- The retinitis pigmentosa protein RP2 interacts with polycystin 2 and regulates cilia-mediated vertebrate developmentToby Hurd
Department of Pediatrics and Communicable Diseases, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA
Hum Mol Genet 19:4330-44. 2010..This work suggests that RP2 may be an important regulator of ciliary function through its association with polycystin 2 and provides evidence of a further link between retinal and renal cilia function...
- 3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotideAmiya K Ghosh
Department of Pediatrics, University of Michigan Health System, 1150 West Medical Center Dr, Ann Arbor, MI 48109 5646, USA
Am J Physiol Renal Physiol 303:F1225-9. 2012..This study reveals that the loss of Nphp3, Nphp6, or Nphp8 leads to cilia abnormalities and cell polarity defects, resulting in spheroid abnormalities, which can be rescued by inhibiting cAMP levels with octreotide treatment...