Research Topics
Species | Premananda IndicSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
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Detail Information
Publications
Development of a two-dimension manifold to represent high dimension mathematical models of the intracellular Mammalian circadian clockPremananda Indic
Biomathematical Modeling Unit, Division of Sleep Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, MA, USA
J Biol Rhythms 21:222-32. 2006....
Dynamics of frequency flow in epileptic brain during extra-temporal partial and idiopathic generalized epilepsyPremananda Indic
Department of Neurology, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, MA 01655, USA
Epilepsy Res 99:176-9. 2012..The 5-12 Hz frequency flow was seen uniformly in all the channels in patients with IGE although it was seen most prominently adjacent to the seizure focus and to a lesser extent in other channels in patients with partial epilepsy...
A point process model of respiratory dynamics in early physiological developmentPremananda Indic
Department of Neurology, University of Massachusetts Medical School, MA 01655, USA
Conf Proc IEEE Eng Med Biol Soc 2011:3804-7. 2011..Our results validate the novel approach in the assessment of the irregularity of breathing by analyzing respiratory recordings from newborn rats and preterm infants...
Comparison of amplitude recovery dynamics of two limit cycle oscillator models of the human circadian pacemakerPremananda Indic
Biomathematical Modeling Unit, Division of Sleep Medicine, Brigham and Women s Hospital Harvard Medical School, Boston, MA, USA
Chronobiol Int 22:613-29. 2005..Experiments derived from model predictions are proposed to test the influence of low amplitude recovery on the physiological and neurobehavioral functions...
Scaling behavior of human locomotor activity amplitude: association with bipolar disorderPremananda Indic
Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
PLoS ONE 6:e20650. 2011....
Assessment of cardio-respiratory interactions in preterm infants by bivariate autoregressive modeling and surrogate data analysisPremananda Indic
Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Early Hum Dev 87:477-87. 2011....
Wavelet based algorithm for the estimation of frequency flow from electroencephalogram data during epileptic seizurePremananda Indic
Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01656, USA
Clin Neurophysiol 122:680-6. 2011..However the exact dynamics of the theta activity and its clinical significance are not known. In this work we present an approach using wavelets to study the frequency flow dynamics of this buildup...
Frequency flow dynamics of epileptic brainPremananda Indic
Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Int J Neurosci 120:222-5. 2010..We conclude that dynamics of frequency flow in the 5-12 Hz range can be a potential marker for the detection and/or the anticipation of the seizure in temporal lobe epilepsy...
Modeling the behavior of coupled cellular circadian oscillators in the suprachiasmatic nucleusPremananda Indic
Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Biol Rhythms 22:211-9. 2007..Mathematical approaches will be critical for better understanding intercellular interactions within the SCN...
Characterizing the amplitude dynamics of the human core-temperature circadian rhythm using a stochastic-dynamic modelPremananda Indic
Department of Neurology, University of Massachusetts Medical School, 55 Lake Ave North, Worcester, 01655, USA
J Theor Biol 239:499-506. 2006..We found that the circadian pacemaker recovers slowly to an equilibrium level following amplitude suppression. In humans this reaction to perturbation from equilibrium value has potential physiological implications...
Stabilizing immature breathing patterns of preterm infants using stochastic mechanosensory stimulationElisabeth Bloch-Salisbury
Department of Neurology, Univ of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
J Appl Physiol 107:1017-27. 2009..Our findings suggest that nonlinear properties of the immature respiratory control system can be harnessed using afferent stimuli to stabilize eupneic breathing, thereby potentially reducing the incidence of apnea and hypoxia...
Multi-scale motility amplitude associated with suicidal thoughts in major depressionPremananda Indic
Department of Neurology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
PLoS ONE 7:e38761. 2012..An objective biomarker of suicide-risk could be advantageous when patients are unwilling or unable to share suicidal thinking with clinicians...
Design principles for phase-splitting behaviour of coupled cellular oscillators: clues from hamsters with 'split' circadian rhythmsPremananda Indic
Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01655, USA
J R Soc Interface 5:873-83. 2008..We propose that a key design principle for the frequency doubling of a population of biological oscillators is inhomogeneity of oscillator coupling...
A role for the habenula in the regulation of locomotor activity cyclesMatthew J Paul
Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA
Eur J Neurosci 34:478-88. 2011..These data suggest a previously unrecognized function of the habenula whereby it regulates the temporal pattern of activity occurring within a circadian rest-activity window set by the suprachiasmatic nucleus...
Biological rhythms and mood disordersPaola Salvatore
Department of Psychiatry, Harvard Medical School and McLean Hospital, Boston, Massachusetts, USA
Dialogues Clin Neurosci 14:369-79. 2012....
Casein kinase 1 delta (CK1delta) regulates period length of the mouse suprachiasmatic circadian clock in vitroJean Pierre Etchegaray
Department of Neurobiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
PLoS ONE 5:e10303. 2010..Mice lacking CK1delta die shortly after birth, so it has not been possible to assess the impact of loss of CK1delta on behavioral rhythms controlled by the master circadian oscillator in the suprachiasmatic nuclei (SCN)...
