David S Hydock

Summary

Affiliation: University of Northern Colorado
Country: USA

Publications

  1. doi request reprint Switching to a low-fat diet attenuates the intensified doxorubicin cardiotoxicity associated with high-fat feeding
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Cancer Chemother Pharmacol 71:1551-60. 2013
  2. ncbi request reprint Characterization of the effect of in vivo doxorubicin treatment on skeletal muscle function in the rat
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Gunter Hall 2590, Box39, 501 20th Street, Greeley, CO 80639, USA
    Anticancer Res 31:2023-8. 2011
  3. doi request reprint Effects of endurance training on combined goserelin acetate and doxorubicin treatment-induced cardiac dysfunction
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Cancer Chemother Pharmacol 68:685-92. 2011
  4. doi request reprint Rehabilitative exercise in a rat model of doxorubicin cardiotoxicity
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Exp Biol Med (Maywood) 237:1483-92. 2012
  5. doi request reprint Exercise preconditioning protects against doxorubicin-induced cardiac dysfunction
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Med Sci Sports Exerc 40:808-17. 2008
  6. doi request reprint Exercise preconditioning provides long-term protection against early chronic doxorubicin cardiotoxicity
    David S Hydock
    University of Northern Colorado, Greeley, CO 80639, USA
    Integr Cancer Ther 10:47-57. 2011
  7. doi request reprint Voluntary wheel running in growing rats does not protect against doxorubicin-induced osteopenia
    Reid Hayward
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    J Pediatr Hematol Oncol 35:e144-8. 2013
  8. ncbi request reprint Voluntary wheel running in rats receiving doxorubicin: effects on running activity and cardiac myosin heavy chain
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Anticancer Res 29:4401-7. 2009
  9. ncbi request reprint Effects of voluntary wheel running on cardiac function and myosin heavy chain in chemically gonadectomized rats
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Am J Physiol Heart Circ Physiol 293:H3254-64. 2007
  10. doi request reprint Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, Colorado 80639, USA
    J Cardiovasc Pharmacol Ther 14:59-67. 2009

