D H Ingbar

Summary

Affiliation: University of Minnesota
Country: USA

Publications

  1. ncbi request reprint Mechanisms of repair and remodeling following acute lung injury
    D H Ingbar
    Department of Medicine, University of Minnesota School of Medicine, Minneapolis, USA
    Clin Chest Med 21:589-616. 2000
  2. ncbi request reprint Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice
    I Y Haddad
    Division of Pulmonary and Critical Care Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Physiol 277:L391-400. 1999
  3. ncbi request reprint High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation
    I Y Haddad
    Departments of Pediatrics and Pulmonary Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Respir Cell Mol Biol 20:1125-35. 1999
  4. pmc The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide
    A Panoskaltsis-Mortari
    Department of Pediatrics, BMT Division, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Clin Invest 100:1015-27. 1997
  5. ncbi request reprint KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT
    A Panoskaltsis-Mortari
    Department of Pediatrics, Division of Hematology Oncology and Bone Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Physiol Lung Cell Mol Physiol 278:L988-99. 2000
  6. pmc Oxidant effects on epithelial Na,K-ATPase gene expression and promoter function
    C H Wendt
    Department of Medicine, University of Minnesota School of Medicine, Minneapolis, USA
    Environ Health Perspect 106:1213-7. 1998
  7. ncbi request reprint Cl-channel activation is necessary for stimulation of Na transport in adult alveolar epithelial cells
    S M O'Grady
    Departments of Physiology and Animal Science, University of Minnesota, St Paul 55108, Minnesota 55455, USA
    Am J Physiol Lung Cell Mol Physiol 278:L239-44. 2000
  8. ncbi request reprint Up-regulation of Na,K-ATPase beta 1 transcription by hyperoxia is mediated by SP1/SP3 binding
    C H Wendt
    University of Minnesota, Department of Medicine, Minneapolis, Minnesota 55455, USA
    J Biol Chem 275:41396-404. 2000
  9. pmc Cell fusion to study nuclear-cytoplasmic interactions in endothelial cell apoptosis
    V A Polunovsky
    Department of Medicine, Pulmonary and Critical Care Division, University of Minnesota Medical School, Minneapolis, USA
    Am J Pathol 149:115-28. 1996
  10. ncbi request reprint The effects of hyperoxic injury and antioxidant vitamins on death and proliferation of human small airway epithelial cells
    H Jyonouchi
    Departments of Pediatrics and Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Respir Cell Mol Biol 19:426-36. 1998

Detail Information

Publications12

  1. ncbi request reprint Mechanisms of repair and remodeling following acute lung injury
    D H Ingbar
    Department of Medicine, University of Minnesota School of Medicine, Minneapolis, USA
    Clin Chest Med 21:589-616. 2000
    ..Intervention trials need to examine the long-term physiologic and functional outcomes...
  2. ncbi request reprint Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice
    I Y Haddad
    Division of Pulmonary and Critical Care Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Physiol 277:L391-400. 1999
    ..However, the presence of a nitrating agent impairs KGF-derived responses...
  3. ncbi request reprint High levels of peroxynitrite are generated in the lungs of irradiated mice given cyclophosphamide and allogeneic T cells. A potential mechanism of injury after marrow transplantation
    I Y Haddad
    Departments of Pediatrics and Pulmonary Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Respir Cell Mol Biol 20:1125-35. 1999
    ..NO, and that the addition of Cy favors peroxynitrite formation. Peroxynitrite generation clarifies the dependence of Cy-induced lung injury and lethality on the presence of allogeneic T cells...
  4. pmc The critical early proinflammatory events associated with idiopathic pneumonia syndrome in irradiated murine allogeneic recipients are due to donor T cell infusion and potentiated by cyclophosphamide
    A Panoskaltsis-Mortari
    Department of Pediatrics, BMT Division, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Clin Invest 100:1015-27. 1997
    ..This demonstration of early injury after BMT indicates the need for very early therapeutic intervention before lung damage becomes profound and irreversible...
  5. ncbi request reprint KGF pretreatment decreases B7 and granzyme B expression and hastens repair in lungs of mice after allogeneic BMT
    A Panoskaltsis-Mortari
    Department of Pediatrics, Division of Hematology Oncology and Bone Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Physiol Lung Cell Mol Physiol 278:L988-99. 2000
    ....
  6. pmc Oxidant effects on epithelial Na,K-ATPase gene expression and promoter function
    C H Wendt
    Department of Medicine, University of Minnesota School of Medicine, Minneapolis, USA
    Environ Health Perspect 106:1213-7. 1998
    ..Thus, hyperoxia induces Na,K-ATPase beta-1 promoter transcription, likely acting through a novel mechanism...
  7. ncbi request reprint Cl-channel activation is necessary for stimulation of Na transport in adult alveolar epithelial cells
    S M O'Grady
    Departments of Physiology and Animal Science, University of Minnesota, St Paul 55108, Minnesota 55455, USA
    Am J Physiol Lung Cell Mol Physiol 278:L239-44. 2000
    ..Finally, we describe some preliminary in vivo data that suggest a role for Cl-channel activation in the process of amiloride-sensitive alveolar fluid absorption...
  8. ncbi request reprint Up-regulation of Na,K-ATPase beta 1 transcription by hyperoxia is mediated by SP1/SP3 binding
    C H Wendt
    University of Minnesota, Department of Medicine, Minneapolis, Minnesota 55455, USA
    J Biol Chem 275:41396-404. 2000
    ..Other GC sites within the proximal promoter also demonstrated up-regulation of transcription by hyperoxia, however, the site at -55 had higher affinity for SP proteins...
  9. pmc Cell fusion to study nuclear-cytoplasmic interactions in endothelial cell apoptosis
    V A Polunovsky
    Department of Medicine, Pulmonary and Critical Care Division, University of Minnesota Medical School, Minneapolis, USA
    Am J Pathol 149:115-28. 1996
    ....
  10. ncbi request reprint The effects of hyperoxic injury and antioxidant vitamins on death and proliferation of human small airway epithelial cells
    H Jyonouchi
    Departments of Pediatrics and Internal Medicine, University of Minnesota, Minneapolis, Minnesota, USA
    Am J Respir Cell Mol Biol 19:426-36. 1998
    ..Although A549 cells underwent cell death mainly by necrosis, they also were influenced by cell density and hyperoxia. Cell density also determined specific antioxidant vitamin protection in SAE cells...
  11. ncbi request reprint Alveolar epithelial cells regulate the induction of endothelial cell apoptosis
    C H Wendt
    Department of Medicine, University of Minnesota School of Medicine, Minneapolis 55410
    Am J Physiol 267:C893-900. 1994
    ..Our results suggest that alveolar epithelial cells regulate the response of mesenchymal cells to factors that induce apoptosis during injury and repair...
  12. ncbi request reprint Human surfactant protein a suppresses T cell-dependent inflammation and attenuates the manifestations of idiopathic pneumonia syndrome in mice
    S Yang
    Department of Pediatrics, Division of Pulmonary and Critical Care, University of Minnesota, Minneapolis, Minnesota 55455, USA
    Am J Respir Cell Mol Biol 24:527-36. 2001
    ..We conclude that SP-A downregulates T cell-dependent alveolar inflammation by multiple pathways leading to decreased IPS injury...