Donna M Huryn

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators
    Donna M Huryn
    University of Pittsburgh Center for Chemical Methodologies and Library Design, Chevron Science Center, Parkman Avenue, Pittsburgh, PA 15260, USA
    Proc Natl Acad Sci U S A 108:6757-62. 2011
  2. doi request reprint HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus
    Paul A Johnston
    Pittsburgh Molecular Library Screening Center, Department of Pharmacology, University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Assay Drug Dev Technol 5:737-50. 2007

Detail Information

Publications2

  1. pmc Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators
    Donna M Huryn
    University of Pittsburgh Center for Chemical Methodologies and Library Design, Chevron Science Center, Parkman Avenue, Pittsburgh, PA 15260, USA
    Proc Natl Acad Sci U S A 108:6757-62. 2011
    ..These projects highlight the importance of chemical methodology development as a source of small-molecule probes and as a drug discovery starting point...
  2. doi request reprint HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virus
    Paul A Johnston
    Pittsburgh Molecular Library Screening Center, Department of Pharmacology, University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Assay Drug Dev Technol 5:737-50. 2007
    ..We also provide the structural basis for additional species-selective allosteric inhibitors of flaviviruses...