Nola Hylton

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint MR imaging for assessment of breast cancer response to neoadjuvant chemotherapy
    Nola Hylton
    Department of Radiology, University of California, San Francisco, 1 Irving Street, Room AC 109, San Francisco, CA 94143 1290, USA
    Magn Reson Imaging Clin N Am 14:383-9, vii. 2006
  2. ncbi request reprint Magnetic resonance imaging of the breast: opportunities to improve breast cancer management
    Nola Hylton
    Department of Radiology, Magnetic Resonance Science Center, University of California San Francisco, 1 Irving St, Room AC 109, San Francisco, CA 94143 1290, USA
    J Clin Oncol 23:1678-84. 2005
  3. ncbi request reprint Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker
    Nola Hylton
    University of California, San Francisco, San Francisco, CA 94143 1290, USA
    J Clin Oncol 24:3293-8. 2006
  4. pmc Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657
    Laura J Esserman
    Breast Care Center, University of California at San Francisco, 1600 Divisadero St, 2nd Floor, Box 1710, San Francisco, CA 94115, USA
    J Clin Oncol 30:3242-9. 2012
  5. pmc Magnetic resonance imaging for secondary assessment of breast density in a high-risk cohort
    Catherine Klifa
    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94115 1667, USA
    Magn Reson Imaging 28:8-15. 2010
  6. pmc Clinically meaningful tumor reduction rates vary by prechemotherapy MRI phenotype and tumor subtype in the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
    Rita A Mukhtar
    University of California, San Francisco, San Francisco, CA, USA
    Ann Surg Oncol 20:3823-30. 2013
  7. pmc Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer
    Elisabeth R Garwood
    Department of Surgery, University of California, San Francisco, CA, USA
    Breast Cancer Res Treat 119:137-44. 2010
  8. doi request reprint Breast stromal enhancement on MRI is associated with response to neoadjuvant chemotherapy
    Jona Hattangadi
    Department of Radiology, Magnetic Resonance Science Center, 1 Irving St, Rm AC 109, Box 1290, University of California, San Francisco, San Francisco, CA 94143, USA
    AJR Am J Roentgenol 190:1630-6. 2008
  9. pmc Agreement of mammographic measures of volumetric breast density to MRI
    Jeff Wang
    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e81653. 2013
  10. pmc Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
    Laura J Esserman
    University of California San Francisco, 1600 Divisadero Street, Box 1710, San Francisco, CA 94115, USA
    Breast Cancer Res Treat 132:1049-62. 2012

