Krystel Huxlin

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Topical rosiglitazone is an effective anti-scarring agent in the cornea
    Krystel R Huxlin
    Flaum Eye Institute, University of Rochester, Rochester, New York, United States of America
    PLoS ONE 8:e70785. 2013
  2. pmc Perceptual relearning of complex visual motion after V1 damage in humans
    Krystel R Huxlin
    University of Rochester Eye Institute, Rochester, New York 14642, USA
    J Neurosci 29:3981-91. 2009
  3. doi request reprint Perceptual plasticity in damaged adult visual systems
    Krystel R Huxlin
    Department of Ophthalmology, Neurobiology and Anatomy and Center for Visual Science, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Vision Res 48:2154-66. 2008
  4. pmc A neurochemical signature of visual recovery after extrastriate cortical damage in the adult cat
    Krystel R Huxlin
    Department of Ophthalmology, University of Rochester, Rochester, New York 14642
    J Comp Neurol 508:45-61. 2008
  5. ncbi request reprint Monochromatic ocular wavefront aberrations in the awake-behaving cat
    Krystel R Huxlin
    Department of Ophthalmology, University of Rochester, Rochester, NY 14627, USA
    Vision Res 44:2159-69. 2004
  6. ncbi request reprint Deficits in complex visual perception following unilateral temporal lobectomy
    K R Huxlin
    University of Rochester Medical Center Department of Ophthalmology Rochester NY US Box 314 14642, USA
    J Cogn Neurosci 10:395-407. 1998
  7. ncbi request reprint Training-induced recovery of visual motion perception after extrastriate cortical damage in the adult cat
    Krystel R Huxlin
    Department of Ophthalmology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cereb Cortex 14:81-90. 2004
  8. ncbi request reprint Long-term neurochemical changes after visual cortical lesions in the adult cat
    K R Huxlin
    Department of Ophthalmology, University of Rochester, Rochester, New York 14642, USA
    J Comp Neurol 429:221-41. 2001
  9. ncbi request reprint Perceptual deficits after lesions of inferotemporal cortex in macaques
    K R Huxlin
    Department of Ophthalmology and Center for Visual Science, University of Rochester Medical Center, Rochester, NY 14642, USA
    Cereb Cortex 10:671-83. 2000
  10. pmc Contribution of optical zone decentration and pupil dilation on the change of optical quality after myopic photorefractive keratectomy in a cat model
    Jens Bühren
    University of Rochester Eye Institute, University of Rochester Medical Center, Rochester, NY, USA
    J Refract Surg 26:183-90. 2010

