Akira Ishiguro

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Essential roles of Bdp1, a subunit of RNA polymerase III initiation factor TFIIIB, in transcription and tRNA processing
    Akira Ishiguro
    Division of Biology and Center for Molecular Genetics, University of California, San Diego, La Jolla, California 92093 0634, USA
    Mol Cell Biol 22:3264-75. 2002
  2. ncbi request reprint A gene-specific effect of an internal deletion in the Bdp1 subunit of the RNA polymerase III transcription initiation factor TFIIIB
    Akira Ishiguro
    Division of Biological Sciences and Center for Molecular Genetics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0634, USA
    FEBS Lett 548:33-6. 2003
  3. ncbi request reprint The fission yeast RPA51 is a functional homolog of the budding yeast A49 subunit of RNA polymerase I and required for maximizing transcription of ribosomal DNA
    Kaori Nakagawa
    Department of Molecular Biology, Saitama Medical School, Iruma gun, Saitama, Japan
    Genes Genet Syst 78:199-209. 2003
  4. ncbi request reprint Dorz1, a novel gene expressed in differentiating cerebellar granule neurons, is down-regulated in Zic1-deficient mouse
    Jun Hoshino
    Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute BSI, 2 1 Hirosawa, Wako, Saitama 351 0918, Japan
    Brain Res Mol Brain Res 120:57-64. 2003
  5. ncbi request reprint Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family
    Akira Ishiguro
    Laboratory for Comparative Neurogenesis, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    Biochem Biophys Res Commun 324:302-7. 2004
  6. ncbi request reprint ZIC2-dependent transcriptional regulation is mediated by DNA-dependent protein kinase, poly(ADP-ribose) polymerase, and RNA helicase A
    Akira Ishiguro
    Laboratory for Comparative Neurogenesis, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    J Biol Chem 282:9983-95. 2007
  7. ncbi request reprint Functional role of Zic2 phosphorylation in transcriptional regulation
    Akira Ishiguro
    Laboratory for Comparative Neurogenesis, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    FEBS Lett 582:154-8. 2008
  8. doi request reprint CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA
    Kumiko Sakai-Kato
    Research Institute of Pharmaceutical Sciences, Musashino University, 1 1 20 Shinmachi, Nishitokyo shi, Tokyo, 202 8585, Japan
    Biochim Biophys Acta 1784:1011-9. 2008

Collaborators

Detail Information

Publications8

  1. pmc Essential roles of Bdp1, a subunit of RNA polymerase III initiation factor TFIIIB, in transcription and tRNA processing
    Akira Ishiguro
    Division of Biology and Center for Molecular Genetics, University of California, San Diego, La Jolla, California 92093 0634, USA
    Mol Cell Biol 22:3264-75. 2002
    ..Physical interaction of RNase P with Bdp1 was demonstrated by coimmunoprecipitation and pull-down assays...
  2. ncbi request reprint A gene-specific effect of an internal deletion in the Bdp1 subunit of the RNA polymerase III transcription initiation factor TFIIIB
    Akira Ishiguro
    Division of Biological Sciences and Center for Molecular Genetics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093 0634, USA
    FEBS Lett 548:33-6. 2003
    ..It is shown that TFIIIC-dependent assembly of TFIIIB on the RPR1 promoter is specifically sensitive to this Bdp1 deletion, leading to gene-specifically defective single-round and multiple-round transcription...
  3. ncbi request reprint The fission yeast RPA51 is a functional homolog of the budding yeast A49 subunit of RNA polymerase I and required for maximizing transcription of ribosomal DNA
    Kaori Nakagawa
    Department of Molecular Biology, Saitama Medical School, Iruma gun, Saitama, Japan
    Genes Genet Syst 78:199-209. 2003
    ..We also found that RPA51 associates significantly with Pol I in the stationary phase, suggesting that Pol I inactivation in the stationary phase of yeast does not result from the RPA51 dissociation...
  4. ncbi request reprint Dorz1, a novel gene expressed in differentiating cerebellar granule neurons, is down-regulated in Zic1-deficient mouse
    Jun Hoshino
    Laboratory for Developmental Neurobiology, RIKEN Brain Science Institute BSI, 2 1 Hirosawa, Wako, Saitama 351 0918, Japan
    Brain Res Mol Brain Res 120:57-64. 2003
    ..In addition, Dorz1 expression was up-regulated in cultured cells overexpressing Zic1. These results suggest that Dorz1 expression is positively regulated by Zic1 during cerebellar development...
  5. ncbi request reprint Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family
    Akira Ishiguro
    Laboratory for Comparative Neurogenesis, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    Biochem Biophys Res Commun 324:302-7. 2004
    ..The difference may be attributable to the dissimilarity of the N-terminal region between the Zic1/Zic2/Zic3 and Zic4/Zic5 proteins, since the binding of the Zic1/Zic2/Zic3 proteins to I-mfa occurs through their N-terminal regions...
  6. ncbi request reprint ZIC2-dependent transcriptional regulation is mediated by DNA-dependent protein kinase, poly(ADP-ribose) polymerase, and RNA helicase A
    Akira Ishiguro
    Laboratory for Comparative Neurogenesis, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    J Biol Chem 282:9983-95. 2007
    ..Phosphorylation-dependent transformation of Zic2-containing molecular complexes may occur in transcriptional regulation...
  7. ncbi request reprint Functional role of Zic2 phosphorylation in transcriptional regulation
    Akira Ishiguro
    Laboratory for Comparative Neurogenesis, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    FEBS Lett 582:154-8. 2008
    ..These data indicate that Zic2S200 is a target for phosphorylation by DNA-dependent protein kinase, regulating Zic2-mediated transcriptional activation...
  8. doi request reprint CD spectra show the relational style between Zic-, Gli-, Glis-zinc finger protein and DNA
    Kumiko Sakai-Kato
    Research Institute of Pharmaceutical Sciences, Musashino University, 1 1 20 Shinmachi, Nishitokyo shi, Tokyo, 202 8585, Japan
    Biochim Biophys Acta 1784:1011-9. 2008
    ..These results suggest that the alpha-helix structure is important for DNA binding and profoundly related to functional and structural diversity among the three families...