Detail Information

Publications21

  1. ncbi request reprint MR imaging for assessment of breast cancer response to neoadjuvant chemotherapy
    Nola Hylton
    Department of Radiology, University of California, San Francisco, 1 Irving Street, Room AC 109, San Francisco, CA 94143 1290, USA
    Magn Reson Imaging Clin N Am 14:383-9, vii. 2006
    ..Functional measurements hold the promise of greater sensitivity for detecting biologic effects of targeted treatments than simple anatomic methods...
  2. ncbi request reprint Magnetic resonance imaging of the breast: opportunities to improve breast cancer management
    Nola Hylton
    Department of Radiology, Magnetic Resonance Science Center, University of California San Francisco, 1 Irving St, Room AC 109, San Francisco, CA 94143 1290, USA
    J Clin Oncol 23:1678-84. 2005
  3. ncbi request reprint Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarker
    Nola Hylton
    University of California, San Francisco, San Francisco, CA 94143 1290, USA
    J Clin Oncol 24:3293-8. 2006
    ..This article reviews the general methodology for performing DCE-MRI and discusses existing data and challenges to applying DCE-MRI for treatment response assessment in clinical trials...
  4. pmc Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657
    Laura J Esserman
    Breast Care Center, University of California at San Francisco, 1600 Divisadero St, 2nd Floor, Box 1710, San Francisco, CA 94115, USA
    J Clin Oncol 30:3242-9. 2012
    ....
  5. pmc Magnetic resonance imaging for secondary assessment of breast density in a high-risk cohort
    Catherine Klifa
    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94115 1667, USA
    Magn Reson Imaging 28:8-15. 2010
    ..Magnetic resonance imaging density could potentially be quantified and used for a better assessment of breast cancer risk in these populations...
  6. pmc Clinically meaningful tumor reduction rates vary by prechemotherapy MRI phenotype and tumor subtype in the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
    Rita A Mukhtar
    University of California, San Francisco, San Francisco, CA, USA
    Ann Surg Oncol 20:3823-30. 2013
    ....
  7. pmc Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancer
    Elisabeth R Garwood
    Department of Surgery, University of California, San Francisco, CA, USA
    Breast Cancer Res Treat 119:137-44. 2010
    ..Effects were only evident in high grade tumors. These results support further evaluation of statins as chemoprevention for ER-negative high grade breast cancers...
  8. doi request reprint Breast stromal enhancement on MRI is associated with response to neoadjuvant chemotherapy
    Jona Hattangadi
    Department of Radiology, Magnetic Resonance Science Center, 1 Irving St, Rm AC 109, Box 1290, University of California, San Francisco, San Francisco, CA 94143, USA
    AJR Am J Roentgenol 190:1630-6. 2008
    ....
  9. pmc Agreement of mammographic measures of volumetric breast density to MRI
    Jeff Wang
    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 8:e81653. 2013
    ..Automated technologies for mammography exist to quantify breast density objectively, but the technique that most accurately measures the quantity of breast fibroglandular tissue is not known...
  10. pmc Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)
    Laura J Esserman
    University of California San Francisco, 1600 Divisadero Street, Box 1710, San Francisco, CA 94115, USA
    Breast Cancer Res Treat 132:1049-62. 2012
    ..The ability of pCR to predict RFS is better by subset than it is for the whole group. Molecular markers improve prediction of RFS by identifying additional patients with excellent prognosis within the no pCR group...
  11. ncbi request reprint Role of breast MR imaging in neoadjuvant chemotherapy
    H Carisa Le-Petross
    Department of Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1350, Houston, TX 77030, USA
    Magn Reson Imaging Clin N Am 18:249-58, viii-ix. 2010
    ..However, there is still no consensus on the role of MR imaging for assessing response to neoadjuvant chemotherapy or on a standardized MR imaging examination in patients receiving neoadjuvant chemotherapy...
  12. pmc Topographic enhancement mapping of the cancer-associated breast stroma using breast MRI
    Nima Nabavizadeh
    Department of Radiation Oncology, University of California, San Francisco Comprehensive Cancer Center, 1600 Divisadero Street H1031, San Francisco, CA 94143 1708, USA
    Integr Biol (Camb) 3:490-6. 2011
    ..Identification of a cancer-associated stroma may be further developed to help guide local therapy to reduce recurrence and morbidity in breast cancer patients...
  13. ncbi request reprint The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situ
    Kaoru Itakura
    Department of Surgery, University of California, San Francisco, USA
    Clin Breast Cancer 11:33-8. 2011
    ..We sought to determine whether preoperative MRI affects surgical treatment and outcomes in women with pure DCIS...
  14. pmc Biologic significance of false-positive magnetic resonance imaging enhancement in the setting of ductal carcinoma in situ
    Anjali S Kumar
    Department of Surgery, University of California San Francisco, San Francisco, CA, USA
    Am J Surg 192:520-4. 2006
    ..We investigated the pathologic and biologic characteristics of false positive enhancement by breast MRI...
  15. ncbi request reprint Diagnostic architectural and dynamic features at breast MR imaging: multicenter study
    Mitchell D Schnall
    Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
    Radiology 238:42-53. 2006
    ..To prospectively determine the prevalence and predictive value of three-dimensional (3D) and dynamic breast magnetic resonance (MR) imaging and contrast material kinetic features alone and as part of predictive diagnostic models...
  16. ncbi request reprint MRI detection of distinct incidental cancer in women with primary breast cancer studied in IBMC 6883
    Mitchell D Schnall
    Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    J Surg Oncol 92:32-8. 2005
    ..We report on the rate of MRI and mammography detection of foci of distinct incidental cancer in a prospective, multi center trial involving 426 women with confirmed breast cancer at 15 institutions in the US, Canada, and Germany...
  17. ncbi request reprint Added cancer yield of MRI in screening the contralateral breast of women recently diagnosed with breast cancer: results from the International Breast Magnetic Resonance Consortium (IBMC) trial
    Constance D Lehman
    Department of Radiology, University of Washington, Seattle Cancer Care Alliance, Seattle, Washington 98109, USA
    J Surg Oncol 92:9-15; discussion 15-6. 2005
    ..To estimate the added cancer yield of magnetic resonance imaging (MRI) over mammography in the contralateral breast of patients with a recent diagnosis of breast cancer...
  18. ncbi request reprint Screening women at high risk for breast cancer with mammography and magnetic resonance imaging
    Constance D Lehman
    Department of Radiology, University of Washington, Seattle Cancer Care Alliance, Seattle, Washington 98109 1023, USA
    Cancer 103:1898-905. 2005
    ..The authors compared the performance of screening mammography versus magnetic resonance imaging (MRI) in women at genetically high risk for breast cancer...
  19. pmc Four-phase single-capillary stepwise model for kinetics in arterial spin labeling MRI
    Ka Loh Li
    Department of Radiology, University of California San Francisco, and VA Medical Center 114M, 4150 Clement Street, San Francisco, CA 94121, USA
    Magn Reson Med 53:511-8. 2005
    ..055). These results imply that restricted permeability of capillaries to water should be considered when brain ASL data are analyzed...
  20. ncbi request reprint Combined diffuse optical spectroscopy and contrast-enhanced magnetic resonance imaging for monitoring breast cancer neoadjuvant chemotherapy: a case study
    Natasha Shah
    University of California Irvine, Beckman Laser Institute and Medical Clinic, Laser Microbeam and Medical Program, Irvine, California 92162 1475, USA
    J Biomed Opt 10:051503. 2005
    ..7% drop in mean total hemoglobin content (THC, 41.6 versus 23.4 microM). These data provide in vivo validation of the accuracy of broadband DOS and the sensitivity of optical methods to changes in tumor physiology...
  21. ncbi request reprint Magnetic resonance imaging of the breast prior to biopsy
    David A Bluemke
    Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    JAMA 292:2735-42. 2004
    ..Breast magnetic resonance imaging (MRI) has been shown to have high sensitivity for cancer detection and is increasingly used following mammography to evaluate suspicious breast lesions...

