Christopher D Huston

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. pmc Apoptotic killing and phagocytosis of host cells by the parasite Entamoeba histolytica
    Christopher D Huston
    Department of Medicine, University of Virginia Health System, Charlottesville 22908
    Infect Immun 71:964-72. 2003
  2. pmc Participation of the serine-rich Entamoeba histolytica protein in amebic phagocytosis of apoptotic host cells
    Jose E Teixeira
    Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Infect Immun 76:959-66. 2008
  3. pmc Entamoeba histolytica and Entamoeba dispar utilize externalized phosphatidylserine for recognition and phagocytosis of erythrocytes
    Douglas R Boettner
    Division of Infectious Diseases and International Health, P O Box 801340, Rm 2115, MR4 Building, University of Virginia Health System, Charlottesville, VA 22908 1340, USA
    Infect Immun 73:3422-30. 2005
  4. pmc Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase family
    Douglas R Boettner
    Department of Microbiology, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS Pathog 4:e8. 2008
  5. ncbi request reprint Identification and characterization of EhABC A1, an Entamoeba histolytica Group A ABC transporter with similarity to Ced-7
    Christopher D Huston
    Department of Medicine, University of Vermont College of Medicine, USA
    Mol Biochem Parasitol 146:272-6. 2006
  6. ncbi request reprint Kinetics and strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis
    Mami Okada
    Department of Parasitology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Mol Biochem Parasitol 145:171-83. 2006
  7. pmc Proteomic analysis of phagocytosis in the enteric protozoan parasite Entamoeba histolytica
    Mami Okada
    Department of Parasitology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Eukaryot Cell 4:827-31. 2005
  8. ncbi request reprint Parasite and host contributions to the pathogenesis of amebic colitis
    Christopher D Huston
    Department of Medicine, Division of Infectious Disease, University of Vermont College of Medicine, 304 Burgess Building, Fletcher Allen Health Care, 111 Colchester Avenue, Burlington, VT 05401, USA
    Trends Parasitol 20:23-6. 2004
  9. ncbi request reprint Amebiasis
    Rashidul Haque
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    N Engl J Med 348:1565-73. 2003
  10. pmc Evidence of a continuous endoplasmic reticulum in the protozoan parasite Entamoeba histolytica
    Jose E Teixeira
    Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Eukaryot Cell 7:1222-6. 2008

Collaborators

  • William Petri
  • Rashidul Haque
  • B J Mann
  • Jose E Teixeira
  • Douglas R Boettner
  • Mami Okada
  • Tomoyoshi Nozaki
  • Kiyoshi Kita
  • Eric Houpt
  • Alicia S Linford
  • Sarah N Buss
  • Nicholas E Sherman
  • Miho Oue
  • James A Sullivan

Detail Information

Publications10

  1. pmc Apoptotic killing and phagocytosis of host cells by the parasite Entamoeba histolytica
    Christopher D Huston
    Department of Medicine, University of Virginia Health System, Charlottesville 22908
    Infect Immun 71:964-72. 2003
    ..003). By analogy with phagocytic clearance during apoptosis in metazoans, amebic apoptotic host cell killing followed by phagocytosis may limit inflammation and enable amebae to evade the host immune response...
  2. pmc Participation of the serine-rich Entamoeba histolytica protein in amebic phagocytosis of apoptotic host cells
    Jose E Teixeira
    Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Infect Immun 76:959-66. 2008
    ..The results of this unbiased antibody screen strongly implicate the SREHP as a participant in E. histolytica phagocytosis and suggest that it may play an important role in adherence to apoptotic cells...
  3. pmc Entamoeba histolytica and Entamoeba dispar utilize externalized phosphatidylserine for recognition and phagocytosis of erythrocytes
    Douglas R Boettner
    Division of Infectious Diseases and International Health, P O Box 801340, Rm 2115, MR4 Building, University of Virginia Health System, Charlottesville, VA 22908 1340, USA
    Infect Immun 73:3422-30. 2005
    ..These findings establish phosphatidylserine involvement in erythrophagocytosis by amebae and suggest the existence of a PS receptor on the surfaces of both E. histolytica and E. dispar...
  4. pmc Entamoeba histolytica phagocytosis of human erythrocytes involves PATMK, a member of the transmembrane kinase family
    Douglas R Boettner
    Department of Microbiology, University of Virginia, Charlottesville, Virginia, United States of America
    PLoS Pathog 4:e8. 2008
    ..In conclusion, PATMK was identified as a member of the TMK family that participates in erythrophagocytosis and is uniquely required for intestinal infection...
  5. ncbi request reprint Identification and characterization of EhABC A1, an Entamoeba histolytica Group A ABC transporter with similarity to Ced-7
    Christopher D Huston
    Department of Medicine, University of Vermont College of Medicine, USA
    Mol Biochem Parasitol 146:272-6. 2006
  6. ncbi request reprint Kinetics and strain variation of phagosome proteins of Entamoeba histolytica by proteomic analysis
    Mami Okada
    Department of Parasitology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Mol Biochem Parasitol 145:171-83. 2006
    ..These data should provide significant insights into molecular characterization of phagosome biogenesis, and help to elucidate the pathogenesis of this important infection...
  7. pmc Proteomic analysis of phagocytosis in the enteric protozoan parasite Entamoeba histolytica
    Mami Okada
    Department of Parasitology, Gunma University Graduate School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Eukaryot Cell 4:827-31. 2005
    ..Phagosome localization of representative proteins was verified by immunofluorescence assay. This study should provide a basis for molecular identification and characterization of phagosome biogenesis...
  8. ncbi request reprint Parasite and host contributions to the pathogenesis of amebic colitis
    Christopher D Huston
    Department of Medicine, Division of Infectious Disease, University of Vermont College of Medicine, 304 Burgess Building, Fletcher Allen Health Care, 111 Colchester Avenue, Burlington, VT 05401, USA
    Trends Parasitol 20:23-6. 2004
  9. ncbi request reprint Amebiasis
    Rashidul Haque
    International Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh
    N Engl J Med 348:1565-73. 2003
  10. pmc Evidence of a continuous endoplasmic reticulum in the protozoan parasite Entamoeba histolytica
    Jose E Teixeira
    Department of Medicine, University of Vermont College of Medicine, Burlington, VT 05405, USA
    Eukaryot Cell 7:1222-6. 2008
    ..Here, using an ER-targeted green fluorescent protein fusion protein and fluorescence loss in photobleaching, we have unambiguously demonstrated the presence of a continuous ER compartment in living E. histolytica trophozoites...