Yumi Imai

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Endocrinology 148:5716-23. 2007
  2. ncbi Analysis of gene expression in pancreatic islets from diet-induced obese mice
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Physiol Genomics 36:43-51. 2008
  3. ncbi Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice
    Hiralben R Patel
    University of Pennsylvania School of Medicine, Division of Endocrinology, Diabetes and Metabolism, 764 Clinical Research Building, 415 Curie Blvd, Philadelphia, PA 19104, USA
    Diabetes 55:3091-8. 2006
  4. ncbi Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19010, USA
    Gastroenterology 132:1947-54. 2007
  5. ncbi Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, and The Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104 5160, USA
    Physiol Genomics 44:1125-31. 2012

Research Grants

  1. Role of neuropeptide Y in diabetes and obesity
    Yumi Imai; Fiscal Year: 2007

Collaborators

Detail Information

Publications5

  1. ncbi Insulin secretion is increased in pancreatic islets of neuropeptide Y-deficient mice
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Endocrinology 148:5716-23. 2007
    ....
  2. ncbi Analysis of gene expression in pancreatic islets from diet-induced obese mice
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Physiol Genomics 36:43-51. 2008
    ..Functional analyses of differentially regulated genes hold promise for elucidating factors linking obesity to alterations in islet function...
  3. ncbi Neuropeptide Y deficiency attenuates responses to fasting and high-fat diet in obesity-prone mice
    Hiralben R Patel
    University of Pennsylvania School of Medicine, Division of Endocrinology, Diabetes and Metabolism, 764 Clinical Research Building, 415 Curie Blvd, Philadelphia, PA 19104, USA
    Diabetes 55:3091-8. 2006
    ..Insulin, leptin, and triglyceride levels increase with adiposity in both wild-type and NPYko mice...
  4. ncbi Reduction of hepatosteatosis and lipid levels by an adipose differentiation-related protein antisense oligonucleotide
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19010, USA
    Gastroenterology 132:1947-54. 2007
    ..We postulated that a reduction in ADRP would ameliorate hepatic steatosis and improve insulin action...
  5. ncbi Effects of perilipin 2 antisense oligonucleotide treatment on hepatic lipid metabolism and gene expression
    Yumi Imai
    Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, and The Institute for Diabetes, Obesity and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104 5160, USA
    Physiol Genomics 44:1125-31. 2012
    ..Plin2-ASO had similar effects on gene expression in chow-fed mice. Together, these results indicate that Plin2 has diverse metabolic and structural roles in the liver, and its downregulation promotes hepatic fibrosis and proliferation...

Research Grants2

  1. Role of neuropeptide Y in diabetes and obesity
    Yumi Imai; Fiscal Year: 2007
    ..Rexford Ahima and Dr. Franz Matschinsky. The division has expertise in diabetes and obesity research, and will provide an outstanding environment to conduct the proposed project. ..