James R Ison

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Deficits in responding to brief noise offsets in Kcna1 -/- mice reveal a contribution of this gene to precise temporal processing seen previously only for stimulus onsets
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY 14627, USA
    J Assoc Res Otolaryngol 13:351-8. 2012
  2. ncbi request reprint Pre- but not post-menopausal female CBA/CaJ mice show less prepulse inhibition than male mice of the same age
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY 14627, USA
    Behav Brain Res 185:76-81. 2007
  3. ncbi request reprint The behavioral response of mice to gaps in noise depends on its spectral components and its bandwidth
    James R Ison
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, New York 14627, USA
    J Acoust Soc Am 117:3944-51. 2005
  4. pmc Age-related hearing loss in C57BL/6J mice has both frequency-specific and non-frequency-specific components that produce a hyperacusis-like exaggeration of the acoustic startle reflex
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, Meliora Hall, Rochester, NY 14627, USA
    J Assoc Res Otolaryngol 8:539-50. 2007
  5. ncbi request reprint A diminished rate of "physiological decay" at noise offset contributes to age-related changes in temporal acuity in the CBA mouse model of presbycusis
    James R Ison
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, New York 14627, USA
    J Acoust Soc Am 114:522-8. 2003
  6. pmc Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices
    Marie Eve Tremblay
    Department of Neurobiology and Anatomy and Center for Visual Science, University of Rochester, Rochester, New York 14642, USA
    Glia 60:541-58. 2012
  7. pmc Low-frequency tone pips elicit exaggerated startle reflexes in C57BL/6J mice with hearing loss
    James R Ison
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, NY 14627, USA
    J Assoc Res Otolaryngol 4:495-504. 2003
  8. ncbi request reprint Impaired gap encoding in aged mouse inferior colliculus at moderate but not high stimulus levels
    Paul D Allen
    Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY 14627, USA
    Hear Res 186:17-29. 2003
  9. pmc Kv1.1 channel subunits are not necessary for high temporal acuity in behavioral and electrophysiological gap detection
    Paul D Allen
    Department of Otolaryngology, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Hear Res 246:52-8. 2008
  10. ncbi request reprint Humans detect gaps in broadband noise according to effective gap duration without additional cues from abrupt envelope changes
    Paul D Allen
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, New York 14627, USA
    J Acoust Soc Am 112:2967-74. 2002

