Affiliation: University of California
- MR imaging for assessment of breast cancer response to neoadjuvant chemotherapyNola Hylton
Department of Radiology, University of California, San Francisco, 1 Irving Street, Room AC 109, San Francisco, CA 94143 1290, USA
Magn Reson Imaging Clin N Am 14:383-9, vii. 2006..Functional measurements hold the promise of greater sensitivity for detecting biologic effects of targeted treatments than simple anatomic methods...
- Dynamic contrast-enhanced magnetic resonance imaging as an imaging biomarkerNola Hylton
University of California, San Francisco, San Francisco, CA 94143 1290, USA
J Clin Oncol 24:3293-8. 2006..This article reviews the general methodology for performing DCE-MRI and discusses existing data and challenges to applying DCE-MRI for treatment response assessment in clinical trials...
- Magnetic resonance imaging of the breast: opportunities to improve breast cancer managementNola Hylton
Department of Radiology, Magnetic Resonance Science Center, University of California San Francisco, 1 Irving St, Room AC-109, San Francisco, CA 94143-1290, USA
J Clin Oncol 23:1678-84. 2005
- Pathologic complete response predicts recurrence-free survival more effectively by cancer subset: results from the I-SPY 1 TRIAL--CALGB 150007/150012, ACRIN 6657Laura J Esserman
Breast Care Center, University of California at San Francisco, 1600 Divisadero St, 2nd Floor, Box 1710, San Francisco, CA 94115, USA
J Clin Oncol 30:3242-9. 2012....
- Magnetic resonance imaging for secondary assessment of breast density in a high-risk cohortCatherine Klifa
Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA 94115 1667, USA
Magn Reson Imaging 28:8-15. 2010..Magnetic resonance imaging density could potentially be quantified and used for a better assessment of breast cancer risk in these populations...
- Fluvastatin reduces proliferation and increases apoptosis in women with high grade breast cancerElisabeth R Garwood
Department of Surgery, University of California, San Francisco, CA, USA
Breast Cancer Res Treat 119:137-44. 2010..Effects were only evident in high grade tumors. These results support further evaluation of statins as chemoprevention for ER-negative high grade breast cancers...
- Breast stromal enhancement on MRI is associated with response to neoadjuvant chemotherapyJona Hattangadi
Department of Radiology, Magnetic Resonance Science Center, 1 Irving St, Rm AC 109, Box 1290, University of California, San Francisco, San Francisco, CA 94143, USA
AJR Am J Roentgenol 190:1630-6. 2008....
- Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)Laura J Esserman
University of California San Francisco, 1600 Divisadero Street, Box 1710, San Francisco, CA 94115, USA
Breast Cancer Res Treat 132:1049-62. 2012..The ability of pCR to predict RFS is better by subset than it is for the whole group. Molecular markers improve prediction of RFS by identifying additional patients with excellent prognosis within the no pCR group...
- Role of breast MR imaging in neoadjuvant chemotherapyH Carisa Le-Petross
Department of Radiology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1350, Houston, TX 77030, USA
Magn Reson Imaging Clin N Am 18:249-58, viii-ix. 2010..However, there is still no consensus on the role of MR imaging for assessing response to neoadjuvant chemotherapy or on a standardized MR imaging examination in patients receiving neoadjuvant chemotherapy...
- Topographic enhancement mapping of the cancer-associated breast stroma using breast MRINima Nabavizadeh
Department of Radiation Oncology, University of California, San Francisco Comprehensive Cancer Center, 1600 Divisadero Street H1031, San Francisco, CA 94143 1708, USA
Integr Biol (Camb) 3:490-6. 2011..Identification of a cancer-associated stroma may be further developed to help guide local therapy to reduce recurrence and morbidity in breast cancer patients...
- The impact of preoperative magnetic resonance imaging on surgical treatment and outcomes for ductal carcinoma in situKaoru Itakura
Department of Surgery, University of California, San Francisco, USA
Clin Breast Cancer 11:33-8. 2011..We sought to determine whether preoperative MRI affects surgical treatment and outcomes in women with pure DCIS...
- Biologic significance of false-positive magnetic resonance imaging enhancement in the setting of ductal carcinoma in situAnjali S Kumar
Department of Surgery, University of California San Francisco, San Francisco, CA, USA
Am J Surg 192:520-4. 2006..Benign proliferative processes often enhance on MRI and are difficult to differentiate from low-grade, ER+ DCIS lesions. False-positive MRI enhancement may reflect a spectrum of change within high-risk tissue...