Collaborators

Detail Information

Publications18

  1. pmc Topical rosiglitazone is an effective anti-scarring agent in the cornea
    Krystel R Huxlin
    Flaum Eye Institute, University of Rochester, Rochester, New York, United States of America
    PLoS ONE 8:e70785. 2013
    ..Its topical application may represent an effective, new avenue for the prevention of corneal scarring with distinct advantages for pathologically thin corneas...
  2. pmc Perceptual relearning of complex visual motion after V1 damage in humans
    Krystel R Huxlin
    University of Rochester Eye Institute, Rochester, New York 14642, USA
    J Neurosci 29:3981-91. 2009
    ....
  3. doi request reprint Perceptual plasticity in damaged adult visual systems
    Krystel R Huxlin
    Department of Ophthalmology, Neurobiology and Anatomy and Center for Visual Science, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Vision Res 48:2154-66. 2008
    ..However, damage may alter visual plasticity in ways that are still being defined...
  4. pmc A neurochemical signature of visual recovery after extrastriate cortical damage in the adult cat
    Krystel R Huxlin
    Department of Ophthalmology, University of Rochester, Rochester, New York 14642
    J Comp Neurol 508:45-61. 2008
    ..This supports our hypothesis that stimulation of early visual cortical areas-in this case, area 18-by training is an important factor in restoring visual perception after permanent damage to LS cortex...
  5. ncbi request reprint Monochromatic ocular wavefront aberrations in the awake-behaving cat
    Krystel R Huxlin
    Department of Ophthalmology, University of Rochester, Rochester, NY 14627, USA
    Vision Res 44:2159-69. 2004
    ..95 degrees. These results form a solid basis for future wavefront sensing studies aiming to quantify the effects of ocular manipulations in experimental animals...
  6. ncbi request reprint Deficits in complex visual perception following unilateral temporal lobectomy
    K R Huxlin
    University of Rochester Medical Center Department of Ophthalmology Rochester NY US Box 314 14642, USA
    J Cogn Neurosci 10:395-407. 1998
    ..Our results indicate that temporal lobe damage disrupts complex, but not simple, visual discriminations throughout the visual field...
  7. ncbi request reprint Training-induced recovery of visual motion perception after extrastriate cortical damage in the adult cat
    Krystel R Huxlin
    Department of Ophthalmology, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cereb Cortex 14:81-90. 2004
    ..These results suggest that recovery of complex visual motion perception after lesions of extrastriate visual cortex is an active process that requires extensive, stimulus- and retinotopically-specific visual retraining...
  8. ncbi request reprint Long-term neurochemical changes after visual cortical lesions in the adult cat
    K R Huxlin
    Department of Ophthalmology, University of Rochester, Rochester, New York 14642, USA
    J Comp Neurol 429:221-41. 2001
    ..That changes were restricted to calbindin expression suggests cell-specific and/or biochemical pathway-specific alterations in calcium homeostasis...
  9. ncbi request reprint Perceptual deficits after lesions of inferotemporal cortex in macaques
    K R Huxlin
    Department of Ophthalmology and Center for Visual Science, University of Rochester Medical Center, Rochester, NY 14642, USA
    Cereb Cortex 10:671-83. 2000
    ....
  10. pmc Contribution of optical zone decentration and pupil dilation on the change of optical quality after myopic photorefractive keratectomy in a cat model
    Jens Bühren
    University of Rochester Eye Institute, University of Rochester Medical Center, Rochester, NY, USA
    J Refract Surg 26:183-90. 2010
    ..To simulate the simultaneous contribution of optical zone decentration and pupil dilation on retinal image quality using wavefront error data from a myopic photorefractive keratectomy (PRK) cat model...
  11. pmc The effect of optical zone decentration on lower- and higher-order aberrations after photorefractive keratectomy in a cat model
    Jens Bühren
    Department of Ophthalmology, University of Rochester Medical Center, NY 14642, USA
    Invest Ophthalmol Vis Sci 48:5806-14. 2007
    ..To simulate the effects of decentration on lower- and higher-order aberrations (LOAs and HOAs) and optical quality, by using measured wavefront error (WFE) data from a cat photorefractive keratectomy (PRK) model...
  12. pmc Differences in the TGF-{beta}1-induced profibrotic response of anterior and posterior corneal keratocytes in vitro
    Holly B Hindman
    Flaum Eye Institute, University of Rochester Medical Center, Rochester, New York, USA
    Invest Ophthalmol Vis Sci 51:1935-42. 2010
    ..This heterogeneity of keratocyte response may impact wound closure after mechanical wounding...
  13. pmc Optical effects of anti-TGFbeta treatment after photorefractive keratectomy in a cat model
    Jens Bühren
    University of Rochester Eye Institute, University of Rochester, Rochester, New York 14642, USA
    Invest Ophthalmol Vis Sci 50:634-43. 2009
    ..To assess the contribution of corneal myofibroblasts to optical changes induced by photorefractive keratectomy (PRK) in a cat model...
  14. pmc Visually-guided behavior of homonymous hemianopes in a naturalistic task
    Tim Martin
    Department of Ophthalmology, University of Rochester Medical Center, Rochester, NY 14642, USA
    Vision Res 47:3434-46. 2007
    ..Thus hemianopes displayed none of the compensatory gaze strategies seen in laboratory tasks. Instead, their gaze patterns suggest greater updating of, and greater reliance on a spatial representation...
  15. pmc Potentiation of femtosecond laser intratissue refractive index shaping (IRIS) in the living cornea with sodium fluorescein
    Lana J Nagy
    University of Rochester Eye Institute, Rochester, New York 14642, USA
    Invest Ophthalmol Vis Sci 51:850-6. 2010
    ..To assess the effectiveness of intratissue refractive index shaping (IRIS) in living corneas and test the hypothesis that it can be enhanced by increasing the two-photon absorption (TPA) of the tissue...
  16. pmc Intratissue refractive index shaping (IRIS) of the cornea and lens using a low-pulse-energy femtosecond laser oscillator
    Li Ding
    Institute of Optics, University of Rochester, Rochester, New York, USA
    Invest Ophthalmol Vis Sci 49:5332-9. 2008
    ..To assess the optical effect of high-repetition-rate, low-energy femtosecond laser pulses on lightly fixed corneas and lenses...
  17. pmc Photorefractive keratectomy in the cat eye: biological and optical outcomes
    Lana J Nagy
    Department of Ophthalmology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    J Cataract Refract Surg 33:1051-64. 2007
    ..To quantify optical and biomechanical properties of the feline cornea before and after photorefractive keratectomy (PRK) and assess the relative contribution of different biological factors to refractive outcome...
  18. pmc Electrophilic peroxisome proliferator-activated receptor-gamma ligands have potent antifibrotic effects in human lung fibroblasts
    Heather E Ferguson
    Department of Environmental Medicine, University of Rochester, Rochester, NY 14642, USA
    Am J Respir Cell Mol Biol 41:722-30. 2009
    ..As the inhibitory concentration causing a 50% decrease in aSMA for CDDO is 400-fold lower than that in rosiglitazone, the translational potential of CDDO for treatment of fibrotic diseases is high...

Research Grants7