Donna M Huryn
Affiliation: University of Pittsburgh
- Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulatorsDonna M Huryn
University of Pittsburgh Center for Chemical Methodologies and Library Design, Chevron Science Center, Parkman Avenue, Pittsburgh, PA 15260, USA
Proc Natl Acad Sci U S A 108:6757-62. 2011..These projects highlight the importance of chemical methodology development as a source of small-molecule probes and as a drug discovery starting point...
- HTS identifies novel and specific uncompetitive inhibitors of the two-component NS2B-NS3 proteinase of West Nile virusPaul A Johnston
Pittsburgh Molecular Library Screening Center, Department of Pharmacology, University of Pittsburgh Drug Discovery Institute, University of Pittsburgh, Pittsburgh, PA 15260, USA
Assay Drug Dev Technol 5:737-50. 2007..We also provide the structural basis for additional species-selective allosteric inhibitors of flaviviruses...