Collaborators

Detail Information

Publications19

  1. pmc Deficits in responding to brief noise offsets in Kcna1 -/- mice reveal a contribution of this gene to precise temporal processing seen previously only for stimulus onsets
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY 14627, USA
    J Assoc Res Otolaryngol 13:351-8. 2012
    ..1 contributes to the perception of animal vocalizations and human speech...
  2. ncbi request reprint Pre- but not post-menopausal female CBA/CaJ mice show less prepulse inhibition than male mice of the same age
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY 14627, USA
    Behav Brain Res 185:76-81. 2007
    ..The negative findings previously reported in the mouse can be attributed to the small effect size and to procedural differences, including stimulus conditions, and the different strains and ages of mice...
  3. ncbi request reprint The behavioral response of mice to gaps in noise depends on its spectral components and its bandwidth
    James R Ison
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, New York 14627, USA
    J Acoust Soc Am 117:3944-51. 2005
    ..These effects are similar to those obtained in humans, and reveal a special contribution of wide band, high-frequency stimulation to temporal acuity...
  4. pmc Age-related hearing loss in C57BL/6J mice has both frequency-specific and non-frequency-specific components that produce a hyperacusis-like exaggeration of the acoustic startle reflex
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, Meliora Hall, Rochester, NY 14627, USA
    J Assoc Res Otolaryngol 8:539-50. 2007
    ....
  5. ncbi request reprint A diminished rate of "physiological decay" at noise offset contributes to age-related changes in temporal acuity in the CBA mouse model of presbycusis
    James R Ison
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, New York 14627, USA
    J Acoust Soc Am 114:522-8. 2003
    ..These data indicate that temporal acuity as measured by this gap detection method is limited in very old mice by their reduced ability to follow the abrupt change in noise level at the beginning of the gap...
  6. pmc Effects of aging and sensory loss on glial cells in mouse visual and auditory cortices
    Marie Eve Tremblay
    Department of Neurobiology and Anatomy and Center for Visual Science, University of Rochester, Rochester, New York 14642, USA
    Glia 60:541-58. 2012
    ....
  7. pmc Low-frequency tone pips elicit exaggerated startle reflexes in C57BL/6J mice with hearing loss
    James R Ison
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, NY 14627, USA
    J Assoc Res Otolaryngol 4:495-504. 2003
    ....
  8. ncbi request reprint Impaired gap encoding in aged mouse inferior colliculus at moderate but not high stimulus levels
    Paul D Allen
    Department of Brain and Cognitive Sciences, University of Rochester, Rochester, NY 14627, USA
    Hear Res 186:17-29. 2003
    ..These results demonstrate that age-related changes in temporal acuity may interact with stimulus level, and suggest that adequate amplification may be critically important for maintaining temporal acuity with advancing age...
  9. pmc Kv1.1 channel subunits are not necessary for high temporal acuity in behavioral and electrophysiological gap detection
    Paul D Allen
    Department of Otolaryngology, University of Rochester, School of Medicine and Dentistry, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Hear Res 246:52-8. 2008
    ..These data suggest that the neural pathways encoding behaviorally relevant, rapid auditory temporal fluctuations are not limited by the absence of Kv1.1 expression...
  10. ncbi request reprint Humans detect gaps in broadband noise according to effective gap duration without additional cues from abrupt envelope changes
    Paul D Allen
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, New York 14627, USA
    J Acoust Soc Am 112:2967-74. 2002
    ..These findings suggest that human listeners do not make use of abrupt onset or offset information to enhance gap detection, but seem to rely on the effective sound level reduction associated with the gap for detection...
  11. pmc Kcna1 gene deletion lowers the behavioral sensitivity of mice to small changes in sound location and increases asynchronous brainstem auditory evoked potentials but does not affect hearing thresholds
    Paul D Allen
    Department of Neurobiology and Anatomy, University of Rochester Medical Center, Rochester, New York 14642, USA
    J Neurosci 32:2538-43. 2012
    ....
  12. pmc Sensitivity of the mouse to changes in azimuthal sound location: angular separation, spectral composition, and sound level
    Paul D Allen
    Department of Neurobiology and Anatomy, University of Rochester Medical Center, Rochester, NY 14642, USA
    Behav Neurosci 124:265-77. 2010
    ..These experiments extend the prior findings on sound localization in mice, and the dependence of PPI on ISI adds a reaction time-like dimension to this behavioral analysis...
  13. ncbi request reprint Excision of visual cortex does not affect the facilitatory and inhibitory effects of a light flash prepulse on the acoustic startle reflex in the rat
    G Peter Bowen
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, NY 14627, USA
    Behav Brain Res 168:114-9. 2006
    ....
  14. ncbi request reprint Behavioral and neural measures of auditory temporal acuity in aging humans and mice
    Kathy Barsz
    University of Rochester Medical Center, NY 14642, USA
    Neurobiol Aging 23:565-78. 2002
    ..Age-related changes in temporal acuity appear comparable in humans and mice. The data suggest a common deficit in neural mechanisms...
  15. ncbi request reprint The attention filter for tones in noise has the same shape and effective bandwidth in the elderly as it has in young listeners
    James R Ison
    J Acoust Soc Am 112:238-46. 2002
    ..Confidence intervals (95%) showed that the elderly ERB could be at most only about 20% larger than that of younger listeners...
  16. ncbi request reprint Auditory cortex lesions in the rat impair both temporal acuity and noise increment thresholds, revealing a common neural substrate
    G Peter Bowen
    Department of Brain and Cognitive Sciences, Meliora Hall, University of Rochester, Rochester, NY 14627, USA
    Cereb Cortex 13:815-22. 2003
    ..The data indicate that the auditory cortex is critically important for temporal acuity in hearing, and suggest that its contribution to gap detection is to enhance the salience of noise increments at the end of the gap...
  17. ncbi request reprint Acoustic startle in maltreated children
    Rafael Klorman
    Department of Clinical and Social Sciences in Psychology, University of Rochester, Rochester, New York 14620 0266, USA
    J Abnorm Child Psychol 31:359-70. 2003
    ..Results for girls were inconsistent: younger maltreated girls had smaller startle amplitude and slower onset latency than controls, whereas older maltreated girls exhibited the opposite pattern...
  18. ncbi request reprint The relative detectability for mice of gaps having different ramp durations at their onset and offset boundaries
    James R Ison
    Department of Brain and Cognitive Sciences, University of Rochester, New York 14627, USA
    J Acoust Soc Am 112:740-7. 2002
    ..These effects are specific to gaps: inhibition for fixed (70-dB SPL) or varied level pulses (30 to 60 dB) was unaffected by varying the ramped edges (experiments 3 and 4, n = 9)...
  19. ncbi request reprint Concurrent measurement of the detectability of tone bursts and their effect on the excitability of the human blink reflex using a probe-signal method
    Geoffrey R Hammond
    School of Psychology, The University of Western Australia, Crawley, Australia
    Hear Res 202:28-34. 2005
    ..This finding is consistent with the view that stimuli whose frequency falls outside an attentional band are excluded at the auditory periphery...