Research Topics
| MICHELE REBECCA HUTCHISONSummaryAffiliation: University of Texas Southwestern Medical Center Country: USA Publications
Research Grants
| Collaborators
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Detail Information
Publications
BDNF alters ERK/p38 MAPK activity ratios to promote differentiation in growth plate chondrocytesMichele R Hutchison
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
Mol Endocrinol 26:1406-16. 2012....
Insulin-like growth factor-I and fibroblast growth factor, but not growth hormone, affect growth plate chondrocyte proliferationMichele R Hutchison
Division of Pediatric Endocrinology, Department of Pediatrics, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390 9063, USA
Endocrinology 148:3122-30. 2007..These results suggest that the major regulator of chondrocyte proliferation is systemic IGF-I; FGFs may influence the actions of IGF-I at the growth plate by altering its receptor number in chondrocytes...
SCF, BDNF, and Gas6 are regulators of growth plate chondrocyte proliferation and differentiationMichele R Hutchison
Division of Pediatric Endocrinology, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
Mol Endocrinol 24:193-203. 2010..IGF-I appears to be the primary proliferative signal in growth plate chondrocytes, whereas multiple factors including SCF, BDNF, and Gas6 regulate the pace of differentiation at the growth plate...
Vitamin D deficiency in obese children and its relationship to glucose homeostasisMicah L Olson
Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9063, USA
J Clin Endocrinol Metab 97:279-85. 2012....
Research Grants
- Examination of the Pre-pubertal Mammalian Growth PlateMICHELE HUTCHISON; Fiscal Year: 2007..The relevance to public health is to better understand mechanisms regulating bone growth in children, by using cells from young non-rodent animals for in vitro studies. ..
