated markers in melanoma cell lines by RT in situ PCR
    Jing Guo
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA
    Exp Mol Pathol 74:140-7. 2003
    ..We have attempted to optimize this interesting approach and have applied it to the detection of relevant melanoma markers in tissue culture lines...
  7. ncbi Accurate evaluation of nodal tissues for the presence of tumor is central to the sentinel node approach
    Alistair J Cochran
    Department of Pathology and Laboratory Medicine and Surgery, David Geffen School of Medicine at UCLA and the Jonsson Comprehensive Cancer Center, Los Angeles, California, USA
    Cancer Treat Res 127:207-20. 2005
  8. ncbi Clinically relevant information from sentinel lymph node biopsies of melanoma patients
    Duan Ren Wen
    Department of Pathology and Laboratory Medicine and Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
    J Surg Oncol 104:369-78. 2011
    ..Number of tumor-positive SNs and the amount and location of tumor in SNs correlate with tumor spread to non-sentinel nodes, subsequent recurrences and melanoma death, permitting patient assignment to a risk category...
  9. ncbi Tumour-induced immune modulation of sentinel lymph nodes
    Alistair J Cochran
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at the University of California at Los Angeles, California 90095, USA
    Nat Rev Immunol 6:659-70. 2006
    ..Immune modulation of the lymph nodes can be reversed by granulocyte/macrophage colony-stimulating factor (GM-CSF), a finding that has implications for the future therapy of lymph-node metastases...