Research Grants19

  1. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola M Hylton; Fiscal Year: 2010
    ..Aim 3 will apply new statistical approaches for optimally combining markers in a predictive model. ..
  2. Real-time In Vivo MRI Biomarkers for Breast Cancer Pre-operative Treatment Trials
    Nola M Hylton; Fiscal Year: 2010
    ..This project will also support the optimization and comparison of MRI-based imaging biomarkers based on clinical outcomes. ..
  3. MRI For Staging DCIS and Assessing Response to Treatment
    Nola Hylton; Fiscal Year: 2009
    ..The pilot trials afford an opportunity to refine MRI methods for DCIS and to improve their effectiveness for guiding patient selection and treatment assessment. ..
  4. Real-time In Vivo MRI Biomarkers for Breast Cancer Pre-operative Treatment Trials
    Nola Hylton; Fiscal Year: 2009
    ..This project will also support the optimization and comparison of MRI-based imaging biomarkers based on clinical outcomes. ..
  5. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2009
    ..Aim 3 will apply new statistical approaches for optimally combining markers in a predictive model. ..
  6. MRI For Staging DCIS and Assessing Response to Treatment
    Nola Hylton; Fiscal Year: 2007
    ..The pilot trials afford an opportunity to refine MRI methods for DCIS and to improve their effectiveness for guiding patient selection and treatment assessment. ..
  7. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2007
    ..Aim 3 will apply new statistical approaches for optimally combining markers in a predictive model. ..
  8. MRI For Staging DCIS and Assessing Response to Treatment
    Nola Hylton; Fiscal Year: 2006
    ..The pilot trials afford an opportunity to refine MRI methods for DCIS and to improve their effectiveness for guiding patient selection and treatment assessment. ..
  9. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2006
    ..Aim 3 will apply new statistical approaches for optimally combining markers in a predictive model. ..
  10. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2005
    ..MRI methods will be developed using both standard gadolinium-DTPA and gadolinium-encapsulating immunoliposomes. ..
  11. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2004
    ..MRI methods will be developed using both standard gadolinium-DTPA and gadolinium-encapsulating immunoliposomes. ..
  12. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2003
    ..MRI methods will be developed using both standard gadolinium-DTPA and gadolinium-encapsulating immunoliposomes. ..
  13. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2002
    ..MRI methods will be developed using both standard gadolinium-DTPA and gadolinium-encapsulating immunoliposomes. ..
  14. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 2001
    ..MRI methods will be developed using both standard gadolinium-DTPA and gadolinium-encapsulating immunoliposomes. ..
  15. ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRI
    Nola Hylton; Fiscal Year: 1999
    ..It is expected that this resource will contribute to our increased knowledge and understanding of breast cancer. ..
  16. MRI For Staging DCIS and Assessing Response to Treatment
    Nola M Hylton; Fiscal Year: 2010
    ..The pilot trials afford an opportunity to refine MRI methods for DCIS and to improve their effectiveness for guiding patient selection and treatment assessment. ..