Collaborators

Detail Information

Publications16

  1. doi request reprint Switching to a low-fat diet attenuates the intensified doxorubicin cardiotoxicity associated with high-fat feeding
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Cancer Chemother Pharmacol 71:1551-60. 2013
    ..The purpose of this study was to investigate the effects of a low-fat diet on DOX-induced cardiotoxicity in rats previously fed a high-fat diet...
  2. ncbi request reprint Characterization of the effect of in vivo doxorubicin treatment on skeletal muscle function in the rat
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Gunter Hall 2590, Box39, 501 20th Street, Greeley, CO 80639, USA
    Anticancer Res 31:2023-8. 2011
    ..The purpose of this study was to characterize the muscle function dose-response to DOX. A secondary purpose was to compare the degree of DOX-induced muscle dysfunction to the observed cardiac dysfunction...
  3. doi request reprint Effects of endurance training on combined goserelin acetate and doxorubicin treatment-induced cardiac dysfunction
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Cancer Chemother Pharmacol 68:685-92. 2011
    ....
  4. doi request reprint Rehabilitative exercise in a rat model of doxorubicin cardiotoxicity
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Exp Biol Med (Maywood) 237:1483-92. 2012
    ....
  5. doi request reprint Exercise preconditioning protects against doxorubicin-induced cardiac dysfunction
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Med Sci Sports Exerc 40:808-17. 2008
    ..Evidence is mounting that exercise protects against DOX-related cardiac dysfunction, and as such, it may be possible that prior endurance training promotes defense against DOX cardiotoxicity...
  6. doi request reprint Exercise preconditioning provides long-term protection against early chronic doxorubicin cardiotoxicity
    David S Hydock
    University of Northern Colorado, Greeley, CO 80639, USA
    Integr Cancer Ther 10:47-57. 2011
    ....
  7. doi request reprint Voluntary wheel running in growing rats does not protect against doxorubicin-induced osteopenia
    Reid Hayward
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    J Pediatr Hematol Oncol 35:e144-8. 2013
    ..Exercise failed to protect bones from the damaging effects of DOX. Other modalities may be necessary to mitigate the deleterious skeletal effects that occur in juveniles undergoing treatment with anthracyclines...
  8. ncbi request reprint Voluntary wheel running in rats receiving doxorubicin: effects on running activity and cardiac myosin heavy chain
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Anticancer Res 29:4401-7. 2009
    ..Exercise prior to DOX treatment has been shown to attenuate the MHC shift associated with DOX, but little is known about the cardioprotective nature of exercise during DOX treatment...
  9. ncbi request reprint Effects of voluntary wheel running on cardiac function and myosin heavy chain in chemically gonadectomized rats
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, CO 80639, USA
    Am J Physiol Heart Circ Physiol 293:H3254-64. 2007
    ..Thus an 8-wk chemical gonadectomy with Zoladex promoted cardiac dysfunction in male and female rats, and voluntary wheel running protected against this cardiac dysfunction...
  10. doi request reprint Anandamide preserves cardiac function and geometry in an acute doxorubicin cardiotoxicity rat model
    David S Hydock
    School of Sport and Exercise Science, University of Northern Colorado, Greeley, Colorado 80639, USA
    J Cardiovasc Pharmacol Ther 14:59-67. 2009
    ..05). These results suggest that a potential therapy for doxorubicin-induced cardiotoxicity involves targeting the endogenous cannabinoid system...
  11. doi request reprint Exercise training mitigates anthracycline-induced chronic cardiotoxicity in a juvenile rat model
    Reid Hayward
    School of Sport and Exercise Science and the Rocky Mountain Cancer Rehabilitation Institute, University of Northern Colorado, Greeley, Colorado 80639, USA
    Pediatr Blood Cancer 59:149-54. 2012
    ..The aim of the present study was to determine if exercise training provides cardioprotection in a juvenile rat model of delayed-onset anthracycline cardiotoxicity...
  12. doi request reprint Exercise mitigates cardiac doxorubicin accumulation and preserves function in the rat
    Brock T Jensen
    School of Sport and Exercise Science and the Rocky Mountain Cancer Rehabilitation Institute, University of Northern Colorado, Greeley, CO Department of Exercise and Rehabilitative Sciences, Slippery Rock University, Slippery Rock, PA and Department of Athletics, National Taiwan University, Taipei, Taiwan
    J Cardiovasc Pharmacol 62:263-9. 2013
    ..The purpose of this study was to determine if exercise training reduces cardiac DOX accumulation, thereby providing a possible mechanism to explain the cardioprotective effects of exercise against DOX toxicity...
  13. ncbi request reprint Effects of voluntary wheel running on goserelin acetate-induced bone degeneration
    David S Hydock
    School of Sport and Exercise Science and the Rocky Mountain Cancer Rehabilitation Institute, University of Northern Colorado, Greeley, CO, United States
    Pathophysiology 15:253-9. 2008
    ..05). The current report indicates that 8 weeks of GA treatment promotes cancellous bone degeneration, and voluntary wheel running provides no clear osteoprotection in growing male and female rats...
  14. ncbi request reprint Low-intensity exercise training during doxorubicin treatment protects against cardiotoxicity
    Adam J Chicco
    School of Sport and Exercise Science, Univ of Northern Colorado, Greeley, CO 80639, USA
    J Appl Physiol 100:519-27. 2006
    ..In conclusion, our data suggest that LIET applied during chronic Dox treatment protects against cardiac dysfunction following treatment, possibly by enhancing antioxidant defenses and inhibiting apoptosis...
  15. ncbi request reprint Doxorubicin cardiotoxicity in the rat: an in vivo characterization
    Reid Hayward
    School of Sport and Exercise, and the Rocky Mountain Cancer Rehabilitation Institute, University of Northern Colorado, Greeley, CO, USA
    J Am Assoc Lab Anim Sci 46:20-32. 2007
    ....
  16. doi request reprint Doxorubicin-induced vascular dysfunction and its attenuation by exercise preconditioning
    Noah M Gibson
    School of Sport and Exercise Science and the Rocky Mountain Cancer Rehabilitation Institute, University of Northern Colorado, Greeley, CO
    J Cardiovasc Pharmacol 62:355-60. 2013
    ..These results suggest that chronic exercise attenuates vascular smooth muscle dysfunction associated with DOX treatment and seems to be independent of DOX accumulation in vascular tissue...