- Diagnostic architectural and dynamic features at breast MR imaging: multicenter studyMitchell D Schnall
Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia, PA 19104, USA
Radiology 238:42-53. 2006..To prospectively determine the prevalence and predictive value of three-dimensional (3D) and dynamic breast magnetic resonance (MR) imaging and contrast material kinetic features alone and as part of predictive diagnostic models...
- MRI detection of distinct incidental cancer in women with primary breast cancer studied in IBMC 6883Mitchell D Schnall
Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
J Surg Oncol 92:32-8. 2005..We report on the rate of MRI and mammography detection of foci of distinct incidental cancer in a prospective, multi center trial involving 426 women with confirmed breast cancer at 15 institutions in the US, Canada, and Germany...
- Added cancer yield of MRI in screening the contralateral breast of women recently diagnosed with breast cancer: results from the International Breast Magnetic Resonance Consortium (IBMC) trialConstance D Lehman
Department of Radiology, University of Washington, Seattle Cancer Care Alliance, Seattle, Washington 98109, USA
J Surg Oncol 92:9-15; discussion 15-6. 2005..To estimate the added cancer yield of magnetic resonance imaging (MRI) over mammography in the contralateral breast of patients with a recent diagnosis of breast cancer...
- Screening women at high risk for breast cancer with mammography and magnetic resonance imagingConstance D Lehman
Department of Radiology, University of Washington, Seattle Cancer Care Alliance, Seattle, Washington 98109 1023, USA
Cancer 103:1898-905. 2005..The authors compared the performance of screening mammography versus magnetic resonance imaging (MRI) in women at genetically high risk for breast cancer...
- Four-phase single-capillary stepwise model for kinetics in arterial spin labeling MRIKa-loh Li
Department of Radiology, University of California-San Francisco, and VA Medical Center 114M, 4150 Clement Street, San Francisco, CA 94121, USA
Magn Reson Med 53:511-8. 2005..055). These results imply that restricted permeability of capillaries to water should be considered when brain ASL data are analyzed...
- Combined diffuse optical spectroscopy and contrast-enhanced magnetic resonance imaging for monitoring breast cancer neoadjuvant chemotherapy: a case studyNatasha Shah
University of California-Irvine, Beckman Laser Institute and Medical Clinic, Laser Microbeam and Medical Program, Irvine, California 92162-1475, USA
J Biomed Opt 10:051503. 2005..7% drop in mean total hemoglobin content (THC, 41.6 versus 23.4 microM). These data provide in vivo validation of the accuracy of broadband DOS and the sensitivity of optical methods to changes in tumor physiology...
- Magnetic resonance imaging of the breast prior to biopsyDavid A Bluemke
Russell H Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA
JAMA 292:2735-42. 2004..Breast magnetic resonance imaging (MRI) has been shown to have high sensitivity for cancer detection and is increasingly used following mammography to evaluate suspicious breast lesions...
- ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRINola M Hylton; Fiscal Year: 2010..Aim 3 will apply new statistical approaches for optimally combining markers in a predictive model. ..
- Real-time In Vivo MRI Biomarkers for Breast Cancer Pre-operative Treatment TrialsNola M Hylton; Fiscal Year: 2010..This project will also support the optimization and comparison of MRI-based imaging biomarkers based on clinical outcomes. ..
- MRI For Staging DCIS and Assessing Response to TreatmentNola Hylton; Fiscal Year: 2007..The pilot trials afford an opportunity to refine MRI methods for DCIS and to improve their effectiveness for guiding patient selection and treatment assessment. ..
- ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRINola Hylton; Fiscal Year: 2007..Aim 3 will apply new statistical approaches for optimally combining markers in a predictive model. ..
- ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRINola Hylton; Fiscal Year: 2005..MRI methods will be developed using both standard gadolinium-DTPA and gadolinium-encapsulating immunoliposomes. ..
- ANATOMIC AND BIOLOGIC STAGING OF BREAST DISEASE WITH MRINola Hylton; Fiscal Year: 1999..It is expected that this resource will contribute to our increased knowledge and understanding of breast cancer. ..
- MRI For Staging DCIS and Assessing Response to TreatmentNola M Hylton; Fiscal Year: 2010..The pilot trials afford an opportunity to refine MRI methods for DCIS and to improve their effectiveness for guiding patient selection and treatment assessment. ..