Research Topics
| R S IrwinSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
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Detail Information
Publications
Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelinesRichard S Irwin
University of Massachusetts Medical School, Room S6-842, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 129:1S-23S. 2006
Patient-focused care: using the right toolsRichard S Irwin
Pulmonary, Allergy and Critical Care Medicine Division, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 130:73S-82S. 2006....
Side effects with inhaled corticosteroids: the physician's perceptionRichard S Irwin
Pulmonary, Allergy and Critical Care Medicine Division, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 130:41S-53S. 2006..The introduction of new agents with potentially improved safety profiles may reassure physicians and patients as to the relative benefits of ICS therapy in asthma...
Assessing cough severity and efficacy of therapy in clinical research: ACCP evidence-based clinical practice guidelinesRichard S Irwin
University of Massachusetts Medical School, Room S6 842, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 129:232S-237S. 2006..To review the literature on identifying cough and to make evidence-based recommendations for assessing the efficacy of cough-modifying agents in clinical research...
Habit cough, tic cough, and psychogenic cough in adult and pediatric populations: ACCP evidence-based clinical practice guidelinesRichard S Irwin
University of Massachusetts Medical School, Room S6 842, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 129:174S-179S. 2006..To review the literature on habit, tic, and psychogenic cough, and to make evidence-based recommendations regarding diagnosis and treatment...
Introduction to the diagnosis and management of cough: ACCP evidence-based clinical practice guidelinesRichard S Irwin
University of Massachusetts Medical School, Room S6-842, 55 Lake Ave North, Worcester, MA 01655-0330, USA
Chest 129:25S-27S. 2006
Sore throat, dysphagia, stiffness in back of neck, and dyspnea following tricyclic antidepressant overdoseRichard S Irwin
University of Massachusetts Medical School, Pulmonary, Allergy and Critical Care, Worcester, 0165-0330, USA
Chest 124:1533-4. 2003
Chronic cough due to gastroesophageal reflux disease: ACCP evidence-based clinical practice guidelinesRichard S Irwin
University of Massachusetts Medical School, Room S6 842, 55 Lake Ave North, Worcester, MA 01655 0330, USA
Chest 129:80S-94S. 2006..To critically review and summarize the literature on cough and gastroesophageal reflux disease (GERD), and to make evidence-based recommendations regarding the diagnosis and treatment of chronic cough due to GERD...
The critical care professional societies address the critical care crisis in the United StatesRichard S Irwin
Pulmonary, Allergy, and Critical Care Medicine Division, University of Massachusetts Medical School, Worcester, MA, USA
Chest 125:1512-3. 2004
Complications of cough: ACCP evidence-based clinical practice guidelinesRichard S Irwin
University of Massachusetts Medical School, Room S6 842, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 129:54S-58S. 2006..To review the spectrum and frequency of complications associated with coughing...
Interpreting the histopathology of chronic cough: a prospective, controlled, comparative studyRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Chest 130:362-70. 2006..Trauma from chronic coughing produces airway inflammation similar to diseases causing cough...
Quality of life in coughersRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
Pulm Pharmacol Ther 15:283-6. 2002....
The role of conflict of interest in reporting of scientific informationRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Chest 136:253-9. 2009....
The persistently troublesome coughRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Am J Respir Crit Care Med 165:1469-74. 2002
Chronic cough due to gastroesophageal reflux disease: failure to resolve despite total/near-total elimination of esophageal acidRichard S Irwin
Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Chest 121:1132-40. 2002..While medical therapy may fail to improve cough due to gastroesophageal reflux disease (GERD), it is not known if inadequate esophageal acid suppression is responsible...
Unexplained cough in the adultRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Otolaryngol Clin North Am 43:167-80, xi-xii. 2010....
Patient-focused care: the 2003 American College of Chest Physicians Convocation SpeechRichard S Irwin
Pulmonary, Allergy, and Critical Care Medicine Division, UMass Memorial Medical Center, Worcester, MA 01655, USA
Chest 125:1910-2. 2004
Symptom research on chronic cough: a historical perspectiveR S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Ann Intern Med 134:809-14. 2001..to the diagnosis and treatment of chronic cough: empirical therapeutic trials or laboratory testing-directed therapeutic trials? How often is environmental air pollution, unrelated to allergies or smoking, responsible for chronic cough?..
Chronic cough. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapyR S Irwin
Department of Medicine, University of Massachusetts Medical School, Worcester 01655
Am Rev Respir Dis 141:640-7. 1990..Laboratory testing was particularly useful in ruling out suspected possibilities. We conclude that the anatomic diagnostic protocol is still valid and that it has well-defined strengths and limitations...
Gender differences in health-related quality of life in patients complaining of chronic coughCynthia T French
Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Chest 125:482-8. 2004....
The clinical value of pharmacologic bronchoprovocation challengeR S Irwin
University of Massachusetts Medical School, Worcester
Med Clin North Am 74:767-78. 1990..The principal, proven indication for performing PBC is to rule out or help rule in the diagnostic possibility of asthma as the cause of any unexplained chest complaints in patients with normal or near normal spirometric values...
Cough and gastroesophageal reflux: identifying cough and assessing the efficacy of cough-modifying agentsR S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Am J Med 111:45S-50S. 2001..Although it is theoretically possible to design and construct such a device that is also relatively unobtrusive, reliable, and accurate, one is not yet available...
Cough: a worldwide problemJ Mark Madison
Division of Pulmonary, Allergy and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Otolaryngol Clin North Am 43:1-13, vii. 2010....
Pharmacotherapy of chronic cough in adultsJ Mark Madison
Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01605 2324, USA
Expert Opin Pharmacother 4:1039-48. 2003..In contrast, non-specific therapy is used only in limited clinical settings, as it is directed at the symptom rather than underlying aetiologies and aims only to control, rather than eliminate cough...
A comparison of gender differences in health-related quality of life in acute and chronic coughersCynthia T French
Department of Medicine, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Chest 127:1991-8. 2005..Unlike CC, AC did not adversely affect the HRQOL of women more than men. The HRQOL of women is more adversely affected than the HRQOL of men, the longer a cough lasts...
Interpretation of positive results of a methacholine inhalation challenge and 1 week of inhaled bronchodilator use in diagnosing and treating cough-variant asthmaR S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, USA
Arch Intern Med 157:1981-7. 1997..The results are only diagnostic of asthma when they are followed by a favorable response to asthma therapy. After 1 week of inhaled beta-agonist, only the cough due to cough-variant asthma is significantly better...
Ex-smoker with productive cough, weight loss, and draining lesionRichard S Irwin
ACCP-SEEK program, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine University of Massachusetts Medical School, MA 01655, USA
Chest 122:1837-9. 2002
Diagnosis and treatment of chronic cough due to gastro-esophageal reflux disease and postnasal drip syndromeRichard S Irwin
Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA, USA
Pulm Pharmacol Ther 15:261-6. 2002..The second-generation, relatively non-sedating H(1)-antagonists have been found to be less effective than the first-generation agents in treating cough due to non-histamine-mediated PNDSs...
A prospective evaluation of the 1-hour decision point for admission versus discharge in acute asthmaMark M Wilson
Division of Pulmonary, Allergy and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655 0259, USA
J Intensive Care Med 18:275-85. 2003..The EPR-2 guideline thresholds for admission are barely adequate as outcome predictors. A clinical model is proposed that may allow more accurate outcome prediction...
Chemical analysis of freshly prepared and stored capsaicin solutions: implications for tussigenic challengesScott E Kopec
The Division of Pulmonary, Allergy, and Critical Care Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Pulm Pharmacol Ther 15:529-34. 2002..033). We conclude that the actual concentration of capsaicin solution is less than predicted, and solutions of 4 microM or higher concentration are stable for 1 year if stored at 4 degrees C protected from light...
Unsuspected bacterial suppurative disease of the airways presenting as chronic coughOren P Schaefer
Division of Pulmonary, Allergy and Critical Care Medicine, University of Massachusetts Medical School, Worcester, USA
Am J Med 114:602-6. 2003
Chronic cough due to gastroesophageal reflux disease: efficacy of antireflux surgeryY W Novitsky
Department of Surgery, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Surg Endosc 16:567-71. 2002..NF controls the severity of cough while improving the quality of life. Outcomes are further enhanced using laparoscopic procedures with shorter hospital stays...
A prospective global measure, the Punum Ladder, provides more valid assessments of quality of life than a retrospective transition measureKenneth E Fletcher
Department of Psychiatry, University of Massachusetts Medical School, Worcester, MA, USA
J Clin Epidemiol 63:1123-31. 2010....
Evaluation of a cough-specific quality-of-life questionnaireCynthia T French
Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Chest 121:1123-31. 2002..It is a valid and reliable method by which to assess the impact of cough on the quality of life of chronic and acute coughers, and the efficacy of cough therapies in chronic coughers...
Effect of triiodothyronine-induced thyrotoxicosis on airway hyperresponsivenessH M Hollingsworth
Division of Pulmonary, University of Massachusetts Medical School, Worcester 01655
J Appl Physiol 71:438-44. 1991..We conclude that mild T3-induced thyrotoxicosis of 4-wk duration had no effect on lung function, airway responsiveness, or exercise capacity in subjects with mild asthma...
Chronic cough in adults with interstitial lung diseaseJ Mark Madison
Division of Pulmonary, Allergy and Critical Care Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01605 2324, USA
Curr Opin Pulm Med 11:412-6. 2005....
Knee discomfort in a 38-year-old manRichard S Irwin
Dept. of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Chest 122:2242-5. 2002
American College of Chest Physicians' cough guidelinesRichard S Irwin
Lancet 367:981. 2006
An empiric integrative approach to the management of cough: ACCP evidence-based clinical practice guidelinesMelvin R Pratter
the Robert Wood Johnson School of Medicine at Camden, Suite 312, 3 Cooper Plaza, Camden, NJ 08103, USA
Chest 129:222S-231S. 2006..Review the literature to provide a comprehensive approach, including algorithms for the clinician to follow in evaluating and treating the patient with acute, subacute, and chronic cough...
Systemic corticosteroids for acute exacerbations of chronic obstructive pulmonary diseaseRichard S Irwin
N Engl J Med 348:2679-81. 2003
Guidelines for treating adults with acute coughRichard S Irwin
Am Fam Physician 75:476, 479, 482. 2007
Changing the work environment in intensive care units to achieve patient-focused care: the time has comeKathleen McCauley
The University of Pennsylvania School of Nursing and Hospital, Philadelphia, PA 19104 6096, USA
Am J Crit Care 15:541-8. 2006..Other innovative models of care delivery remain unreported. The successes and failures of these models should be shared with the professional community...
Changing the work environment in ICUs to achieve patient-focused care: the time has comeKathleen McCauley
University of Pennsylvania, School of Nursing and Hospital, Ardmore, PA 19003 1230, USA
Chest 130:1571-8. 2006..Other innovative models of care delivery remain unreported. The successes and failures of these models should be shared with the professional community...
Clinical trial registration promotes patient protection and benefit, advances the trust of everyone, and is requiredRichard S Irwin
Chest 131:639-41. 2007
Expectorated sputum for community-acquired pneumonia: a sacred cowJ Mark Madison
Arch Intern Med 164:1725-7. 2004
